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  • 1
    Electronic Resource
    Electronic Resource
    Volume-CAD: An Integrated Environment for Virtual Manufacturing and Structural Analysis (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 23 (Oct. 2007), p. 17-24 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The Volume-CAD System Research Program aims at developing a core technology fordata integration of computerized design, analysis, manufacturing, and testing processes. Thepotential applications of the Volume-CAD environment cover a large area of engineering andbiomedical design. In this paper, we shall mainly focus on the VCAD-based software for thestructural analysis and the simulation of casting processes
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.23.17.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Comparison of five techniques for the cryopreservation of human polymorphonuclear cells
    Amsterdam : Elsevier
    Cryobiology 23 (1986), S. 556 
    Details
    ISSN: 0011-2240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0011-2240(86)90096-9
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  • 3
    Electronic Resource
    Electronic Resource
    Superoxide anion production by macrophages in streptozotocin-induced diabetic rats
    Amsterdam : Elsevier
    Free Radical Biology and Medicine 9 (1990), S. 145 
    Details
    ISSN: 0891-5849
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0891-5849(90)90692-C
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  • 4
    Electronic Resource
    Electronic Resource
    Endomorphins 1 and 2 Inhibit IL-10 and IL-12 Production and Innate Immune Functions, and Potentiate NF-κB DNA Binding in THP-1 Differentiated to Macrophage-Like Cells (2002)
    Oxford, UK : Blackwell Science Ltd
    Scandinavian journal of immunology 56 (2002), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We evaluated immunological effects of opioid peptides endomorphins 1 and 2 on the production of interleukin-10 (IL-10) and IL-12 cytokines, functions related to innate immunity and NF-κB DNA binding in human cell line THP-1. Endomorphins 1 and 2 inhibited lipopolysaccharide (LPS)-stimulated IL-10 and IL-12 production in THP-1 differentiated to macrophage-like cells by phorbol 12-myristate 13-acetate (PMA). Similarly, they suppressed LPS-stimulated IL-10 and IL-12 production in THP-1 matured to monocytes by 1α,25-dihydroxyvitamin D3. In addition, endomorphins 1 and 2 led to marked potentiation of NF-κB binding in THP-1 differentiated to macrophage-like cells. Furthermore, these endomorphins further potentiated LPS-induced NF-κB binding. Moreover, they inhibited chemotaxis, phagocytosis of Escherichia coli and PMA-stimulated production of hydrogen peroxide in THP-1 differentiated to macrophage-like cells. These results suggest that endomorphins 1 and 2 may inhibit THP-1 functions, such as cytokine production and functions related to innate immune, and potentiate NF-κB DNA binding in THP-1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.2002.01128.x
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  • 5
    Electronic Resource
    Electronic Resource
    Studies on saliva in ODU plaque-susceptible rats having experimental gingivitis (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 19 (1984), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Saliva was collected from the submandibular, parotid, and sublingual glands at to compare the amount of saliva between ODU plaque-susceptible (Sus) and plaque-resistant (Res) rats. The amount of saliva secreted was less in the Sus rats than in the Res rats. This difference was mainly due to a decrease in salivation from the submandibular glands, which resulted from the decrease in the weight of these glands. This reduction in salivation may be associated with the rapid rate of plaque formation seen around the mandibular teeth of these animals and the development of periodontal diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1984.tb01192.x
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  • 6
    Electronic Resource
    Electronic Resource
    Relationship between vitamin D receptor gene polymorphism and periodontitis (2002)
    Oxford, UK : Munksgaard International Publishers
    Journal of periodontal research 37 (2002), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Recent studies have shown that vitamin D receptor (VDR) gene polymorphism had regulatory effects on bone mineral density (BMD) and bone turnover. The VDR gene has also been indicated as a candidate gene for the susceptibility of osteoporosis. However, it is unclear whether VDR genotypes could be associated with alveolar bone loss of patients with periodontitis, or whether vitamin D receptor gene could be a candidate gene for susceptibility to periodontitis. The purpose of this study was to answer these two questions. Methods: Twenty-four cases of adult periodontitis (AP), 37 cases of early onset periodontitis (EOP) and 39 healthy controls were recruited for the study. Individual samples of venous blood and DNA were obtained from each subject. Genotypes of the TaqI VDR gene were determined by PCR and TaqI restriction endonuclease digestion. Results: One out of 24 AP patients, nine out of 37 EOP patients and two out of 39 healthy controls were detected with Tt genotype, while the rest had the TT genotype. The detected frequency of Tt genotype was significantly higher in EOP patients (24.3%) than in AP patients (4.2%) and healthy controls (5.1%). The frequency of t allele was also significantly higher in EOP patients. There was no statistical difference in the distribution of TaqI VDR genotypes between AP patients and healthy controls. The study suggests that Tt genotype might be a risk indicator for the susceptibility to EOP. Carriage of the allele (t) of the TaqI VDR gene may increase the risk of developing EOP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0765.2002.01605.x
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  • 7
    Electronic Resource
    Electronic Resource
    Bioactivity of CaO·SiO2 glasses added with various ions (1992)
    Springer
    Journal of materials science 3 (1992), S. 95-100 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The purpose of this investigation was to study the fundamental compositional dependence of bioactivity for bioactive glasses by adding a third component such as Na2O, B2O3, Al2O3, Fe2O3, P2O5 or F− to binary calcium silicate glass. Rectangular specimens of these six kinds of calcium silicate glasses containing each 3 wt ratio third component were implanted into the tibias of mature rabbits for 8 or 25 weeks. Contact microradiograms and SEM-EPMA showed that all glasses, except for Fe2O3-containing glass, formed a Ca, P-rich layer in combination with a Si-rich layer on their surfaces within 8 weeks. The other four kinds of glass except that containing Al2O3 became attached to bone through these layers within 8 weeks, and even Al2O3-containing glass became attached to bone by 25 weeks. Fe2O3-containing glass did not form these layers, nor did it attach to bone even at 25 weeks. A detachment test, performed 8 weeks after implantation, showed that only glasses containing B2O3, P2O5 and F− bonded tightly with bone. Glass containing B2O3 maintained a tight bond at 25 weeks, but the other two kinds of glass showed decreased loads at 25 weeks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705275
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  • 8
    Electronic Resource
    Electronic Resource
    Bioactivity of Fe2O3-containing CaO-SiO2 glasses: in vitro evaluation (1993)
    Springer
    Journal of materials science 4 (1993), S. 225-232 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: In order to reveal conditions for obtaining bioactive and ferrimagnetic glass-ceramics useful as thermoseeds for hyperthermia treatment of cancer, the effects of additives on the bioactivity of an Fe2O3-CaO-SiO2 glass were investigated by examining apatite formation on the surfaces of the glasses in a simulated body fluid with ion concentrations nearly equal to those in human blood plasma. A 3Fe2O3, 100CaO · SiO2 (in weight ratio) glass did not form an apatite layer on its surface in the fluid, but glasses of the same compositions with 3Na2O, B2O3 and/or P2O5 added (in weight ratio) formed an apatite layer. This indicates that bioactive and ferrimagnetic glass-ceramics could be obtained from Fe2O3-containing CaO-SiO2 glasses with Na2O, B2O3 and/or P2O5 added. Apatite formation on the surfaces of the glasses with the additives are interpreted in terms of the dissolution of the calcium and silicate ions from the glasses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00122273
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  • 9
    Electronic Resource
    Electronic Resource
    Bioactivity of CaO·SiO2-based glasses:in vitro evaluation (1990)
    Springer
    Journal of materials science 1 (1990), S. 239-244 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract In order to fundamentally study compositional dependence of bioactivity of glasses, both the surface structural changes of P2O5-free CaO · SiO2 glass due to exposure to a simulated body fluid and the effects of adding a third component, such as Na2O, MgO, B2O3, Fe2O3, P2O5 and CaF2, were investigated. An acellular aqueous solution which had almost equal ion concentrations to those of the human blood plasma was used as the simulated body fluid. The surface structure changes were examined by electronprobe X-ray microanalysis, thin-film X-ray diffraction (XRD) and Fourier transform infrared (FTIR) reflection spectroscopy. It was found that even P2O5-free CaO · SiO2 glass forms an apatite layer on its surface in the simulated body fluid, and that the rate of formation of the surface apatite layer is increased with the addition of Na2O and P2O5 while it decreased with the addition of MgO, B2O3, CaF2 and Fe2O3. This indicates that even P2O5-free CaO · SiO2 glass can bond to living bone, forming the surface apatite layer in the body and that its bioactivity is increased with the addition of Na2O and P2O5 while it is decreased with MgO, B2O3, CaF2 and Fe2O3. It is speculated that a glass of the composition CaO · SiO2 100, Fe2O3 3 in weight ratio does not bond to living bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00701083
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  • 10
    Electronic Resource
    Electronic Resource
    Healing of Segmental Ulnar Defects in Dog Using Bioresorbable Calcium Phosphate Cement Added with Recombinant Human Bone Morphogenetic Protein-2 (2000)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 192-195 (Sept. 2000), p. 833-836 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/45/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.192-195.833.pdf
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