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  • 1
    Electronic Resource
    Electronic Resource
    Rust Layers Formed on Weathering Steels by Long-Term Atmospheric Exposure to Industrial and Coastal Environments (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 127 (Sept. 2007), p. 203-208 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Rusts formed on several types of weathering steels and a plain carbon steel exposed toenvironments for a long term were investigated by EPMA, XRD and TEM/ED. Information aboutdistribution of elements, type of rusts, depth distribution of rusts, and their relation with type ofsteels and environments are made clear
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/24/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.127.203.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Partial ornithine transcarbamylase deficiency in females: diagnosis by an immunohistochemical method (1987)
    Springer
    European journal of pediatrics 146 (1987), S. 370-372 
    Details
    ISSN: 1432-1076
    Keywords: Ornithine transcarbamylase deficiency ; Heterozygote ; Immunohistochemical analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Females heterozygous for the X-linked urea cycle disorder, ornithine transcarbamylase (OTC) deficiency have a significant risk of developing hyperammonaemia. Diagnosis of this genetic defect in a proband is the essential starting point for family studies. By an immunohistochemical analysis of the liver specimens fixed in 10% formalin, we confirmed heterozygous status for OTC deficiency in two female patients, a 15-year-old girl and a 2-year-old girl, who died of hyperammonaemia. Since most affected males lack cross reactive materials (CRM), an immunochemical analysis should be useful for the diagnosis of most heterozygous females.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444940
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  • 3
    Electronic Resource
    Electronic Resource
    Development of Cup-Cast Method; Semi-Solid Slurry Preparation without External Stirring Force (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 116-117 (Oct. 2006), p. 358-361 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Semi-Solid metal (SSM) processing is now considered a commercially successfulmanufacturing route producing millions of near net shape parts per annum for the automotiveindustry. Although semi-solid process is currently widely used as a manufacturing process whichproduces near net-shape metal component, the processes those used for the preparation ofsemi-solid slurry still take a great deal of time, energy and money. Cup cast method – recentlydeveloped by the authors – is able to make semi-solid slurry preparation as easy as pouring waterfrom a pitcher into drinking glass. In this method globular solid particles are prepared by controllingthe turbulence and heat distribution in the melt through pouring instead of applying certain externalstirring forces, in other common method. In the current study, cup cast method applied to Al-A356alloy using simple cylinder. Vital factors of this method were optimized by investigatingmicro-structures
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/22/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.116-117.358.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Analytical Model for Heat Transfer Phenomena in Cup-Cast Method (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 116-117 (Oct. 2006), p. 569-572 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Cup-cast method is a new method deals with semi-solid slurry preparation recentlydeveloped by the authors. In this method, suspension of globular solid particles in molten metal isprepared by controlling the nucleation and growth of solid-particles through the simplest andquickest techniques. In this method, heat transfer phenomenon plays an important role in governingthe shape, size, and fraction of solid particles. In the current study, a heat transfer model wasproposed and applied to Al-A356 alloy semi-solid slurry preparation. The heat transfer model wasbased on heat balance consideration between cup and slurry and it was in a good agreement withexperimental results
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/22/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.116-117.569.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    Lymphomatous polyposis of the gastrointestinal tract, including mantle cell lymphoma, follicular lymphoma and mucosa-associated lymphoid tissue lymphoma (2005)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 47 (2005), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  Lymphomatous polyposis (LP) is considered to represent mantle cell lymphoma (MCL) of the gastrointestinal (GI) tract. However, a few reports have suggested that some are follicular lymphoma (FL) or mucosa-associated lymphoid tissue (MALT) lymphomas. In this study, we analysed 35 patients and clarified the clinicopathological features of LP.Methods and results:  Paraffin-embedded tissue samples were stained immunohistochemically and analysed by tissue-fluorescence in situ hybridization (T-FISH) for IGH/CCND1 (cyclin D1) and IGH/BCL2. The average age of the patients was 58.3 years. Over half of the cases showed gastric, duodenal, small intestinal, ileocaecal and sigmoid colonic lesions (15, 19, 15, 16 and 16 cases, respectively). Phenotypically, cases were classified into three types of MCL (cyclin D1+ CD5+ CD10–) (n = 12), FL (cyclin D1– CD5– CD10+) (n = 14) and MALT (cyclin D1– CD5– CD10–) (n = 9). T-FISH identified 11 of the 11 examined cases with MCLs to have IGH/CCND1, while seven of 10 cases with FL had IGH/BCL2, and none of the MALT cases were positive for IGH/CCND1 or IGH/BCL2. At the study endpoint, five of 12 patients with MCL were dead, two of 14 with FL and one of nine with MALT were dead of other disease. Event-free survival analysis showed significantly poorest outcome in MCL, followed by FL, while MALT was associated with a favourable outcome (P = 0.0040).Conclusions:  Our study emphasizes the importance of differentiating MCL, FL and MALT of LP in evaluating prognosis and hence the most suitable therapeutic regimen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2005.02225.x
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  • 6
    Electronic Resource
    Electronic Resource
    Micropapillary pattern: a distinct pathological marker to subclassify tumours with a significantly poor prognosis within small peripheral lung adenocarcinoma (≤20 mm) with mixed bronchioloalveolar and invasive subtypes (Noguchi's type C tumours) (2005)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 46 (2005), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  A micropapillary pattern (MPP) in lung adenocarcinoma, characterized by papillary structures with epithelial tufts lacking a central fibrovascular core, has been reported to be a new pathological marker of poor prognosis. However, its clinicopathological and prognostic significance in small lung adenocarcinomas (≤20 mm) remains undetermined. A new histological classification of small lung adenocarcinoma proposed by Noguchi et al. has been found to be useful since it has defined surgically curable bronchioloalveolar carcinoma (BAC)-type tumours (Noguchi's type A and B) based on the absence of active fibroblastic proliferation. However, BAC-type tumours with active fibroblastic proliferation (Noguchi's type C), which is adenocarcinoma with mixed subtypes including BAC and invasive carcinoma in the new World Health Organization (WHO) classification, account for most of the small adenocarcinomas and represent a heterogeneous group ranging from minimal to overtly invasive cancer with variable prognoses. Therefore, in this study the aim was to investigate whether MPP can be an additional histological marker(s) to subclassify this heterogeneous group in small lung adenocarcinoma.Methods and results:  One hundred and twenty-two cases of small lung adenocarcinomas (≤20 mm in maximum dimension) classified according to the new WHO classification and Noguchi's proposal were analysed with reference to the presence of MPP. Of the 122 cases, 67 (55%) were MPP-positive and 55 (45%) were MPP-negative. Lymph node metastasis and pleural invasion were significantly more frequent in the MPP-positive group: 74% and 66% in the positive group versus 26% and 34% in the negative group, respectively. The 5-year survival of the MPP-positive group was 54%, whereas that of the MPP-negative group was 81% (P = 0.024). The 5-year survival rates of BAC (Noguchi's type A and B) (n =14), mixed BAC and invasive adenocarcinoma (Noguchi's type C) (n = 85) and invasive adenocarcinoma (Noguchi's type D and F) (n = 23) were 100%, 68% and 36%, respectively. In patients with mixed BAC and invasive adenocarcinoma (Noguchi's type C tumours), the 5-year survival of the MPP-positive group (n = 51) was 54%, significantly lower than that of the MPP-negative group (n = 23) of 100% (P = 0.02).Conclusions:  MPP is a simple and distinct pathological marker to subclassify tumours with a significantly poor prognosis within small (≤20 mm) mixed BAC and invasive adenocarcinoma (Noguchi's type C tumours).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2005.02126.x
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  • 7
    Electronic Resource
    Electronic Resource
    Clinicopathological features of cutaneous lesions of adult T-cell leukaemia/ lymphoma (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Adult T-cell leukaemia/lymphoma (ATLL) is a human malignancy associated with human T-cell leukaemia virus type I (HTLV-I). ATLL frequently involves the skin.Objectives  To correlate the clinicopathological features and prognosis in patients with ATLL and cutaneous lesions.Methods  We examined the HTLV-I proviral state and the clinicopathological features of the cutaneous lesions in 80 patients with serum anti-ATL antibody, to clarify the correlation between macroscopic/histopathological findings and prognosis. Southern blot analysis was performed in all cases to detect monoclonal HTLV-I proviral DNA integration.Results  The cutaneous lesions of 46 patients were positive for proviral DNA integration. The median survival time of patients with monoclonal proviral DNA integration in cutaneous lesions was 14 months, which was markedly shorter than that of patients negative for proviral DNA integration (72 months). Of the 46 patients with proviral DNA, 21 had solitary or multiple red nodules (including three with subcutaneous induration), eight had multiple red papules and 17 had erythema. Patients with papules and nodules had poorer prognosis than those with erythema. Histopathologically, the prognosis was poorer in patients with nodular or diffuse infiltration of medium-sized to large lymphoma cells, compared with those with perivascular infiltration of small to medium-sized lymphoma cells.Conclusions  Our results show a close correlation between clinicopathological features of HTLV-I-associated cutaneous lesions and prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06274.x
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  • 8
    Electronic Resource
    Electronic Resource
    Bonding mechanism between silicon carbide and thin foils of reactive metals (1985)
    Springer
    Journal of materials science 20 (1985), S. 3976-3982 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Pressureless-sintered SiC pieces and SiC single crystals were joined with foils of reactive metals at 1500° C (1773 K) for titanium and zirconium foils or at 1000° C (1273 K) for Al/Ti/Al foils. Bend testing at various temperatures up to 1400° C (1673 K), optical and electron microscopy, and electron-probe X-ray microanalysis studies were carried out on the specimens. From the results, it was concluded that the fairly high bond strength of titanium-foil joined SiC specimens might be attributed to the formation of a Ti3SiC2 compound, since good lattice matching between SiC and Ti3SiC2 was obtained in the SiC single crystals. Also in the Al/Ti/Al-foil joined SiC, high bond strength was obtained, but it decreased steeply at 600° C (873 K) because of a retained aluminium phase. The bond strength in the zirconium-foil joined SiC was low.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00552387
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  • 9
    Electronic Resource
    Electronic Resource
    Time relationship between ambient temperature change and antigen stimulation on immune responses of mice (1989)
    Springer
    International journal of biometeorology 33 (1989), S. 19-23 
    Details
    ISSN: 1432-1254
    Keywords: Temperature change ; Immune response ; Male mice ; Corticosterone ; Physiological adaptation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract We investigated the time relationship between ambient temperature change and antigen stimulation on immune responses to sheep red blood cells (SRBC) and polyvinylpyrrolidone (PVP) in mice. In the case of a shift from comfortable (25°C) to cold (8°C) temperatures, suppression in the number of splenic plaque-forming cells (PFC) took place mainly when the shift was done between 1 day before and 2 to 4 days after immunization. The suppression of the PVP response lasted for up to a maximum of 6 days when mice were transferred 1 day before immunization. In the case of a temperature shift from 25° to 36.5°C, the suppressive effect was found when the temperature shift was done between 4 days before and 2 days after immunization. The effect lasted longer than that of the temperature shift to cold, i.e., at least 9 days after the temperature shift. Blood corticosterone levels after the temperature shifts corresponded to changes in the immune responses: elevation of the blood corticosterone levels was observed for only the first 3 days after a temperature shift to 8°C but for 10 days after a temperature shift to 36.5°C during the period time of the experiment. These result suggested that blood corticosterone level contributes to the duration of the effects of temperature shifts on immune responses of mice. Furthermore, it appeared that the early stage of the immune response is more susceptible to temperature shifts than the later stage. To explain these results, the terms “effective period” in the course of physiological adaptation to changed ambient temperature and “susceptible period” in the course of the immune response, were proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01045892
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  • 10
    Electronic Resource
    Electronic Resource
    The effects of the light-dark cycle and its inversion on the susceptibility of mice to lead acetate (1987)
    Springer
    International journal of biometeorology 31 (1987), S. 95-107 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The effects of the light-dark (LD) cycle and its inversion on the susceptibility of mice to lead were investigated. Groups of mice were injected once with a high (200 mg Pb/kg body weight) or low (10 mg Pb/kg body weight) dose of lead acetate at one of four-hourly intervals, i.e., 09.00 h, 13.00 h, 17.00 h, 21.00 h, 01.00h, and 05.00 h, on the days before and after a phase shift in the LD cycle. The main indices used to measure the susceptibility of the mice were dying rate and percent mortality of ICR mice following injection together with the Pb concentration (Pb-B) and δ-aminolevulinic acid dehydratase (ALAD) activity in the blood. In the present study, we ascertained the following facts: (1) Dying rate (time to death following injection) and Pb-B exhibited a circadian rhythm with a peak initiated by injection in the dark period. (2) Injection with a low dose of lead within a few days after an LD inversion significantly decreased the level of ALAD activity and increased the Pb in the blood in comparison with control animals kept under a non-inverted LD cycle. Both the dying rate and the percent mortality following a high dose of lead, however, were hardly affected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02202929
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