ISSN:
1432-2307
Keywords:
Cystadenolymphoma
;
Salivary gland
;
Histogenesis
;
Cytokeratin
;
Vimentin
;
Glial fibrillary protein (GFP)
;
Co-expression
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The distribution of selective cytokeratin polypeptides, vimentin, and glial fibrillary protein (GFP) in 5 human cystadenolymphomas of the parotid gland was compared with normal human parotid (n=5) and submandibular (n=4) glands using a panel of monoclonal antibodies against diverse and selective cytokeratin polypeptides, vimentin and glial fibrillary protein (GFP). A biotin-streptavidin method was used on cryostat sections. The immunocytochemical finding of identical cytokeratin polypeptides Nos. 7, 8, 18 and 19 and basal cells selectively labeled by the monoclonal antibody KS 8.58, in both the epithelial part of the cystadenolymphomas and in the duct epithelium of the parotid gland, confirms the hypothesis that the epithelial compartment of cystadenolymphomas is derived from the duct system. The triple expression of cytokeratin, vimentin and GFP in myoepithelial cells of the parotid gland is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00713290
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