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  • 1975-1979
  • 1960-1964  (333)
  • 1915-1919
  • 1890-1899
  • 1963  (333)
  • Cell & Developmental Biology  (333)
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Years
  • 1975-1979
  • 1960-1964  (333)
  • 1915-1919
  • 1890-1899
Year
Keywords
  • 101
    Electronic Resource
    Electronic Resource
    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450401
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  • 102
    Electronic Resource
    Electronic Resource
    Retardation of the newt limb regeneration with semicarbazide, an inhibitor of histamine formationSupported by a grant from the National Science Foundation (G-6146). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 225-233 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: It is widely known that the substance histamine is a noxious agent released from cells when they are injured. At the outset these experiments were intended to show whetherhistamine, persumably released by newt limb amputation, might also promote beginning steps in regeneration. In addition, according to a new view of the physiology of histamine, its formation metabolically by the decarboxylation of histidine is an attribute of the rapid growth of many tissues. These experiments were mainly designed to interfere with histamine production and thereby disrupt the rapid growth of the limb regenerate.Semicarbazide has been used successfully in mammals to inhibit histidine decarboxylase and decrease the rate of histamine formation. In these experiments, semicarbazide was administered to stumps of amputated newt limbs by microinfusion for many hours at a time in efforts to decrease histamine formation and retard growth.When semicarbazide was infused into the limb only in preblastemal stages of regeneration, it seemed to have no effect on the course of regeneration. When it was infused directly into the early mesenchymatous blastema, however, it retarded the expansion and differentiation of the blastema. From present evidence, it appears that histamine production may not be concerned in the initiation of limb regeneration but is probably concerned in the phase of rapid blastemal enlargement, whose primary histological attribute is cellular mitosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460307
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  • 103
    Electronic Resource
    Electronic Resource
    Improved fluids for anatomical embalming and storage (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 241-243 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: An improved embalming fluid has been developed for anatomical use. Potassium pyrophosphate and magnesium chloride are used to decrease the rigidity associated with formalin fixation. Substitution of sodium pentachlorophenate for phenol improves color relationships and eliminates most of the unpleasant cadaver odor. It gives as much, or more, protection against bacteria and fungi. Sorbitol replaces glycerine as a humectant with less browning of tissues, and a wetting agent is incorporated to facilitate distributionand penetration of the fluid.Wet storage of cadavers is recommended, and a vat fluid is described for use with the new embalming formula.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460309
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  • 104
    Electronic Resource
    Electronic Resource
    Plastic mounting of microscopic serial sectionsSupported by grant NB-02896, National Institutes of Neurological Diseases and Blindness, United States Public Health Service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 235-239 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A technique is described for mounting both small and large serial sections on Dupontleader film or pieces of Mylar-D plastic sheeting. The blocks are processed in the usual fashion and embedded in paraffin or celloidin. Small sections are mounted serially on five-foot strips of 35 mm film in a gelatine waterbath and allowed to dry. The film strip is placed on a Nikor developing reel, the paraffin dissolved, the tissue hydrated, and the staining carried out in the usual fashion. The sections are cleared and allowed to dry and then covered with Varathane which hardens in 24 hours. The film strips are stored on 35 mm spools. Large paraffin embedded sections are processed separately in a similar fashion, mounted on Mylar-D sheets, and stored in a loose-leaf notebook. When celloidin is used it must be removed before mounting. The sections can be studied microscopically by passing the film over the stage of a microscope in a sequential fashion. The advantages of the method are discussed.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460308
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  • 105
    Electronic Resource
    Electronic Resource
    Intersexuality with associated mammary gland stimulation in the ratSupported in part by a grant from the American Cancer Society. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 245-249 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Spontaneous intersexuality in an adult rat, thought to be genetically male, has beendescribed. Both male and female primordia developed concurrently and most components ofeach were retained with normal adult characteristics. Gonadal and hypophyseal hormones in this specimen stimulated ductal and lobulo-alveolar proliferation simulating that of the mammary gland during lactation.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460310
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  • 106
    Electronic Resource
    Electronic Resource
    Morphological characteristics of the anterior mesenteric artery of fowlPublished as paper no. 4904 Scientific Journalseries at Minnesota Agricultural Experiment Station. This investigation was supported in part by research grant from National Heart Institute, Public Health Service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 251-255 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The anterior mesenteric artery of two species of fowl, the turkey and chicken, is found to differ structurally from the basic pattern observed in other avian arteries and in mammalian arteries in general. This difference in structure lies in the fact that the avian anterior mesenteric artery contains two well-developed muscular components: an inner circular, and an outer longitudinal, analogous to the arrangement of the muscularis externa of the intestinal wall. However, the evidence presented indicates that the outer longitudinal layer is part of the adventitia. The possible functional significance of this feature is discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460311
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  • 107
    Electronic Resource
    Electronic Resource
    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460401
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  • 108
    Electronic Resource
    Electronic Resource
    An enzymatic-histochemical study of the corpus uteri of the mouse (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 263-279 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The authors have investigated in the component parts of the uterine corpus of the C3H/N mouse the distribution pattern of 15 enzymes, some of them for the first time. In the endometrial epithelium alkaline and acid phosphatase, 5-nucleotidase, adenosinetriphosphatase, β-glucuronidase, NADD, NADPD, and the dehydrogenases studied, were found to show cyclical variations in intensity and localization which parallel the estrogen impregnation of the animal. Cyclical variations in intensity were found in the endometrial stroma for the activity of alkaline phosphatase, adenosinetriphosphatase, and β-glucuronidase. Analogous variations in the myometrium are reported for alkaline phosphatase and β-glucuronidase. A relationship between the functional activity of fibroblasts and the intensity of the activity of alkaline phosphatase is suspected in the subepithelial connective tissue. Macrophages show activity of a variety of enzyme systems. Their high acid phosphatase activity is to be attributed to storage of organic substances deriving from the breakdown of the endometrial epithelium. A similar relationship between enzyme activity and storage function is suspected for β-glucuronidase. The sudden increase in the aminopeptidase activity in the endometrial epithelium and stroma at the end of the estrous cycle may be the expression of the intense catabolic phenomena which characterize this phase.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460313
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  • 109
    Electronic Resource
    Electronic Resource
    Number of rat ova implanting after sub-sterilizing X-irradiation of one or both ovariesAided by grants from National Institutes of Health, United States Public Health Service and the University of Illinois Research Board, The Graduate College. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 257-261 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Irradiation with 800 r of x-ray was applied to the exteriorized left ovary, to both ovaries or to the left ovary after unilateral (right) castration of 60day old rats. Treated females were placed with the male at 60, 70, 80 or 90 days of age. Females were explored at eight or nine days after sperm were found in the morning smears to determine the number of implanations.The number of matings was reduced during the period of normal vaginal cycles. Matings did occur after the unset of continuous vaginal cornification.Animals with an irradiated left and a normal right ovary maintained an average number of implantations through pregnancies one to seven. The normal ovary compensated for the loss of production by the irradiated ovary. Bilateral irradiation caused a decrease in implantations in the second and third pregnancies. In individual cases, however, thenormal complement for a single ovary occurred as late as 201 days after irradiation. The irradiated ovary in the absence of the other ovary compensated by producing more implantations; its period of production was limited to 31 days following irradiation.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460312
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  • 110
    Electronic Resource
    Electronic Resource
    The fine structure of regenerating adrenocortical autotransplants in the ratThis work was supported in part by U.S.P.H.S. grants HE-06214 and D-662. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 319-335 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structural changes accompanying the regeneration of adrenocortical transplants in the rat were studied with the electron microscope. One-half gland autotransplants were made to the dorsal musculature of male Wistar rats, weighing approximately 120 gm. Transplants were recovered after 2, 4, 7, 14, 21 and 60 days of regeneration. During the first week of regeneration there was an increase in the granular endoplasmicreticulum at the expense of the agranular form. The internal structure of the numerous mitochondria was transformed from the normal tubular and vesicular forms of the zonae glomerulosa and fasciculata, respectively, to a lamellar type. The quantities of free ribonucleoprotein particles also were reduced. During this period the viable cortical cells are considered to be more deeply involved in protein synthesis and growth rather than hormone biosynthesis. Following 14 days of regeneration and thereafter, the characteristics of the mal intact adrenal cortex became established. Highly osmiophilic “dark cells,” present in the inner zones of the normal intact adrenal cortex, firstappeared after 14 days of regeneration, and were widely scattered throughout the cortexafter three weeks. After two months of regeneration, the “dark cells” were again concentrated in the inner cortical zones. During this latter period, hormone biosynthesis appears to be the major cell function. Possible structural-functional relationships are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460406
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  • 111
    Electronic Resource
    Electronic Resource
    Normal and abnormal expansion of the lungs of newborn infants obtained at autopsySupported by research grants of the united cerebral palsy research and educational foundation, and the public health service (GM 08754). III. The pattern of aeration as affected by gestational and postnatal age (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 337-351 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Lungs of 482 infants were examined by artificial inflation. The pattern of aeration is recognized best when expansion is incomplete. It varies strikingly with maturity: inpreviable fetuses (approximately 1,000 gm or less) and in mature infants (above 2,000 to 2,500 gm) air is distributed at random. In viable premature infants with a birth weight between these two groups, aeration of the bronchi and respiratory bronchioles without expansion of the alveoli (atelectasis of prematurity) is accomplished with relative ease, whereas opening of the alveoli requires much higher pressure. In infants born too small for their gestational age, the pattern of expansionfollows gestational age rather than birth weight. If the normal surface active lining of the air spaces is inactivated or absent, the stability of expansion is reduced and extensive collapse occurs at each expiration. This favors in the lungs of premature infants the recurrence, and eventually persistence of atelectasis of prematurity. Expansion by liquid media shows that the architecture of these atelectatic lungs is normal. The tendency toward atelectasis of prematurity is a function of prematurity, and is independent of the formation of hyaline membranes.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460407
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  • 112
    Electronic Resource
    Electronic Resource
    A quantitative study of human superior cervical sympathetic ganglia (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 353-356 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The postganglionic neurons in four human superior cervical sympathetic ganglia and the preganglionic axons in the trunks just caudal to these ganglia were counted. The number of postganglionic neurons varied from 760,370 to 1,041,652. The estimates of the number of preganglionic fibers ranged from 5,305 to 12,008. The resulting ratio of preganglionic to postganglionic neurons was as high as 1 to 63 in one ganglion and as low as 1 to 196 in another. The number of postganglionic neurons in human superior cervical sympathetic ganglia is approximately ten times greater than the figure obtained in the cat and 20 times greater than in rabbit ganglia. The number of preganglionic axons does not vary proportionally and is of the same order of magnitude in cat, dog and man.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460408
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  • 113
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    The preferential removal of bone and tooth collagenSupported in part by P.H.S. Grant no. DE-01785-01 from the National Institutes of Health and General Research Grant no. 1-GS-15 U.S. Public Health Service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 357-363 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This investigation was undertaken to remove collagen from bone and tooth sections following fixation, decalcification and sectioning so that the noncollagenous tissues could be better demonstrated. Half heads of white mice were fixed in one of the following:Susa, neutral buffered formalin, ethyl or methyl alcohols. Decalcification was carried out with formic acid-sodium citrate solution, hydrochloricformic acid mixtures, formic acid alone, or the tetrasodium salt of ethylenediamine tetra-acetic acid. Paraffin sections were cut at 8 μ. After deparaffinization and hydrations the sections were immersed in one of two solutions, distilled water alone or 0.1% solutionof collagenase in distilled water. The experimental sections were incubated at 37°Cfor periods ranging from two to four days. Sections were then stained with picro naphthol blue black, hematoxylin and eosin, Van Gieson's stain or Masson's stain. The distilled water sections showed no change. The collagenase treated sections showed that the collagen had been removed from the matrix of bone and dentin leaving behind theosteocytes and odontoblast processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460409
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  • 114
    Electronic Resource
    Electronic Resource
    American Association of Anatomists (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 381-436 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460412
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  • 115
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    Galen on anatomical procedures, the Later Books, by W. L. H. Duckworth, edited by M. C. Lyons and B. Towers. xix + 279 pages. $7.50. The Cambridge University Press, New York (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 373-376 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460411
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  • 116
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    Fine structure of splenic pulpSupported by grants from the Greater New Orleans Cancer Association, and the National Institutes of Health (H-2549). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 25-41 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Splenic tissue from the dog, monkey, guinea pig, and rat were fixed in OsO4, embedded in maraglas, and examined by electron microscopy. The red pulp is composed of sinuses, the walls of which are formed by littoral cells (macrophages and fixed reticulum cells) resting on a framework of reticulum. The pulp cords (Billroth cords) are formed by sinuses containing bands of reticulum which compartmentalize the cord. Interlocked littoral cells and entrapped formed elements of the blood are found in the cords. The stroma of the white pulp is composed of two types of fixed reticular cells (fixed reticular cells, type A; and fixed reticular cells, type B), macrophages, and cell types intermediate between macrophages and fixed reticular cells. The reticulum of the white pulp is similar to that of the red pulp. With PTA staining the extracellular connective tissue (reticulum) is found to be composed of a homogeneous substance with fibrillar elements, namely (1) fibrils 50 mμ in diameter with a 640 Å axial periodicity, (2) fibrils of similar diameter without periodicity, and (3) non-periodic, closely packed undulating, parallel fibrils ca. 70 Å in diameter. The reticulum is, in general, enclosed by cytoplasm of littoral cells or sandwiched between cells; rarely, however, the reticulum appears to be in contact with the blood in the sinus. The junction of capillary and sinus is abrupt and the terminal capillary endothelium is surrounded by litoral cells.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470105
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  • 117
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    The fine structural localization of some testicular phosphatasesThis work was supported by grants from the National Institute of Arthritis and Metabolic Diseases (A-3688) from the National Cancer Institute (CRT-5055) and the National Heart Institute H-5906, National Institutes of Health, Department of Health, Education and Welfare. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 43-63 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The distribution of several nonspecific and nucleoside phosphatase activities in rat testis fixed in glutaraldehyde was studied with the electron microscope. Seven apparently discrete distributions of activity were found. Nonspecific phosphatase activity at neutral pH was found in the basement membrane of seminiferous tubules, as well as in pinocytic vesicles in connective tissue cells underlying the tubules. Acid phosphatase activity was associated with the dense bodies of Sertoli cells, and with the Golgi apparatus of all spermatogenic cells. In addition, the Golgi apparatus of spermatogenic cells exhibited activity to both nucleoside di- and tri-phosphates. The Golgi apparatus of the Sertoli cells exhibited both di- and triphosphatase activity, but no glycerophosphatase activity.Triphosphatase activity was also found at the cell surfaces of spermatogenic cells in some stages of development. Spermatogonia and early spermatocytes exhibited activity to both ATP and ITP. Little triphosphatase activity was found at the cell surfaces of secondary spermatocytes or early spermatids, while pronounced activity was seen at the surfaces of late spermatids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470106
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  • 118
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    Fine structure of the rectal (salt-secreting) gland of the spiny dogfish, Squalus acanthias (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 95-127 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The rectal gland of the spiny dogfish, Squalus acanthias has been described by light and electron microscopy. The cell outline shows remarkable complexity in electron micrographs. The basal plasma membrane has numerous complex infoldings and interdigitations separated by groups of mitochondria. The lateral plasma membrane also shows extensive interdigitation. The apical region demonstrates profiles of interleafing cell processes with much membrane interdigitation occurring between them but containing few mitochondria. The apical surface has microvilli which extend into the tubular lumen and are covered with nap-like filaments. Glands of some fish were catheterized and attempts were made to correlate the fine structure of these glands with the known secretory rates. The cellular morphology of the secretory cells of the rectal gland correlates well with that seen in other ion-transporting tissues, although some unique specializations were noted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470108
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  • 119
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    Light and electron microscopy of the islets of langerhans of the saimiri monkey pancreasSupported by U.S.P.H.S. grants H-1663 and H-173. This report was submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 65-93 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The distribution of alpha, beta, and other islet cells in the tail of the pancreas of the Central American monkey (Saimiri sciurea) revealed by the light and electron microscopes, is similar to that occurring in man. Differentiation of acinar, islet and duct cells is based on the presence or absence of specific granules and the special morphology of the cytoplasm and its membrane systems. Conspicuous lipid droplets appear in the islets, largely confined to beta and delta cells. An “intergrade” cell is present, possessing features of both alpha and beta cells, as well as a nongranular variety of delta cells.Nerve processes which display synaptic vesicles and clusters of mitochondria are present within the islets. Islet and acinar cells are sometime separated by connective tissue or a reticulum, as observed in light microscopy, but there may be simple apposition of their respective plasma membranes. The fine structure of this reticulum presents several levels of organization. Duct cells possess lipid masses similar to those in islet cells. These duct cells, unlike islet cells, are agranular and possess microvilli and cytoplasmic blebs, both of which show internal structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470107
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  • 120
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    Observations on the sequence of blastemal condensations in the limbs of the mouse embryoThis work was supported by research grants C-3613 and AM-06428 from the National Institutes of Health, U. S. Public Health Service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 129-137 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In the forelimbs, the sequence of blastemal condensation is: scapula and humerus, ulna, digit IV, digit V, radius, digit III, digit II, digit I. In the hind limb, the sequence is: innominate bone and femur, fibula, digit IV, digit V, tibia, digit III, digit II, digit I. The sequence described may lead to loss of preaxial parts of the limb in cases of severe over-all reduction of limb bud material due to genetic or teratogenic agents. The main reason why ectrodactyly and polydactyly in the mouse are usually preaxial is the localization for some unknown reason of alterations in growth rate in the preaxial margin of the footplate. However, the fact that blastemal condensations begin postaxially will tend to confine these and similar skeletal anomalies of the limb to the preaxial part.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470109
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  • 121
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470201
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  • 122
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    Lipid-depleted white adipose cells: An electron microscope studySupported by grant AM 03379-04, Division of Arthritis and Metabolic Diseases, U.S.P.H.S. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 273-293 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This report presents an electron microscope study of white adipose cells depleted of their lipid inclusion by prolonged low food intake. The tissue was fixed in phosphate-buffered 1% osmium tetroxide, embedded in Vestopal W, and sections were stained with lead hydroxide. Such cells differ in shape and size from signet-ring cells. They are ovoid, diminished in size, and the cell surface has become indented in all planes of the cell. The intercellular space is expanded with concentrations of collagen fibers in close association with the cell surface. These changes are presumed to be mechanical events associated with loss of lipid from the cell. Subcellular changes include the appearance of an extremely large number of pinocytotic vesicles and cytoplasmic vesicles similar in appearance, membrane-bound dense bodies, five-layered membranous structures, vesiculated bodies, and areas of flocculent material. Mitochondria and nuclei appear to be similar to their counterparts in signet-ring cells. Observations are discussed with relation to ultrastructural changes reported in other studies in which adipose cells were depleted of fat by acute starvation or experimental deprivation of insulin. It is suggested that intracellular structural changes are probably associated with adaptive alterations in the metabolism of the cell.
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    Quantitative studies of areal boundaries in myelin preparations of the human cerebral cortex (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 313-319 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: With the aid of a simple photometer, myelin preparations (Weigert-Pal 50 m̈ thick) of six different regions of the human cerebral cortex were scanned. For each region a plot of optical density as a function of the distance from the surface of the cortex was obtained along a number of neighboring vertical lines. The validity of the concept of sharp areal boundaries was questioned on the basis of these data, and it was found that the cortical architectonics must be interpreted much less strictly than heretofore, and it should be realized that sharp boundaries between some areas do not exclude continuous gradations between others.
    Additional Material: 6 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091470302
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    The chromosomes of the ovary of the human fetus (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 295-311 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The chief purpose of this paper is to show that the human fetal ovary is a rich source of large actively dividing cells. The material consisted of the ovaries from five stillborn, morphologically normal human fetuses; 150 mm negro; two, 160 mm white; an 800 gram white; and a term white. The ovaries of the first three fetuses were removed within several hours after birth; those from the last two were removed at autopsy, wrapped in cellophane, placed in an insulated container and mailed to me. These were prepared for study about 36 hours after autopsy. Smears and squashes were made according to modern methods, but no colchicine was used. The nuclei of the ova were very tough and did not respond well to the usual hypotonic technics. Best results were obtained from fragments of the ovary suspended in blood, smeared, dried in the air and stained with Wright's blood stain. Qualitative studies were made of the chromosomes, their shapes during prophase and metaphase of meiosis; and quantitative studies were made by planimetry of the areas of the squashed chromosomes as they occurred in enlarged photographs. The planimeter measurements of areas of squashed haploid chromosomes showed remarkable agreement in percentages of the total chromosome area included within each of the accepted seven classes of chromosomes from nucleus to nucleus. Sample karyotypes were made from nuclei of the five fetuses, but no unequivocal absolute numbers could be counted, because of the twisted condition of the chromosomes and the difficulty in identifying the smallest ones.
    Additional Material: 2 Tab.
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    URL: http://dx.doi.org/10.1002/ar.1091470211
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  • 125
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    The locking mechanism of the hip joint (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 321-324 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This study is based upon observations made upon the hip joints of 12 embalmed cadavers. Windows were made into the joints and the effects of extension and flexion of the femur, produced both actively and passively, were noted. Particular attention was paid to associated movements. Use was made of x-rays as well as direct observation.It was determined that, as the femur extends it abducts and medially rotates; a terminal medial rotation takes up the last of the slack in the iliofemoral and ischiofemoral ligaments. The locked position therefore is brought about by these three movements. There is no evidence of any medial displacement or translation of the femoral head on extension, as is commonly stated to occur. The passively extended femur also abducts and tends to rotate medially whereas the flexed femur laterally rotates and falls into a position about midway between abduction and adduction. The same general effects are reproducibile in the skeleton articulated in such a way as to leave hip motion practically unhindered. This would indicate that the ligaments play a passive role, restricting motion within physiological limits. The shape of the acetabulum and the direction toward which it faces, together with the topography of the articular surface of the head of the femur, are no doubt responsible for the associated movements.
    Additional Material: 6 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091470303
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    Bone development in Japanese quailThis work was performed under the auspices of the Atomic Energy Commission and was partially supported by United States Public Health Service Grant No. A-4225 Met., Research Fellowship No. DPD-12,985, and the Atomic Energy Commission (At(11-1)-787). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 325-335 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The development of the long bones of Japanese Quail was studied histologically and microradiographically at different post-hatching periods from birth to one year of age. At the level of the mid-shaft, the woven bone of the neonatal animal becomes thicker by rapid periosteal growth and becomes consolidated by the deposition of bone within large vascular spaces throughout the first month of life. Continued periosteal growth and formation of osteons is most rapid during the second and third month, and the mature architecture of the cortex  -  primary haversian bone  -  is established at the end of this period. Osteon formation is more progressive in the tibiotarsus and tibia than in the femur. Replacement osteons are established by remodeling endochondral bone incorporated into the metaphysés near the endosteum, but these deposits delimited by cement lines do not seem to be remodeled to any significant degree. Bizarre resorption cavities attributed to osteolysis were frequently observed in highly mineralized interstitial lamellae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470304
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    Bloodstreams and the formation of the interatrial septum in the anuran heart (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 355-357 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Patterns of blood flow have been observed at several critical stages in the development of the frog heart. Shortly after the onset of circulation (Shumway stage 20) two inflowing streams were noted to cross in the sinus venosus and then continue through the atrium, parallel to each other. With the development of the hepatic return (stage 24) the right stream becomes much larger and its course diverted into the area that will become the definitive right atrium. The smaller left stream is then noted to flow around the right stream with the development of a spiralling of the streams. The left stream now leads into the area which will become the left atrium. This is the hemodynamic situation as the interatrial septum forms; the septum forms between the streams. Experimental and histological evidence indicate that the interatrial septum is formed by a molding action of the bloodstreams on the tissues of the atrial wall.
    Additional Material: 3 Ill.
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    Comparative anatomical and neurohistological observations on the tongue of the marsupialsA part of this work was supported by a research grant from the Educational Ministry of Japan and was read at the twenty-third anatomical meeting of Kanto-district, Tokyo, October, 1961. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 337-353 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Macroscopic and neurohistological observations of the red, gray and tree kangaroo and wombat's tongues are described. On the dorsum, three circumvallate papillae, foliate papillae (gland-duct type), fungiform papillae and filiform papillae are observed. In the wombat, the vallate papillae are shaped like a “lotusnut.” Its summit is broadened, rough, and reaches the level of the dorsal surface. The papillae of the kangaroo are shaped like a “walnut” and are situated below the dorsal surface of the tongue. The vallate papilla is occupied with abundant nerves, thin non-myelinated and thick myelinated fibers, and ganglion cells, multipolar and unipolar. In the upper area of the wombat's papilla, however, there is a demarcated thin layer of non-innervated connective tissue. Therefore, taste buds are located in nearly the whole wall of the papilla in the kangaroo, but only in the lateral wall in the wombat, closely associated with the subgemmal nerve plexus. Foliate papillae of gland-duct type, which connect with the serous glands, have many taste buds innervated with thin fibers from the periductal nerve plexus. Also in this region there are many ganglion cells. This gland-duct type may be regarded as the primitive form of the common foliate and vallate papillae; i.e., foliate papillae may be developed from a linear gathering of its anlages, vallate ones from a circular gathering and bellshaped vallate form from an atypical type of the circular gathering. Taste buds may serve as a chemoreceptor for gland secretion in the tongue because their position does not exhibit any suitable form to receive the sense of taste. Richly innervated fungiform papillae contain a few taste buds, but poorly innervated ones have none in the upper epithelium. Filiform papillae are of a vascular nature. In the apical region of the tongue Vater-Pacinian corpuscles of simple type are found.
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    Dissection of the human brain as a method for its fractionation by weightSupported by U.S.P.H. Grant H-7047. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 359-366 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Twenty human brains were weighed as fresh specimens and for varying periods of time following fixation in 10% formol. Meninges and blood vessels were removed, the brain stem was trimmed uniformly and a final total cleaned brain weight was thereby obtained. Ten brains (group I) were specially dissected to determine the respective weights of eight brain subdivisions. Ten fixed brains (group II) were boiled for 20 minutes, then refixed in formol for 30 days. Group II specimens were then dissected into the same eight subdivisions.The use of standardized procedures and meticulous dissection yielded surprisingly uniform fractionation of the specimens in both groups I and II. This study indicates that precise gross dissection can be used as an accurate method of subdividing the human brain by weight.
    Additional Material: 4 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091470307
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    A histochemical study of the toad urinary bladderThis study was supported in part by the John A. Hartford Foundation, Inc. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 367-377 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histochemical methods for the demonstration of enzyme activities and carbohydrates were applied to the bladder of the toad, Bufo marinus. The three cell types in the mucosa (ordinary epithelial cell, goblet cell, and mitochondria-rich cell) were found to be distinctive with the methods used. Dehydrogenase enzyme activities were highly concentrated in the mitochondria-rich cells. Membrane-associated ATPase activity was found in the basal cell-membranes of the mucosal cells, where active sodium transport is thought to occur. The potentialities of the various cell types for active electrolyte transport are discussed.
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    URL: http://dx.doi.org/10.1002/ar.1091470308
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    The embryonic heart subjected to radarWith the aid of NIH Grant no. HE03565-06 and Grant from Rome Air Development Center, Air Research and Development Command, U.S.A.F. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 379-385 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: It is known that microwaves can damage tissue but the cause is poorly understood, e.g., can tissue be damaged in the absence of undesirable heat levels? To answer this question 106 isolated 72 hour embryonic chick hearts were subjected to radar waves at a frequency of 24,000 megacycles, a wave length of 1.25 cm and exposures of 478, 297, 167 and 74 mw/cm2 for lengths of time varying between a few seconds and three minutes. Electrocardiograms were taken as a continuous run before, during and after radar treatment. The hearts were planted in blood plasma on the surface of saran sheet and microwaves were directed through the sheet at the heart. Where necessary a stream of cold air was used to offset undesirable elevation of heat. At exposures of 478 and 297 mw/cm2 damage was swift and devastating. No conclusion seemed justified. However, at an exposure of 167 mw/cm2 it was possible to prevent elevation of temperatures above 38°C. Significantly the hearts showed damage in the ECG, i.e., shortening of the QT interval, increased height and breadth of the T wave and the appearance of a large U wave. Finally at 74 mw/cm2 it was possible to control heat merely by maintaining an ambient temperature below 25°C. Of twenty-five hearts so exposed, all showed ECG changes mentioned in the previous paragraph. The conclusion seems justified, that radar waves can damage tissue at exposures which do not raise the temperature to a harmful level.
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    URL: http://dx.doi.org/10.1002/ar.1091470309
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    A study of valves in the arteries of the rodent brainSupported by grant B-3901 from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, U.S.P.H.S. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 407-413 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This study is based on the cerebral arteries of 15 rats, 4 white mice, 2 Syrian hamsters and 3 guinea pigs. Elevated areas of tissue formed by the intima were stained metachromatically by cresyl violet in the rat, mouse and Syrian hamster, however none were found in the guinea pig. All areas of metachromasia were associated with a branching of the artery. These protuberances varied from rudimentary to typical valves. These protuberances in the mouse and hamster in general were more rudimentary than in the rat. In the rat there were from 40 to 79 areas of metachromasia. These arteries had a well developed internal elastic membrane separating the base of the valve from the pars media.
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    URL: http://dx.doi.org/10.1002/ar.1091470312
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    Abnormalities of pulmonary and other vessels in rat fetuses from maternal pteroylglutamic acid deficiencyAided by grants from the American Heart Association and the U. S. Public Health Service (HE-7029 and AM-841). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 397-405 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Maternal pteroylglutamic acid (PGA or folic acid) deficiency from the ninth to eleventh days of gestation produced in rat fetuses a variety of congenital abnormalities of the pulmonary and other vessels. These included single pulmonary artery, absence of the ductus arteriosus, single coronary artery, stenosis of the pulmonary trunk, persistent truncus arterious, and termination of the pulmonary veins in the right atrium or left anterior vena cava. Study of young PGA-deficient embryos showed a number of these anomalies in the course of development. Many of the abnormalities encountered resembled those occurring in man.
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    URL: http://dx.doi.org/10.1002/ar.1091470311
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    The effect of trypan blue on the serum proteins of the fetal ratSupported by research grant AM-05603-03 from the National Institute of Metabolic Diseases, Public Health Service, U. S. Department of health, Education, and Welfare. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 387-395 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Pregnant rats were injected intraperitoneally with a teratogenic dose of trypan blue (14 mg/100 g or 20 mg/100 g body weight) on the eighth day of gestation. Fetal blood was collected from control and experimental fetuses on the twentieth day of pregnancy. Serum was obtained from pooled blood samples of two to three fetuses. Paper electrophoresis was carried out in a Spinco model R system using barbital buffer at pH 8.6. The paper strips were subsequently stained with bromphenol blue and their density measured in a Spinco Analytrol to determine the relative concentration of each component. Total protein was measured in a Bausch and Lomb Serum Protein Meter. The predominant malformations seen in abnormal fetuses were apparent anophthalmia, 59%; hydrocephalus, 37%; and exencephaly, 19%. Other malformations were noted but with less frequency. Twenty-day fetuses from trypan blue treated mothers had a significantly lower total protein concentration (1.50 g/100 ml) than control fetuses (1.95 g/100 ml). A comparison of the absolute protein concentration of the serum fractions revealed significant differences between control and experimental fetuses in beta globulin, alpha-1 globulin, and albumin. In each instance the absolute concentration was less in the fraction from fetuses of trypan blue treated mothers. Fetal gamma, alpha-2, and alpha-3 globulins were not affected by the maternal treatment.
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    Intraneuronal capillary (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 415-421 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Male rabbits, subjected to transection of the facial nerve, were narcotized and fixed by a two-step perfusion procedure with a modified Heidenhain's Susa solution. The autopsy was delayed four hours or more. Serial sections of the rhombencephalon were stained with periodic acid-Schiff and gallocyanin.The course of a capillary through the perikaryon of three facial motor neurons is established beyond doubt by the study of companion sections with series of photomicrographs. The capillary is only partly in contact with the cytoplasmic membrane in its passage through the neuron.This form for neuronal blood supply must be regarded as extremely rare. Previously, it has been unequivocally depicted in a single large pyramidal neuron of the human cerebral cortex.
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    URL: http://dx.doi.org/10.1002/ar.1091470313
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    Investigations on the lateral nasal gland of the rat (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 443-455 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A gland lying in the lateral wall of the nasal cavity of the rat has been described and identified as the “lateral nasal gland.” The gland cups the outer aspect of the alveolar bone of the upper incisor root, and lies between it anteriorly, and the alveolar bone of the root of the first molar posteriorly. It is bounded by the hard palate ventrally, the infraorbital fissure laterally and the nasal mucosa, medially and dorsally. The gland consists of serous acini, the secretion granules of which are rich in PA-Schiff positive material. These acini are clearly distinguished from the mucous-secreting nasal mucosal glands which lie in the mucosa and border the acini of the lateral nasal gland. The acini of the lateral nasal gland are drained by intercalated ducts into striated ducts which anastomose to form the principal excretory duct. The latter pursues a long tortuous course beneath the mucosa of the lateral nasal wall to open into the nasal vestibule near the external nares.
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    URL: http://dx.doi.org/10.1002/ar.1091470402
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    The pars distalis of the female rabbit hypophysis: An electron microscopic studyThis investigation was carried out during the tenure of a Postdoctoral Fellowship from the Rockefeller Foundation. Supported in part by U.S.P.H.S. grants AM-04394 and GM-03784 and in part by a grant from the Josiah Macy, Jr. Foundation. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 469-497 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: New Zealand virgin rabbits were used in this study. Normal males and castrated, thyroidectomized and recently mated females formed the control groups. Correlation with the light microscopical appearance using the method of alternate thin and thick sections, correlation with the control glands, and comparison with the descriptions in the rat, were used as criteria for the identification of five different types of secretory cells in the pars distalis. Two types of “acidophiles” were found, the more numerous and conspicuous having secretory granules of a maximum diameter of 380-400 mm̈ (growth hormone-producing cell), and a second type with granules of 600-800 mm̈, very seldom seen in the virgin rabbit but increasing in number and granulation after mating (Prolactin-producing cell). Two types of “basophiles” that correspond to the “thyrotrophes” (angular shape, granules of 150 mm̈ in diameter) and “gonadotrophes” (rounded shape, granules of 280-300 mμ), were also identified. In addition, a peculiar large cell with characteristic mottled cytoplasm and very few granules was tentatively identified as a “basophile” in the process of regranulation. Its functional significance was discussed. A stellate cell having fibrillar material and no secretory granules within its cytoplasmic processes, found between parenchymal cells and approaching basement membranes, was tentatively identified as a supporting element. In addition to the description of the fine structure and possible functional significance of the different cell types, some features as cilia, desmosomes, intranuclear fibrillar material, as well as vacuolization of cells in normal glands were also discussed.
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    Relationships of the common femoral artery (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 169-170 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The relationships of the femoral artery to the anterior superior spine, the pubic symphysis, and the public tubercle were measured in 100 adult males. The average distance from the pubic tubercle to the femoral artery pulsation was 4.5 cm, from the symphysis pubis to the femoral artery pulsation was 7.7 cm, and the position of the femoral artery on a line between the symphysis and the anterior superior spine averaged its mid point. From a clinical point of view, the femoral artery is most easily located along the inguinal ligament at a point between two and three finger breadths from the pubic tubercle.
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    URL: http://dx.doi.org/10.1002/ar.1091450207
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    American Association of Anatomists. Seventy-sixth session; Georgetown University School of Medicine, April 9, 10, 11, 1963. Officers, abstract, demonstrations (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 197-376 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450213
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450301
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    The brachiocephalic artery in the dog with special reference to the arterial supply of the esophagus (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 1-5 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Two direct branches of the brachiocephalic artery are frequently present in the dog. These are described in 33 dogs and their incidence recorded. One supplies the lower cervical trachea and esophagus and the other the thymus gland and sometimes the pericardium. Suggested names are “Tracheoesophageal” and “Thymopericardial” branches of the brachiocephalic. The embryology of the blood vessels of the esophagus is discussed and the identification of the tracheoesophageal with a secondary anastomotic vessel is considered most likely. Occasional branches from the brachiocephalic artery in man are reviewed. The Arteria Thyroidea Ima seems to bear the closest relationship to this vessel described in the dog. The value of this study in relation to heart-lung preparations and to experimental surgery of the esophagus is suggested.
    Additional Material: 2 Ill.
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  • 142
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    Influence of the hair growth cycle on the glyceride content of whole mouse skinThis work was supported by the United States Public Health Service Training Program in Anatomical Sciences, 2G-582 (C1). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 39-42 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In order to examine the glyceride content of whole mouse skin during the hair growth cycle, adult male C57 Black mice (C57BL/6J) were plucked of hair in a region of the mid-dorsum in order to initiate synchronous growth of new hair. Samples of whole skin were removed from each of three different mice on various days following plucking. Stages of the hair growth cycle were ascertained by examining microscopically a portion of each sample. The remaining piece of each sample, weighing approximately 225 mg, was minced, frozen with dry ice and weighed. Following this, each sample was ground in sand with a mortar and pestle and then extracted with ethanol-ether, cleared by centrifugation and assayed for esterified fatty acids.This investigator found that during anagen the glyceride content of samples of whole mouse skin is nearly twice that found in telogen. It is possible that such cutaneous glycerides are major energy sources for the proliferation of hair, as well as for the development of the resting follile. On the other hand, the same factors which determine active hair proliferation may be responsible for glyceride accumulation under these conditions, and the two events otherwise could be unrelated.
    Additional Material: 2 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091450106
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  • 143
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    The calcified zone (basal layer) of articular cartilage of rabbits (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 73-87 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In the mammalian embryo, the articular end of a long bone consists of a mass of fetal cartilage which undergoes transformation into two types of tissue as the animal ages: The hyaline cartilage surface of the adjacent joint; and the bone of the ossific nucleus of the epiphysis. The junction of these two areas, the calcified zone (or basal layer) of the articular cartilage, was studied in the distal femur of 110 albino rabbits of various ages by: tritiated thymidine autoradiography; routine histologic staining and mitotic counts; special stain for glycogen; and special stain for calcium (murexide).In the immature rabbit (under two months) the cartilage cells are arranged in columns and there is evidence of active proliferation. In its most basal portion adjacent to the vascular tufts of the epiphyseal nucleus, the cells are hypertrophic and contain glycogen. The intervening matrix bars are calcified. It is apparent that, at this age, endochondral ossification, indistinguishable from that at the epiphyseal plate, is occurring.In the older rabbit (age four months) proliferation, columniation, and glycogen content are minimal, and the basal layer of cartilage is diffusely calcified. Proliferation is intense in and about the capillary loops and a thin layer of bone surrounds the capillary.In the adult (over six months) rabbit, calcification and ossification predominate. No proliferative activity is noted. Apparently growth has ceased completely or is so slow as to be unmeasurable by available techniques.
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  • 144
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    A comparison of autoradiographic and alizarin techniques in the study of bone growth (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 101-113 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Actively growing rats and rabbits received a single intraperitoneal injection of radioactive calcium (2.5 - 10 μc/100 gm) or alizarin red (50 - 100 mg/kg). Contact autoradiographs and gross, macerated dry alizarin specimens were prepared. In addition some alizarin specimens were sectioned serially, without prior decalcification, and the results of the various techniques were compared to determine if morphologic appearance were in agreement.Many similarities were found in corresponding regions of the radioactive calcium and alizarin preparations which included the tibia, cartilaginous joints of the skull base, the bones of the vault, the olfactory fossa, tympanic bulla and the malar process of the maxilla. In every instance the findings were in agreement, particularly in relation to the pattern of deposition and resorption in the growth of these regions, and the results were confirmed by reference to histologic control material.It was concluded that radioactive calcium and alizarin red are deposited similarly in growing bones, including those of the skull, and the results which can be obtained by the use of the two substances are fully complementary.
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    URL: http://dx.doi.org/10.1002/ar.1091450113
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  • 145
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    Dynamic condition of proteins in the visual cells of rats and mice as shown by radioautography with labeled amino acids (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 157-167 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The behavior of proteins in retinal rods was examined by injecting various labeled amino acids (methionine-S35 and -H3, tyrosine-, leucine-, and arginine-H3) into rats and mice, which were sacrificed at different time intervals between 10 minutes and 30 days. The retina of these animals was then radioautographed.Within minutes after injection of any one of the listed amino acids, a radioautographic reaction appears over the inner segment of the rods. This region of the cell is therefore a site of protein synthesis. Since this synthesis may be seen at any time of the day, it must be a continuous phenomenon.At 24 hours after injection, the radioautographic reaction appears over the junction of the inner and outer segments, and at 1.5-4 days, over the outer segment. Hence, the recently synthesized protein progressively migrates from the inner, toward and into the outer segment.Analysis of the decay of the specific activity in the inner segment reveals that two categories of proteins are synthesized there. One is a slowly turning over protein, presumably catabolized in situ and referred to as “sedentary.” The other is a fast turning over protein, which migrates into the outer segment and is referred to as “exportable”. The exportable protein may be opsin.
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    URL: http://dx.doi.org/10.1002/ar.1091450206
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  • 146
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    Cellular differentiation in the anuran pronephrosSupported by an institutional grant of the American Cancer Society. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 179-182 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Ribonucleic acid (RNA) is detectable histochemically by means of methyl green pyronin staining (controlled with ribonuclease) in the cytoplasm of the proximal tubules of the frog (Rana pipiens). This is seen at Shumway stage 23 when the proximal tubules become differentiated from the remainder of the tubular complex. RNA levels remain high during the process of pronephric differentiation, dropping when this process is completed. The onset of specific renal functions (phenol red transport; protein resorption) during the period of high RNA levels raises the question of the role of RNA in the development of renal function as well as cellular differentiation. Histochemical events accompanying differentiation in the pronephros (periodic acid-Schiff staining of the brush borders and the appearance of protein resorption droplets) are similar to those found in differentiating meso- and metanephric kidneys. Mitochondria in the undifferentiated pronephros are found to be granular in form by vital staining with Janus green B and with iron hematoxylin staining. These organelles do not consolidate into rodlets as found in differentiated meso- and metanephric kidneys but remain in their original granular form, as demonstrated by the techniques noted above. Granular mitochondria have been demonstrated in the differentiated pronephros of a month old tadpole.
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    URL: http://dx.doi.org/10.1002/ar.1091450210
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  • 147
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    Chemocytological studies on a sudanophile substance in parathyroid cells of the toad (Bufo vulgaris japonicus) (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 377-383 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A sudanophile lipid was demonstrated in the parenchymal cells of the toad (Bufo vulgaris japonicus) parathyroid gland in specimens taken at the end of hibernation. A series of histochemical staining methods and extraction techniques for lipids were applied to the parathyroid tissues in an attempt to characterize chemocytologically the sudanophile substance. From its chemocytological properties such as sudanophilia and nile blue sulfate and acid hematein stainability, the substance was concluded to consist primarily of glycerides and phosphatides. The cytophysiological significance of these lipid moieties in the parathyroid cells was discussed in relation to the hibernation of the amphibian species.
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  • 148
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    Structural changes in the ovaries of IF mice due to age and various other states: Demonstration of spontaneous pseudopregnancy in grouped virginsPart of a thesis presented for the degree of Ph.D., University of Leeds. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 439-447 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ovaries of inbred IF mice were studied at ages ranging from 16 to 70 weeks in four experimental groups: virgins grouped in fours, virgins rendered anosmic by removal of the olfactory lobes, females kept with vasectomized males (i.e. pseudopregnant) and post-breeding females.The ovarian structural changes taking place with age are described, pointing out the differences in findings with other strains of mice. Further, two structures termed “anovular buds” and “dark-staining epithelial cells” have been distinguished as separate entities arising from invaginations of proliferating germinal epithelium, especially in old ovaries.The ovaries of virgins were similar to those of pseudopregnancy group of mice and showed a large number of corpora lutea. In both groups, uterine endometriosis occurred and the estrous cycles were of a pseudopregnancy type. Further, good lobular development in the mammary glands of the virgins is seen as in the pseudopregnancy group of mice. These similarities furnish evidence for the occurrence of spontaneous pseudopregnancy in grouped IF virgin mice.When spontaneous pseudopregnancy is prevented by removal of the olfactory lobes, the ovaries become precociously senile. The atrophic ovaries, have a loose folded germinal epithelium around the shrunken ovary, contain many atretic follicles and are conspicuously lacking in intact corpora lutea. The uteri are thin and threadlike. The lobular acinar development of the mammary glands is inhibited.
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  • 149
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    A textbook of comparative endocrinology, Aubrey Gorbman and Howard A. Bern, 468 pages, 7¼″ × 9⅞″, $12.50, John Wiley & Sons, Inc., New York, 1962 (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 473-475 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450311
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  • 150
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    Development of parabiosis intoxication in rat parabiontsSupported by grant from U.S.P.H.S. National Cancer Institute. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 503-511 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The development of parabiosis intoxication, primary symptoms of which are anemia of one animal and concomitant hyperemia of the other, was sequentially followed in Holtzman (Sprague-Dawley)  -  Charles River (Sprague-Dawley) parabionts. Hemoglobin and hematocrit determinations, RBC, reticulocyte and WBC counts were done on blood removed from pairs by cardiac puncture. In addition bone marrow total nucleated cell counts were done, systolic blood pressure measurements were taken and cross circulation rates were studied with Cr51 tagged erythrocytes. Intoxication developed rapidly in these distantly related pairs about 10 days after union and terminated in death or breakdown of the union by 21 days. The anemia, which was not limited to one or the other partner, was accompanied by reticulocytosis and normal nucleated bone marrow cell counts indicating no suppression of marrow function. The anemic partner also showed total white cell counts elevated over those in the hyperemic partner at 13 days after union. The partner destined to become hyperemic showed elevated systolic blood pressure concomitant to the change in erythrocyte values suggesting that no causal relation exists between blood pressure and the development of intoxication. Cross circulation rates tested with Cr51 tagged erythrocytes showed slowing of circulation evident as early as nine days after parabiosis. Some pairs maintained circulation rates similar to controls for as long as 15 days, but in the majority cross circulation had virtually ceased by this time.
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  • 151
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    The salivary glands and salivary bladder of the nine-banded armadilloThis study was supported by U. S. Public Health Service grant D-1663. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 513-519 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histochemical studies of armadillo salivary glands reveal mucous acini as the predominant secretory unit of the submaxillary and parotid glands. The acidic carbohydrate moiety of the salivary mucin is mostly sialic acid since Vibrio cholera neuraminidase (sialidase) markedly reduces the alcian blue reaction in the acinar cells. Morphologically, the acini of the submaxillary gland resemble the long mucous tubules of carnivore zygomatic glands whereas the parotid gland corresponds more closely to the seromucous classification. In the submaxillary gland specialized afferent ducts terminate in a storage organ called the salivary bladder. Contents of the bladder consist of a highly viscous sialomucin plus varying amounts of acidophilic material which is negative to the periodic acid-Schiff and alcian blue reactions. The bladder itself is composed of a wall made up of cuboidal epithelium, skeletal muscle and connective tissue and it is emptied by means of a single efferent duct which leads to the oral cavity. Parotid gland striated ducts are characterized by simple columnar epithelium containing considerable amounts of glycogen in the basal two-thirds of the cells.
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  • 152
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    The mouse uterine surface epithelium during the estrous cycle (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 541-548 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Four groups, each containing six three-month old virgin mice of the CBA strain have been used. The four groups represent different stages of the ovarian cycle, namely proestrus, estrus, metestrus, and diestrus.The uterine tissues have been both fresh frozen and fixed in a Champy solution. The fresh frozen specimens have been sectioned in a cryostat, postfixed, and used for fluorescence, polarization, and phase contrast microscopy or stained with Sudan Black, osmic acid, toluidin blue, or the PAS-technique. The specimens, fixed in the Champy solution, have been embedded in PEG and sectioned for analysis of osmophilic substance.The lipid granules of the surface epithelium are numerous in the whole cell during diestrus. In estrus, only a small basal rim of granules is left. The lipid granules are neither autofluorescent nor anisotropic.The PAS-positive secretory products are most prominent during estrus, and consist during this stage of cytoplasmic granules, a layer on the cell surface, and an irregular substance in the lumen. In diestrus, only a few cytoplasmic granules are observed.The basement membrane is thick and undulating in diestrus and metestrus, but thin and even in estrus. The present investigation has not revealed any vacuolar degeneration of the uterine epithelium nor any fading and disappearance of its basement membrane in late estrus and in metestrus as noticed by earlier workers.
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  • 153
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    A modified rabbit's ear chamber high-power high-resolution studies in regenerated and preformed tissuesSupported by grants from the National Heart Institute of the U. S. Public Health Service (H-5724) and from The Swedish Medical Research Council.Mechanical design in collaboration with Messrs. I. Jonsson and P.O. Ågren. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 533-540 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Vital microscopic studies in capillary flow, cell structure and cell function with the aid of the ear chamber technique demands special mechanical and optical design of the chamber, if the full resolving power and ability of structure identification of the light microscope is to be utilized to the limit.In order to fill these requirements a new type of ear chamber has been designed, based on the principle of a tissue section between cover glass and glass slide.The metal parts are made of titanium, which is highly tolerable to the tissue and as transparent, parallel windows ordinary cover glass and glass slide have been used.Special attention has been paid to the immobilization of the chamber in the microscope.The exposed tissue has a long lifetime thus enabling long term studies.
    Additional Material: 9 Ill.
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  • 154
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    Adrenergic synaptic vesicles in the anterior hypothalamus of the ratThis work was supported by grant B-1549 of the National Institutes of Health and the Consejo Nacional de Investigaciones Cientificas y Técnicas, Argentina. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 521-531 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: After formaldehyde perfusion a small area of the anterior hypothalamus was extirpated, identified neuroanatomically and studied under the electron microscope.The preparative technique consisted in refixation of the piece in 1% osmium tetroxide for two hours, immersion in 2% uranyl acetate and embedding in Epon 812. Sections were stained with lead acetate.The main areas comprised in the tissue were the nucleus hypothalamicus anterior, nucleus periventricularis inferior and anterior hypothalami area.In the neuropiles of these regions varicose axons containing neurotubules and granular vesicles are observed. There are also numerous nerve endings containing typical synaptic vesicles in addition to some having a dense granule of reduced osmium. Measurements demonstrate that there are two different populations of vesicles with means of 510 Å and 1,300 Å respectively.The possible significance of the granular vesicles is discussed and related to the high content of catecholamines in this region of the CNS. The possibility that these nerve endings may synthesize and store more than one transmitter substance is also discussed. The wide variety of vesicles found in axons and synaptic endings of the anterior hypothalamus is also considered as supporting a unified theory of neurosecretion postulated by one of the authors.
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  • 155
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    Autoradiographic investigation of cell proliferation in the brains of rats and cats (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 573-591 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Cell proliferation in the brains of rats and cats was investigated autoradiographically. Two young adult rats were injected intraperitoneally with 2 mc of thymidine-H3 and killed after a two weeks' exchange period. Two adult cats were injected intraventricularly with 0.5 mc of thymidine-H3 and killed one week later. Labeling of cell nuclei in the brain, presumed to reflect DNA turnover and cellular proliferation, was investigated. In the rats, some neuroglia cells were found labeled in all parts of the brain, suggesting a low rate of glial proliferation. In addition, circumscribed small regions with numerous labeled neuroglia and microglia cells were seen in several brain regions, suggesting the occurrence of local glial proliferative reactions in these presumably normal brains. A few apparently labeled neurons were seen in the neocortex, and a proliferative region of granule cells was identified in the dentate gyrus of the hippocampus. In the cats labeling of glia cells was highest in the midline region, near the point of injection of the radiochemical, with a gradient of decreasing number of labeled cells both laterally and in the anteroposterior direction of the neuraxis. Neurons with apparently labeled nuclei were observed in the midline cortex bilaterally in both animals. These results indicate that glia cells can multiply in the brains of young adult rats and adult cats and they support the possibility that new neurons may be formed in forebrain structures, both in rodents and carnivores.
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460101
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  • 157
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    Biological effects of freezing and supercooling. By Audrey U. Smith. 1961. 462 pages. 157 figures. 64 tables. $11.00. Williams and Wilkins, Baltimore (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 593-594 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450410
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  • 158
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    Books received (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 594-595 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450411
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  • 159
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    Spatial variations between certain cranial and cerebral structures and the anterior and posterior commissures of the living human (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 1-6 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Recorded are the quantitated empirical findings and statistical variations of spatial configurations prevalent among certain cranial and cerebral structures related to the intercommissural line as encountered in 50 stereotactically-performed, radio-opaque lateral ventriculograms of the living human. A physicomathematical technique of mensuration was devised to overcome the difficulties that regularly arise when fixed postmortem specimens are employed to study the same relationships. Clearly, the reliability of human stereotactic atlases is a function of the technique of mensuration employed.Mean length of the intercommissural line was 24.50, and Range 20.90 to 30.90 mm. Mean distance from inferiormost aspect of sella turcica to posteriormost aspect of anterior commissure was 28.30, Range 23.80 to 36.60 mm. Mean length of line from “center” of external auditory meatus to anteriormost aspect of posterior commissure was 43.36, Range from 35.2 to 49.3 mm. Mean angle formed by “line” of orbital roof and intercommissural line was 19.78° and Range, 8.50° to 29.50°. Mean angle between Reid's base line and intercommissural line was +0.04°, Range, from -9.90° to +10.20°. Mean angle between line from “center” of external auditory meatus to anteriormost aspect of posterior commissure and Reid's base line was 97.93°, Range 85.40° to 120.45°.The least variable relationships of the six studied were the distances (a) from the external auditory meatus to the posterior commissure and (b) from the floor of the sella turcica to the anterior commissure.
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    The ultrastructure of capillaries and arterioles of the hamster dental pulpThis investigation was supported by U.S.P.H.S. research grant D-1620 from the National Institute of Dental Research, National Institutes of Health. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 549-571 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastructure of capillaries and arterioles of the hamster dental pulp has been studied. Pieces of the incisor pulp were fixed in 1% OsO4 buffered with 0.14 M veronal acetate, embedded in epoxy resin and studied in an electron microscope. The basic cytoplasmic organization of endothelial cells confirmed observations on blood vessels of other organs made by previous investigators. A large number of intracytoplasmic fibrils were found in many endothelial cells, and their presence was discussed in relation to earlier reports on the contractility of endothelial cells. Previous observations on the structural details of the intercellular region of the endothelium were confirmed and elaborated upon. The manner in which the cytoplasmic flaps of adjoining cells were oriented indicated that, if the integrity of the capillary wall was maintained, only cells with capacity for ameboid movement could creep through the region. Thus they were thought to play a role as an effective barrier against the passage of red blood cells. Numerous micropinocytosis and pinocytosis vesicles were found in association with plasma membranes. The significance of their structure in the transport of materials across the capillary wall is discussed. The fine structure of the pericyte resembled that of the fibroblast. Portions of plasma membranes of adjacent smooth muscle cells in the media of arterioles were brought together closely and resembled attachment zones.
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    URL: http://dx.doi.org/10.1002/ar.1091450408
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    Cholinesterases in the tongue of the potto (Perodicticus Potto)This work was supported by grants from the United States Public Health Service - RG-2125 (C12), and USPHS D-1215. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 7-15 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The tongue has three circumvallate papillae, arranged in a triangle ahead of the foramen caecum. Gustatory buds are found only on the walls of the vallate papillae and at the surface of the fungiform papillae. The gustatory cells contain acetylcholinesterase; the sustentacular cells contain no such enzymes. A subepithelial network of nerve fibers, containing acetyl-and butyrylcholinesterases is parallel to the surface of the tongue and extends into the connective tissue cores of all papillae. Numerous pleomorphic end organs are found below all four types of papillae. These abound in acetyl-and butyrylcholinesterases. The dorsal subepithelial blood vessels contain butyrylcholinesterase, and small amounts of acetyl-cholinesterase. The ventral aspect of the tongue has fewer nerve fibers and end organs than the dorsal surface does. The nerve fibers to the serous glands of von Ebner, and particularly those to the mucous glands contain considerable acetylcholinesterase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460103
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  • 162
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    Testosterone suppression of mesenchymal alkaline phosphatase activity and lympho-epithelial nodule formation in the bursa of fabricius in the embryonic chickSupported by research grant HE-04061-05 (HEM) from the National Institutes of Health, Bethesda, Md. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 23-27 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The relatively strong alkaline phosphatase activity of the subepithelial mesenchyme of the bursa during the period of lympho-epithelial nodule formation (12-15 days of incubation) and the close association of vascular channels with surface epithelium at sites of nodule formation suggest the possible role of these factors in induction and/or development of these nodules.Experimental inhibition of nodular formation and development may be accomplished by the administration of testosterone prior to the onset of this process (e.g., 12th day of incubation). One-tenth milliliter (2.5 mg) of testosterone propionate in sesame oil (Schering) was administered on the tenth, eleventh and twelfth days of incubation. Bursas from 136 experimental and 64 control embryos were removed on the thirteenth, fifteenth and eighteenth days of development, fixed in cold 80% ethanol and embedded in paraffin. Alkaline phosphatase activity was demonstrated by the Gomori's glycerophosphate procedure using incubation times of one-half, two and four hours at 37°C.Testosterone administered on the twelfth day produced a moderate decrease in alkaline phosphatase activity and markedly reduced nodule formation and subsequent development. When administered on the eleventh day, however, alkaline phosphatase activity was greatly reduced and essentially complete inhibition of nodular formation was accomplished.The possible direct inhibitory effect of testosterone on alkaline phosphatase activity (and possibly other mesenchymal cell functions) and the resulting inhibition of lympho-epithelial nodule formation during embryogenesis of the bursa of Fabricius is suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460105
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  • 163
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    Histochemical studies on the yolk nucleus in the oogenesis of Indian ReptilesThis work was carried out in the Department of Zoology, University of Gorakhpur, India. The author wishes to thank Dr. Gilbert S. Greenwald for reading the manuscript. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 17-21 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The yolk nucleus of the young oocyte of reptiles is situated in the juxta-nuclear cytoplasm. It is a homogeneous spherical mass and histochemical tests indicate that it is rich in RNA and proteins. It constitutes a center of high synthetic activity. Lipid inclusions of diverse nature and mitochondria appear in abundance in association with the yolk nucleus. Eventually the yolk nucleus disintegrates and its RNA-containing substance as well as the other inclusions are distributed throughout the cytoplasm. During yolk formation, lipid inclusions and mitochondria are absorbed by the cytoplasm but the yolk nucleus substance continues to persist among the growing yolk bodies which arise de novo from the cytoplasm. This occurs possibly under the activity of RNA-containing substance of the yolk nucleus, mitochondria and lipid inclusions.
    Additional Material: 16 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091460104
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  • 164
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    Electron microscopy of the acinar cell of the that preputial glandThis investigation was supported by U.S.P.H.S. grant AI-4039-02. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 47-59 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The rat preputial gland is a morphologically complex structure active in both lipid and protein secretion. By electron microscopy, its acinar cells contain an extensively developed endoplasmic reticulum and numerous Golgi vacuoles, where the protein secretory granules apparently arise. As the granules mature, they assume a crystalloid configuration and, after losing their surrounding membranes when the cell degenerates, are deposited in an excretory duct along with lipid and cellular debris. The granules are apparently unrelated either to mitochondria or to tonofiliments, but seem to represent a true protein secretion of the acinar cell itself.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460107
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  • 165
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460201
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  • 166
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    An electron microscopic study of the effects of reserpine on adreno-medullary cells of the syrian hamsterThis research supported in part by Anatomy Training Grant 2G-459 (C1), U.S.P.H.S. grant B-690 (C7) and in part by a grant from the Medical Research Foundation of Texas. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 29-45 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Adult Syrian hamsters were given daily subcutaneous injections of reserpine (1 mg/kg) for one or three days in order to study the fine structural changes in adreno-medullary cells. Initial alterations of fine structure in animals given one injection and sacrificed 15 hours later. Hamsters treated for three days were adrenalectomized on the left side 24 hours after the last reserpine injection. Following adrenalectomy, animals were allowed to recover for 48 or 96 hours after which the cells of the right adrenal medulla were compared with those of the left.Medullary cell changes 15 hours following one injection of reserpine included partial loss of electron opaque granules and an increase in the number of cytoplasmic vesicles and vacuoles. Medullary cells from the left adrenal glands removed following three subcutaneous injections of reserpine were characterized by a marked loss of electron opaque granules and by the presence of many vesicles and vacuoles distributed throughout the cytoplasm.Forty-eight hours following unilateral adrenalectomy medullary cells from the remaining right glands exhibited slightly electron opaque granules within the cytoplasm, each of which was surrounded by a smooth surfaced membrane. Cytoplasmic vesicles and vacuoles had decreased in number. Ninety-six hours following unilateral adrenalectomy medullary cells from the right glands showed further decreases in numbers of vesicles and vacuoles, and granules which possessed an electron opaqueness comparable to control medullary cells had reappeared within the cytoplasm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460106
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  • 167
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    On the ultrastructure of spinal nerve roots in the frog (Rana pipiens) (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 61-84 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: An electron microscopical study was made of the seventh and tenth ventral and dorsal spinal nerve roots and peripheral nerves of adult frogs, to determine whether or not tunicated and sheathed nerve fibers extend into the spinal cord and into the periphery. The nerves were exposed under urethane anesthesia, fixed in 1%, veronal acetate-buffered osmium tetroxide (pH-7.6) plus 0.495 gr/10 ml sucrose, and refrigerated over two hours. Thin cross and longitudinal sections were made and examined with a Siemens electron microscope. A few tunicated fibers were found in the peripheral nerve, but not in the spinal nerve roots which consisted of myelinated and unmyelinated (Gasser-type) axons. Therefore, tunicated and sheathed nerve fibers were restricted to sympathetic ganglia. This was the more likely, because intrinsic neurons are absent in the sympathetic, and nearly all axons are myelinated in caudal rami communicantes. It was further suggested that preganglionic fibers, after entering, and postganglionic fibers before leaving the sympathetic ganglion changed their myelin sheaths, and appeared as tunicated and sheathed fibers. No structural differences between afferent and efferent cholinergic or adrenergic fibers could be detected in spinal roots. Large vesicles with dark centers, probably containing catecholamine, and dense punctate granules, occurring in sympathetic fibers, were virtually absent in spinal root fibers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460108
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  • 168
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    Morphogenetic studies of the rabbit XXXV. Comparison of the weights and linear measurements in normal and heterozygous dwarf rabbits of race X (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 85-92 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This report presents the weights of the skeleton and 11 bones, 26 linear measurements of the bones and 17 measurements of the skull of 35 adult heterozygous (Dwdw) dwarf rabbits of race X.The female skeleton is slightly heavier but the long bones of the extremities are heavier in the males. The most varible bones are those with much cancellous bone.As percentages of total skeleton, in rabbits of the same sex, the mandible is the only bone significantly heavier in both sexes of the dwarfs. The ribs and scapula are significantly heavier in normal (dwdw) rabbits.Measurements of the bones are slightly more variable in the males. Only two of the 26 measurements are significantly longer in each sex, but as percentages of body length, 11 are significantly longer in the males and one in the females. The long bones of the extremities are generally longer and narrower in both sexes of the dwarfs.The 17 linear measurements of the skull show no significant sex differences. Six of these, as percentages of body length are greater in dwarf and none in normal females. Only two are significantly greater in dwarf males. The skull measurements are slightly larger in males and somewhat larger as percentages in the dwarfs.
    Additional Material: 6 Tab.
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    URL: http://dx.doi.org/10.1002/ar.1091460202
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  • 169
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    Studies of cartilage and osteoid arising spontaneously and experimental attempts to induce their formation in ear chambersThis investigation was supported by a research grant from the National Science Foundation. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 93-107 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Clark and Clark using a rabbit's ear chamber in which the observation space was in direct continuity with perichondrium reported cartilage arising spontaneously in more than 40% of chambers. With a chamber of different design having a very restricted relationship to perichondrium, osteoid, that is, an unmineralized bone-like tissue, appeared in 5 of 110 animals and in two of the five there were also unrelated islands of cartilage. In one additional animal osteoid developed three months after local application of continuous pressure of minute degree. In the remaining 104 animals no cartilage or osteoid formed irrespective of the experimental usage to which the chambers were put. The results are interpreted to mean that in rabbit's ear chambers cartilage or osteoid may form from precartilaginous cells resident in or derived from perichondrium but not by metaplasia of morphologically similar connective tissue cells. If a special stimulus was necessary to activiate the precartilaginous cells then the only obvious ones were friction and pressure both of very small degree but continuously maintained for long periods.
    Additional Material: 1 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091460203
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  • 170
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    On the structural peculiarities of the pituitary in some clupeoid fishes with a note on their probable evolutionary significance (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 109-115 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Hilsa ilisha has a well developed sella turcica comparable to that of Polypterus and Epiceratodus. The persistent orohypophyseal duct and parasphenoidal foramen of adult Hilsa ilisha may represent the retention of embryonic features such as those seen in Salmo trutta, Chanos chanos and Elops saurus. Since this duct is considered to be the persistent base of Rathke's pouch, its presence in adult Hilsa ilisha is an archaic feature which may be considered as the repetition of the condition observed in Polypterus, Calamoichthys and Latimeria. The presence of discontinuous orohyphyseal duct in the fry and fingerlings of Engraulis telara and Gadusia chapra suggests that it may be the remnant of an open buccal connection present during the embryonic condition. In all the specimens used in this study the hypophyseal cavity is in the form of a “tube system” restricted to the rostral pars distalis and it is formed by the constricted and separated portion of the diverticuli of the orohypophyseal canal. It is better developed in the adult Hilsa ilisha and Gadusia chapra than in Engraulis telara. This reduction in the prominence of the duct tends towards the reported condition in the “primitive teleosts” the trout and the eel. Though basically the pituitary of the clupeoid fishes described are of the typical teleostean type, the orohypophyseal duct and the hypophyseal cavity in the form of a “tube system” are distinctly chondrostean features. The presence of these features in different degrees of expression in these forms and the expression of ductile and tubular structure in the fry of Chanos chanos, Salmo trutta and Elops saurus together apparently provide a continuous range of variations from the typically chondrostean to that of the higher teleostean type where cavities and ducts are totally absent.
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    URL: http://dx.doi.org/10.1002/ar.1091460204
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  • 171
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    Microcirculation in the islets of langerhans of the mouseSupported by grants from the United States Public Health Service (H-3944) and the Louis G. Block Fund, The University of Chicago. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 117-123 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A technique for the study of microcirculation in living islets, using quartz rod and cinephotomicrography, is presented, together with results of a study of insular microcirculation. With this technique, conditions are standard, results are reproducible and the findings are recorded permanently. The pancreas, bathed constantly in Locke-Ringer's solution at 37°C, is lifted with the spleen from the body, supported on the tip of Knisely's hollow-tipped fused quartz rod, and the lobules are separated gently. Circulation in the transilluminated islets, which are pale yellow, spherical or ovoid bodies with a distinctive vascular pattern, is studied with the biobjective, binocular microscope. For cinephotomicrography, the camera is aligned over one eyepiece of the microscope and the film is exposed at 64 frames per second, using a 750 watt projection bulb as light source. Direct anastomoses of insular and acinar capillaries are not observed. Blood flow in the islets of the anesthetized mouse is rapid and constant, under these conditions of observation. Intravenous epinephrine and ephedrine cause temporary interruption of blood flow in the islets, whereas nor-epinephrine slows but does not stop the circulation. Pitressin also causes slowing of insular blood flow. Insulin, glucagon, hydrocortisone, glucose, alloxan and diphenylthiocarbazone have no acute effect upon the insular microcirculation. A possible relation between the circulatory effect and the hyperglycemic effect of epinephrine and ephedrine is suggested.
    Additional Material: 2 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091460205
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  • 172
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    Estrogen-induced changes in the golgi apparatus and lipid of the uterine epithelium of the rat in the normal cycleAided by a grant from the National Science Foundation. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 139-143 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The Golgi apparatus of the uterine epithelium of the rat starts to increase in size during the transition from diestrus to proestrus and continues to enlarge until it reaches its maximum development in estrus. Regression takes place during metestrus. The accumulation of phospholipid at the base of the epithelial cell, characteristic of diestrus, decreases in quantity as the Golgi apparatus increases in size and reappears as the Golgi apparatus regresses. Both of these changes are responses to circulating estrogen and form part of the complex series of reactions by means of which this hormone exercises its control over reproductive function.
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    URL: http://dx.doi.org/10.1002/ar.1091460207
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  • 173
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    On the presence of valves in the rat cerebral arteriesSupported by grant B-3901 from the National Institutes of Health, U.S.P.H.S. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 145-147 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Valves were observed in the muscular cerebral arteries of the rat at the level of the optic chiasm in each of the ten adult animals examined. These paired valves were formed by folds of the intima. They were frequently associated with a branching of the artery. Part of the well formed internal elastic membrane separated the base of the valve from the media, while some very thin elastic fibers spread through the tissue forming the valve. The area of the valve was stained metachromatically by cresyl violet and was sharply differentiated from the remaining non-metachromatic arterial wall. The internal elastic membrane was intensely stained by fuchsin paraldehyde, PAS, orcein and silver diammine.
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    URL: http://dx.doi.org/10.1002/ar.1091460208
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  • 174
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    Cell proliferation and displacement in the adrenal cortex of young rats injected with tritiated thymidine (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 125-137 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The origin and fate of cells within the growing adrenal cortex have been studied autoradiographycally in young rats injected with thymidine-H3 and sacrificed at intervals between one hour and ten weeks after injection.Cell proliferation (DNA synthesis and mitosis) was greatest in the zona glomerulosa, dropped off progressively deeper in the cortex, and was negligible in the inner fasciculata and reticularis. The shorter cell generation times in the glomerulosa, compared to the other zones, were due mainly to a decrease in duration of the G1 period of the cell proliferative cycle, although a slight diminution in the length of G2 + mitosis was also detected. The average duration of DNA synthesis was not appreciably modified.Growth of the cortex was achieved through peripheral addition of new cells produced by mitosis in the outermost regions of the gland. As the cortex thickened, some labeled cells within these outer layers were gradually displaced to progressively greater distances from the medullary surface. Since these cells remained within the zone of rapid proliferation, they continued to divide, thereby diluting their radioactivity. Other labeled cells were gradually displaced out of the proliferative regions towards the medullary surface, and into zones which did not support cell division (inner fasciculata and reticularis). In consequence, heavily labeled cells were ultimately restricted to the innermost zones.It was suggested that as cells are displaced within the growing adrenal cortex they encounter changing microenvironments which influence not only proliferative activity, but presumably enzymatic pathways of steroid synthesis as well.
    Additional Material: 5 Ill.
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    URL: http://dx.doi.org/10.1002/ar.1091460206
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    The development and hormonal response of the autotransplanted interpubic joint in miceSupported by United States Public Health Service grant GM-04433-08. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 149-163 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ventral portion of the immature pelvis of 12-day-old female mice, consisting of the interpubic cartilage and the angles of the pubic bones, was excised and either autoimplanted into its original pelvic site or autotransplanted to the thoracic region. Half the number of mice with pelvic implants and half with thoracic transplants received subcutaneous injections of estrogen and relaxin prior to necropsy. All were sacrificed at 63 days of age.All the pelvic implants and the majority of thoracic transplants were present at necropsy. The grafts from the untreated mice were similar to the intact pubic symphysis ofa 63-day-old mature mouse both in size and morphology. The grafts from the hormone-treated mice had undergone a pregnancy-type response of cartilage transformation to ligamentous tissue and resorption of the medial ends of the pubic bones. The possible significance of the cells of the interpubic joint in its response to hormones is discussed.
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    URL: http://dx.doi.org/10.1002/ar.1091460209
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  • 176
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460301
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  • 177
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    A method for demonstrating subserous lymphatics with hydrogen peroxideSupported by research grant HE-05480-03 of the National Institutes of Health of the United States Public Health Service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 165-171 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The visualization of the subserous lymphatics of various organs is rapidly accomplished by the topical application of hydrogen peroxide. As the peroxide reacts with a natural inclusion of the lymph, presumably catalase, the vessels are spontaneously inflatedwith free oxygen. This method is much easier to use than injection techniques as fresh material, catheterization of the vessels, or tissue puncture are not required.
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    URL: http://dx.doi.org/10.1002/ar.1091460210
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  • 178
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    Editorial (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 191-192 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460302
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  • 179
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    The effect of D-L ethionine on the pancreas of normal and pregnant hamstersThis work was supported by ONR contract 2754 (00) and (01). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 89-95 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A series of 49 normal male and female adult hamsters, nearly equally divided as to sex and 37 pregnant animals received ethionine subcutaneously or intraperitoneally. Normal animals were given 1.0, 0.7 or 0.4 mg per gram of weight per day over a period of 4 to 14 days. Pregnant animals received either 1.0 or 0.7 mg, beginning at different intervals during gestation: from the third to sixth; on the eighth, of from the tenth to twelfth days, the course ranging from two and one-half to 15 days. Normal females were more sensitive than males. Among the latter, the 1.0 mg dose produced degeneration of exocrine tissue in ten days with no deaths, while in normal females, 0.7 mg gave similar results with little mortality or liver pathology. In pregnant females, the drug had adverse effects, vaginal bleeding and high mortality resulting when administered on the eighth day or later. From 11 survivors, only two litters were obtained, no damage being found in either maternal or neonatal pancreases. Pregnant animals started on the third to sixth day with the 0.7 mg dose tolerated it well. However, all but one of 17 expected litters died long before birth. The pancreases from the new-born were normal with only slight damage found in the maternal pancreas. The route of administration was of no consequence.
    Additional Material: 1 Tab.
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    URL: http://dx.doi.org/10.1002/ar.1091450111
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  • 180
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    Atlas of histopathology of the skin, G. H. Percival, George L. Montgomery, and T. C. Dodds. xi + 490 pages, 525 colored photomicrographs, $24.50. E. & S. Livingston, Ltd., Edinburgh and the Williams & Wilkins Co., Baltimore, second edition, 1962 (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 115-116 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450114
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  • 181
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    The decidual cell response in the golden hamster (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 97-99 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Decidual cell responses elicited by mechanical uterine trauma applied at two loci in one or both horns two full days after sterile mating were studied in 70 pseudoprgnant hamsters. The antimesometrial response was overt near the middle of the fourth 24-hour interval post coitus and the mesometrial response appeared one day later. The response was maximal during the seventh and eighth 24-hour intervals post coitus, necrosis commenced near the end of the eighth and total separation of the necrotic mass from the endometrium was complete one full day later. Glycogen appeared in the antimesometrial region before the mesometrial response was overt and later filled most of the cells of both regions. Sheathed arteries were prominent at the utero-mesometrial junction.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091450112
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  • 182
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    Pigment granule formation in slate, a coat color mutant in the mouseScientific contribution no. 12 of the Agricultural Experiment Station, University of Connecticut. Contribution no. 84 of the Institute of Cellular Biology. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 146 (1963), S. 365-372 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Slate (slt) is an autosomal recessive mutation which affects the pigment granule attributes, size, shape and number, in the cortex and medulla of the hair, in the epithelial melanocytes of the eye, and in the neural crest-derived melanocytes of the uveal tract and Harderian gland. Pigment granules are reduced in number in all of the pigmented sites, they are unusually large, and they are quite irregular in shape. In addition, there is a tendency of slt granules to clump together in the medulla of the hair.Studies of pigment granule genesis in the epithelial, uveal and Harderian gland melanocytes indicate that the reduced number of granules found in the presence of slt is due both to the synthesis of fewer melanin granules, and to the fusion of individual granules into progressively larger pigmented bodies. Granule size thus increases at the expense of granule number. Since granule shape becomes more irregular as granule size increases, it appears that the effects of slt on pigment granule size, numberand shape are inter-related.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091460410
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  • 183
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    The postnatal development and differentiation of the boundary tissue of the seminiferous tubule of the ratThis investigation was supported by a grant from the Medical Research Council of Canada. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 243-259 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The morphology of the boundary tissue of the seminiferous tubule of the rat has been investigated in testes from animals aged from birth to four months. In the adult, the boundary tissue consists of four layers: (1) an inner non-cellular layer comprising a network of collagen fibrils sandwiched between two basement membranes (2) an inner cellular layer of flattened cells showing many of the characteristics of smooth muscle, including intracytoplasmic filaments and micropinocytotic vesicles, (3) an outer non-cellular layer containing scattered colagen fibrils and associated usually with a single basement membrane and (4) an outer cellular layer, component cells of which contain no fine filaments. At birth, the seminiferous tubule rests upon a basement membrane which separates it from a layer of low cuboidal cells. External to this, there is a narrow intercellular zone containing scattered fibrillar material and a region consisting of numerous processes of mesenchyme cells. By ten days postnatal, four definite layers are established due to the differentiation of an outer cellular layer of flattened cells from the mesenchyme, and intracytoplasmic filaments have made their appearance within the inner cellular layer. In subsequent stages there is progressive thinning and specialization of the cellular layers and increased fibril content within the non-cellular layers. By 22 days postnatal the boundary tissue appears virtually adult in morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470208
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  • 184
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470301
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  • 185
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    Illustrated physiology. By Ann B. McNaught and Robin Callander. 287 pages. $6.75. Williams and Wilkins Company, Baltimore. 1963 (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 439-439 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470316
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  • 186
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    Extrinsic nerves of the chicken's uterus (shell gland) (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 431-437 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Eighty-six White Leghorn chickens were examined in a study of the neural components of the hen's uterus (shell gland). All nerves supplying the uterus were found to originate from only the left side of the body.Contributions from the sympathetic nervous system were supplied by the hypogastric nerve, which is the direct continuation of the aortic plexus, coursing along the hypogastric artery to the uterus. The parasympathetic pelvic nerves originate from the pelvic visceral rami of spinal nerves 30  -  33. The several ganglia and numerous nerves situated along the left pelvic nerve compose the left pelvic plexus. Nerves emanating from the left pelvic plexus course along the middle uterine and posterior uterine arteries to their termination on the uterus. The ganglia situated on the right pelvic nerve are not considered to constitute a right pelvic plexus, as they make no direct contribution to the reproductive system.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470315
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  • 187
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    Muscles alive  -  their functions revealed by electromyography. By J. V. Basmajian. 1962. XI + 267 pages, 126 figures. $8.50. The Williams & Wilkins Company, Baltimore (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 440-441 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470317
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  • 188
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    Books received (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 441-442 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470318
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  • 189
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    Ultraviolet microbeam irradiation of vesicle-like bodies in agranular interphase cells cultured from Triturus viridescensThis investigation was supported by a PHS Research Grant no. GM-09397, from the Division of General Medical Sciences, U. S. Public Health Services. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 423-429 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In flattened cells cultured from the heart of Triturus viridescens, cytoplasmic vesicles possessing a decreased refractive index were observed in the vicinity of the nucleus. The vesicles displayed a bubbling phenomenon when viewed by dark medium phase contrast microscopy and recorded by time lapse photography. Usual fat stains failed to reveal the vesicles in fixed preparations. DaFano's and Aoyama's methods employing silver imparted a brown-yellow color to the vesicles, but because the cell nucleus also stained the same color, no identification could be advanced.Heterochromatic microbeams of ultraviolet light focused into the vesicular complex caused swelling and fusion of the vesicles, followed by regression in size until they could no longer be seen. Cytoplasmic irradiation adjacent to and at relatively great distances from the vesicles failed to evoke this reaction from the vesicles. An interesting side effect was recorded in the nucleus: a diminished granularity of the chromatin. This effect was likened to previously recorded cytoplasmic irradiation effects; that of nuclear pyknosis in eosinophils, and spindle destruction in early mitotic cells. Irradiation of fat droplets caused none of these effects. Further studies are aimed at defining the nature of these vesicles, with emphasis on the vesicles being pinocytotic vesicles, endoplasmic reticulum or Golgi vesicles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470314
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  • 190
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963) 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470401
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  • 191
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    Vascular networks from explants of human synovialis in vitroSupported in part by grant AM-02520 from the National Institute of Arthritis and Metabolic Diseases, NIH Bethesda, Maryland, and by private funds from Southwestern Clinic & Research Institute, Inc. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 525-531 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Explants of human synovialis obtained surgically were cultivated under dialysis membrane in the multipurpose Rose chamber and in Eagle's medium enriched with 20% pooled human cord sera. Within 24 hours monocytes and lymphocytic cells emerged from the majority of explants while spindle and stellate cells appeared later on the second and third days of culture. A monolayer of cells developed in which active mitosis was observed. Between 12 to 15 days, fingerlike projections of cells adjacent to the explants branched out between the cover glass and the monolayer of mesenchymelike growth and by the twenty-fifth day had developed into anastomosing networks eventually ranging in length from 1.2 to 3.2 mm. Ciné and still phase photomicrographs decumented findings. Vascular networks developed in vitro in 85% of the total 80 Rose chambers examined over an average period of 58 days. Minute vessels, patent for only short distances, were lined with endothelial cells characterized by slender elongated nuclei and with two or three small nucleoli. In contrast, flanking fibroblasts were considerably larger with clear oval nuclei containing conspicuous nucleoli. Differential stains demonstrated reticular fibers and distinct bundles of collagen lying along the vessels, particularly in the area adjacent to the fragment. In the study of rheumatoid arthritis, where vascular lesions are known to occur, it is possible that such preparations may provide favorable test objects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470407
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  • 192
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    The vascularization of adrenal transplants in the rat and the effect of X-irradiationThis investigation was sup orted (in part) by a contract, AT (30-1)-1254, with the United States Atomic Energy Commission, and U. S. Public Health Service grant C-3989. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 533-545 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Vascularization of subcutaneous (ear) and mesenteric adrenal autografts, homografts, and x-irradiated autografts was studied microscopically through visualization of small blood vessels by intravascular precipitation of lead chromate. Vascularization of autografts in both sites begins on the third day after transplantation with a surface network of small vessels. Vascular buds penetrate the graft on the fourth day. On the seventh vascularization is complete. Vessels penetrate along regenerated adrenocortical fasciculi. Later, large vessels supplying the network around the graft are prominent and venous sinuses exist near the surface. Vascularization of subcutaneous homotransplants follows the same qualitative course but is chronologically irregular, delayed one or more days in most cases. On the second day an inflammatory vascular reaction occurs around the wound in the ear. Generally, vessels are finer, less well injected than in autografts. Mesenteric homografts, however, are vascularized like mesenteric autografts. X-irradiation of adrenals in vitro with 2,000 r prior to autografting also produces chronological irregularity and retardation of vascularization, up to 28 days after subcutaneous transplantation, but only during the first 12 days in mesenteric transplants. Except for reduction in size, from the thirteenth day on, x-irradiated mesenteric transplants are like non-irradiated controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470408
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  • 193
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    Polyploidy and parthenogenesis in the root-knot nematode Meloidogyne arenariaContribution from Departments of Genetics and Plant Pathology, North Carolina Agricultural Experiment Station, Raleigh, North Carolina, U.S.A. Published with the approval of the Director of Research as paper no. 1607 of the Journal Series. This study was supported by a grant of the National Science Foundation (no. GB-599). (1963)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 113 (1963), S. 489-499 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051130309
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  • 194
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    The thymus in mice of strain 129/J, studied with the electron microscopeThis work was supported in part by grants rg-3784 and rg-7176 from the national institutes of health, united states public health service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 1-33 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120102
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  • 195
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    Morphological and histochemical studies of experimentally enlarged and atrophied salivary glands of ratsThis work was supported in part by a research grant (D-992) from the national institute for dental research. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 65-79 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120105
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  • 196
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    New observations on the structure of the pacinian corpuscle and its relation to the perineural epithelium of peripheral nervesSupported by grant B-1914 of the national institute of neurological diseases and blindness and by funds from anatomy training grant 2G-305 of the national institutes of health, division of general medical sciences. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 97-109 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120107
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  • 197
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    Masthead (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963) 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120201
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  • 198
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    Influence of certain purines and pyrimidines on the development of the down featherThis investigation was supported in part by a research grant, RG-3813(C5), from the division of research grantsand fellowships, national institutes of health, U. S. public health service, and by the industrial science research institute of iowa state university. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 153-167 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120203
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  • 199
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    Cutaneous branches of the dorsal (primary) rami of the cervical nervesThis investigation was supported in part by research grant B-302 (C8) from the division of research grants and fellowships of the national institute for neurological diseases and blindness, U. S. public health service. (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 169-180 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120204
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  • 200
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    A correlated histochemical and biochemical study of glycogen storage in the rat placentaSupported by U.S.P.H.S. grants rg-3298(8); RG-6859(A). (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 112 (1963), S. 215-241 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001120207
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