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  • 1
    Electronic Resource
    Electronic Resource
    Blood viscosity in young male diabetics with and without retinopathy (1980)
    Springer
    Diabetologia 18 (1980), S. 359-363 
    Details
    ISSN: 1432-0428
    Keywords: Retinopathy ; insulin treated diabetes ; blood viscosity ; plasma viscosity ; haematocrit ; fibrinogen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Blood viscosity (shear rates 100s-1 and 0.94 s-1) and several of its major determinants (haematocrit, plasma fibrinogen and plasma viscosity) have been measured in 38 male insulin-treated diabetics, aged 18–50 years, and in 38 non-diabetic control subjects matched for age and smoking habit. Diabetics without fundoscopic retinopathy (n=20) had higher mean blood viscosity than controls at the high shear rate (7.07 cP vs 6.75 cP, p〈0.05) and the low shear rate (21.2 cP vs 18.7 cP, p〈0.025). These differences persisted after correction of blood viscosity to a standard haematocrit, and were associated with increased plasma viscosity (1.41 cP vs 1.34 cP, p〈0.025) and plasma fibrinogen (2.9 g/L vs. 2.5 g/L, p〈0.025). Diabetics with retinopathy (n=18) had higher mean blood viscosity than diabetics without retinopathy at the high shear rate (7.53 cP vs 7.07 cP, p〈0.05) and the low shear rate (24.3 cP vs. 21.2 cP, p〈0.05), associated with a higher haematocrit (p〈0.05). Blood viscosity and haematocrit correlated with the duration of diabetes (r〉0.32, p〈0.05).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00276814
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  • 2
    Electronic Resource
    Electronic Resource
    Diabetes in adolescence (1981)
    Springer
    Diabetologia 20 (1981), S. 517-523 
    Details
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions The adolescent diabetic has a totally different set of problems from either the child or adult with diabetes. Failure to recognise this and deal with it will result in non-compliance and non-attendance at the clinic. Anyone taking on the care of a teenage diabetic must be prepared to try to resolve all their problems in the one clinic. There is nothing worse for the youngster than to be rendered artificially schizophrenic when she has to attend the dietician for advice on weight reduction, a family planning clinic for advice on contraception, a psychiatrist to find out how to resolve family problems etc. It has been said that when dealing with the interplay between diabetes and psychological factors in the diabetic adolescent, “the well rounded clinician who can treat the disease and the emotional decompensation that accompanies it, is indeed the flower of our profession” [38].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252758
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  • 3
    Electronic Resource
    Electronic Resource
    A phenylbutazone dose-finding study in rheumatoid arthritis (1983)
    Springer
    European journal of clinical pharmacology 24 (1983), S. 773-776 
    Details
    ISSN: 1432-1041
    Keywords: phenylbutazone ; rheumatoid arthritis ; dose ; oxyphenbutazone ; side effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Different doses of phenylbutazone have been compared in a double blind study on 32 patients with rheumatoid arthritis in order to determine the minimum effective dose. Of 8 different dose levels studied (90 mg, 150 mg, 180 mg, 240 mg, 270 mg, 300 mg, 360 mg and 450 mg/day) the most efficacious was found to be 300 mg/day. Doses below this did not produce full benefit; no further improvement occurs with higher doses. Although 7/32 patients developed adverse reactions there was no relationship between these and the plasma levels of either phenylbutazone or oxyphenbutazone. An attempt was made to distinguish ‘responders’ from ‘non-responders’. We found no relationship between response and plasma levels of phenylbutazone or oxyphenbutazone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00607086
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  • 4
    Electronic Resource
    Electronic Resource
    A pharmacological and clinical comparison of prednisolone and betamethasone in rheumatoid arthritis (1982)
    Springer
    European journal of clinical pharmacology 23 (1982), S. 321-325 
    Details
    ISSN: 1432-1041
    Keywords: prednisolone ; betamethasone ; rheumatoid arthritis ; adrenal suppression ; chronic dosage ; anti-inflammatory activities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary 1. Two oral corticosteroids, prednisolone (8 mg/day) and betamethasone (1 mg/day) have been compared in terms of efficacy and adrenal suppressive activity when used in chronic oral dosage in rheumatoid arthritis. 2. 20 patients were entered to a single blind crossover study receiving each drug for a two-week period. Clinical and laboratory assessments were performed. 3. At this dosage there was no significant difference between any of the clinical parameters assessed for either drug though patient preference was 13 for prednisolone and 7 for betamethasone. 4. At this dosage adrenal suppression was not equivalent, being significantly more marked with betamethasone. 5. The results suggest that prednisolone is the drug of choice for chronic dosage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00613613
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  • 5
    Electronic Resource
    Electronic Resource
    Bain, David: Actors and Audience: A Study of Asides and Related Conventions in Greek Drama : Oxford, Oxford University Press, 1977 (1981)
    Cambridge : Cambridge University Press
    The @classical review 31 (1981), S. 8-9 
    Details
    ISSN: 0009-840X
    Source: Cambridge Journals Digital Archives
    Topics: Classical Studies
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0009840X00236317
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  • 6
    Electronic Resource
    Electronic Resource
    JAMES T. KERNOHAN AN APPRECIATION (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 36 (1981), S. 0 
    Details
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2494.1981.tb01562.x
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  • 7
    Electronic Resource
    Electronic Resource
    The Eunuchus: Terence and Menander (1983)
    Cambridge : Cambridge University Press
    The @classical quarterly 33 (1983), S. 428-444 
    Details
    ISSN: 0009-8388
    Source: Cambridge Journals Digital Archives
    Topics: Classical Studies
    Notes: A vast amount has been written on the relationship between Terence's and Menander's Eunuchus. On some points a good measure of agreement has been reached, but much remains in dispute. In an important article W. Ludwig convincingly demonstrated the inner unity of Terence's plot, against earlier theories of large-scale ‘contaminatio’ The nature of the changes made by Terence in introducing two characters from Menander's Colax (30–3) is now fairly clear, although argument is possible over details. The changes are numerous but relatively small and do not affect the main lines of Menander's plot. In this paper I shall argue that Terence made similar changes in two other parts of the play, and that these caused certain anomalies which have prompted theories of more drastic Terentian change.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0009838800034698
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  • 8
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    Terentian Originality in the 'Phormio' and 'Hecyra' (1983)
    Wiesbaden, etc. : Periodicals Archive Online (PAO)
    Hermes. 111 (1983) 431 
    Details
    ISSN: 0018-0777
    Topics: Classical Studies
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:5443-1983-111-00-000018
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  • 9
    Electronic Resource
    Electronic Resource
    Partial deficiency of hypoxanthine-guanine phosphoribosyltransferase with reduced affinity for PP-ribose-P in four related males with gout (1984)
    Springer
    Human genetics 〈Berlin〉 67 (1984), S. 18-22 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A family is described in which four affected males, spanning two generations, have hyperuricemia and gout accompanied by hematuria but are without severe neurologic involvement. The affected males were found to have markedly reduced levels of erythrocytic hypoxanthine-guanine phosphoribosyltransferase (HGPRT) activity; these were 5–12% with hypoxanthine and 0.5–3% with guanine as compared to controls. Erythrocytic adenine phosphoribosyltransferase (APRT) was approximately three-fold elevated in the affected individuals. The residual HGPRT activity in affected males enabled characterization of some of the properties of this mutation. The apparent Michaelis constants (km) for both hypoxanthine and guanine were essentially unchanged, whereas the km for PP-ribose-P was approximately 10–20-fold elevated for all four affected males. The enzyme was more sensitive to product inhibition by IMP and GMP than controls, and exhibited greater thermal lability at 65°C than found with control lysates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00270552
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  • 10
    Electronic Resource
    Electronic Resource
    Lateglacial and early Flandrian chronology of the Isle of Mull, Scotland (1982)
    [s.l.] : Nature Publishing Group
    Nature 296 (1982), S. 558-561 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Four sites have been investigated (Fig. 1). Loch an t-Suidhe (grid ref. NM370215, altitude 30 m OD) on the Ross of Mull and Mishnish (grid ref. NM455565, altitude 120 m OD) to the west of Tobermory are infilled basins which lie outside the area affected by Loch Lomond Stadial ice, and contain a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/296558a0
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