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  • 1
    ISSN: 1432-2307
    Keywords: Cystadenolymphoma ; Salivary gland ; Histogenesis ; Cytokeratin ; Vimentin ; Glial fibrillary protein (GFP) ; Co-expression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of selective cytokeratin polypeptides, vimentin, and glial fibrillary protein (GFP) in 5 human cystadenolymphomas of the parotid gland was compared with normal human parotid (n=5) and submandibular (n=4) glands using a panel of monoclonal antibodies against diverse and selective cytokeratin polypeptides, vimentin and glial fibrillary protein (GFP). A biotin-streptavidin method was used on cryostat sections. The immunocytochemical finding of identical cytokeratin polypeptides Nos. 7, 8, 18 and 19 and basal cells selectively labeled by the monoclonal antibody KS 8.58, in both the epithelial part of the cystadenolymphomas and in the duct epithelium of the parotid gland, confirms the hypothesis that the epithelial compartment of cystadenolymphomas is derived from the duct system. The triple expression of cytokeratin, vimentin and GFP in myoepithelial cells of the parotid gland is discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 304-306 
    ISSN: 1434-4726
    Keywords: Laryngeal neoplasms ; Mixed salivary gland tumor ; Pleomorphic adenoma surgery ; Pleomorphic adenoma pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Tumors arising from minor salivary glands are extremely rare neoplasms in the larynx. Of the few reports of pleomorphic adenomas in this site , most have subglottic locations while only one case has involved the true vocal cord and seven cases have had supraglottic locations. We present a case of benign mixed tumor located in the posterior commissure which, to our knowledge, is the first reported in the world literature.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 36 (1996), S. 207-216 
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Sonographie ; Kopf-Hals-Tumoren ; Staging ; Treffsicherheit ; Key words Ultrasound ; Head and neck tumors ; Staging ; Accuracy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The radiologic imaging methods play an important role in the precise staging as basic requirement for an effective concept of tumor therapy. The accuracy of ultrasound in the primary staging according to the TNM-classification (UICC) was therefore prospectively investigated in 260 patients with head and neck tumors of the clinical stages T1N0 to T4N3. The clinically (C1) and sonographically (C2) evaluated pretherapeutic stages were compared to the postoperative histopathologic tumor classifications. The clinical staging was correct in 75.0 %, high in 7.7 %, low in 17.3 %, the N-stages were correct in 59.2 %, high in 17.7 %, low in 23.1 %. The sonographic staging was apparently superior with the T-classifications correct in 92.3 %, high in 7.7 %, low 0.0 %. The N-stages were correct in 89.6 %, high in 9.2 %, low in 1.2 %. The accuracy of combined TN classification rose from clinical 46.5 % to 84.6 % by sonography. Accompanying inflammations, foregoing biopsies and tooth extractions were the main reasons for incorrect staging. Therefore, the thorough sonographic investigation performed after the clinical examination and before invasive procedures, due to little patient discomfort, good availability and high accuracy, is an excellent sectional imaging method for staging, therapy-planning and follow up of tumors of the head and neck especially of the orofacial regions.
    Notes: Zusammenfassung Für eine genaue Stadienzuordnung als Grundvoraussetzung eines effektiven Tumortherapiekonzeptes spielen die bildgebenden radiologischen Verfahren eine entscheidende Rolle. Daher wurde die Treffsicherheit der Sonographie im TNM-Primärstaging gem. UICC bei 260 Patienten mit Kopf-Hals-Tumoren der klinischen Stadien T1N0 bis T4N3 prospektiv untersucht. Die prätherapeutischen klinischen (C1) und sonographischen (C2) Stadien wurden mit den postoperativen histopathologischen Tumorformeln verglichen. Klinisch war das T-Stadium korrekt in 75,0 %, zu hoch 7,7 %, zu tief 17,3 %, das N-Stadium korrekt in 59,2 %, zu hoch 17,7 %, zu tief 23,1 %. Deutlich überlegen die Sonographie mit T korrekt in 92,3 %, zu hoch 7,7 %, zu tief 0,0 %, N korrekt in 89,6 %, zu hoch 9,2 %, zu tief 1,2 %. Die Treffsicherheit stieg von 46,5 % für das klinische auf 84,6 % für das sonographische kombinierte TN-Staging. Begleitentzündungen, voraufgegangene Biopsien oder Zahnextraktionen waren Hauptursachen für Fehlklassifikationen. Somit stellt die Sonographie, durchgeführt im Anschluß an die klinische Untersuchung und vor invasiven Maßnahmen bei geringer Belastung, guter Verfügbarkeit und hoher Aussagefähigkeit ein hervorragendes Schnittbildverfahren zu Staging, Therapieplanung und Verlaufskontrolle von Kopf-Hals-Tumoren, insbesondere der orofazialen Regionen, dar.
    Type of Medium: Electronic Resource
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