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  • 2000-2004  (3)
  • 1990-1994  (6)
  • 1960-1964
  • 1955-1959
  • 2002  (3)
  • 1992  (6)
  • 1
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Regulation of acute-phase serum amyloid A (A-SAA) synthesis by proinflammatory cytokines and steroid hormones in human aortic smooth muscle cells (HASMCs) is distinct from that in HepG2 cells. To study the cis- and trans-activating promoter element involved in the SAA1 gene expression by HASMCs and HepG2 cells, we constructed plasmid vectors for luciferase reporter gene assay with varying lengths of SAA1 upstream regulatory region (up to 1431 bp), and examined their response to proinflammatory cytokines and/or steroid hormones. The corresponding vectors with the SAA4 upstream regulatory region served as controls. The presence of proposed transcriptional regulatory factors binding to these regions was confirmed immunohistochemically.The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5′-flanking regions were determined, respectively. SAA1 promoter transcription in cultured HASMCs was upregulated not by proinflammatory cytokines, but rather by glucocorticoids. This differed from HepG2 cells, in which SAA1 promoter transcription was upregulated synergistically by proinflammatory cytokines and glucocorticoids. The promoter activity of a series of truncated SAA1 promoter constructs measured using the reporter gene assay showed that the 5′-region from −252 to −175, containing a consensus site for CCAAT/enhancer binding proteins α,β (C/EBPα,β), was essential for SAA1 induction in HASMCs. In HepG2 cells, the 5′-region from −119 to −79, containing a nuclear factor kappa-B (NFκB) consensus sequence, was essential for the induction. The functional significance of the C/EBP site as indicated by the immunohistochemical result was that in HASMCs anti-C/EBPβ reactivity was shifted from the cytoplasm to the nuclei.We have, therefore, demonstrated that the region containing the C/EBPα,β consensus binding site between the bases −252 and −175 is important for the glucocorticoid-induced SAA1 gene expression in HASMCs but not in HepG2 cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 19 (1992), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report the clinical, histological and ultrastructural features of juvenile colloid milium affecting a brother and sister. In this rare condition, translucent papules develop on sun-exposed areas of skin, with onset in childhood. Histologically and ultrastructurally, the papules consist of amyloid-like material derived from epidermal keratonocytes. A review of the literature suggests a possible genetic abnormality that leads to sun-induced degeneration of keratinocytes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 147 (2002), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Exercise-induced anaphylaxis (EIA) is a form of physical urticaria that is induced by exercise. A 16-year-old Japanese boy had a 4-year history of recurrent wealing and dyspnoea after physical exercise such as jogging, playing handball or riding a bicycle in winter. The episodes were not associated with ingestion of foods including wheat or soya bean. A provocation test, with 15 min of exercise and 2 min of cold stimulation immediately before or immediately after the exercise, elicited a weal that was localized to the test area. A challenge test with ingestion of boiled soya beans and exercise did not elicit a weal. Therefore, in this case, cold exposure, but not food ingestion, was essential for inducing EIA. Cold-dependent EIA is different from cold urticaria, food-dependent EIA, cholinergic urticaria and cold-induced cholinergic urticaria, and may be a distinct entity.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract Powder catalysts were prepared by immersion of amorphous Ni-40Zr and Ni-40Ti alloys containing a few at % of platinum group elements in HF solution. This treatment led to preferential dissolution of the valve metal and nickel with a consequent formation of microcrystalline alloy powders consisting of concentrated platinum group elements and some nickel and valve metal. Porous gas-diffusion electrodes prepared by using these alloy catalyst powders were employed for electrochemical reduction of oxygen and oxidation of hydrogen in 1 M H2SO4 at 25°C. The activity of the electrodes prepared from the amorphous alloys containing Pt−Ru, Pt−Rh, Pt and Pd for oxygen reduction was considerably higher than that of the platinum black electrode. Oxidation of hydrogen occurred readily close to the equilibrium potential. Amorphous alloy electrodes containing Pt−Ru, Pt−Rh and Pt were more active than the platinum black electrode for the hydrogen oxidation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 389-393 (Apr. 2002), p. 165-170 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1437-1596
    Keywords: Polymorphism FXIIIB ; Population genetics ; Bloodstains ; Polymorphismus FXIIIB ; Populationsgenetik ; Blutspuren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Der Polymorphismus des FXIIIB wurde bei 555 unverwandten Japanern mit Hilfe der isoelektrischen Fokussierung und anschließendem Immunoblotting untersucht. Fünf allgemein vorkommende Phänotypen und die seltene Variante FXIIIB 15-3 wurden beobachtet. Die Allel-Frequenzen waren FXIIIB = 0,3063, FXIIIB2 = 0,0162, FXIIIB3 = 0,6766 und FXIIIB15 = 0,0009. Die Bestimmung der Phänotypen war auch an Blutspuren mit folgenden Lagerungsbedingungen möglich: Bei 37°C über einen Zeitraum bis zu 4 Monate, bei Raumtemperatur und bei 4°C länger als 6 Monate. Das FXIIIB-System kann einen neuen, aussagekräftigen genetischen Marker für gerichtsmedizinische Blutspurenuntersuchungen darstellen.
    Notes: Summary The polymorphism of FXIIIB was investigated in 555 unrelated Japanese individuals using isoelectric focusing and immunoblotting. Five common phenotypes and a rare variant type FXIIIB 15-3 were observed. The allele frequencies were FXIIIB*1 = 0.3063, FXIIIB*2 = 0.0162, FXIIIB*3 = 0.6766 and FXIIIB*15 = 0.0009. Phenotyping was also possible from bloodstains stored at 37°C for up to 4 months and from bloodstains stored at room temperature and at 4°C for over 6 months. The FXIIIB system can provide a new powerful genetic marker for the medicolegal grouping of bloodstains.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 355 (1992), S. 624-626 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The MoO3 amorphous film was prepared by vacuum evaporation of high-purity MoO3 powders (99.9%) onto a l-mm-thick NESA glass substrate (5 x 2.5 cm), with a typical film thickness of -l,OOOnm being obtained. Photochromic experiments were done in air, and a 500-W high-pressure mercury lamp was ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 270 (1992), S. 249-258 
    ISSN: 1435-1536
    Keywords: Viscoelasticity ; spinnability ; tetradecyltrimethylammoniumsalicylate ; hexadecyltrimethylammoniumsalicylate ; rodlikemicelle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The viscoelasticity has been measured for aqueous solutions of tetradecyl-and hexadecyltrimethylammonium salicylates (C14TASal, C16TASal). The aqueous solutions of C14TASal without salt displayed the gel-like behavior at 10.0×10−2 g cm−3, but those more dilute than 3.2×10−2 g cm−3 presented the viscoelasticity similar to that of a Maxwell liquid. The Maxwell-like behavior was converted to the polymer-like one on the addition of (0.1–0.2) M NaBr or (0.02–0.2) M NaSal. The gel-like viscoelasticity can be connected with the spinnability of “cohesive fracture failure”, and the Maxwell-like and polymer-like viscoelasticities are concerned with the spinnability of “ductile failure”. The gel-like and Maxwell-like viscoelasticities originate in the pseudo-network formed by the pseudo-linkages between rodlike micelles, while the polymer-like viscoelasticity is caused by the entanglement of long rodlike micelles in semidilute and concentrated solutions. The aqueous solutions of C16TASal behaved very similar to those of C14TASal.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 13 (1992), S. 211-221 
    ISSN: 1572-9567
    Keywords: corresponding states ; high temperatures ; mixing rule ; shock-tube method ; thermal conductivity ; xenon-helium mixtures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The thermal conductivity of gases at high temperatures has been measured by the shock-tube method, which is uniquely suited to measure thermal conductivities of gases at high temperatures above 2000 K. A consistent set of thermal-conductivity data over a wide range of temperatures has been obtained from optimum combinations of shock-tube experiments at high temperatures, previously published data at lower temperatures, and a theoretical correlation of the temperature dependence. In the present study, the thermal conductivity of xenon-helium mixtures has been determined at compositions of 10 and 30 mol% xenon over the temperature range from 300 to 4800 K. Even though there is a large difference between the thermal conductivity of pure xenon and that of helium, it is interesting that the dependences of the thermal conductivity of the mixture on temperature and composition are linear. The experimental results are in good agreement with the predicted values based on the corresponding-states principle and the mixing rule. From these experimental results, interpolating the corresponding-states correlation data, we represent the equation of xenon-helium gas mixtures for thermal conductivity in terms of temperature and composition.
    Type of Medium: Electronic Resource
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