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  • 1
    Electronic Resource
    Electronic Resource
    Extracorporeal shockwave lithotripsy (ESWL) and endourology: an ideal combination for the treatment of kidney stones (1985)
    Springer
    World journal of urology 3 (1985), S. 41-47 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Operative management of renal calculi has changed radically in the past decade. New imaging techniques for intraoperative stone localization, the use of cooling techniques and drugs to protect renal function, and new operative techniques have even made possible the removal of complete staghorn calculi in short and kidney-preserving procedures. Considerable morbidity, however, still results from conventional renal stone surgery, especially when repeated operations are necessary for recurrent stone disease. Since the introduction of new less invasive methods, such as percutaneous nephrolithotomy (PCN) and stone extraction using an especially designed ureteroscope (URS), and above all, since the clinical application of extracorporeal shock wave lithotripsy (ESWL), policies for stone management have changed completely. A review of 1340 consecutive patients presenting with stones between October 1983 and October 1984 shows that only 7% of all patients with urinary stones — 1% of all renal stones and 15% of all ureteral stones — still required an open operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326887
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  • 2
    Electronic Resource
    Electronic Resource
    Treatment of ureteral stone disease: the role of ESWL and endourology (1985)
    Springer
    World journal of urology 3 (1985), S. 53-57 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In recent years, extracorporeal shockwave lithotripsy (ESWL) has proved a safe and easily reproducible method for the treatment of calculi in the upper urinary tract above the iliac crest. Current indications for ESWL as single therapy encompass approximately 60%–70% of all stones. The use of endourological methods as auxiliary procedures can enhance the range of indications to 95% of all renal stones and 85% of all ureteral stones. In the last year, 1340 patients have been successfully treated for urinary calculi at our department. Evaluation of all stone cases shows that ESWL alone, ESWL combined with percutaneous techniques, or percutaneous techniques alone were performed on 93% of all patients. Only 7% of patients had to undergo open surgical treatment, 1% for renal stones and 15% for ureteral stones. Ureteral stones are still among the problem stones for ESWL, in many cases requiring time-consuming combined procedures with either of the percutaneous methods. Furthermore, ureteral obstruction caused by stone particles as a complication after ESWL-treatment of large renal stones has to be relieved using percutaneous techniques. In this report we describe our approach in detail and discuss our results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326889
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  • 3
    Electronic Resource
    Electronic Resource
    Erratum (1990)
    Springer
    World journal of urology 8 (1990), S. 178-178 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01576768
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  • 4
    Electronic Resource
    Electronic Resource
    ESWL and the future of stone management (1993)
    Springer
    World journal of urology 11 (1993), S. 2-6 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Based on optimal efficacy regarding disintegration and stone clearance, combined with minimal invasiveness, extracorporeal shockwave lithotripsy (ESWL) represents the first choice therapy for urolithiasis. Further developments in ESWL have related more to economic aspects than to improvement of disintegration efficacy or reduction of side effects. Routine indications for ESWL are well known and widely accepted. Its limitations are also well established: silent calyceal stones, calyceal diverticula stones, nephrolithiasis in horse-shoe kidneys, medullary sponge kidney, and residual fragments after ESWL. Although endourology provides new, less invasive and traumatic means of stone retrieval or disintegration, including laser lithotripsy, small ureteroscopes and actively deflectable uretero- and pyeloscopes, indications for an aggressive approach in such cases are limited to those who are symptomatic. In the case of distal ureteral calculi ureteroscopy in traureteral laser-induced shockwave lithotripsy open up new and interesting possibilities for the future.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00182162
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  • 5
    Electronic Resource
    Electronic Resource
    Extracorporeal piezoelectric lithotripsy using the Wolf-lithotriptor versus low energy lithotripsy with the modified Dornier HM-3: a cooperative study (1987)
    Springer
    World journal of urology 5 (1987), S. 218-224 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In January 1986, a cooperative study was started at the Katharinenhospital in Stuttgart, FRG (modified Dornier HM-3) and Kreiskrankenhaus in Kempten, FRG (Wolf Piezolith 2200) to evaluate the range of indications, efficacy and required anesthesia of both lithotriptors. Stone classification and general indications for interventional therapy were similar in both centers. The Dornier HM-3 operates with a modified generator and a new ellipsoid which provide low pressure lithotripsy. With the Piezolith 2200, 99% of ESWL-treatments were performed without any anesthesia, whereas with the modified Dornier HM-3 lithotriptor, minor analgesia using tramadol was necessary in 92%, epidural anesthesia in 8%. The overall success rate was similar in both centers (Piezolith 2200: 94.5% vs Dornier HM-3: 98%). Only 46% of the patients were treated successfully in one session with the Wolf lithotriptor compared to 88% with the Dornier HM-3. Ultrasound localization with the Piezolith 2200 failed in 58% of ureteral calculi, whereas fluoroscopic stone localization (Dornier HM-3) was insufficient in the majority of slightly or nonopaque calculi.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00327224
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  • 6
    Electronic Resource
    Electronic Resource
    Methotrexate, vinblastine, 4′-epirubicin and cisplatin in advanced urothelial tract tumors: Efficacy and toxicity (1990)
    Springer
    World journal of urology 8 (1990), S. 51-54 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report the efficacy and toxicity of combined methotrexate, vinblastine, 4′-epirubicin and cisplatin (M-VEC) for the treatment of advanced urothelial tract tumors in 58 evaluable patients. Histologically, the patients had pure transitional-cell carcinoma (89.7%), squamous-cell carcinoma (8.6%) and anaplastic carcinoma (1.7%). Locally advanced disease (pT3-4 N0 M0) was present in 22 patients (37.9%); pelvic lymphnode metastases (pT3-4 N1-3 M0), in 20 (34.5%); and metastatic disease, in 16 (27.6%). Response was observed in 72.3% of the patients, with complete remission achieved by 51.7%. Response rates and survival were influenced by histological subtype and tumor stage. Squamous-cell carcinoma did not respond to M-VEC chemotherapy. There was one drug-related death (1.7%); otherwise, toxicity was mild to moderate. Adverse effects included cardiac toxicity (9%), mucositis (5.1%), nadir sepsis (1.7%) and renal failure (1.7%) in a small number of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01576278
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  • 7
    Electronic Resource
    Electronic Resource
    Differentiated approach to staghorn calculi using extra-corporeal shock wave lithotripsy and percutaneous nephro-lithotomy: an analysis of 151 consecutive cases (1987)
    Springer
    World journal of urology 5 (1987), S. 248-254 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary From January 1984 to June 1986, 151 patients with partial or complete staghorn calculi were treated at our department either by extracorporeal shock wave lithotripsy (ESWL), percutaneous nephro-lithotomy (PCN) or a combination of both techniques. According to the stone burden, distribution of stone load, renal anatomy, radiodensity and chemical composition of the calculi, 31 patients (20%) underwent ESWL-monotherapy, 42 patients (28%) PCN-monotherapy, and 78 (52%) were treated by the combination (PCN+ESWL). The overall rate of severe complications amounted to 8%. Auxiliary measures were necessary in 35% after ESWL-monotherapy, 19% after PCN-monotherapy and 14% after the combination. Follow-up data with a mean observation time of 18 months were available for 89 patients: the stone-free rate for ESWL, PCN and the combination was 50%, 77%, and 60%, respectively. Recurrent stone formation occurred in 4% after PCN and in 6% after the combination. The incidence of urinary tract infection was significantly lower than before treatment (21% vs 36%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00327229
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  • 8
    Electronic Resource
    Electronic Resource
    Experimental xenogeneic kidney transplantation in closely related species (1973)
    Springer
    Research in experimental medicine 159 (1973), S. 266-275 
    Details
    ISSN: 1433-8580
    Keywords: Kidney-transplantation ; Xenotransplantation ; Closely related species ; Delayed hyperacute rejection ; Nierentransplantation ; Xenotransplantation ; Nah verwandtes System ; Verzögert hyperakute Abstoßung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Um das Verhalten vascularisierter Xenotransplantate zwischen Tieren enger zoologischer Verwandtschaft zu untersuchen, wurden Katzennieren „en bloc“ auf Hunde transplantiert. In diesem System zeigte sich, mit einer Funktionsdauer von 15–24 Std, der Typ einer verzögert hyperakuten Abstoßung. Der Abfall des Komplements im peripheren Blut und das Auftreten von Katzenprotein im Urin schon während der ersten Stunden deutet auf einen früheren Beginn dieser Reaktion hin, während die endgültige Zerstörung des Transplantates durch unspezifische, jedoch von der Antigen-Antikörper-Reaktion gestartete Mechanismen bedingt zu sein scheint. Den Empfängern dieser Ersttransplantate wurden 3 Wochen später mit einer Ex vivo-Hämoperfusion eine zweite Katzenniere angeschlossen. Innerhalb von 15–20 min waren diese Nieren unter dem Bild einer typischen hyperakuten Abstoßung zerstört.
    Notes: Summary To study the survival time of kidney-transplants in closely related species cat kidneys were transplanted to the iliac vessels of mongrel dogs by an “en bloc” method. A type of delayed hyperacute rejection was observed. The function time of the transplant kidneys ranged from 15 to 24 hrs. The decrease of complement activity and the appearance of cat-tissue protein in serum and urine samples show that the rejection began at an early stage. Since the antigen-antibody reaction seems to be finished after 6 hrs, indicated by an increase of complementactivity, the final loss of function may be effected by an unspecific reaction. Recipients survived after removal of the transplant and got a second kidney graft 3 weeks after the first set. These kidneys were rejected within 15–20 min with the sign of typical hyperacute rejection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851601
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  • 9
    Electronic Resource
    Electronic Resource
    24 Hour-Monitoring of patients with bladder voiding disturbances (1981)
    Springer
    Urological research 9 (1981), S. 187-191 
    Details
    ISSN: 1434-0879
    Keywords: Cystometry ; Long-term monitoring ; Bed-wetting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A system was developed and built for recording and processing urodynamic measurements during a 24 h period. The essential requirement was to obtain these signals without psychological stress. The system was small enough to allow the patient to move freely. Semiconductor pressure transducers were employed for measuring total bladder and rectal pressures and detrusor pŕessure was obtained by subtraction. Results gained with this method revealed some differences to those obtained with conventional methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00264825
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  • 10
    Electronic Resource
    Electronic Resource
    Changes in blood flow and vasculature of the dog kidney undergoing normothermic and hypothermic ischaemia (1977)
    Springer
    Urological research 5 (1977), S. 7-13 
    Details
    ISSN: 1434-0879
    Keywords: Hypothermia ; Ischaemia ; Renal blood flow ; Xenon wash out technique ; Sequential renal scanning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 11 mongrel dogs both kidneys have been subjected to a 2 h ischaemic period. One kidney was cooled by perfusing the renal artery at 4°C while the contralateral normothermic kidney was clamped for 2 h. Studying the renal blood flow using the Xenon wash out technique, sequential renal scanning and angiography, marked differences between hypo- and normothermic ischaemia kidneys were observed. One or two hours following hypothermic perfusion a marked decrease of blood flow in the first compartment and vasoconstriction was evident, while within this period following normothermic ischaemia an enhanced renal blood flow was observed. After 24 h renal blood flow and renal function tested by 131I-Hippuran clearance returned to normal values. Angiographic studies corresponded to the preoperative findings. In contrast, normothermic ischaemia kidneys showed a decreased renal blood flow, impairment of kidney function in isotope studies and pathological angiographic changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257110
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