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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Digestive diseases and sciences 43 (1998), S. 2384-2391 
    ISSN: 1573-2568
    Schlagwort(e): ELECTROGASTROGRAPHY ; FUNCTIONAL DYSPEPSIA ; GASTROINTESTINAL MOTILITY ; GASTRIC EMPTYING
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The aim of this study was to investigateabnormalities in pediatric patients with functionaldyspepsia. Fifteen symptomatic pediatric patientsdiagnosed with functional dyspepsia and 17 aged-matchedhealthy controls were studied. Gastric myoelectricalactivity was recorded using surface electrogastrographyfor 1 hr in the fasting state and 1 hr after a testmeal. It was found that, in comparison with thecontrols, the children with functional dyspepsia had alower percentage of 2- to 4-cpm slow waves in bothfasting state (66.0 ± 4.7% vs 79.7 ± 3.1%,P 〈 0.07) and fed state (72.4 ± 5.4% vs 85.0± 2.9%, P 〈 0.04), and a significantly higherinstability of the dominant frequency in both fastingstate (0.50 ± 0.05 vs 0.31 ± 0.04, P 〈0.01) and fed state (0.39 ± 0.05 vs 0.25 ±0.03, P 〈 0.05). It was also found the postprandial increase inEGG dominant power in the patients was inverselycorrelated with the total symptom score (r = 0.63, P =0.03). It was concluded that abnormal gastricmyoelectrical activity may play a role in the pathogenesis ofpediatric functional dyspepsia.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Digestive diseases and sciences 43 (1998), S. 1678-1684 
    ISSN: 1573-2568
    Schlagwort(e): ELECTROGASTROGRAPHY ; GASTROINTESTINAL MOTILITY ; FUNCTIONAL DYSPEPSIA ; GASTRIC EMPTYING
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The aim of this study was to investigate gastricmyoelectrical activity in patients with functionaldyspepsia. Thirteen healthy subjects and 14 patientswith functional dyspepsia participated in the study. The electrogastrogram (EGG) recording was madein each subject for 30 min in the fasting state and 120min after a standard test meal of 475 calories. Spectralanalysis methods were applied to derive quantitative EGG parameters. There was no difference in theEGG between the patients and controls in the fastingstate. However, abnormalities in the postprandial EGGwere found in the patients. The percentage of 2-4 cpmwaves was significantly lower (74.4 ± 4.0% vs85.7 ± 1.6%, P 〈 0.03) and the postprandialincrease in EGG dominant power was significantly less(–0.52 ± 0.92 dB vs 2.24 ± 0.88 dB,P 〈 0.03) in patients than in controls. It was alsofound that the percentage of postprandial 2-4 cpm wavescould be used to differentiate the patients withfunctional dyspepsia from the healthy controls with a specificity of 100% and a sensitivity of 43%. It was concluded that a subset of patients withfunctional dyspepsia have impaired gastric myoelectricalactivity in the fed state.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Digestive diseases and sciences 43 (1998), S. 1023-1030 
    ISSN: 1573-2568
    Schlagwort(e): ELECTROGASTROGRAPHY ; GASTROINTESTINAL MOTILITY ; GASTRIC EMPTYING ; STOMACH
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The efficiency and efficacy of theelectrogastrogram (EGG) involve a few practical factors,including recording length, sample size, and thecharacteristics of subjects. The aim of this study wasto investigate the effect of these factors on the accuracy ofEGG analysis. Gastric myoelectrical activity wasrecorded using electrogastrography in 24 subjects (ages22-91 years) for 1 hr in the fasting state and 2 hr after a test meal. Computerized spectralanalysis was performed to compute EGG parameters,including dominant frequency, dominant power, and thepercentage of 2-4 cycles per minute (cpm) slow waves. A parameter called misinterpretation was definedto investigate the effect of recording length. Theresults were as follows: (1) Using the recording lengthof 1 hr in each state as a gold standard, themisinterpretation for the recording length of 30 min was 27% forthe dominant frequency and 17% for the dominant power.When the recording length was reduced to 15 min, themisinterpretation increased to 61% for the dominant frequency and 38% for the dominant power. (2)With a sample size of 10 subjects and a recording lengthof 60 min, a statistically significant postprandialincrease was observed in the dominant frequency and power, and a trend in the postprandialincrease of the regularity of the EGG was noted. Whenthe sample size increased to 24 subjects, a significantpostprandial increase was found in all these parameters. (3) None of the EGG parameters exhibited anysignificant difference between the younger and oldersubjects or between men and women. In conclusion, arecording length of 30-60 min seems to be appropriate and produces reliable and predictable results.Age and gender do not affect any of the EGGparameters.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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