Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-0533
    Keywords: Key words Human pineal gland ; Pineal parenchymal tumors ; Ultrastructure ; Chromogranin A
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have studied 20 pineal parenchymal tumors (PPT) and 4 normal or cystic pineal glands both by light and electron microscopy and immunohistochemistry with antibodies against glial markers [glial fibrillary acidic protein (GFAP) and protein S-100] or neural/neuroendocrine markers [neurofilaments (NF), synaptophysin and chromogranin A]. Light microscopy revealed the cellular organization of pinealocytes in the normal gland and in different morphological types of pineal tumors (typical pineocytomas, PPT with intermediate differentiation, mixed PPT exhibiting elements of both pineocytoma and pineoblastoma and pineoblastomas). Immunohistochemistry showed the presence of GFAP and protein S-100 in interstitial cells in non-neoplastic pineal gland. Cell processes were labeled with anti-synaptophysin and anti-NF antibodies. No immunoreactivity was found for chromogranin A in non-neoplastic pineal gland. In pineocytomas, GFAP and protein S-100 were observed in interstitial cells. Synaptophysin and NF were present in the large rosettes of pineocytomas. Synaptophysin, NF and chromogranin A were present in pineocytomas with a lobular arrangement of cells. Anti-chromogranin A immunoreactivity was also seen in lobular areas of some PPT with intermediate differentiation. Analysis of normal human pineal gland by electron microscopy showed the presence of vesicle-crowned rodlets (VCR or synaptic ribbons), fibrous filaments (F), paired twisted filaments but few dense-core vesicles (DCV) in normal pinealocytes. Tumoral pineal cells appeared to differentiate either towards a neurosensory pathway characterized by the presence of sensory cells elements (VCR and F), or towards a neuroendocrine pathway, with the occurrence of many DCV. Immunogold labeling demonstrated the presence of chromogranin A in neurosecretory granules.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 0942-0940
    Keywords: Carotid artery stenosis ; carotid artery endarterectomy ; carotid artery atheromatosis ; operative management ; outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary During 1978 to 1989, 235 patients were operated upon with 260 procedures for cervical carotid endarterectomy. The patients were classified according to the presence or absence of ischaemic symptomatology, and for symptomatic patients, according to the reversibility or persistance of ischaemic symptoms. So the selection of patients was: reversible ischaemia 46%, stroke 29%, asymptomatic patients 25%. In the stroke group, no patient was operated on as an emergency, the endarterectomy was only performed after stabilization of the clinical state. Three subgroups were included in patients operated on for asymptomatic carotid stenosis: casual discovery 40%, treatment of the second carotid artery (previous endarterectomy for symptomatic contralateral stenosis) 34%, and treatment of the second carotid artery (previous ECIC by-pass for contralateral carotid occlusion) 26%. All patients were operated upon after angiographic exploration (femoral catheterisation in most cases), and after cerebral CT scan. The surgical technique included general anaesthesia, systematic shunting, endarterectomy after longitudinal arteriotomy, closure without patch. The operating microscope has been used since 1985. The surgical results were studied in terms of uneventful postoperative course (87%), reversible complications (8%) and long lasting complications (5%). The long lasting complications were of local origin (1%), of neurological origin (2%), of general origin (1%). Overall the operative outcome at 6 months was: return to previous clinical state 95%, neurological sequelae 2%, death 3%. In the patients operated on for asymptomatic carotid stenosis the overall outcome was: previous clinical state 97%, death 3%. The legitimacy of carotid endarterectomy procedure is discussed in relation to some recent pertinent literature.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Existenz von zentrifugalen Bahnen, die im Bereich der Rezeptoren oder der Relais afferenter Bahnen endigen, ist seit langem bekannt (Cajal, Wallenberg,Brouwer), aber erst vor kurzem ist im Tierversuch gezeigt worden, daß die Reizung bestimmter corticaler Bezirke oder der mesencephalen Formatio reticularis die elektrischen Potentiale bahnt oder hemmt (je nach Versuchsbedingung), die mit der corticopedalen Leitung afferenter somästhetischer, visueller oder akustischer Signale verbunden sind. Eine solche Kontrolle konnte von einem von uns auch beim Menschen nachgewiesen werden.
    Abstract: Summary The existence of centrifugal pathways which terminate in the territory of the receptors or of the afferent relay pathways has long been known. But it has only recently been shown in animal experiments that the stimulation of definite cortical areas or of the mesencephalic reticular formation facilitates or inhibits (according to the conditions of the experiment) somaesthetic, visual and acoustic impulses destined for the cortex. According to the authors a similar mechanism could be demonstrated in man.
    Notes: Résumé L'existence de voies centrifuges se terminant au niveau des récepteurs ou des relais des voies afférentes est connue depuis longtemps (Cajal, Wallenherg, Brouwer), mais ce n'est que récemment qu'il a été demontré électrophysiologiquement, chez l'animal, que la stimulation de certaines aires corticales, ou de la formation réticulée mésencéphalique, pouvait faciliter ou inhiber (selon les conditions expérimentales) les potentiels électriques qui accompagnent la propagation corticipète de signaux afférents somesthésiques, visuels, acoustiques etc. Un tel contrôle a été mis en évidence par l'un de nous chez l'homme au niveau des voies géniculo-calcarines au cours d'exploration profonde du lobe occipital. Les résultats, que nous rapportons ici concernent les afférences somesthésiques ont été obtenues au cours de 3 interventions stéréotaxiques sur les noyaux de relais spécifiques thalamiques (V. P. L.-V. P. M.) chez des sujets conscients, non anesthésiés (atteints de douleurs irréductibles dûes à une névralgie post-zostérienne, de métastases pelviennes d'un cancer de la prostate, d'un cancer du larynx). Les réponses électriques thalamiques à des stimuli mécaniques (percussion rythmique de l'avant-bras ou de la face) ont été enrégistrées sur un appareil EEG. L'amplitude de ces réponses varie avec l'attention du sujet. Elle tend à augmenter si l'attention est dirigée sur le stimulus tactile. Par contre, elle diminue de façon significative si l'attention est dirigée sur une autre sphère sensorielle (calcul mental, attention auditive). En raison des conditions d'enregistrement, seuls les stimuli tactiles ont été explorés, à l'exclusion des stimuli nociceptifs. Ces résultats sont confrontés avec les données psychophysiologiques récentes concernant les mécanismes de l'attention. L'hypothèse de la mise en jeu d'un tel contrôle central lors de certains procédés analgésiques est soulevée (hypnose, accouchement sans douleur). Ces données permettraient également d'expliquer l'aspect particulier de certaines douleurs d'origine centrale (syndrome thalamique) qui doivent logiquement échapper à un tel contrôle.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 80 (1986), S. 90-92 
    ISSN: 0942-0940
    Keywords: Percutaneous lumbo-peritoneal shunt ; CSF rhinorrhoea ; pseudo tumour cerebri ; CSF shunt ; craniotomy ; syringomyelia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A population of 41 non-hydrocephalic patients in whom a lumboperitoneal shunt (LPS) was inserted for various conditions is reviewed. 19 had persistent cerebro-spinal fluid rhinorrhoea following cranial injury, basal skull surgery or of unknown origin, 3 had recalcitrant benign intra-cranial hypertension, 14 had a persistent bulging craniotomy site after operations for intra-cranial tumours or head trauma, 4 had syringomyelia and 1 had a postoperative cervical meningocele. There was no shunt-related mortality. LPS was effective in treating the initial symptomatology in 31 patients. Further revision or removal of LPS were needed on 9 occasions in 8 patients showing shunt-related mechanical or infectious complications or persistent postural headaches. This report demonstrates the safety of the LPS procedure experienced in another population of 146 patients with communicating hydrocephalus operated on in the meantime. According to the authors' experience, the versatility of the clinical applications of LPS seems well established. LPS should be considered when a CSF diversion is required in patients showing absent or minimal ventricular enlargement in the CT scan.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 0942-0940
    Keywords: Keywords: Chiari I malformation; magnetic resonance imaging; syringomyelia.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  The purpose of the present study is to evaluate retrospectively the effects of several intra-operative manipulations on the results of foramen magnum decompression (FMD) in patients having syringomyelia associated with type I Chiari malformation. Seventy-five patients having syringomyelia associated with Chiari I malformation were operated on between 1975 and 1996. This population was grouped into 4 subgroups according to the surgical protocol: group I=42 patients with FMD alone; group II=16 patients with FMD and third ventricle shunting; group III=9 patients with FMD and syringosubarachnoid shunting (SSS); group IV=8 patients with FMD and cerebellar tonsils resection. Pre- and postsurgical magnetic resonance imaging (MRI) studies were analyzed (and compared). Nine patients were lost to follow-up. The results were evaluated in the 66 remaining patients (mean follow-up: 52 months), using the Bidzinski's outcome scale (ref). Two patients (3%) died postoperatively, 31 (47%) had very good results (after additional surgery in 7), 16 (24,2%) had good results (after additional surgery in 7) and 17 (25,7%) had poor results despite further surgery in 9. A total of 27 reoperations were undertaken after primary FMD in 23 patients (35%). Thirty-nine patients (59%) had both pre- and postsurgical MRI evaluation. In 28 (72%) the syrinx had markedly decreased whereas it had remained stable in 11 (28%). Clinical results were not significantly different between the patients of groups I, II and III. Very good or good results were obtained in 24 patients (64,8%) of group I (after additional surgery in 10), in 8 (61,5%) of group II (after additional surgery in 1) and in 7 (87,5%) of group III (after additional surgery in 3). Results in group IV were as follows: 7 patients (87%) had very good results and one had a good result. With a mean follow-up of 28 months, no patient required additional surgery. Postsurgical MRI syrinx reduction was observed in all 8 patients either in the early postoperative course or on delayed follow-up. It is suggested that tonsils resection might enhance the results of FMD in individuals having Chiari I-related syringomyelia.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 12 (1996), S. 527-529 
    ISSN: 1433-0350
    Keywords: Children ; Oligodendroglioma ; Radiation therapy ; Chemotherapy ; Outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The cases of 15 children operated on for cerebral pure oligodendroglioma were studied. Two groups of children were distinguished. Group 1 children presented with epilepsy (7 cases); their tumor was histologically benign in all cases. These children are all alive after a median follow-up of 72 months; however, 2 of them presented with a local recurrence, which was operated on, and are actually disease-free. Group 2 children presented with intracranial hypertension (8 cases); the tumor was anaplastic in 7 cases. Despite postoperative radiotherapy and chemotherapy 6 children died; their median survival time was 17 months. The present series shows the existence of a clear correlation between clinical presentation, histological grading and survival in childhood cerebral oligodendrogliomas.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 4 (1988), S. 139-142 
    ISSN: 1433-0350
    Keywords: Choroid plexectomy ; Children ; Chronic infected hydrocephalus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Choroid plexectomy was performed for chronic infected hydrocephalus in 17 children via a direct open approach. In 16 cases, the CSF was sterilized soon after the plexectomy. In 37% of cases, the hydrocephalus was arrested without a shunt. The incidence of seizures did not increase after plexectomy. Removal of the choroid plexus was controlled by scintigraphy. Neuropsychological results were not encouraging, probably related to the long history of chronic ventricular infection. Surgical mortality was 6%. Choroid plexectomy should be considered as a possible treatment of chronic infected hydrocephalus in children.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1433-0350
    Keywords: Key words Hydrocephalus ; Shunts ; Shunt infection ; Valves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The rate of infectious complications following shunt implantations at the Pierre Wertheimer Hospital was 6.4% in 1992–1994. In order to improve this infection rate, new recommendations for surgery were applied and a new type of valve was used. The effects of these measures after a 1-year follow-up were analyzed in 70 patients. The rate of infection was zero, 2.8, and 4.3% at 2, 6, and 12 months, respectively. A case-control study did not reveal any significant risk factor among the patient and surgical factors analyzed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 4 (1988), S. 100-103 
    ISSN: 1433-0350
    Keywords: Brain tumors ; Infants ; Radical Surgery ; Oncologic treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seventy-six children were studied who had been operated on for intracranial tumors; they ranged in age from 0 to 2 years. Twenty-nine cases were under 1 year and 47 between 1 and 2 years of age. The outlook was relatively poor regarding the highly malignant tumors, but surprisingly encouraging in benign and low-grade malignant neoplasms. The undesirable effects of complementary oncological treatment in this age category are stressed. On the other hand the importance of radical surgery is emphasized as the best treatment for these lesions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 2 (1986), S. 55-59 
    ISSN: 1433-0350
    Keywords: Cerebellum ; Astrocytoma ; Childhood ; Surgery ; Results
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract According to CT appearance and surgical observations, cerebellar astrocytomas can be separated into three types. On CT scan, cystic astrocytomas have a typical mural nodule; with contrast injection only the nodule becomes hyperdense; the wall of the cyst is not modified. In these cases, only the mural nodule is removed since the wall does not contain tumor cells. In contrast, false cystic astrocytomas present an irregular wall, diffusely enhanced and thick. Then the wall is invaded by tumor cells, it must be totally removed. Solid astrocytomas may invade the peduncle, the IV ventricle, and the subarachnoid spaces. Removal is sometimes questionably total. As recurrences are not frequently observed in these cases, radiotherapy is not always recommended. Rather, radiotherapy is only used in cases of undoubted partial removal or after partial removal of a recurrence. Of 63 cases, early postoperative mortality was 4.7% and late recurrence 6.3%.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...