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  • 1990-1994  (588)
  • 1905-1909  (161)
  • Inorganic Chemistry  (555)
  • Magnetic resonance imaging  (194)
  • 1
    ISSN: 1432-1920
    Schlagwort(e): Acute traumatic central cord syndrome ; Magnetic resonance imaging ; Pathology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The acute traumatic central cord syndrome (ATCCS) is commonly stated to result from an injury which affects primarily the center of the spinal cord and is frequently hemorrhagic. To test the validity of this widely disseminated hypothesis, the magnetic resonance images [MRI] of 11 consecutive cases of ATCCS caused by closed injury to the spine were analyzed and correlated with the gross pathological and histological features of 3 cervical spinal cords obtained at post mortem from patients with ATCCS, including 2 of patients studied by MRI. The MRI studies were performed acutely (18 h to 2 days after injury) in 7 patients and subacutely (3–10 days after injury) in 4. Ten of the 11 patients had pre-existing spondylosis and/or canal stenosis. The 11th suffered a cervical fracture. All patients exhibited hyperintense signal within the parenchyma of the cervical spinal cord on gradient echo MRI. None showed MRI features characteristic of hemorrhage on T1-weighted spin echo or T2*-weighed gradient echo studies. Gross and histological examination of the necropsy specimens showed no evidence of blood or blood products within the cord parenchyma: the primary finding was diffuse disruption of axons, especially within the lateral columns of the cervical cord in the region occupied by the corticospinal tracts. The central gray matter was intact. In patients with ATCCS, the predominant loss of motor function in thedistal muscles of the upper limbs may reflect the importance of the corticospinal tract for hand and finger function in the primate. In this study, the MRI and pathological observations indicate that ATCCS is predominantly a white matter injury and that intramedullary hemorrhage is not a necessary feature of the syndrome; indeed, it is probably an uncommon event in ATCCS. We suggest that the most common mechanism of injury in ATCCS may be direct compression of the cervical spinal cord by buckling of the ligamenta flava into an already narrowed cervical spinal canal; this would explain the predominance of axonal injury in the white matter of the lateral columns.
    Materialart: Digitale Medien
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  • 2
    ISSN: 1432-1084
    Schlagwort(e): White matter lesions ; Cerebrovascular disease ; Magnetic resonance imaging ; Brain infarction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To establish data about prevalence, number and topography of “unspecific” white matter lesions as seen on MRI, the T2-weighted MRI scans of 83 patients with hyperintense focal white matter changes were reviewed. Patients with known inflammatory central nervous system disease were excluded. There was an approximately linear increase in prevalence and number of lesions with age. Prevalence ranged from 18% in the third decade to over 90% in those over 70 years. We found a close correlation with concomitant periventricular hyperintensity. However, rating of Virchow-Robin spaces did not correlate with the number of white matter lesions. Both hemispheres were involved nearly equally with a minimal non-significant right side preponderance. Lesions showed a strong predilection for the frontal and parietal paraventricular “watershed” areas.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Neuroradiology 33 (1991), S. 357-359 
    ISSN: 1432-1920
    Schlagwort(e): Ganglioglioma ; Neurofibromatosis ; Computed tomography ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We report the occurrence of a left frontal lobe ganglioglioma in a patient with neurofibromatosis type I (von Recklinghausen's disease) and conclude that the occurrence of a cerebral ganglioglioma in a patient with neurofibromatosis must probably be considered coincidental.
    Materialart: Digitale Medien
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  • 4
    ISSN: 1432-1920
    Schlagwort(e): Cerebrotendinous xanthomatosis ; Computed tomography ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We report the findings on cranial computed tomography (CT) and magnetic resonance imaging (MRI) and their correlation with the clinical manifestations, disease severity and biochemical abnormalities in eight patients with cerebrotendinous xanthomatosis. CT revealed cerebral atrophy in seven cases, cerebellar atrophy in four and focal low density lesions in the cerebral white matter in two. T2-weighted MRI showed high signal lesions in the cerebral white matter, focal in four cases and diffuse in one, and in the globus pallidus in three patients, two of whom also had lesions in the cerebellar white matter. While severely affected patients showed variable CT and MRI abnormalities, our cases did not show the dramatic findings expected from the neurological manifestations. Diffuse lesions in the cerebral and cerebellar white matter have been emphasized in previous reports, but in our study the focal lesions in the cerebral white matter were also present; the globus pallidus was frequently involved.
    Materialart: Digitale Medien
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  • 5
    ISSN: 1432-1920
    Schlagwort(e): Nerves, trigeminal ; Parapharyngeal space ; Masticator space ; Magnetic resonance imaging ; Cavernous sinus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary 10 patients with symptoms of mandibular neuralgia formed the basis of this study. They were studied by both enhanced CT and MRI. MRI, better than CT, easily permits distinction between intrinsic and extrinsic lesions and detects involvement of the cavernous sinus and meninges. Morever, because of its multiplanar imaging capability, and ability to portray exquisite anatomic details and characteristic tissue signal intensity, MRI is helpful in the evaluation of tumor involvement for biopsy and preoperative planning for these deep tumours.
    Materialart: Digitale Medien
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  • 6
    ISSN: 1432-1971
    Schlagwort(e): Magnetic resonance imaging ; Pulmonary arteries
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Pulmonary artery anatomy was studied in 36 patients (age range 12 days to 12.83 years, mean 2.9 years) with right ventricular outflow tract obstruction over a 3-year period using a 1.5 Tesla Magnetic Resonance system. Gated spin-echo sequences were obtained in each patient. Image planes used were straight and oblique transverse, oblique coronal, and oblique sagittal. The studies were analyzed retrospectively and comparative angiographic, surgical, and postmortem data was available in all cases. As previously noted with other imaging modalities, multiple views and oblique cuts were found to increase significantly the quality and accuracy of the information acquired. In 12 of the 15 patients who had axial and coronal imaging of both branch pulmonary arteries, the pulmonary arteries were unequivocally demonstrated to at least the first hilar branch. However, early in our experience we missed a number of branch stenoses that developed following surgical anastomoses. These mistakes were caused by inadequate or inappropriate slice acquisition. Magnetic resonance is an important technique for imaging pulmonary arteries. Careful use of the appropriate imaging planes is essential for accurate demonstration of the anatomy.
    Materialart: Digitale Medien
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  • 7
    ISSN: 1433-0350
    Schlagwort(e): Neurofibromatosis ; Magnetic resonance imaging ; Optic glioma ; Visual function ; Visual evoked potentials
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Twenty-five asymptomatic patients with neurofibromatosis type 1 (NF 1), aged 6–21 years, underwent the following examinations: intracranial magnetic resonance testing (MRI), visual acuity testing, ophthalmoscopy, and visual field and pattern reversal visual evoked potentials (VEPs). MRI showed enlargement of one or both optic nerves in six children, with bilateral involvement in three. VEPs were normal in all these patients; two of them had abnormalities on other visual examinations, although there were no subjective visual disturbances. These results show that VEPs cannot be considered as a screening test for optic pathway lesions in children with NF 1, as previously stated, and that other types of visual function examination may be more sensitive. These data may contribute to the establishment of more precise guidelines for the evaluation and treatment of children with NF 1.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Journal of neurology 237 (1990), S. 471-474 
    ISSN: 1432-1459
    Schlagwort(e): Amyotrophic lateral sclerosis ; Progressive muscular atrophy ; Bulbar palsy ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Magnetic resonance imaging (MRI) of the brain was evaluated in 20 patients with motor neuron disease (MND) and in a control group of 11 healthy people. Bilateral increased signal areas of various sizes in the centrum semiovale, corona radiata, internal capsule, pedunculi of midbrain, pons, medulla and even in the frontal lobe, topographically related with the corticospinal tract, were found in 8 out of 20 patients. Three out of 4 patients with progressive bulbar paralisis and 5 out of 11 cases of amyotrophic lateral sclerosis had abnormal MRI. Such MRI abnormalities have neither been found in patients with progressive muscular atrophy nor in controls, suggesting that they may be the hallmark of pyramidal tract degeneration in motor neuron disease.
    Materialart: Digitale Medien
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  • 9
    ISSN: 1619-7089
    Schlagwort(e): Magnetic resonance imaging ; Immunoscintigraphy ; Ovarian carcinoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Eighteen patients with suspected primary or recurrent ovarian carcinoma have been investigated in each case by the assay of serum levels of the antigen CA125, immunoscintigraphy using131I-OC125 antibody and magnetic resonance imaging using a 0.15 Tesla-system. The final diagnosis was confirmed by laparotomy or laparoscopy. Serum levels of CA125 ranged between 5 and 780 units/ml (normal range 〈 35). Antibody images and MRI were truly positive in 11 patients, 2 of whom were subsequently found to have bowel tumours. MRI showed greater detail of smaller lesions whilst immunoscintigraphy was more suited to the detection of distant metastases. In 7 patients the antibody images were positive whilst the serum marker levels were normal. This pilot study provides a preliminary comparison of the more recent techniques currently being evaluated for the detection of ovarian carcinoma.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 589 (1990), S. 187-198 
    ISSN: 0044-2313
    Schlagwort(e): Chemistry ; Inorganic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Beschreibung / Inhaltsverzeichnis: 1,3,4-Oxadiphospholanes and 1,3,4-Thiadiphospholanes from Diphosphorus-substituted 2-Oxa- and 2-Thia-propanesThe synthesis of phosphonates and phosphinates of the type (RO)2(O)PCH2ZCH2P(O)(OR)2, R1(RO)(O)PCH2ZCH2P(O)(OR)2 and R1(RO)(O)PCH2ZCH2P(O)(OR)R1 (with Z = O, S; R = Et, Pri; R1 = Me, Ph) is reported. Acyclic diphosphanes, R1(H)PCH2ZCH2P(H)R2 (with Z = O, S; R1 = R2 = H, Me, Ph; R1 = H, R2 = Me), and 1,3,4-Oxadiphospholanes as well as 1,3,4-Thiadiphospholanes are obtained from the esters by reduction.
    Notizen: Die Darstellung von Phosphonaten und Phosphinaten der Zusammensetzung (RO)2(O)PCH2ZCH2P(O)(OR)2, R1(RO)(O)PCH2ZCH2P(O)(OR)2, und R1(RO)(O)PCH2ZCH2P(O)(OR)R1 (mit Z = O, S; R = Et, Pri; R1 = Me, Ph) wird beschrieben. Durch Reduktion der Ester sind die acyclischen Diphosphane, R1(H)PCH2ZCH2P(H)R2 (mit Z = O, S; R1 = R2 = H, Me, Ph; R1 = H, R2 = Me) und 1,3,4-Oxadiphospholane bzw. 1,3,4-Thiadiphospholane zugänglich.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
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