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  • 1
    Electronic Resource
    Electronic Resource
    Anaphylactoid reactions and histamine release do not occur after application of the opioid tramadol (1987)
    Springer
    Inflammation research 20 (1987), S. 310-313 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract After an i.v. application of 100 mg tramadol in 13 healthy volunteers (1) no change in plasma histamine concentration could be detected, (2) systemic anaphylactoid reactions did not occur, (3) cutaneous reactions were not rated as anaphylactoid since itching and erythema were seen only once after tramadol whereas erythema was also observed twice after saline, (4) blood pressure and heart rate were only very slightly and transiently elevated without any abnormalities in ECG-readings and (5) only side effects typical for opioid therapy were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02074699
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  • 2
    Electronic Resource
    Electronic Resource
    Technik der „Kontinenten Proktocolektomie”: Totale Colektomie, Proktomucosektomie, ileo-anale Anastomose mit vorgeschaltetem Ileumreservoir (1987)
    Springer
    Langenbeck's archives of surgery 371 (1987), S. 161-174 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01251907
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  • 3
    Electronic Resource
    Electronic Resource
    279. Die chirurgische Therapie der familiären Adenomatosis coli Proktocolektomie ohne permanentes Ileostoma (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 695-695 
    Details
    ISSN: 1435-2451
    Keywords: Adenomatosis coli ; Proctocolectomy ; Mucosal proctectomy ; Ileoanal anastomosis ; Adenomatosis coli ; Proktocolektomie ; Proktomucosektomie ; Ileo-anale Anastomose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei der familiaren Adenomatosis coli ist wegen des lichen Carcinom-Risikos bei meist jugendlichen Patienten die Indikation zur totalen Proktocolektomie gegeben. Nach kurzem Überblick fiber die Diagnostik zeigt der Film die operative Technik der totalen Colektomie mit Proktomucosektomie, Anlage eines S-fbrmigen Ileumreservoirs, Bowie anschließender ileo-analer Anastomose. Ein passageres, protektives Ileostoma wurde zusdtzlich in allen Fallen angelegt. Das Verfahren wurde seit 1981 bei 12 Patienten angewandt (11 Adenomatosis coli, 1 Colitis ulcerosa). Eine postoperative Letalität trat nicht auf. Über postoperative Frühkomplikationen wird berichtet.
    Notes: Summary Due to the high risk of malignancy in familial adenomatosis coli in mostly young patients, a total proctocolectomy is necessary. After a few remarks about diagnostic procedures, the film shows the operative technique of total colectomy, mucosal proctectomy, formation of an ileal S-pouch, followed by ileoanal anastomosis. A temporary protective ileostomy was carried out in all cases. As of 1981, 12 patients have undergone this operation (11 adenomatosis coli, 1 ulcerative colitis) with no postoperative mortality. The possibility of early postoperative complications is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836877
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  • 4
    Electronic Resource
    Electronic Resource
    CARS spectroscopy of molecules and clusters in supersonic jets (1988)
    Springer
    Applied physics 45 (1988), S. 205-214 
    Details
    ISSN: 1432-0649
    Keywords: 42.65 ; 33.20.Fb ; 36.40.+d ; 34.50.Ez
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Supersonic molecular beams of D2, CH4, NH3, and C2H4 are investigated in the expansion region employing collinear coherent anti-Stokes Raman spectroscopy (CARS). The analysis of rotationally resolved CARS spectra allows the determination of temperatures in the beam. The rotational relaxation as a function of stagnation pressure and separation from the nozzle is studied by recording theQ branch for D2 and the ν3 R andS branches for CH4. Rotational temperatures for NH3 are determined by investigating the complete ν3 band. At strong stagnation conditions broad structures arise which can be attributed to the formation of NH3 clusters. For C2H4 the ν5 band with resolved rotational structure is reported. Again, at larger distances from the nozzle, broad structures are observed. They are assigned to the ν1 and ν5 vibrations in the C2H4 cluster.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687148
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  • 5
    Electronic Resource
    Electronic Resource
    Reliability and practicability of the fluorometric-fluoroenzymatic histamine determination in pathogenetic studies on peptic ulcer: Detection limits and problems with specificity (1987)
    Springer
    Inflammation research 21 (1987), S. 1-25 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Histamine, among various “biologic-physiologic” abnormalities, is considered as a pathogenetic factor in chronic duodenal ulcer disease. The 10–30 per cent difference between its concentration in gastric and duodenal mucosa of patients compared to healthy controls, however, has to be demonstrated to be specific for the disease. It has to be shown to be neither a methodological artefact nor a common effect, concomitant factor or consequence. This study, after a series of pathogenetic trials examines systematic errors (biases) in the fluorometric-fluoroenzymatic histamine assay under the conditions of field studies including tests on specificity over a time period of 10 years. It concentrates on sensitivity (detection limits) and specificity of a standard technique described herein. A modified Shore procedure for large scale assays in human biopsies was developed including reference luminescence values for all reagents, cleaning material and glassware, reduction of OPD concentration to 0.05%, purification ofn-heptan, omission of centrifugation steps in the extraction procedure and use of 2 ml 1M HClO4 in the homogenization step to prevent losses of histamine due to adherence to the mechanical homogenizer. This assay was sensitive enough to measure histamine without difficulty in any biopsy taken. The detection limit was 3 ng/biopsy, but the smallest quantities of the amine ever obtained were 10.6 and 18.3 ng/biopsy (depending on both histamine content and biopsy weight). A series of problems had to be solved both in achieving and demonstrating specificity. It had to be defined not only for the assay in general, but also for assessing the difference in histamine content between ulcer patients and healthy controls. Exogenous more than endogenous fluorescing material interfering with the determination had to be excluded. A series of pitfalls were detected which had to be overcome in demonstrating the specificity of the assay by physicochemical and enzymatic tests. The specificity of the identification tests was more often impaired than the histmine assay itself. Fluorescing material interfering with the assay occurred in the homogenization, extraction and condensation steps, was found in water, OPD, the organic solvents, the cleaning material and in all kinds of plastic vessels. Plasticizers were shown by physicochemical characteristics including fluorescence spectra to be most likely responsible for this interfering material. Rules were developed to exclude such hazards in specificity in longterm pathobiochemical studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01974915
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  • 6
    Electronic Resource
    Electronic Resource
    Measurement of the 4f strong interaction level width in light antiprotonic atoms (1986)
    Springer
    The European physical journal 325 (1986), S. 261-265 
    Details
    ISSN: 1434-601X
    Keywords: 36.10.Gv ; 13.75.Cs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The yields of the atomic 4→3 transitions in antiprotonic14N,16,17,18O,19F, and23Na were measured at the CERN antiproton facility, LEAR. From these, the widths Γup of the 4f levels were determined to be 136±19meV (14N); 603±22 meV (16O); 731±35 meV (17O); 795±23 meV (18O); 2.79±0.16 eV (19F); and 23.8±7.4 eV (23Na).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01294606
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  • 7
    Electronic Resource
    Electronic Resource
    16. Die instrumentelle Oesophagusperforation — ihre Behandlung und Ergebnisse (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 131-133 
    Details
    ISSN: 1435-2451
    Keywords: Endoscopy ; Oesophagus perforation ; Mediastinitis ; Oesophagostoma ; Endoskopie ; Oesophagusperforation ; Mediastinitis ; Oesophagostoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die instrumentelle iatrogene Oesophagusperforation steht in der Ursachenhäufigkeit an vorderster Stelle der endoskopischen Eingriffe, die in neuerer Zeit immer mehr an Bedeutung gewonnen haben. Vom 1. 1. 73 bis 31. 12. 84 sahen wir in Mannheim 46 Oesophagusperforationen. Der jüngste Patient war ein 2jähriges Mädchen mit einer benignen Stenose, der älteste ein 89jähriger Mann mit einem Kardia-Ca. Der Altersdurchschnitt betrug 62 Jahre. 26 Patienten wurden konservativ behandelt und 20 Patienten mußten operiert werden. In 2 Fällen war eine Diskontinuitäts-Operation erforderlich. In 1 Fall erfolgte die Rekonstruktion 6 Monate später erfolgreich. 9 Patienten verstarben. In jedem Fall war die Todesursache kardio-pulmonales Versagen bei septischem Geschehen.
    Notes: Summary The number of oesophagus perforations has increased considerably with the increase in endoscopic, diagnostic and therapeutic procedures. 46 instrumental oesophagus perforations have been observed between 1973 and 1984. The youngest patient was a 2-year-old girl with a benign oesophagus stenosis and the eldest was an 89-year-old man with a neoplasm of the cardia. The average age was 62 years. 26 patients were treated conservatively; 20 patients were treated surgically. In 2 cases the oesophagus was diverted at the cervical level and the cardia detached. 8 months later this was successfully reconstructed. 9 out of 43 patients died. In every case, the cause of death were cardio-pulmonal complications accompanying general sepsis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836616
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  • 8
    Electronic Resource
    Electronic Resource
    91. Erfahrungen mit der ileoanalen Anastomose und Ileum-Pouch-Bildung nach Colektomie und Proktomucosektomie (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 477-480 
    Details
    ISSN: 1435-2451
    Keywords: Adenomatosis coli ; Ulcerative colitis ; Mucosal proctectomy ; Ileo-anal anastomosis ; Adenomatosis coli ; Colitis ulcerosa ; Proktomucosektomie ; Ileoanale Anastomose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1981 wurden 12 Patienten (11 Adenomatosis coli=AC/1 Colitis ulcerosa-CU) durch Colektomie u. Proktomucosektomie mit ileo-analer Anastomose (IA) u. S-förmiger Ileumpouch-Bildung (IP) operiert. 7 Männer und 5 Frauen hatten ein Durchschnittsalter von 33 Jahren (21–46 J.). Die Operation erfolgte synchron abdomino-peranal. Die Rückverlegung des protektiven Ileostoma erfolgte durchschnittlich nach 4,6 Mo. (11/12). Postoperative Komplikationen konnten beherrscht werden (IA-Insuffizienz =4, Sacralabsceß= 1, Stenose=3, Ileus und Re-Laparotomie =2). Spätergebnisse: Spontanentleerung 11/11, Kontinenz 10/11, Stuhlfrequenz 6–8/die Das Op.-Verfahren scheint für die AC und CU geeignet.
    Notes: Summary Since 1981 12 patients (II adenomatosis coli=AC/1 ulcerative colitis =CU) had a colectomy and mucosal proctectomy with ileo-anal anastomosis (IA) and formation of an ileal-S-pouch (IP). The mean age of 7 men and 5 women was 33 years (21–46 yrs). We preferred the synchronous abdomino-peranal operation. Protective ileostomy was closed after a mean of 4.6 months in 11 patients. Postoperative complications: IA-in sufficiency =4, sacral abscess =1, stenosis=3, ileus and reoperation=2). Late results: spontaneous defecation: 11/11, continence 10/11, evacuation 6–8/day. This operative procedure seems to be good for AC and CU.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836690
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  • 9
    Electronic Resource
    Electronic Resource
    73. Die kontinente Proktocolektomie —Erschwernis durch Voroperationen (1987)
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 421-423 
    Details
    ISSN: 1435-2451
    Keywords: Adenomatosis coli ; Colitis ulcerosa ; Proctocolectomy ; Ileo-anal pouch anastomosis ; Adenomatosis coli ; Colitis ulcerosa ; Proktocolektomie ; Ileo-anale Reservoiranastomose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1981 wurden 23 Patienten (19 Patienten mit Adenomatosis coli, 4 Patienten mit Colitis ulcerosa) kontinenzerhaltend proktocolektomiert: die Methode bestand in einer totalen Colektomie, Proktomucosektomie, ileo-analer Anastomose unter Vorschaltung eines S-Reservoirs und Anlage einer passageren Ileostomie. Bei 3 Patienten wurde der Eingriff durch vorausgegangene Operationen erschwert bzw. verunmöglicht. Die kritischen Punkte bezüglich des Operationsverfahrens, vor allem in Hinblick auf vorher erforderliche Eingriffe, werden erläutert. Postoperative Komplikationen und funktionelle Ereignisse werden dargestellt.
    Notes: Summary Since 1981 23 Patients (19 with adenomatosis coli, 4 with colitis ulcerosa) underwent proctocolectomy with preservation of continence: total colectomy, proctomucosectomy, ileo-anal anastomosis with formation of an ileal S-pouch, and protective loop ileostomy. In 3 patients previous operations caused difficulties in performing the procedure. Critical points of the operative technique are explained, with special regard to the possibility of previous surgery. Postoperative complications and functional results are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297857
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  • 10
    Electronic Resource
    Electronic Resource
    The synthesis and solution properties of some rigid-chain, water-soluble polymers: Poly[N,N′-(sulfo-phenylene)phthalamide]s and poly[N,N′-(sulfo-p-phenylene)pyromellitimide] (1989)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 27 (1989), S. 3745-3757 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Poly[N,N′-(sulfo-phenylene)phthalamid]es and poly[N,N′-(sulfo-p-phenylene)pyromellitimide] were prepared in water-soluble form and were found to have unique solution properties, similar in some respects to xanthan. The polymer most investigated, poly[N,N′-(sulfo-p-phenylene)terephthalamide] (PPT-S), is produced as the dimethylacetamide (DMAC) salt by the solution polymerization of 2,5-diaminobenzenesulfonic acid with terephthaloyl chloride in DMAC containing LiCl. The isolated polymer requires heating in water to dissolve; the resulting cooled solutions are viscous or gels at concentrations as low as 0.4%. They are highly birefringent, exhibit circular dichroism properties, and are viscosity-sensitive to salt. Solutions of this polymer mixed with those of guar or hydroxyethyl cellulose give significantly enhanced viscosity. The polymer is relatively low molecular weight, ca. 5000 estimated from viscosity data. Some meta and para isomeric analogs of PPT-S were prepared; these polymers have similar properties except they are more soluble in water, and higher concentrations are required to obtain significant viscosity. Poly[N,N′-(sulfo-p-phenylene) pyromellitimide] (PIM-S) was prepared similarly from 2,5-diaminobenzenesulfonic acid and pyromellitic dianhydride. Its aqueous solution properties are similar to those of PPT-S. It appears that these relatively low-molecular-weight rigid-chain polymers associate in water to form a network that results in viscous solutions at low concentrations.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1989.080271115
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