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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 91 (2002), S. 5411-5418 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have successfully fabricated superconducting nanobridges and grain-boundary junctions from epitaxial YBa2Cu3O7−δ thin films with thickness between 20 and 30 nm and width down to ∼100 nm. The patterning process turned out to severely deteriorate the transport properties resulting in structural damage, corrosion, and oxygen loss. The most crucial steps are the baking procedure used to cure the electron beam resist, the resist development, and the ion beam etching process. By optimizing these steps and applying a suitable post-treatment procedure a significant enhancement of the sample quality could be achieved. An ultraviolet light assisted oxygenation procedure after the patterning process enabled us to achieve superconducting transition temperatures between 80 and 87 K and critical current densities at 4.2 K up to 4×107 A cm−2 for the nanobridges and 5×103–2×105 A cm−2 for the grain boundary junctions. At 4.2 K junctions with width down to 100 nm corresponding to a junction area down to 2.3×10−3 μm2 showed superconductivity. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 78 (2001), S. 1095-1097 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We performed numerical simulations and experiments on Josephson vortex flow transistors based on parallel arrays of YBa2Cu3O7–δ grain boundary junctions with a cross gate line allowing us to operate the same devices in two different modes named the Josephson fluxon transistor (JFT) and Josephson fluxon–antifluxon transistor (JFAT). The simulations yield a general expression for the current gain versus number of junctions and normalized loop inductance and predict higher current gain for the JFAT. The experiments are in good agreement with simulations and show improved coupling between gate line and junctions for the JFAT as compared to the JFT. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 79 (2001), S. 3654-3656 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report on the preparation and characterization of the double-perovskite compound Sr2CrWO6 with a Curie temperature of 390 K. We have fabricated both Sr2CrWO6 bulk sintered polycrystalline bars and high-quality epitaxial thin films on SrTiO3 substrates by pulsed-laser deposition. The samples were characterized by thermogravimetric analysis, x-ray diffraction, electrical transport, and magnetization measurements. Polycrystalline samples containing a large number of grain boundaries show a large low-field magnetoresistance of up to 100% at 5 K. At room temperature, this effect is reduced to a few percent. Our results show that Sr2CrWO6 is an interesting candidate for room-temperature magnetoelectronic materials. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Clinical studies have shown that estrogen deprivation through menopause is a risk factor in both the initiation and progression of Alzheimer's disease (AD) and that estrogen replacement therapy may be protective. One of the major pathological features in the human AD brain is the senile plaque, a proteinaceous structure composed mainly of heterogeneous peptides collectively known as A-beta (Aβ). In vitro studies have linked estrogen with Aβ modulation, suggesting that one-way that estrogen depletion at menopause may exacerbate the features of AD is through Aβ accumulation. To test this, two studies were performed on transgenic models of amyloidosis. Firstly, transgenic mice without detectable amyloid aggregates were subjected to ovariectomy and estradiol supplementation, and Aβ levels were assessed. Secondly, the effects of estrogen modulation were assessed in mice at an age when plaques would be forming initially. Overall, Aβ levels were higher in estrogen-deprived mice than intact mice, and this effect could be reversed through the administration of estradiol. These data suggest that, in vivo, estrogen depletion leads to the accumulation of Aβ in the CNS, which can be reversed through replacement of estradiol. These results provide evidence that post-menopausal estrogen depletion may be linked to an increased risk of AD through Aβ modulation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 58 (2001), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Analysis of mitochondrial (ND-1/3/4 genes) and nuclear (GH-1 gene, four microsatellite loci) DNA markers of European grayling Thymallus thymallus populations identified strong genetic differentiation between the Rhine/Main, Elbe and Danube drainages in Bavaria, as a result of both present processes and past history. The Danube and the Main-Elbe group diverged about five times earlier than the populations of Main and Elbe. These data suggest that exchange and transfer of grayling stocking material between these drainages should be avoided, to maintain the genetic diversity and integrity of populations.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 92 (1970), S. 2179-2180 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of geodesy 73 (2000), S. 627-637 
    ISSN: 1432-1394
    Keywords: Key words: Earth rotation – Combination – Kalman filter
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract. Independent Earth-orientation measurements taken by the space-geodetic techniques of lunar and satellite laser ranging, very-long-baseline interferometry, and the global positioning system have been combined using a Kalman filter. The resulting combined Earth-orientation series, SPACE97, consists of values and uncertainties for universal time, polar motion, and their rates spanning the period 28 September 1976 to 3 January 1998 at daily intervals. The space-geodetic measurements used to generate SPACE97 have then been combined with optical astrometric measurements to form two additional combined Earth-orientation series: (1) COMB97, consisting of values and uncertainties for universal time, polar motion, and their rates spanning the period 20 January 1962 to 1 January 1998 at 5-day intervals, and (2) POLE97, consisting of values and uncertainties for polar motion and its rate spanning the period 20 January 1900 to 21 December 1997 at monthly intervals.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 45 (1967), S. 1142-1147 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Comparative studies on the effect of incubation of EDTA-plasma at 37° C on platelet aggregation are presented. The aggregation of platelets was determined simultaneously by a microscopic and a fotometric method. After incubation of platelet rich plasma at 37° C for at least 10 min no aggregates can be detected by the fotometric method. Microscopical investigation reveals loose aggregates with altered formation kinetics. Because of chronological formation of the aggregates platelets from different blood-donors can be classified in different groups. The behaviour of platelets towards temperature is defined as “incubation resistance”. Parallel with the investigation of incubation of EDTA-plasma tests were done with recalcified EDTA-plasma. In this case aggregates can be found with both methods. The kinetics of aggregation are those of platelets which have not been incubated prior to addition of Calcium.
    Notes: Zusammenfassung Es werden vergleichende Untersuchungen über den Einfluß der Inkubation von EDTA-Plasma bei 37° C auf die Plättchenaggregation mit Hilfe der Rühr- und Kammermethode beschrieben. Nach Inkubation bei 37° C zeigte die Rührmethode keine Aggregation mehr an. In der Kammer hingegen fanden sich lockere Aggregate, deren Bildung eine gegenüber den Kontrollen veränderte Kinetik aufwies. Auf Grund des zeitlichen Aggregationsverhaltens bei der Inkubation lassen sich die Plättchen verschiedener Versuchspersonen in Gruppen einteilen. Das Verhalten der Plättchen gegenüber Temperatureinflüssen wird als „Inkubationsresistenz“ bezeichnet. Parallel zu den Inkubationsversuchen mit EDTA-Plasma wurden Inkubationsversuche mit recalcifiziertem EDTA-Plasma durchgeführt. Dabei lassen sich sowohl mit Hilfe der Rühr- als auch Kammermethode Aggregate nachweisen. Die Aggregationskinetik entspricht der nicht inkubierter Plättchen.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 45 (1967), S. 931-939 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A method for the determination of the aggregation of blood platelets is reported, using a phase contrast microscope. The temporal course of the aggregation is followed in a counting chamber. The decrease of the count of free platelets as a measure for the count of aggregates formed proves to be the most sensitive criterion of platelet aggregation. Additionally the count of aggregates per mm3 is determined and the aggregates differentiated for loose, intermediary and compact aggregates. Further a modified photometric method for the determination of the aggregation of platelets is given, using a commercial photometer with an attachment which may easily be built. The two methods are compared for their applicability on the determination of platelet aggregation.
    Notes: Zusammenfassung Es wird über eine Methode zur Erfassung der Plättchenaggregation berichtet, bei der die Aggregation in einer Zählkammer mit dem Phasenkontrastmikroskop beurteilt und in ihrem zeitlichen Verlauf verfolgt wird. Die Abnahme der Zahl der freien Plättchen als Maß für die Zahl der gebildeten Aggregate erweist sich dabei als das empfindlichste Kriterium für die Beurteilung der Plättchenaggregation. Weiter werden die Zahl der Aggregate pro mm3 bestimmt sowie eine Differenzierung in lockere, Übergangs-und kompakte Aggregate vorgenommen. Es wird gleichzeitig über eine Modifikation der photometrischen Methode zur Messung der Aggregation berichtet, die es ermöglicht, ein serienmäßiges Photometer mit Hilfe eines leicht herzustellenden Zusatzes zur Messung zu verwenden. Beide Methoden werden hinsichtlich ihrer Aussagefähigkeit miteinander verglichen.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 49 (1971), S. 1301-1304 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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