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  • 1
    Electronic Resource
    Electronic Resource
    9β-Lanostane-Type Triterpene Lactones from the Stem Bark of Abies veitchii (1991)
    s.l. : American Chemical Society
    Journal of natural products 54 (1991), S. 1337-1344 
    Details
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/np50077a017
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  • 2
    Electronic Resource
    Electronic Resource
    Interaction of hydrophobically modified hydroxyethyl cellulose with various added surfactants (1992)
    s.l. : American Chemical Society
    Macromolecules 25 (1992), S. 1304-1310 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00030a016
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  • 3
    Electronic Resource
    Electronic Resource
    The long-term growth rate of residual acoustic neurinomas (1994)
    Springer
    Acta neurochirurgica 129 (1994), S. 127-130 
    Details
    ISSN: 0942-0940
    Keywords: Acoustic neurinoma ; computed tomography ; growthrate ; intracapsular removal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The growth rate of 19 residual acoustic neurinomas was examined in a long-term follow-up study (median, 10 years; range, 5 to 17 years) following intracapsular removal. Of these, 10 (53%) had regrowth, three (16%) showed regression, and six (32%) were unchanged. The 10 acoustic neurinomas showing regrowth were divided into two categories, either solid or cystic, according to computed tomographic findings. Five acoustic neurinomas with cyst formation showed rapid regrowth, with the tumour doubling time ranging from 0.15 to 5.0 years (median, 4.5 years), and required re-operation. Five solid tumours showed slow regrowth, with the tumour doubling time ranging from 9 to 34 years (median, 15 years). Although cyst formation is a major factor in rapid regrowth, residual acoustic neurinomas without cyst formation have a slower growth potential. In this study, 74% of the residual acoustic neurinomas have never required re-operation. It is advisable to choose intracapsular removal if there is major risk of neurological deficits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01406491
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  • 4
    Electronic Resource
    Electronic Resource
    Anomaly of venous system in congenital occipital dermal sinus (1994)
    Springer
    Acta neurochirurgica 128 (1994), S. 174-179 
    Details
    ISSN: 0942-0940
    Keywords: Congenital occipital dermal sinus ; dural sinuses ; development ; embryology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report two cases of congenital occipital dermal sinus in which elongation of the vein of Galen, elevation of the straight sinus, division of the superior sagittal sinus, elevation of the confluence of sinuses, elevation of transverse sinus and narrowing of the torcular angle were observed in the venous phase of cerebral angiography. Enhanced computed tomography (CT) revealed enlargement of the supracerebellar cistern, elevation of the straight sinus and of the confluence of sinuses, but no evidence of intracranial lesions. In order to study the relationship between anomalies in the dural venous sinuses and congenital occipital dermal sinus, we examined both cases from an embryological viewpoint.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400671
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  • 5
    Electronic Resource
    Electronic Resource
    Prognosis of intracranial germ cell tumours: Effectiveness of chemotherapy with cisplatin and etoposide (CDDP and VP-16) (1993)
    Springer
    Acta neurochirurgica 120 (1993), S. 111-117 
    Details
    ISSN: 0942-0940
    Keywords: Germ cell tumour ; chemotherapy ; CDDP ; VP-16
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A co-operative study for patients with intracranial germ cell tumours was performed to analyze their prognosis and the effectiveness of Cisplatin/Etoposide (CDDP/VP-16) chemotherapy. A total of 46 patients; 30 primary and 16 recurrent cases were registered from 15 participating neurosurgical institutions in Japan. Based on histological criteria and tumour markers, they were classified into three groups; germinoma, germinoma with syncytiotro-phoblastic giant cell (STGC), and non-germinomatous malignant tumour. Sixteen patients were treated with CDDP/VP-16 chemotherapy alone and the other 30 patients were treated by a combination of surgery and/or radiation in addition to chemotherapy. Eleven out of 13 patients (85%) with germinoma showed a complete (n=10) or partial (n=1) response to CDDP/VP-16 chemotherapy even if their tumours were recurrent and there was evidence of CSF dissemination. For the germinoma with STGC and non-germinomatous malignant tumour, a high response rate; 100% for the former and 78% for the latter, could also be achieved in both the primary and the recurrent cases except in those cases of immature teratoma. Their survival times were still different between them. Two-year survival was 50% in germinoma with STGC and 48% in non-germinoma, while it was 88% in germinoma cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02112027
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  • 6
    Electronic Resource
    Electronic Resource
    Cerebral haemodynamic changes after endovascular treatment of arteriovenous malformations: Evaluation by single-photon emission CT (1994)
    Springer
    Acta neurochirurgica 127 (1994), S. 142-150 
    Details
    ISSN: 0942-0940
    Keywords: Arteriovenous malformation ; endovascular treatment ; cerebral haemodynamic changes ; single-photon emission CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebral haemodynamic changes in 17 patients with cerebral arteriovenous malformations (AVMs), who showed hypoperfusion on single-photon emission computed tomography (SPECT) before endovascular treatment, were studied after embolization. Nine of them had non-haemorrhagic clinical manifestations and the other eight had a history of intracranial haemorrhage. Obliteration of AVMs was nearly total in six patients and partial in eleven. New low density lesions on X-ray computed tomography (CT) developed in 3 of 6 patients after nearly total obliteration and one of 11 patients after partial obliteration. The first SPECT after embolization showed diminished hypoperfusion in 11 of 13 patients without new low density lesions and one of 4 patients with new low density lesions. Diminution of hypoperfusion was seen even in two patients who underwent SPECT study immediately after the embolization. Cerebral circulation was improved in five of eight patients with low density lesions before embolization and in nine of eleven patients after partial obliteration. Hypoperfused state in the haemorrhagic group tended to remain unchanged compared with that in the non-haemorrhagic group. The hypoperfused area was expanded after embolization in three patients with new cerebral infarction. It is important for improvement of cerebral circulation to reduce the shunt flow without causing new infarction due to the embolization itself. In one of two patients who had a hyperperfused area surrounding the AVM after embolization, an unexpected and abnormal degree of brain swelling and haemorrhage occurred at the end of the surgery 20 days after the embolization. In the other patient, total extirpation was successfully performed after confirming disappearance of hyperperfusion in the follow-up SPECT. SPECT allows repeated measurement of the cerebral blood flow pattern easily and safely, and is useful for AVM management.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808757
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  • 7
    Electronic Resource
    Electronic Resource
    Structure of (R)-tetrahydro-2-furancarboxylic acid monohydrate (1990)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 46 (1990), S. 106-108 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270189004877
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  • 8
    Electronic Resource
    Electronic Resource
    A hydrate of the sodium salt of a penem carboxylic acid (1994)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 1254-1256 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270194002532
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  • 9
    Electronic Resource
    Electronic Resource
    The differences in human spinal motoneuron excitability during the foreperiod of a motor task (1990)
    Springer
    Experimental brain research 79 (1990), S. 357-364 
    Details
    ISSN: 1432-1106
    Keywords: Movement preparation ; Ankle dorsiflexion ; Ankle plantar flexion ; H-reflex ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Changes in excitability of the spinal motoneuron pool during the foreperiod, which was fixed at 0.8 s, in simple and choice reaction time experiments using ankle dorsiflexion and plantar flexion were studied in fourteen healthy normal subjects by combining the visually guided tracking and H-reflex testing methods. Almost all cases showed a significant facilitation in the soleus H-reflex within the time interval between 100 and 300 ms after a warning signal (Phase I), irrespective of movement direction and task modality. The pretibial H-reflex was also facilitated. On the other hand, variable effects were noted in the later half of the foreperiod, particularly within the 200 ms prior to the response signal (Phase II). Using a simple reaction task with dorsiflexion, six cases showed no changes in the soleus H-reflex, while four others showed statistically significant inhibitory changes and the remaining four showed facilitation. The inhibition and facilitation were often accompanied with very weak and unintended EMG activities in the pretibial and Sol muscles respectively. A similar finding was obtained in the simple plantar flexion task and the choice reaction task with dorsiflexion or plantar flexion. We suggest that the facilitation at Phase I represents a perceptual orienting response to a warning signal and the effects seen in Phase II represent the difference in the waiting attitude of each subject anticipating initiation of the coming task, or the preparatory “set” which primed the spinal motor structure in a biased position.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00608245
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  • 10
    Electronic Resource
    Electronic Resource
    Symptomatic cerebrospinal fluid dissemination of cerebral glioblastoma (1990)
    Springer
    Neuroradiology 32 (1990), S. 146-150 
    Details
    ISSN: 1432-1920
    Keywords: CT ; Glioblastoma ; Seeding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Computed tomography (CT) findings in eleven patients with symptomatic cerebrospinal fluid (CSF) dissemination from cerebral glioblastoma were analyzed and, in seven cases subsequently autopsied, they were compared with histological observations. Each patient had multiple CT abnormalities including periventricular enhancement (5/11), subarachnoid enhancement (10/11) and progressive hydrocephalus (7/9) by cranial CT, and small filling defects with or without block (5/5) by CT myelography. The areas that showed periventricular or subarachnoid enhancement on CT were confirmed to have macroscopically detectable seeding at autopsy. On the other hand, microscopic deposits were more widely distributed than the enhancement suggested, and were hardly visualized on CT. In association with subarachnoid seeding, we found low-density lesions on CT which had resulted from ischemia or reinvasion of adjacent structures by disseminated glioblastoma and resulting parenchymal edema. By cranial CT, subarachnoid enhancement seems to be a very reliable sign of CSF seeding, whereas periventricular enhancement due to CSF metastases should be carefully distinguished from that due to periventricular tumor infiltration. CT myelography is capable of revealing minute metastatic spinal deposits and may be helpful for ruling out spinal seeding as well as its precise evaluation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588565
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