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  • 11
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 320 (1985), S. 507-519 
    ISSN: 1434-601X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract Electron scattering and charged pion photoproduction at 200 MeV on12C and13C have been studied by the nuclear shell model to investigateM1 andE2 nuclear form factors of the isovector type. Starting with the Op-shell model of Hauge-Maripuu, the effects of core polarization by theM 3Y force and the one-pion-exchange current are taken into account. The effect of core polarization is found to be essential in both electron scattering and pion photoproduction, while the meson-exchange current, which also improves the calculated results, gives contributions of about 10%–15%.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 12
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 10 (1988), S. 121-135 
    ISSN: 1279-8517
    Schlagwort(e): Pancreas ; Lymphatic system ; Cancer ; Macroscopic anatomy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé Une étude détaillée du drainage lymphatique du pancréas a été effectuée afin de poser les bases théoriques d'un curage lymphatique idéal dans la chirurgie d'exérèse du cancer. Une dissection minutieuse des lymphatiques a permis d'obtenir le résultat suivant. Trois voies de drainage principales ont été identifiées: la voie supérieure appartient à la chaîne hépatique commune, les voies moyenne et inférieure rejoignent le groupe ganglionnaire mésentérique supérieur. Tous ces drainages se terminent dans un nœud lymphatique situé à droite de l'origine du tronc cœliaque et de l'artère mésentérique supérieure. Les lymphatiques provenant du col du pancréas convergent également vers le même nœud. Derrière celui-ci existe un autre lymphonœud où se terminent les lymphatiques provenant de la face postérieure de la tête. Ces 2 nœuds adhèrent intimement l'un à l'autre, séparés seulement par le plexus nerveux de la tête du pancréas. Dans ce travail, nous avons utilisé pour ces nœuds les termes de lymphonœud cœliaco-mésentérique droit superficiel et profond. Deux voies de drainage distinctes ont été identifiées au niveau de la moitié gauche du pancréas. L'une longe les vaisseaux spléniques et l'autre accompagne l'artère pancréatique inférieure. Par ces 2 voies différentes les lymphatiques de la moitié gauche du pancréas se terminent dans un nœud situé à gauche de l'origine du tronc cœliaque et de l'artère mésentérique supérieure. Nous l'avons appelé le lymphonœud cœliaco-mésentérique gauche. A partir de ces relais lymphatiques situés de part et d'autre de l'origine des deux artères, des vaisseaux efférents se dirigent vers les nœuds juxta-aortiques: du côté droit, les lymphatiques efférents rejoignent les nœuds inter-aortico-veineux situés au-dessus et en dessous de l'abouchement de la veine rénale gauche dans la veine cave inférieure; du côté gauche ils rejoignent les nœuds latéro-aortiques gauches situés au-dessus et en dessous de la veine rénale gauche; à partir de ces relais les voies efférentes rejoignent l'espace rétro-aortique où elles forment un courant lymphatique ascendant. Notre travail n'a pas permis de découvrir des vaisseaux lymphatiques communiquant avec le système rétro-aortique au-dessus du niveau des artères rénales.
    Notizen: Summary A detailed study of the lymphatics around the pancreas was carried out in order to provide a theoretic basis for ideal lymph-node resection in radical cancer operations. The following results were obtained as a result of minute macroscopic dissection of the lymphatics. Three major pathways are identified on the anterior surface of the head of the pancreas. The upper pathway belongs to the common hepatic group. The middle and lower routes are associated with the superior mesenteric nodal group. All these pathways terminate in the node situated to the right of the origins of the celiac trunk and the superior mesenteric artery. The lymphatics arising from the neck of the pancreas also converge at the same node. Behind this node, there is a terminal node for the lymphatics which arise from the posterior surface of the head. Both nodes are firmly adherent, with only the nerve plexus of the head of the pancreas intervening. In this study, we have named these lymph-nodes Lnn celiacomesenterici dextri superficialis et profundi. Two distinct pathways are identified in the left half of the pancreas. One follows the splenic blood vessels and the other accompanies the inferior pancreatic artery. By way of these routes, lymphatics from the left half of the pancreas terminate in the node situated to the left of the origins of the celiac trunk and superior mesenteric artery. We have applied the term Ln celiacomesentericus sinister to this node. From these lymphatic terminalis on both sides of the origins of the two arteries, efferent vessels are sent to the abdominoaortic nodes: on the right side, efferents reach the inter-aorticovenous nodes lying in the upper and lower angles formed by the inferior vena cava and the left renal vein; and on the left side, they arrive at the left latero-aortic nodes lying above and below the left renal vein. The efferents of these nodes then extend to the retro-aortic space, where they compose an ascending lymphatic system. Our study revealed no lymphatic vessels communicating with the retro-aortic system at levels above the renal arteries.
    Materialart: Digitale Medien
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  • 13
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 10 (1988), S. 11-16 
    ISSN: 1279-8517
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Conclusion Nous avons essayé de faire une analyse systématique du système lymphatique du pancréas en nous basant sur le résultat de la dissection extrêmement minutieuse de 4 sujets adultes. Nous avons pu confirmer le résultat de la plupart des travaux précédents et préciser quelques points auparavant mal définis. Il est très difficile de standardiser une technique de curage lymphatique car de très nombreux facteurs entrent en jeu au moment de l'intervention. Choisir la technique chirurgicale idéale implique une excellente connaissance de la topographie des vaisseaux et des nœuds lymphatiques régionaux. Bien que notre travail soit loin d'être exhaustif, nous espérons que les propositions avancées pourront servir de base au traitement chirurgical radical des cancers du pancréas et des organes de voisinage.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 14
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 66 (1988), S. 724-728 
    ISSN: 1432-1440
    Schlagwort(e): NaCl intake ; Glucose tolerance ; Na+ dependent glucose absorption ; Intracellular Na+ concentration ; Plasma Na+, K+-ATPase inhibitor
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of low and high NaCl diets on plasma glucose and insulin responses to glucose ingestion were investigated in 15 patients with essential hypertension. Oral glucose (75 g) tolerance tests were carried out while patients were taking diets with low (2 g/day) and high (20 g/day) NaCl content. Fasting plasma glucose and insulin levels were both significantly lower during ingestion of the high NaCl diet (p〈0.05). After glucose ingestion, the incremental areas under the two hour plasma glucose and insulin curves were significantly smaller during ingestion of the high NaCl diet (glucosep〈0.005 and insulinp〈0.025). These findings that low NaCl diets increase the glycemic response to glucose loads suggest that use of NaCl restriction for the treatment of essential hypertension may not always be desirable.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 15
    ISSN: 1432-0711
    Schlagwort(e): Tumor marker ; Immunohistochemical investigation ; Peroxidase anti-peroxidase method ; Avidin biotin immunoperoxidase technique ; Tumor specificity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We studied immunohistochemical stains for TPA and CA125 in patients with benign and malignant gynecologic diseases. The results were as follows: (1) CA125 was not found in ovarian mucinous cystadenocarcinoma but was demonstrated immunohistochemically in 82% of ovarian serous cystadenocarcinomas and 83% of Krukenberg's tumors. (2) TPA was demonstrated in 65% of ovarian serous and 75% of ovarian mucinous cystadenocarcinomas, and in 58% of endometrial carcinomas. (3) TPA was found in all trophoblastic tumors examined, while CA125 was found in none. Eighty-three percent of patients with trophoblastic diseases had raised serum TPA levels. (4) When serum CA125 levels were raised, CA125 was demonstrated immunohistochemically in 71% of patients with ovarian serous cystadenocarcinomas, 67% of patients with Krukenberg's tumors and 100% of patients with tubal carcinomas. (5) Despite elevated serum levels, CA125 and TPA were not identified by immunohistochemistry in 64% cases of benign ovarian disease and in 80% of patients with uterine myomata. (6) It would seem that CA125 was more easily released from tumor cells than TPA.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 16
    ISSN: 1432-0711
    Schlagwort(e): Tumor marker ; Combination assay ; Early diagnosis ; Screening
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We studied the pretreatment serum levels of 6 tumor markers in gynecological patients with and without malignant disease. The tumor markers were carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), ferritin, Schwangerschaftsprotein 1 (SP1), Schwangerschaftsprotein 3 (SP3) and cancer antigen 125 (CA125). The results were as follows: (1) Serum CA125 and TPA levels were raised in 81% and 57% of patients with ovarian serous cystadenocarcinoma: CEA and SP3, in 52% and 43% respectively of patients with ovarian mucinous cystadenocarcinoma; CA125, TPA and SP3, in 76%, 48% and 48% respectively of patients with other ovarian malignancies; and TPA and SP3, in 56% and 40% respectively of patients with endometrial carcinoma. (2) Serum levels of TPA, ferritin and CA125 were more often raised with advancing stages of malignant disease. (3) Serum TPA levels were elevated in 55% of patients with stage I endometrial carcinoma, and serum SP3 levels were elevated in 35% of patients with a stage I malignant ovarian neoplasm and in 45% of patients with endometrial carcinoma. (4) One of the 6 tumor markers showed a raised level in 84% of patients with gynecologic malignancy as against 56% in those with benign gynecologic diseases.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 17
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 77 (1988), S. 213-218 
    ISSN: 1432-0533
    Schlagwort(e): Juvenile Parkinson's disease ; Classical Parkinson's disease ; Clinico-pathological comparison ; Lewy body distribution ; Dementia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A clinico-pathological case report on a case of juvenile Parkinson's disease (JPD) with widespread Lewy bodies (LBs) in the brain is presented with comparative morphological studies on two demented cases of “classical” Parkinson's disease (CPD) with disease onset at an older age. The clinical and histological pictures of this JPD case were typical of Parkinson's disease, excepting numerous Lewy bodies in the cerebrum. There were no neurofibrillary change nor senile plaques throughout the CNS. The distribution and histochemical and ultrastructural characters of the histological lesions (i.e., LBs) in the JPD and the two CPD cases were investigated and compared. The comparison showed no qualitative but only quantitative differences between the two types of Parkinson's disease. The present study also revealed that in CPD cases significant numbers of LBs could be present in the cerebral cortex, amygdaloid and claustrum. These lesions can be in part responsible for dementia in CPD.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 18
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 77 (1989), S. 659-663 
    ISSN: 1432-0533
    Schlagwort(e): Acute pandysautonomia ; Autonomic neuropathy ; Acute polyradiculoneuritis ; Guillain-Barré syndrome
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A 46-year-old woman presented acute sensori-motor neuropathy of the Guillain-Barré type, followed by a protracted course of profound autonomic and sensory dysfunction. Tests of autonomic functions showed denervation hypersensitivity. Neuropathologically, the trigeminal sensory nuclei, solitary nucleus, the dorsal columns of the spinal cord and dorsal spinal roots showed severe degeneration. Degeneration was found both in the preganglionic (intermediolateral cell columns of the spinal cord) and postganglionic (sympathetic ganglion and celiac ganglion) neurons of the sympathetic nervous system, and the preganglionic (dorsal motor nucleus of the vagus) and postganglionic (Auerbach's plexus) neurons of the parasympathetic nervous system.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 19
    ISSN: 1432-0533
    Schlagwort(e): Menkes kinky hair syndrome ; Macular mottled mouse ; Mitochondrion ; Cytochromec oxidase ; Gold-labeling immuno-electron microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The macular mottled mouse is a murine model of the kinky hair syndrome, characterized by a deficiency in copper transport. Cytochromec oxidase (CCO), a respiratory enzyme, is located in the inner mitochondrial membrane and consists of seven subunits, along with copper and iron. Biochemical and histochemical findings indicated that CCO activity was decreased in the cerebellum of the macular mottled mice but not in that of the controls. Immunocytochemical analysis, using anti-CCO and anti-complex III rabbit sera, revealed that CCO in the macular mottled mice was stained more weakly than that in the controls. Immuno-electron microscopic examination of CCO and complex III, using a method of gold labeling, was also performed. In the control mice, a high concentration of gold particles present over CCO and complex III could be seen in the inner mitochondrial membrane. The number of CCO-labeled gold particles was remarkably less, however, in the macular mottled mice, while no significant difference was found in the labeling of complex III between the two groups. It may concluded that the very low CCO enzyme content in the macular mottled mouse results not only from a copper transport disorder but also from a CCO protein synthesis disorder which impairs the localization of CCO protein in the cerebellum.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 20
    Digitale Medien
    Digitale Medien
    Springer
    Applied physics 45 (1988), S. 355-360 
    ISSN: 1432-0630
    Schlagwort(e): 81.10 ; 68.55 ; 42.60
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau , Physik
    Notizen: Abstract Diamond-like carbon thin films were prepared by pulsed-laser evaporation. In this method a carbon target was irradiated by a XeCl laser with a power density of 3×108 W/cm2 and carbon atoms, together with a small number of ions, were produced. Deposition rates and film properties changed sensitively with substrate temperature. The films deposited at 50°C were diamond-like, having reasonable hardness, high refractive index (2.1–2.2 at 633 nm), optical transparency in the infrared, electrical resistivity of 108 Ω cm and chemical inertness (no dissolution in a HF∶HNO3 solution). The band gap measured from optical absorption was 1.4 eV. Raman spectrum and infrared absorption, whose features varied with the substrate temperature, were also measured. The films were amorphous and no crystallinity was observed, as confirmed by x-ray diffraction, transmission electron diffraction and Raman spectroscopy. Hydrogen atoms were incorporated in the films with a typical H/C ratio of 0.3. The application of a negative bias to the substrate modified the deposition due to the presence of ions.
    Materialart: Digitale Medien
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