Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Chemotherapy  (2)
  • peripheral plasma renin activity  (2)
  • Acquired immunodeficiency syndrome  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Treatment of atypical leishmaniasis with interferon γ resulting in progression of Kaposi's sarcoma in an AIDS patient (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 1041-1047 
    Details
    ISSN: 1432-1440
    Keywords: Acquired immunodeficiency syndrome ; Human immunodeficiency virus ; Leishmania donovanii ; Visceral leishmaniasis ; Kala-azar ; Intestinal pathogens ; Kaposi's sarcoma ; Parasites ; Parasitic pathogens ; Interferon-γ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Visceral leishmaniasis (kala-azar) affecting HIV-infected patient is being reported in increasing frequency. A 40-year-old German bisexual patient with full-blown AIDS is described who presented with Kaposi's sarcoma, epigastric pain, diarrhea, and weight loss but without fever.Leishmania amastigotes were initially found in biopsies from stomach, duodenum, and a cutaneous Kaposi's sarcoma lesion but were later also recovered from bone marrow and lymph node. The patient received three courses of a combination of pentavalent antimony and interferon-γ. In addition to the common side effects such as fever, thrombocytopenia, and elevated amylase and lipase, a vivid progression of the Kaposi's sarcoma was noted. Tumor progression was temporally closely associated with treatment with interferon-γ. Because this phenomemon has also been observed in other patients, we advise caution when using interferon-γ in patients with Kaposi's sarcoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00577752
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Myocardial infarction in young patients with Hodgkin's disease — potential pothogenic role of radiotherapy, chemotherapy, and splenectomy (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 57-64 
    Details
    ISSN: 1432-1440
    Keywords: Myocardial infarction ; Hodgkin's disease ; Radiation therapy ; Chemotherapy ; Splenectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Among a total of 2147 patients admitted to our hospital for acute myocardial infarction between 1978 and 1987, three young patients aged 24, 29, and 39 years had previously been treated for Hodgkin's disease. Staging laparotomy, including splenectomy, had been performed in all three patients. Two patients had both mediastinal irradiation (21 and 27 months before infarction) and chemotherapy. In the first patient, postmortem histologic examination of the coronary arteries revealed fibrotic changes, which were probably induced by radiotherapy. In our second patient, myocardial infarction developed 5 days after vinblastine treatment; early angiography showed thrombotic occlusion of the proximal right coronary artery, which was recanalized using the diagnostic Sones catheter. Subsequent angiography revealed normal coronary arteries. This is, to our knowledge, the first case of documented coronary artery thrombosis after treatment with vinca-alkaloids. In our third patient, neither mediastinal irradiation nor chemotherapy had been performed prior to myocardial infarction. However, a marked increase in platelet counts following splenectomy was observed in this patient. The role of radiotherapy, chemotherapy, and splenectomy with consecutive thrombocytosis as a third possible pathogenic factor for subsequent development of myocardial infarction is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210966
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Tubular function and histological findings in ifosfamide-induced renal Fanconi syndrome — a report of two cases (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 384-387 
    Details
    ISSN: 1432-1076
    Keywords: Renal Fanconi syndrome ; Ifosfamide ; Nephrotoxicity ; Chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two patients developed renal Fanconi syndrome (RFS) after intensive long-term chemotherapy for metastatic Ewing sarcoma and disseminated neuroblastoma. Whereas RFS was diagnosed in patient 1 before he developed osteomalacia, patient 2 experienced severe rickets and growth retardation. Renal function studies revealed slight glomerular impairment and severe tubular defects leading to increased excretion of glucose, amino acids, inorganic phosphate and low molecular weight proteins, indicating proximal tubular damage. Patient 2 additionally showed distal tubular dysfunction with acidosis and diminished concentrating capacity. Renal biopsy in patient 1 revealed marked proximal tubular defects without interstitial lymphocytic infiltration. In both patients renal damage could most likely be ascribed to previous ifosfamide (IFOS) therapy. Our patients showed no improvement in renal function after cessation of IFOS treatment, indicating a poor prognosis of once established RFS after IFOS therapy. Measurement of tubular reabsorption capacities provides exact information on the extent of tubular toxicity induced by IFOS and may be used to monitor IFOS treated patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113264
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Plasma renin activity in folic acid induced acute renal failure (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 797-798 
    Details
    ISSN: 1432-1440
    Keywords: Folic acid ; acute renal failure ; macula densa ; peripheral plasma renin activity ; hemorrhage ; Folsäure ; akutes Nierenversagen ; Macula densa ; periphere Plasma-Reninaktivität ; Hämorrhagie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die periphere Plasma-Reninaktivität war bei Ratten mit akutem Nierenversagen, das durch eine einmalige i.v. Injektion von Folsäure (250 mg/kg KG, gelöst in 0,3 M NaHCO3) erzeugt worden war, während der ersten 6 Std normal und nach 24 Std und 4 Tagen harabgesetzt. Hämorrhagie verursachte jedoch am 4. Tag nach Folsäuregabe einen starken Anstieg der Plasma-Reninaktivität. Für eine Beteiligung des Renins an der Entwicklung des folsäurebedingten funktionellen und morphologischen Nierenschadens ergab sich kein Anhalt.
    Notes: Summary Peripheral plasma renin activity in acute renal failure induced in rats by a single i.v. injection of folic acid (250 mg/kg b. w., dissolved in 0.3 M NaHCO3) remained normal during the first 6 hours and fell to low levels 24 hours and 4 days following the injection. Bleeding, however, induced a considerable increase of plasma renin activity on the 4th day after folate injection. There was no evidence of a participation of renin in the development of the functional and morphological renal disturbances produced by folic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01490312
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Renin secretion in the earliest stage of goldblatt-type hypertension in rats (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 841-844 
    Details
    ISSN: 1432-1440
    Keywords: Early experimental renal hypertension ; renal artery constriction ; unilateral nephrectomy ; renal venous plasma renin activity ; peripheral plasma renin activity ; Frühe experimentelle renale Hypertonie ; Nierenarteriendrosselung ; einseitige Nephrektomie ; Plasma-Reninaktivität im Nierenvenenblut ; periphere Plasma-Reninaktivität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Einseitige Nephrektomie und gleichzeitige Drosselung der verbliebenen kontralateralen Nierenarterie führten bei der Ratte nach 90 min zu einer signifikanten, bis zum Versuchsende (24 Std) anhaltenden Erhöhung des systolischen arteriellen Blutdruckes und zu einer vorübergehenden Zunahme der Plasma-Reninaktivität, die nach 3 Std wieder zur Norm abfiel. Einseitige Nephrektomie allein verursachte nach 90 und 180 min einen signifikanten Blutdruckabfall, nach 20 und 45 min eine geringe Steigerung der Reninaktivität im Nierenvenenblut und nach 3 Std eine bis zur 24. Std signifikant erniedrigte periphere Plasma-Reninaktivität. Eine Steigerung der Reninsekretion der „geklammerten“ Niere könnte daher für den initialen Blutdruckanstieg bei Ratten mit einer Hypertonie vom Goldblatt-Typ von Bedeutung sein.
    Notes: Summary Unilateral nephrectomy and constriction of the remaining renal artery in the rat induced a sustained increase of systolic blood pressure, which becomes significant as soon as 90 minutes after operation, and a transient rise in renal venous as well as in peripheral plasma renin activity between 20 and 180 minutes after operation. Unilateral nephrectomyper se, after 90 and 180 minutes, caused a significant fall of the systolic blood pressure, a slight increase of renal venous renin activity after 20 and 45 minutes, and between 3 and 24 hours after operation it was followed by a significant decrease of peripheral plasma renin activity. An increased secretion of renin from the “clamped” kidney may thus contribute to the initial rise of blood pressure in rats with Goldblatt-type hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01496342
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...