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  • 11
    Electronic Resource
    Electronic Resource
    Comparison of helical CT and MR imaging in detecting and staging small pancreatic adenocarcinoma (1997)
    Springer
    Abdominal imaging 22 (1997), S. 429 -433 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Pancreas, CT—Pancreas, MR—Pancreas, neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To compare the value of helical computed tomography (CT) and various pulse sequences of magnetic resonance (MR) imaging in the detection and staging of small pancreatic adenocarcinoma. Methods: Small pancreatic adenocarcinomas (≤2 cm in diameter) in eight patients were evaluated with both helical CT and MR imaging. Five MR imaging pulse sequences that included fat-suppressed T1-weighted images and dynamic study using fast multiplanar spoiled gradient-recalled technique were compared for the tumor detectability. To evaluate the tumor vascularity, angiographic findings were also investigated. Results: Helical CT delineated the tumor in five cases, and MR imaging depicted the tumor in seven cases. MR imaging could detect the tumor of 0.8 cm in diameter clearly. Although helical CT and dynamic MR imaging missed the tumor of 2 cm with relative hypervascularity, fat-suppressed T1-weighted MR imaging demonstrated it precisely. As for the tumor staging, MR imaging was equal or slightly superior to helical CT. Conclusion: MR imaging is the first modality of choice to evaluate small pancreatic adenocarcinoma, and fat-suppressed T1-weighted images and dynamic study must be performed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900226
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  • 12
    Electronic Resource
    Electronic Resource
    Hepatocellular carcinoma with sarcomatous change: characteristic findings of two-phased incremental CT (1996)
    Springer
    Abdominal imaging 21 (1996), S. 37-40 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver〈+〉—〈+〉Liver, neoplasms〈+〉—〈+〉Hepatocellular carcinoma〈+〉—〈+〉Sarcomatous change〈+〉—〈+〉Computed tomography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. Methods: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. Results: All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathologically, delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. Conclusions: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900006
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  • 13
    Electronic Resource
    Electronic Resource
    Helical CT evaluation of arterial invasion in pancreatic tumors: comparison with angiography (1997)
    Springer
    Abdominal imaging 22 (1997), S. 204 -207 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Pancreas—Helical CT—Peripancreatic arteries—Pancreatic tumors.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: Although helical computed tomography (HCT) has been widely employed for the evaluation of pancreatic tumors, its capability in the diagnosis of peripancreatic arterial invasion has not been established. Methods: HCT with a sequential cine-display was carried out in 34 patients with solid pancreatic tumors and 28 control subjects without angiographic abnormality. The HCT scans were compared with angiograms. Results: All major arteries (celiac, superior mesenteric, splenic, gastroduodenal) and superoanterior pancreaticoduodenal arteries were well demonstrated by HCT in control subjects. However, posterior pancreaticoduodenal arcades and other smaller arteries were poorly identified. Although 19 major arterial invasions were equally diagnosed by HCT and angiography in patients with pancreatic tumors, only 4 of 11 minor arterial invasions were correctly diagnosed by HCT. Conclusions: Although HCT has some limitations in the evaluation of minor peripancreatic arteries, it can provide enough information for making a decision about conducting pancreatic surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900173
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  • 14
    Electronic Resource
    Electronic Resource
    MR imaging of hepatocellular carcinomas: effect of Cu and Fe contents on signal intensity (1997)
    Springer
    Abdominal imaging 22 (1997), S. 60 -66 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver, neoplasms—Liver, metal—Magnetic resonance imaging—Hepatocellular carcinoma—Liver, signal intensity. [xm [fs99]
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To elucidate the metallic factors contributing to the signal intensities of hepatocellular carcinoma (HCC) on T1-weighted magnetic resonance (MR) images and to determine whether or not changes in signal intensity contribute to the diagnosis of histological grading of HCC. Methods: In 35 patients immediately after surgery, the quantities of water, lipid, copper (Cu), iron (Fe), and manganese (Mn) were determined in HCCs and the surrounding hepatic parenchyma. The correlations among these findings, the histopathological findings, and the signal intensities of T1-weighted MR images were evaluated. Results: Among the 35 HCCs, 12 (34%) were of high intensity, 14 (40%) were isointense, and 9 (26%) were of low intensity on T1-weighted images versus the surrounding hepatic parenchyma. The paramagnetic ions, which contributed to the signal intensity patterns, were assumed to be Cu in HCCs (30.5 ± 52.9 μg/g ww), and Fe in the livers (106.2 ± 86.8 μg/g ww) and HCCs (87.7 ± 49.1 μg/g ww). In 12 HCCs with high intensity, one was grade I, eight were grade II, and three were grade III according to Edmondson-Steiner's histopathological classification. Conclusions: Signal intensity and signal intensity patterns alone cannot be signs of low-grade malignancy because of the Fe in livers and in HCCs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900141
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  • 15
    Electronic Resource
    Electronic Resource
    Primary malignant lymphoma in the porta hepatis: a case report (1996)
    Springer
    Abdominal imaging 21 (1996), S. 448-450 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver, neoplasm—Liver, lymphoma—Porta hepatis, lymphoma—MRI—CT.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A case of primary lymphoma in the porta hepatis is presented here. Cholangiography, angiography, ultrasonography and computed tomography suggested the presence of a mass in the porta hepatis, but all these failed to demonstrate the tumor clearly. Magnetic resonance imaging was very useful in defining the characteristics of the tumor and in delineating its extent, though it was not specifically diagnostic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900101
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  • 16
    Electronic Resource
    Electronic Resource
    Radiologically identifiable intratumoral portal vein in intrahepatic cholangiomas: a diagnostic pitfall (1996)
    Springer
    Abdominal imaging 21 (1996), S. 445-447 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver neoplasm—Cholangioma—Intratumoral portal vein—MR—CT.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: Although intratumoral patent portal vein (ITPV) is one of the characteristic features of benign hepatic lesions, ITPVs can be demonstrated in malignant tumors. We present the spectrum of MR and CT findings of ITPV identified in intrahepatic cholangiomas with pathological correlations. Methods: The ultrasound, CT and/or MRI findings of pathologically-confirmed intrahepatic cholangiomas were reviewed and correlated with surgical specimen or autopsy findings. Results: Intratumoral patent vessels were radiographically-demonstrated in 5 patients with intrahepatic cholangiomas. All intratumoral vessels were secondary or tertiary order portal vein branches. Some wall thickening was identified on pathological examinations. Conclusion: The radiological demonstration of intratumoral portal vein is not a specific sign of benignity. In the case of a hepatic tumor with a patent portal tract, cholangioma should be considered, as well as benign tumors or lymphoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900100
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  • 17
    Electronic Resource
    Electronic Resource
    Culture experiments on the sea urchin Strongylocentrotus pulcherrimus fed an artificial diet (1975)
    Springer
    Marine biology 29 (1975), S. 105-108 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The omnivorous sea urchin Strongylocentrotus pulcherrimus inhabits the coast of Japan. It also ingests foreign foods, which are not normally present in the natural habitat. In cultures, foreign foods, such as white fish meal, shellfish meal, milk casein, gelatin, soybean meal, yellow corn, alfalfa and yeast were provided in the form of a moist and soft material and their ingestion and digestibility were examined. The foreign foods were prepared by mixing with agar-agar. Digestibility of the diet, and that of nitrogen contained in the diet, was estimated as 54.7 and 64.7% dry weight. Sea urchins cultivated over a period of 5 months on such a foreign diet exhibited 24% increase in wet weight during this period. Occasionally, the ingestion of artificial food suddenly decreased, but was soon resumed upon supplying a hot-water extract of brown algae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00388981
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  • 18
    Electronic Resource
    Electronic Resource
    Polymorphic sparteine metabolism and amyotrophic lateral sclerosis (1989)
    Springer
    Journal of neurology 236 (1989), S. 452-455 
    Details
    ISSN: 1432-1459
    Keywords: Amyotrophic lateral sclerosis ; Cytochrome P450 enzymes ; Sparteine sulphate ; Nitro-oxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The activity of detoxication with the cytochrome P450 family of enzymes was studied in patients with amyotrophic lateral sclerosis (ALS). The metabolic ratio (MR) of sparteine sulphate was measured, and the population of phenotypes for sparteine nitro (N)-oxidation was determined in 30 patients with ALS and 41 controls for the assay of the sparteine N-oxidation by the cytochrome P450 enzymes. A lower MR and higher frequency of efficient metabolizers were observed in the ALS group, suggesting that there is efficient sparteine N-oxidation by cytochrome P450 pathways in ALS. This tendency was more marked in 15 patients with ALS aged under 60 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00328505
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  • 19
    Electronic Resource
    Electronic Resource
    Atypical motor neuron disease with severe ophthalmoloplegia: a report of two cases (1995)
    Springer
    Journal of neurology 242 (1995), S. 541-546 
    Details
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00867427
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  • 20
    Electronic Resource
    Electronic Resource
    Lord-type uncemented total hip arthroplasty — its application to Japanese patients, long-term results and problems (2000)
    Springer
    European journal of orthopaedic surgery & traumatology 10 (2000), S. 189-191 
    Details
    ISSN: 1432-1068
    Keywords: Uncemented ; Total hip arthroplasty ; Long term
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated 270 patients (321 hips) treated by Lord-type cementless total hip arthroplasty (THA) and reported results in 234 hips that could be directly observed among 251 that were 5-year or more after operation. The mean Merle d'Aubigné and Postel hip score improved from 8.9 before operation to 15.7 at the final follow-up. However, our 20-year experience showed revision due to aseptic loosening in 27 patients. In particular, biological fixation could not be achieved in some cases treated using a screw-in ring for acetabular dysplasia or using the Fluted type stem with a smooth surface. This may be the cause of aseptic loosening, and further follow up is necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01682315
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