Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Artikel: DFG Deutsche Nationallizenzen  (19)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Archiv der Mathematik 74 (2000), S. 129-147 
    ISSN: 1420-8938
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract. We prove that the solution operators ${\cal e}_t (\phi , \psi )$ for the nonlinear wave equations with supercritical nonlinearities are not Lipschitz mappings from a subset of the finite-energy space $(\dot {H}^1 \cap L_{\rho +1}) \times L_2$ to $\dot {H}^s_{q'}$ for $t\neq 0$ , and $0\leq s\leq 1,$ $(n+1)/(1/2-1/q')= 1$ . This is in contrast to the subcritical case, where the corresponding operators are Lipschitz mappings ([3], [6]). Here ${\cal e}_t(\phi , \psi )=u(\cdot , t)$ , where u is a solution of $$\left\{\matrix {\partial ^2_tu-\Delta _xu+ m^2u+|u|^{\rho -1}u=0, \, t〉0, \, x \in {\Bbb R}^n,\cr u\vert _{t=0}(x)=\phi (x),\hfill\cr \partial _tu\vert _{t=0}(x)=\psi (x). \hfill}\right.$$ where $n \geq 4, m\geq 0$ and $\rho 〉\rho ^\ast =(n+2)/(n-2)$ in the supercritical case.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    ISSN: 1432-1459
    Schlagwort(e): Ischaemic conduction block ; Small fibre function ; Thermal perception ; Resistance to ischaemia ; Mitochondrial encephalomyopathy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Thermal thresholds were measured during ischaemic compression block in the left forearms of 26 healthy subjects, 10 patients with diabetes mellitus and 6 patients suffering from different kinds of mitochondrial disorders. Cold and warm thresholds in the 6 patients with deficiencies in the respiratory chain increased earlier than in normals. When cold perception was impaired, cold stimuli were perceived as warmth and pinprick perception attenuated. In diabetics cold thresholds were less elevated during ischaemic block than in controls. This was paralleled by tingling paraesthesiae in all groups. The findings show that higher resistance to ischaemic nerve-fibre block in diabetes mellitus is not exclusively based on increased anaerobic metabolism.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    ISSN: 1433-044X
    Schlagwort(e): Key words Enchondroma • Pathological fracture • Autologous spongiosa ; Schlüsselwörter Enchondrome • Pathologische Fraktur • Autologe Spongiosa
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Enchondrome sind gutartige Knorpeltumoren, die am häufigsten an den Phalangen lokalisiert sind. In den Jahren 1982–1993 wurden an unserer Abteilung 73 Patienten mit monostotischen Enchondromen und 5 Patienten mit polyostotischen Enchondromen operiert. Die monostotischen Tumoren manifestierten sich durch pathologische Frakturen (38,4 %), durch Schmerzen oder Schwellungen; 11 % der Fälle waren Zufallsbefunde. Die Behandlung erfolgte standardisiert im Sinne einer Entfernung des Tumors und Füllung der Knochendefekthöhle durch autologe Spongiosa vom Beckenkamm, Ellenbogen oder von der Speiche. 3 Patienten (4,1 %) mußten wegen Wundinfektionen und Hämatombildung nachoperiert werden. Eine Patientin entwickelte eine Sudeck-Dystrophie. Bei einem Patienten (1,7 %) kam es zu einem Enchondromrezidiv. Unsere Nachuntersuchung von 65 Patienten zeigt, daß 77 % der Patienten mit monostotischen Enchondromen ein sehr gutes oder gutes funktionelles Langzeitresultat nach der Operation erreichen, aber nur 40 % der Patienten mit polyostotischen Enchondromen.
    Notizen: Summary Enchondroma are benign cartilaginous tumors and are localized most often at the site of the phalanges. Between 1982 and 1993 73 patients with monostotic enchondroma and 5 patients with polyostotic enchondroma were operated at our clinic. Clinical signs of monostotic tumors were pathological fracture (38.4 %), pain or swelling. Eleven percent of cases were accidental findings. Surgical treatment was performed by complete removal of the tumors and filling the bone cavity with autologous spongiosa taken from the pelvic bones, the elbow, or the radius. Three patients (4.1 %) had to be operated a second time due to wound infections and hematoma. In one case Sudeck's dystrophy was diagnosed. One patient (1.4 %) developed a recurrent tumor. Our follow-up examination of 65 patients showed that 77 % of the patients with monostotic enchondroma achieve very good or good functional long-term results after this operation, but only 40 % of the patients with polyostotic enchondroma.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Der Unfallchirurg 101 (1998), S. 184-192 
    ISSN: 1433-044X
    Schlagwort(e): Key words Amputation •“Mangeled extremity”• Upper extremity ; Schlüsselwörter Makroamputation • Kombinierte Knochen-Weichteil-Schädigung • Obere Extremität
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Zwischen 1982 und 1993 wurden 65 Patienten mit subtotaler und totaler Makroamputationsverletzung am Oberarm (n = 18), proximalen Unterarm (n = 32), sowie distalen Unterarm und Handgelenkbereich (n = 32) an unserer Klinik versorgt. Die primäre Einheilungsrate betrug 92,3 % (60/65). Eine frühe Reamputation war bei drei Patienten wegen nicht überwindbarer Gefäßprobleme (No-reflow-Phänomen, Gefäßverschluß), bei einem Patienten wegen lebensbedrohlichem Ischämie-Reperfusions-Syndrom und bei einem weiteren aufgrund septischer Streuung aus dem Replantat notwendig. Eine späte Reamputation auf Wunsch des Patienten war in keinem Fall notwendig. In einer retrospektiven Studie konnten 25 Patienten mit einem Nachuntersuchungszeitraum von mehr als 2 Jahren nachuntersucht und das „funktionelle Ergebnis“ nach der Klassifikation von Chen bewertet werden. Von acht Patienten mit einer inkompletten oder kompletten Makroamputation im Oberarmbereich zeigten 2 ein Grad-II-, 4 ein Grad-III- und 2 ein Grad-IV-Ergebnis. Nach Revaskularisation/Replantation (Rekonstruktion) im proximalen Unterarmbereich konnte bei 1 Patienten ein Grad-I-, bei 2 ein Grad-II- oder -III- und bei 5 ein Grad-IV-Ergebnis gefunden werden. In jeweils 2 Fällen lag nach subtotaler oder totaler Amputation im distalen Unterarm- und Handgelenkbereich ein Grad-I-, -II- oder -III-Ergebnis vor. In dieser Gruppe zeigte 1 Patient ein Grad-IV-Ergebnis. Addiert man die Grad-I–II-Ergebnisse, so ergibt sich eine „funktionelle Extremität“ im Oberarmbereich in 25 %, im proximalen Unterarmbereich in 30 % und im distalen Unterarm- und Handgelenkbereich in 58 % der eigenen nachuntersuchten Fälle. Der Vorteil der Revaskularisation/Replantation an der oberen Extremität besteht in der Rekonstruktion einer sensiblen (protektive Sensibilität zumindest in einem Teil der Hand) Extremität mit motorischer Teilfunktion (Greif-, Halte- und Stützfunktion), die jeder heute verfügbaren Prothese überlegen ist. Die höheren Kosten, größere Anzahl an notwendigen Operationen, längere postoperative Nachsorge und Arbeitsunfähigkeit nach Rekonstruktion verglichen mit der Amputation sind wegen der signifikant besseren durchschnittlichen Lebensqualität dieser Patienten gerechtfertigt.
    Notizen: Summary Between 1982 and 1993, 65 amputation and amputation-like injuries in the upper arm (n = 18), proximal and middle forearm (n = 32) and distal forearm and wrist level (n = 15) were treated in our institution. The overall survival rate in our series was 92.3 % (60/65). In 3 of 65 cases early secondary amputation because of vascular failure was necessary. There was one reamputation because of deep infection with beginning sepsis. Severe systemic disturbances were seen in one patient, requiring early reamputation. Twenty-five patients with a follow-up of more than 2 years were reviewed in a retrospective clinical study and evaluated according to the Chen classification. Of 8 patients with upper-arm involvement, 2 had a grade II result, 4 a grade III and 2 a grade IV result. There were 1 grade I, 2 grade II, 2 grade III and 5 grade IV results in the proximal forearm group. In the distal forearm group 2 patients each showed a grade I, II and III result and 1 a grade IV. Taking grades I and II results together, a “functional extremity” could be reconstructed at the upper arm level in 25 %, proximal forearm 30 %, and the distal forearm in 58 %. The main advantage of replantation/revascularization of the upper limb is the possibility of restoring some sensitivity to the hand in addition to partial motor recovery, which always provides twice as much individual motor function as is offered by any type of prosthesis currently available. The higher cost and number of operations needed, as well as the longer postoperative care and longer disability time after replantation/revascularization are nevertheless justified by the significant increase in quality of life.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    ISSN: 1432-2277
    Schlagwort(e): Key words Immunoadsorption ; Ig-Therasorb ; Hyperacute xenograft rejection ; Baboon ; Orthotopic xenotransplantation ; Xenoreactive antibodies
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To prevent hyperacute xenograft rejection (HXR) caused by preformed natural antibodies (XNAb) after orthotopic heart xenotransplantation (oXHTx) of landrace pig hearts into baboons, we used immunoadsorption of immunoglobulins IgG, IgM and IgA and complement with the reusable Ig-Therasorb column. In addition to functional data, tissue was sampled for histological, immunohistochemical and electron microscopical analysis. We performed three oXHTx of landrace pig hearts to baboons using extracorporeal circulation (ECC) connected to the immunoadsorption unit. Intraoperative treatment consisted of four cycles of immunoabsorption (IA). One oXHTx of a baboon without IA served as a control. A mismatch of donor and recipient heart size was prevented by selecting a 30–40 % lower body weight of donor pigs than recipients. Four cycles of IA removed more than 80 % of IgG, IgM and IgA, 86 % of anti-pig antibodies and 66 % of complement factors C3 and C4 from plasma. The graft of the control animal failed after 29 min. Orthotopic xenotransplantation with IA was selectively terminated after 100 min, 11 h and 21 h, respectively without any histological signs of HXR in light and electron microscopy. After weaning off from ECC these donor xenografts showed sufficient function with normal ECG and excellent cardiac output in echocardiography and invasive measurement (1.93 ± 0.035 l/min). The myocardium of the control xenograft demonstrated more deposits of Ig and complement components (C3, C4) than in the IA group. Baboons survive HXR after orthotopic pig heart xenotransplantation due to antibody depletion by reusable Ig-Therasorb column treatment. Long-term survival in an orthotopic baboon xenotransplantation model after IA, especially in combination with transgenic pig organs, could be a reliable preclinical trial for future clinical xenotransplantation programs.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 6
    ISSN: 1432-2277
    Schlagwort(e): Key words Ischemic time ; Hyperacute xenograft rejection ; Xenotransplantation ; Ig-Therasorb column ; Immunoadsorption
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract In xenotransplantation long ischemic time of grafts is supposed to have a marked influence on hyperacute rejection (HXR). We investigated the influence of different cold ischemic times on HXR of ex vivo “working pig hearts” perfused with human blood. Xenoreactive natural antibodies (XNAb) as a trigger of HXR were eliminated by Ig-Therasorb immunoadsorption (IA). Explanted Landrace pig hearts of group G1 and group G3 (with additional IA) underwent 4 h of cold ischemia prior to xenoperfusion. Control groups G2 and G4 (with IA) were kept ischemic for only 46.6 ± 15.8 and 51.2 ± 4.2 min, respectively. Ischemic time prolonged the perfusion time in our working heart model (G1: 356 ± 46.1 min; G2: 125 ± 31 min; P 〈 0.05). IA had no additional impact on perfusion time but was effective by itself. The heart weight increased fourfold more in G2 as compared to the other groups. IA without ischemia significantly improved cardiac output in G4 (G3: 198.8 ± 15.4 mL/min; G4: 338.5 ± 16.0 mL/min). Coronary flow in G2 was significantly lower than in G1 (G1: 157.9 ± 9.15 mL/min; G2: 59.4 ± 20.1 mL/min). Histological signs of HXR (light and electron microscopy) could be found in G2 in contrast to the other groups. Parameters of serological damage showed a minimum in G4 and the maximum in G2. In G1 XNAb were nearly equally eliminated immediately after the start of xenoperfusion as in IA groups G4 and G3. Four hours of ischemic time showed beneficial effects in preventing HXR, possibly caused by changes of the endothelial cell surface (for example, glycosylation or loss of α1–3Gal epitopes with a hapten effect).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Aesthetic plastic surgery 16 (1992), S. 325-330 
    ISSN: 1432-5241
    Schlagwort(e): Gynecomastia ; Mammoplasty ; Subcutaneous mastectomy ; Body contouring ; Male breast cancer
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract This article is a report on long-term followup of a total of 44 serious gynecomastia cases in the stages I–III (according to Deutinger). The treatment consisted of either a semicircular incision and subcutaneous mastectomy or a superiorly or an inferiorly based nipple transposition while performing male reduction mammoplasty. Aesthetically pleasing results could be obtained by a periareolar approach and mastectomy. This inconspicuous procedure is feasible even in massive gynecomastia cases (stage III) or in cases of male breast asymmetry. On the other hand, all cases with breast reduction plasty and nipple transposition resulted in wing-shaped, mainly broad scars, and subjectively unfavorable results. Consequently, we favor the semicircular approach in male reduction mammoplasty in treating serious gynecomastias. With regard to possible male breast cancer etiology, the histological specimen of the mammary gland in gynecomastia is excised prior to any additional liposuction for supplementary body contouring.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 8
    ISSN: 1618-2650
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 9
    Digitale Medien
    Digitale Medien
    Springer
    European journal of plastic surgery 10 (1987), S. 24-28 
    ISSN: 1435-0130
    Schlagwort(e): Pressure sores ; Sacral ; Ischial ; Trochanteric ; Myocutaneous flaps
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Thirty-three patients, mostly paraplegics, were treated for chronic pressure sores Campbell stages IV–VI overlying the sacrum, the ischial tuberosity and the femoral tuberosity. A stable, multi-layered cover of the defect, following excision of the decubiti, could be achieved in one stage using single myocutaneous gluteus maximus and biceps femoris island flaps or, when indicated, a combination of both. The postoperative complication rate was 7/65 (65 myocutaneous flaps were used in 33 patients) or 10.8%. Except for one recurrence due to a traumatic hematoma causing subtotal, external compression of the axial vascular pedicle and consequent partial necrosis of the myocutaneous island flap, all other flaps provided adequate closure and padding. They provided durable cover over a mean follow-up period of 25 months. These results are compared with the relevant literature.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Advances in contraception 12 (1996), S. 297-303 
    ISSN: 1573-7195
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...