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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 55 (1977), S. 137-140 
    ISSN: 1432-1440
    Keywords: Psoralen ; UVA ; Lymphocyt ; Photochemotherapie ; Psoriasis ; Psoralen ; UVA ; Lymphocyte ; Photochemotherapy ; Psoriasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The effect of psoralen plus long wavelength ultraviolet light (UVA) on3H-thymidine uptake of PHA stimulated human lymphocytes was investigated. PHA induced lymphocyte transformation was inhibited by the combined action of psoralen and UVA irradiation in a dose related manner. Inhibition of DNA-synthesis occurred at concentrations of psoralen that can be expected in the serum of patients treated by systemic photochemotherapy. No effect was noted at these psoralen concentrations in the absence of UVA irradiation. Also did UVA irradiation in the absence of psoralen not inhibit3H-thymidine incorporation into PHA stimulated lymphocytes.
    Notes: Zusammenfassung Es wurde die Wirkung von Psoralen zusammen mit langwelligem ultraviolettem Licht (UVA) auf den3H-Thymidin-Einbau PHA-stimulierter humaner Lymphocyten untersucht. Die PHA-induzierte Lymphocytentransformation wurde durch Psoralen plus UVA gehemmt, abhängig sowohl von der Psoralenkonzentration als auch der Einwirkdauer der UVA-Bestrahlung. Die Hemmung der DNA-Synthese in den stimulierten Lymphocyten erfolgte bei Psoralenkonzentrationen wie sie auch im Serum von Patienten erwartet werden können, die sich einer systemischen Photochemotherapie unterziehen. Ohne UVA-Bestrahlung war bei diesen Psoralenkonzentrationen kein Effekt auf die DNA-Synthese nachweisbar. Ebenso erwies sich alleinige UVA-Bestrahlung ohne Psoralenzusatz als wirkungslos auf das Wachstum PHA-stimulierter Lymphocytenkulturen.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Keywords: Cortical mapping; compound motor action potentials; motor pathways; intraoperative monitoring.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ Intra-operative neurophysiological techniques allow reliable identification of the sensorimotor region and make their anatomical and functional preservation feasible. Monopolar cortical stimulation has recently been described as a new mapping technique. In the present study this method was compared to the “traditional” technique of bipolar stimulation.  Functional mapping of the motor cortex was performed in 35 patients during surgery in the central region. The central sulcus (CS) was identified by somatosensory evoked potential (SEP) phase reversal. Cortical motor mapping was first performed by monopolar anodal stimulation with a train of 500 Hz (7–10 pulses) followed by bipolar stimulation (pulses at 60 Hz with max. 4 sec train duration). Surgery was performed under general anaesthesia without muscle relaxants. Of 280 motor responses elicited by bipolar cortical stimulation, 54.28% [152] were located in the primary motor cortex (PMC), 37.85% [106] outside the motor strip in the secondary motor cortex (SMC), and 8% [22] posterior to the CS. Of 175 motor responses elicited by monopolar cortical stimulation, 68.57% [120] were located in the SMC, 23.42% [41] in the SMC and 8% [14] posterior to the CS.  Contrary to the general clinical view, there is considerable overlapping of primary motor units over a cortical area much broader than the “classical” narrow motor strip along the CS. Bipolar cortical stimulation is more sensitive than monopolar for mapping motor function in the premotor frontal cortex. Both methods are equally sensitive for mapping the primary motor cortex.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0942-0940
    Keywords: Keywords: Cerebral plasticity; cortical stimulation; monopolar cortical stimulation; motor cortex.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  It has been postulated long ago that “eloquent” areas shift their location in patients with arteriovenous malformations (AVM). Obviously the “motor region” in not located in the precentral gyrus in a patient with an AVM in the “motor region”.  We report on the case of a 15-year old boy with an AVM in the left sensorimotor cortex, in whom intra-operative mapping showed an inexcitability of the precentral gyrus, while stimulation of the cortex anterior to the primary motor cortex elicited motor responses. This indicates that motor function was translocated from the primary to the supplementary motor cortex. Surgery was performed under general anaesthesia. Neurophysiological monitoring was performed throughout surgery. The central sulcus was identified by phase reversal of the somatosensory evoked potentials. The motor cortex was mapped by direct high-frequency (500 Hz) monopolar anodal stimulation.  In the patient herein reported, stimulation of the “anatomically” defined primary motor cortex induced no motor response, as expected. Motor response was elicited only by stimulation of the cortex anterior to the precentral gyrus. There was no postoperative deterioration of motor function. These observations indicate that the precentral gyrus was functionally “useless”. The motor region was relocated into more rostral areas in the supplementary motor cortex. This translocation of function in the presence of an AVM indicates cerebral plasticity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillian Magazines Ltd.
    Nature 417 (2002), S. 527-529 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Anomalous X-ray pulsars (AXPs) differ from ordinary radio pulsars in that their X-ray luminosity is orders of magnitude greater than their rate of rotational energy loss, and so they require an additional energy source. One possibility is that AXPs are highly magnetized neuron stars—or ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillian Magazines Ltd.
    Nature 418 (2002), S. 211-211 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nature 417, 527–529 (2002). In the second sentence of this Letter, the word ‘neuron’ appears incorrectly. It should read ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry 17 (1925), S. 74-74 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 7
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    Unknown
    Berlin : Periodicals Archive Online (PAO)
    Kant-Studien. 15 (1910) 512 
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Der Gynäkologe 33 (2000), S. 699-702 
    ISSN: 1433-0393
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Die Kläger sind die Eltern eines am 29.4.1989 mit einer schweren Form von Mongolismus (Trisomie 21) geborenen Kindes. Der Beklagte betreute die damals 42-jährige Klägerin vor und während der Schwangerschaft. Er war auch der Geburtshelfer. Für die Klägerin war es die 3. Schwangerschaft.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 159 (1960), S. 178-193 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The Si Kβ-emission bands of silicon, carborundum and quartz, hitherto unknown or known inaccurately were photographed using a high-dispersion focusing spectrograph. The results are presented in form of photometer curves and in a table giving the energy values for structural features. For silicon, carborundum and quartz all emission bands of the elements concerned are now known. A comparision of the emissions, together with that from diamond, indicates that the spectra essentially represent the form of the energy bands of the valency electrons and that they are little influenced by unusual excited states. The emission bands of silicon, carborundum and diamond show to a great extent similar features thereby indicating an essentially covalent type of bonding in all cases including carborundum. The emission forms are in rough agreement with the calculated valency band structures.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 174 (1963), S. 372-375 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Durch genaue photometrische Vermessung photographischer Aufnahmen, die unter Verwendung eines fokussierenden Spektrographen großer Dispersion erhalten wurden, ergab sich im Gegensatz zu früheren Messungen, daß die CuKα 1-Linie von CuO gegenüber derjenigen von metallischem Kupfer um einen zwar kleinen, aber meßbaren Betrag nach kürzeren Wellenlängen verschoben ist. Bei Kathodenstrahlerregung wurde die Verschiebung zu −0,021±0,008 X oder +0,11±0,04 eV, bei Fluoreszenzerregung zu −0,029±0,006 X oder +0,15±0,03 eV gemessen. Diese Verschiebung der CuKα 1-Linie ist wesentlich kleiner als sie nachβ-spektroskopischen Messungen der Bindungsenergien derK- undL-Elektronen des Kupfers im Metall und Oxyd sein sollte.
    Type of Medium: Electronic Resource
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