Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Improved glucose tolerance four hours after taking guar with glucose (1980)
    Springer
    Diabetologia 19 (1980), S. 21-24 
    Details
    ISSN: 1432-0428
    Keywords: Dietary fibre ; guar ; glucose tolerance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To gain some insights about the possible cumulative metabolic effect after a high-fibre meal, 6 subjects took two 80 g oral glucose loads, 4 h apart. Addition of 22.3 g guar to the first load decreased the rise in blood glucose and insulin after the second (guar-free) load by 50% (p〈0.002) and 31% (p〈 0.02) respectively. This corresponded with decreased 3-hydroxybutyrate levels at the start of the glucose tolerance test after guar (by 20%, p〈0.02). When no guar was added to the first glucose load, both 3-hydroxybutyrate and non-esterified fatty acids tended to rise before the second test. No significant effect was seen in the responses of the gut hormones, gastric inhibitory peptide and enteroglucagon. Spreading the intake of the first 80 g of glucose over the initial 4 h (2 subjects) similarly flattened the glycaemic but increased the insulin response. The effect of guar on carbohydrate and fat metabolism, therefore, lasts at least 4 h and may result in improved carbohydrate tolerance to subsequent guar-free meals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00258305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The effect of glucose-dependent insulinotropic polypeptide infused at physiological concentrations on the release of insulin in man (1982)
    Springer
    Diabetologia 22 (1982), S. 33-36 
    Details
    ISSN: 1432-0428
    Keywords: Glucose-dependent insulinotropic polypeptide ; gastric inhibitory polypeptide (GIP) ; insulin ; blood glucose ; enteroinsular axis ; incretin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Blood glucose and the responses of insulin and glucose-dependent insulinotropic polypeptide (GIP) were measured in 12 healthy, normal weight subjects after drinking 50g glucose. On a subsequent occasion each subject was given a simultaneous infusion of GIP and glucose to mimic the plasma concentrations observed in the first test. The peak GIP concentration after oral glucose was 22.3±1.9pmol/l (mean±SEM), but was higher after GIP infusion at 36.3±4.6pmol/l, (p〈0.005). The blood glucose levels following oral glucose peaked at 6.3 ±0.5 mmol/l which'was the same as seen after intravenous glucose. The insulin response to oral glucose was, however, far higher (431.3±58.2pmol/l) than that obtained after GIP and glucose infusion (191.6 ±30.9 pmol/l, p〈0.001). Thus it has not proved possible to explain completely the oral enhancement of insulin release by the action of GIP alone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00253866
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Release of gastrointestinal hormones following an oral water load (1979)
    Springer
    Cellular and molecular life sciences 35 (1979), S. 1521-1523 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ingestion of 2 different water loads (7.5 and 15 ml/kg) by healthy subjects stimulated the release of plasma motilin, gastrin, pancreatic polypeptide and VIP. Atropine was found to block the release of PP but not the other hormones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01962823
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Disparity between glucose-dependent insulinotropic polypeptide and insulin responses in obese man (1983)
    Springer
    Diabetologia 25 (1983), S. 386-391 
    Details
    ISSN: 1432-0428
    Keywords: Glucose-dependent insulinotropic polypeptide ; insulin ; obesity ; glucose administration ; fat administration ; hypoglycaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Studies were carried out in 32 obese patients and 30 normal-weight control subjects to ascertain the response of glucose-dependent insulinotropic polypeptide (GIP) and insulin to (1) oral and intravenous glucose (10 obese and 10 control subjects), (2) oral fat and intravenous glucose (eight obese and six control subjects) and (3) mixed test meal (14 obese and 14 control subjects). Basal mean insulin was higher in the obese (99 pmol/l) than in the control group (40 pmol/l), but fasting blood glucose and GIP were not significantly different from normal. The total integrated response of insulin in obese subjects after oral glucose was 54.1 versus 33.3 nmol·l-1·h-1 in control subjects; glucose and GIP responses were similar in both groups. After intravenous glucose the integrated insulin response was 8.8 in the obese versus 5.0 nmol·l-1·h-1 in control subjects; GIP was unaffected by intravenous glucose and glucose levels were similar. Following oral fat and intravenous glucose, insulin secretion was again abnormal in the obese, 24.5 versus 7.3 nmol·l-1·h-1 in controls, but GIP responses were normal. However, the control subjects became hypoglycaemic after this test: blood glucose 2.8 mmol/l at 150 min compared with 4.6 mmol/l in the obese group. The insulin response to a mixed meal was also abnormal in obesity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00282515
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Colonic inhibition of gastric secretion in man (1981)
    Springer
    Digestive diseases and sciences 26 (1981), S. 195-201 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of colonic infusion of various solutions on submaximal pentagastrin-stimulated gastric secretion was determined in healthy volunteers. Hypertonic (823 mOsm/kg) glucose, mannitol, and saline, and also isotonic glucose significantly induced a marked and sustained inhibition of gastric acid secretion of 74%, 66%, 79%, and 54%, respectively. A similar degree of inhibition was obtained for pepsin secretion with hypertonic glucose and mannitol. Isotonic triglycerides and isotonic saline solutions had no significant effect on gastric acid secretion. Hypertonic glucose, mannitol, and saline infusions significantly increased plasma concentrations of enteroglucagon, whereas other solutions had no effect. No correlation, however, was found between the percentage rise of enteroglucagon and the percentage inhibition of gastric secretion obtained from any of the three hypertonic solutions. The physiological significance of these findings remains to be established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01391629
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...