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  • 27.60.+j  (3)
  • Renal failure  (2)
  • subarachnoid haemorrhage (SAH)  (2)
  • 1
    ISSN: 0942-0940
    Schlagwort(e): Macrophage ; subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; scanning electron microscope (SEM)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Sixty dogs with experimental subarachnoid haemorrhage (SAH), repeated SAH, and subarachnoid fibrosis (examined three weeks and three months after SAH, and treated with urokinase or dexamethasone) were examined by scanning electron microscope (SEM). The authors observed the resting and activated macrophages, the erythrophagocytosis, and giant cells in the subarachnoid space after SAH. They consider that the macrophages play an important role in the formation of subarachnoid fibrosis, similar to the role of macrophages in fibrosis in other sites.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 0942-0940
    Schlagwort(e): Subarachnoid fibrosis ; subarachnoid haemorrhage (SAH) ; tranexamic acid ; antifibrinolytic therapy ; scanning electron microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effect of antifibrinolytic therapy on posthaemorrhagic subarachnoid fibrosis was observed experimentally in dogs with the scanning electron microscope (SEM). The subchronic subjects, given intravenous injections of tranexamic acid (1 mg/day) for 12 days and sacrificed 3 weeks after cisternal blood injection, showed residual clot with thick fibrosis, especially around the haemorrhage. The chronic subjects, to which the same procedure was applied and which were sacrificed three months after cisternal blood injection, showed significant increases in the subarachnoid fibrosis, most remarkably in the parasagittal region. Tranexamic acid is widely used for preventing the recurrence of subarachnoid haemorrhage. However, it was revealed in this study that antifibrinolytic therapy might increase chronic posthaemorrhagic subarachnoid fibrosis, which is considered to be responsible for communicating hydrocephalus by disturbing epicortical CSF flow4.
    Materialart: Digitale Medien
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  • 3
    ISSN: 1432-1238
    Schlagwort(e): Amikacin ; Pharmacokinetics ; Slow hemodialysis ; Renal failure ; Critically ill patients
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Objective The pharmacokinetics of amikacin were studied in patients undergoing slow hemodialysis (HD). Design Slow HD was performed at the dialysate flow rate of 30 ml/min. After a single intravenous dose of amikacin 5 mg/kg, pharmacokinetic variables were calculated by fitting indivdual concentration-time curves to a two-compartment open model. Patients 6 critically ill patients with renal failure were entered into the study. Results The volume of distribution was 0.35±0.03 l/kg. Total body clearance was 35.1±2.3 ml/min with an elimination half-life of 10.5 h. During a 10.5 h session of slow HD, the serum amikacin concentration decreased from the peak level of 21.3±1.2 mg/l to 7.2±0.9 mg/l. Conclusion Slow HD eliminate amikacin more efficiently than other types of slowly performed renal replacement therapy and had profound effects on the pharmacokinetics. Amikacin elimination by this approach should be taken into consideration for designing a dosage schedule during the treatment.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 347 (1993), S. 41-47 
    ISSN: 1434-601X
    Schlagwort(e): 23.20.-g ; 27.60.+j ; 21.60.Cs
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract High-spin states in107Sn were studied using the reaction54Fe(56Fe, 2pn)107Sn. An odd-parity band was identified as based on thevh 11/2 orbit by measuring theγ-ray linear polarization. Also were confirmed the excited states based on thevd 5/2 andvg 7/2 orbits. The halflives of the 17/2+ and 11/2− states were measured to be 0.25(4) ns and 28(11) ps, respectively. The experimental level structure and its interpretation were in good agreement with a shell model calculation.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 349 (1994), S. 133-142 
    ISSN: 1434-601X
    Schlagwort(e): 23.20.−g ; 27.60.+j ; 21.60.Cs
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract The nuclear precession of106Sn in the 6+ state was measured relative to that of108Sn by the IPAD method: θ(6+;106Sn)/θ(6+;108Sn)=1.06(33). Available data on the 6+ state in108Sn giveg (6+;106Sn)=− 0.14(9), which is consistent with the seniority ν=2 configuration: ({ie133-01}). B(E2; 10+→ 8+) was measured to be 6.4(10) W.u. for106Sn and 0.62(5) W.u. for108Sn. This difference could not be explained by the ν≦4 configurations. The {ie133-02}→13− transition turned out to be an M1/ E2 mixed transition and so the yrast I=14 state was identified with a state of the νh11/2 band.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 343 (1992), S. 261-266 
    ISSN: 1434-601X
    Schlagwort(e): 23.20.−g ; 27.60.+j ; 21.60.−n
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract High spin states in the isotopes105,103In have been studied by in-beamγ-ray techniques. The reaction51V(58Ni, 2p 2n) populated those states in105In. A measurement of the linear polarizations ofγ-rays has revealed a negative-parity band in105In. The reaction48Ti(58Ni,p 2n) produced the isotope103In, which has showed an yrast spectrum similar to that observed in105In. The lifetimes of the 19/2+ and 17/2+ states in107,105In have been measured by the recoil distance method;T 1/2(19/2+)=27±4 ps andT 1/2(17/2+)=1.1 −0.3 +0.6 ns for107In,T 1/2(19/2+)=4±2 ps andT 1/2(17/2+)=0.33±0.10 ns for105In.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1432-1238
    Schlagwort(e): Key words Amino acid ; Nitrogen balance ; Slow hemodialysis ; Critically ill ; Renal failure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Objective: The effects of slow diurnal hemodialysis (slow HD) on amino acid losses and nitrogen balance were studied. Design: Slow HD was conducted for 10 h during the day at the dialysate flow rate of 30 ml/min. The patients received total parenteral nutrition including 40 g of amino acids (6.08 g of nitrogen). The amino acid concentrations in plasma and dialysate were determined and the daily nitrogen balance was calculated from the urea nitrogen appearance. Patients: Six critically ill patients with renal failure were entered into the study. Results: Slow HD eliminated 48.5±4.4 mmol (6.2±0.6 g) of amino acids, representing 16% of the daily amino acid load. The estimated nitrogen balance was –2.3±1.3 g/day. Amino acid nitrogen lost in the dialysate was 1.0±0.1 g, contributing 43% of the daily negative nitrogen balance. Conclusion: The amount of amino acid losses during slow HD should be taken into consideration when designing nutritional schedules for maintaining positive nitrogen balance in critically ill patients.
    Materialart: Digitale Medien
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