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  • 1995-1999  (4)
  • 1980-1984  (3)
  • 1996  (4)
  • 1982  (3)
  • 1
    Digitale Medien
    Digitale Medien
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 104 (1996), S. 4198-4203 
    ISSN: 1089-7690
    Quelle: AIP Digital Archive
    Thema: Physik , Chemie und Pharmazie
    Notizen: The deuterated dicyanoquinonediimine salt Cu(2-CD3,5-CD3-DCNQI)2, (d6), a highly conductive organic metal, exhibits a phase transition from the metallic to the insulating state at Tc≈60 K. In a wide temperature range we observe an anticoincidence of high conductivity and electron spin resonance (ESR). These experiments were performed simultaneously in our ESR apparatus equipped for application of He pressure up to 200 bar. Near Tc there is a coexistence of conducting (ESR-silent) and insulating (ESR-detectable) domains. This correlation of ESR and conductivity σ points to a percolation limited conductivity. Upper and lower limits of the size of the domains are given. Light shifts Tc to lower temperatures, pressure to higher ones. This could be due to shrinking of the lattice which induces the phase transition when critical structural parameters are approached. This is most probably explained by a simultaneous development of a charge density wave (CDW) and a spin pairing within the DCNQI stack together with the trimerization of the lattice. Systematic measurements by variation of temperature, pressure, and light led to phase diagrams of (d6) and to the understanding of the mechanism of the phase transitions. © 1996 American Institute of Physics.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 47 (1982), S. 0 
    ISSN: 1750-3841
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Bush beans, kale and soybeans were used as models for studying the effects of processing by canning and freezing upon 51Cr and 65Zn content. Plants were grown hydroponically, intrinsically labeled with 51Cr and 65Zn, and processed either by canning or freezing. Freezing resulted in 65Zn losses of 10.7% for kale, 8.6% for bush beans, and 6.7% for soybeans. A loss of 3.8% of 51Cr resulted during freezing of bush beans. Canning resulted in 65Zn losses of 23% for kale, 19.7% for bush beans, and 28.8% for soybeans. Canned bush beans and kale contained 40.7% and 62.7% respectively, less 51Cr than unprocessed samples. Freezing resulted in a greater mineral retention than canning. Less opportunity for leaching is available in freezing and reduction in radionuclide content of the vegetables by canning was accounted for by transfer to the drained liquid.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 57 (1982), S. 275-281 
    ISSN: 1432-0533
    Schlagwort(e): Spinal cord ; Conus medullaris ; Mixed chemodectoma and ganglioneuroma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Report of a 33-year-old man with a yearlong historory of low-back pain radiating into the left leg. Neurologic examination upon admission tto the hospital revealed a spinal compression syndrome at the lovel L5. Laminectomy at L4/5 revealed an encapsulated intradural tumor measuring 4×2.5×2.5 cm. The tumor was attached to the dorsal root L4 and extended downward to the conus region. Light and electron microscopy revealed features mostly consistent with a mixed chemodectoma and ganglioneuroma.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    European journal of pediatrics 155 (1996), S. 74-76 
    ISSN: 1432-1076
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    ISSN: 1432-1076
    Schlagwort(e): Key words Haemophilus influenzae type b  ;   Combination vaccine  ;  Immunological memory
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  The lack of an adequate immune response to the major polysaccharide of the Haemophilus influenzae type b (Hib) capsule (polyribosyl ribitol phosphate) (PRP) in very young infants (〈 18 months) can be overcome by conjugating PRP to a T-cell dependent carrier protein. We studied whether administration of a tetanus-PRP conjugate vaccine reconstituted with a diphtheria-tetanus-acellular pertussis-hepatitis B (DTPa-HBV) vaccine as a three dose primary course at 3, 4 and 5 months of age induced PRP-specific immunological memory, by examining the anti-PRP response to a dose of unconjugated PRP given with the DTPa-HBV booster approximately 1 year later. The unconjugated PRP elicited protective anti-PRP antibody levels (≥ 0.15 μg/ml) in all but 3 of the 369 vaccinees, including 13 infants who failed to demonstrate a measurable immune response after the primary course. In a sub-cohort of 54 subjects all had anti-PRP levels ≥ 0.5 μg/ml within 7–14 days of the booster showing a rapid anamnestic type response. Both primary and booster responses were predominantly IgG1 indicating a T-cell dependent response. The DTPa-HBV components elicited protective anti-diphtheria, anti-tetanus and anti-HBs antibody levels in ≥ 98.5% of vaccinees, and immune responses to each of the acellular pertussis vaccine components in 92.3%–97.3% of subjects. Conclusion The tetanus-PRP conjugate vaccine not only elicited a good primary humoral response, but also induced immunological memory so that the infants were able to mount a large and rapid immune response to subsequent exposure to plain PRP, indicating that protection against circulating wild-type Hib had been generated. Successful induction of immunological memory occurred even when there was no measurable humoral anti-PRP response to the primary course. Tetanus-PRP conjugate vaccine can be used in combination with DTPa-HBV vaccine, when administered separately or as a single injection in the same syringe, in primary immunisation schedules at 3, 4 and 5 months of age.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 318 (1982), S. 288-294 
    ISSN: 1432-1912
    Schlagwort(e): Mianserin ; Clonidine ; Desipramine ; Acetylcholine ; α2-Adrenoceptors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The purpose of the present study was to characterize the effects of mianserin at α2-adrenoceptors. Firstly, the action of mianserin on postganglionic sympathetic fibres has been studied using the tachycardia induced by stimulation of the cardiac nerve in dogs. Mianserin increased this tachycardia, but could not prevent the inhibitory effect of clonidine in this model. However, an antagonistic effect of mianserin against clonidine was observed when animals were pretreated with desipramine. Secondly, mianserin antagonized the inhibitory effect of clonidine on the electrically stimulated guinea-pig ileum. In high concentrations, mianserin reduced both electrically and acetylcholine induced contractions. Thirdly, mianserin antagonised the sleep induced by clonidine in chickens. These results are consistent with α2-adrenoceptor blocking properties of mianserin in peripheral noradrenergic fibres in dogs, in cholinergic fibres in guinea-pig ileum and in the central nervous system in chickens.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1573-7373
    Schlagwort(e): astrocytic tumors ; gliomas ; malignancy classification ; computer aided grading ; TESTAST 268 ; histologic morphometry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Forty three cases of astrocytic tumors and mixed gliomas were studied with the aim of evaluating the reproducibility of the Kernohan grading system vis a vis (a) grading using computer-aided malignancy classifier TESTAST 268 and (b) grading by quantitative morphometric evaluation of the various histological parameters of TESTAST 268. These patients were then followed up for variable periods with a maximum of forty months. High inter and intra-observer variability were observed in the Kernohan grading system. TESTAST 268 was found to be simpler, rapid and more reproducible. However, one drawback observed of this system was that it did not completely eliminate inter-observer variability because there was still some subjectivity in assignment of the categorical values against the histological features. Morphometric evaluation of the semiquantitative assignment values of the 4 histological variables in the TESTAST 268 classifier using Zeiss Morphomat-30 revealed a statistically significant difference between the clusters of the measured quantitative values. A repeat grading using TESTAST 268 and categorical assignment values of histological features derived from the absolute values obtained by morphometry resulted in complete elimination of inter-observer variability. Thus, this study highlights the importance of objectivisation using TESTAST 268 and histologic morphometry in the grading of gliomas. However, since this is a preliminary study on a small number of cases, no cut off values of these measurements have been proposed.
    Materialart: Digitale Medien
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