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  • 1995-1999  (1,114)
  • 1985-1989
  • 1810-1819
  • 1995  (1,114)
  • Engineering  (787)
  • Genetics  (327)
  • 1
    ISSN: 1432-5233
    Keywords: Maturity-onset diabetes of the young (MODY) ; Genetics ; Diabetes mellitus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Genetic linkage studies of families with earlyonset type 2 diabetes have facilitated the identification of diabetes-susceptibility genes. In order to assess the feasibility of using linkage approaches to identify genes responsible for the development of type 2 diabetes in Japanese subjects, we examined our clinical records for multigenerational families suitable for genetic studies. We identified 16 families in which at least one subject was diagnosed with type 2 diabetes before 25 years of age. Seven of these families had a pattern of inheritance consistent with a diagnosis of maturity-onset diabetes of the young (MODY) and nine families showed a complex pattern of inheritance of type 2 diabetes with transmission of diabetes-susceptibility genes from both parents. The glucokinase and mitochondrial tRNALeu(UUR) genes were screened for mutations in at least one affected subject from each family in order to assess the contribution of mutations in these genes to the development of the diabetes. No mutations were found, which suggests that the diabetes in these families resulted from mutations in other genes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 90 (1995), S. 380-388 
    ISSN: 1432-2242
    Keywords: Genetics ; Breeding ; Sorghum bicolor Zea mays
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The objective of this study was to use restriction fragment length polymorphisms (RFLPs) to determine the genetic location and effects of genomic regions controlling plant height in sorghum. F2 plants (152) from the cross CK60 x PI229828 were used. Genomic and cDNA clones (106) identified 111 loci distributed among ten linkage groups covering 1299 cM. Interval mapping identified four regions, each in a separate linkage group. These regions may correspond to loci (dw) previously identified by alleles with qualitative effects. Also, these regions identified in sorghum may be orthologous to those previously reported for plant height in maize. Gene effects and gene action varied among genomic regions. In each region, PI229828 alleles resulted in increased plant height. Each region accounted for 9.2–28.7% of the phenotypic variation. Positive, additive effects ranged from 15 to 32cm. Tallness was dominant or overdominant and conferred by alleles from PI229828 for three quantitative trait loci (QTL). At the fourth QTL, PI229828 contributed to increased plant height, but short stature was partially dominant. One digenic interaction was significant. The presence of a PI229828 allele at one region diminished the effects of the other region. A multiple model indicated that these four regions collectively accounted for 63.4% of the total phenotypic variation. The utility of this information for germplasm conversion through backcross breeding is discussed.
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  • 3
    ISSN: 1432-0533
    Keywords: Primitive neuroepithelial tumor ; Desmoplastic small cell tumor ; Brain tumor of infancy Immunocytochemistry ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe a case of a desmoplastic brain tumor which was initially resected from the right fronto-temporal region in a 2 year-old boy. This nodular, calcified tumor was vascularized by the internal carotid artery and the middle meningeal artery branches. Grossly, it contained several mucoid cysts. Light microscopy showed cords or nests of small cuboidal cells surrounded by a loose connective tissue and desmoplasic areas containing fibers and spindle cells. The cuboidal cells expressed epithelial, neuronal and neuroendocrine markers. Some foci of spindle cells showed glial differentiation. The tumor recurred 16 months later and displayed some characteristics of the small cell neuroepithelial component, mitoses being conspicuous. Electron microscopy revealed undifferentiated clear cells, some containing neurosecretory granules. Karyotyping demonstrated the following formula: 〈 15 〉 46, t(8;11) (a13; q11). The chromosome 11 breakpoint was different from that described in Ewing's sarcoma. This isolated translocation has not been previously reported to our knowledge. These unusual features lead us to report this case and to discuss its pathogenesis.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 654-657 
    ISSN: 1432-1076
    Keywords: Key words Fetal development ; Brain diseases ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two female siblings with the fetal brain disruption sequence. Extensive investigation of both children failed to define a definitive aetiology but clinical and laboratory findings are consistent with a hitherto unknown storage disease. We postulate that the accumulation of a neurotoxic metabolite may be responsible for the disease phenotype observed. This is the first report of recurrence of the fetal brain disruption sequence and supports the existence of a genetic form of this condition. Previous reports have emphasized possible environmental aetiologies. Infants with fetal brain disruption sequence should be investigated exhaustively and, in the absence of definitive evidence of an environmental cause, the possibility of a genetic aetiology should be considered. In some families the recurrence risk may be as high as one in four.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1076
    Keywords: Key words Floating-Harbor ; syndrome ; Growth retardation ; Dysmorphology ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome. Conclusion The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.
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  • 6
    ISSN: 1432-1076
    Keywords: Key words Osteogenesis imperfecta ; Collagen I ; Mosaicism ; Genetics ; Recurrence risk
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Osteogenesis imperfecta (OI), a dominantly inherited connective tissue disorder, is usually caused by defects in collagen I. There is growing evidence for parental mosaicism that results in affected children born to unaffected parents. This situation poses a difficult task for the geneticist because a mosaic parent may appear clinically healthy while carrying the mutation in a fraction of her or his gonadal cells. To illustrate this problem, we report a Swiss couple whose first child was affected with severe OI. The unexpected recurrence of the disorder in the second child raised the suspicion of a recessive trait or, rather, of parental mosaicism. We identified the responsible collagen mutation in the COL1A2 gene (Gly688Ser in the α2(I)-chain) in both children and demonstrated the father to be a somatic mosaic for this mutation and to have subtle clinical signs such as soft skin and short stature that may be a result of his mosaic state.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 654-657 
    ISSN: 1432-1076
    Keywords: Fetal development ; Brain diseases ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two female siblings with the fetal brain disruption sequence. Extensive investigation of both children failed to define a definitive aetiology but clinical and laboratory findings are consistent with a hitherto unknown storage disease. We postulate that the accumulation of a neurotoxic metabolite may be responsible for the disease phenotype observed. This is the first report of recurrence of the fetal brain disruption sequence and supports the existence of a genetic form of this condition. Previous reports have emphasized possible environmental aetiologies. Infants with fetal brain disruption sequence should be investigated exhaustively and, in the absence of definitive evidence of an environmental cause, the possibility of a genetic aetiology should be considered. In some families the recurrence risk may be as high as one in four.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1076
    Keywords: Floating-Harbor syndrome ; Growth retardation ; Dysmorphology ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abstract The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome. Conclusion The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 46 (1995), S. 394-399 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Malignes Melanom ; Genetische Instabilität ; Genetik ; Syndrom der dysplastischen Nävi ; Xeroderma pigmentosum ; Key words Malignant melanoma ; Genetic instability ; Genetics ; Dysplastic nevus syndrome ; Xeroderma pigmentosum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Exposure of the skin to ultraviolet irradiation is an important risk factor for the development of malignant melanoma, with UVA possibly playing an important role. Hereditary factors are also relevant. In the dysplastic nevus syndrome a genetic instability has been shown by different methods. In xeroderma pigmentosum the DNA repair defect is thought to be responsible for the high incidence of malignant melanoma. Frequent and non-random changes in certain chromosomes have been demonstrated in melanoma cells. These might contain sequences that control melanoma growth or melanoma suppressor genes. Especially the short arm of chromosome 9 is thought to contain one of these genes. This hypothesis is supported by a genetic linkage analysis in melanoma families and the demonstration of a germ line deletion of the locus 9p21 in a patient with eight primary melanomas. Changes in known tumor suppressor genes and oncogenes have also been reported in melanoma, but no consistent sequence of genetic events is known.
    Notes: Zusammenfassung Die Exposition der Haut mit ultravioletten Strahlen ist ein wichtiger Risikofaktor für die Entwicklung eines malignen Melanoms. Möglicherweise spielt hierbei UVA-A eine besondere Rolle. Daneben sind hereditäre Faktoren von Bedeutung. Während beim Syndrom der dysplastischen Nävi eine genetische Instabilität mit verschiedenen Methoden nachgewiesen wurde, wird bei Xeroderma pigmentosum der DNA-Reparaturdefekt für die hohe Melanominzidenz verantwortlich gemacht. In Melanomzellen sind überzufällig häufig karyotypische Veränderungen in bestimmten Chromosomen gefunden worden. Diese enthalten möglicherweise Melanomwachstumsregulierende Sequenzen oder Melanom-Suppressorgene. Insbesondere der kurze Arm des Chromosoms 9 steht in Verdacht, eines dieser Gene zu enthalten. Diese Hypothese wird auch unterstützt durch eine genetische Kopplungsanalyse an Melanomfamilien und dem Nachweis einer Keimbahndeletion des Lokus 9p21 bei einer Patientin mit 8 primären Melanomen. Veränderungen an bereits bekannten Tumorsuppressorgenen oder Onkogenen sind ebenfalls in Melanomen beschrieben worden, ohne daß jedoch eine konsistente Reihenfolge von genetischen Ereignissen bekannt wäre.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 90 (1995), S. 146-149 
    ISSN: 1432-2242
    Keywords: Capsicum chinense ; Resistance gene ; Genetics ; Pepper ; Tomato spotted wilt virus ; Tospoviruses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Pepper (Capsicum chinense Jacq.) has been reported to be an important reservoir of resistance genes to tomato spotted wilt virus (TSWV). The genes for TSWV resistance present in three C. chinense lines (‘PI 152225’, ‘PI 159236’ and ‘Panca’) were investigated for allelism. All resistant lines were crossed with each other. Parents, F1, backcrosses and F2 populations (including reciprocals) developed from those crosses were mechanically inoculated with a highly virulent TSWV isolate. Susceptible C. annuum cv ‘Magda’ was used to check inoculum virulence. Fifty plants of the F1 hybrids; ‘Magda’ x ‘PI 152225’, ‘Magda’ x ‘PI 159236’, and ‘Magda’ x 'Panca, were also inoculated with the TSWV isolate. The resistance response in all C. chinense sources was associated with a localized, hypersensitive-like reaction that was phenotypically expressed as a prompt formation of large local lesions accompanied by premature leaf abscission. All F1 generations presented a final score of resistant; indicating that the expression of resistance to TSWV is conditioned by a dominant gene regardless of the source. The absence of segregation for resistance to TSWV that was observed in all generations of the crosses between C. chinense lines indicated that either a tightly linked group of genes exists or that the resistance is governed by the same single major gene (probably the already described Tsw gene). Previous reports have indicated that the Tsw gene is not effective against tospovirus members of serogroup II, i.e. tomato chlorotic spot virus (TCSV) and groundnut ring spot virus (GRSV). In the assay described here, all of the C. chinense lines showed, after mechanical inoculation, an identical susceptibility response to the TCSV and GRSV isolates.
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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 90 (1995), S. 707-713 
    ISSN: 1432-2242
    Keywords: Mineral stress ; Nutrient efficiency ; Aluminium tolerance ; Inheritance ; Genetics ; Breeding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The Brazilian tropical adapted soybeans contains, in addition to superior morphological characters, genetic factors for tolerance to cultivation in acidic, mineral-stressed soils. However, the selection process for these hindrances has been empirical, and information on the genetics of mineral element uptake by the plant is necessary. The objective of this investigation was to identify the mode of inheritance for the absorption of phosphorus, potassium, calcium, magnesium, iron, aluminium, manganese, zinc and copper in a 9 × 9 diallel cross. General combining ability (GCA) was higher than specific combining ability (SCA), with the exception of copper, manganese and zinc, indicating predominantly additive effects. The ratios of GCA/SCA varied between 3.4 (calcium) and 8.5 (magnesium). The regression of covariance (Wr) on variance (Vr) showed that the additive-dominance model explained the genetic differences in this germ plasm. However, the detection of overdominance could be related to possible heterozygosity in the parental varieties for mineral absorption. Broad-sense heritability values were higher than narrow sense heritability values for aluminium, iron, potassium, calcium and magnesium, being in the range of 67.9–86.9% and 42.0–56.6%, respectively. This is an indication that soybeans can be further improved to efficient utilisation of nutrients and to tolerate toxic factors in the soil.
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  • 12
    ISSN: 1432-2072
    Keywords: Opioid ; Genetics ; Self-administration ; CXBK/ByJ ; Reinforcement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It is commonly thought thatμ-receptors play an important role in the reinforcing effects of opioids. In the present study, inbred strains widely divergent in CNS opiate receptor densities were used to investigate the influence of genetic variation in receptor concentration on opioid-reinforced behavior. In particular, the CXBK/ByJ mice were used as an investigative tool because of their significantly lower number of CNSμ opioid receptors. The behavioral pharmacology of opioids in theμ-deficient CXBK/ByJ mice was compared to other commonly used inbred mouse strains, C57BL/6J and BALB/cJ, and the opiate receptor rich CXBH/ByJ mice. Operant opioid reinforced behavior, opioid-induced locomotor stimulation, analgesia and respiratory depression were investigated in all four inbred strains. To assess the acquisition and maintenance of opioid reinforced behavior, oral self-administration of the potent benzimidazole opioid, etonitazene, was determined using an operant fixed-ratio schedule of reinforcement (FR 8). Acquisition of etonitazene-reinforced behavior was established in all four strains including theμ-deficient CXBK/ByJ mice. However, there were significant genetic differences in the amount of drug intake during the maintenance of opioid-reinforced behavior and extinction behavior following vehicle substitution. For example, drug intake was significantly greater in the BK versus BH mice during the maintenance phase and an extinction burst was seen in the BH but not the BK mice following vehicle substitution. Thus,μ-receptor density may not account for individual variability in the acquisition of opioid-reinforced behavior under these conditions. Sensitivity to etonitazene-induced respiratory depression, stimulation of locomotor activity and analgesia were unrelated to drug intake during self-administration sessions across these four inbred strains. These data indicate that inherited differences in CNSμ-opiate receptor concentrations do not affect acquisition of etonitazene-reinforced behavior.
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  • 13
    ISSN: 1432-2072
    Keywords: Cocaine ; Quantitative trait loci ; Seizure ; Recombinant inbred strains ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Among inbred mice, genetic factors mediate differences in sensitivity to the convulsant properties of cocaine; however, the gene(s) underlying cocaine's effects have not been identified. To help elucidate the gene(s) responsible for cocaine seizure susceptibility, we used recombinant inbred-quantitative trait loci (RI-QTL) analyses to identify chromosomal loci associated with cocaine-induced seizures. RI-QTL analyses seek to identify associations between a quantitative measure of a particular phenotype and one or more previously mapped marker genes across a panel of RI strains. This report describes an RI-QTL analysis of cocaine seizure susceptibility among 26 BXD RI strains. These strains showed a skewed, bimodal range of seizure susceptibility which could be the result of one or more modifying genes acting in concert with a major gene to influence cocaine sensitivity. Correlating the percent seizures displayed by each strain following 60 mg/kg cocaine with chromosomal marker data for these strains revealed a number of significant correlations clustered in two regions on chromosomes 12 and 6. This is the first identification of putative chromosomal loci associated with a cocaine-related phenotype and should facilitate identification of the gene(s) underlying cocaine toxicity and other cocaine-related phenotypes.
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Sexual plant reproduction 8 (1995), S. 129-132 
    ISSN: 1432-2145
    Keywords: Sex control ; Disomic segregation ; Dioecy Kiwifruit ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The sex segregation ratio was checked in bi-parental families of Actinidia deliciosa (2n=6x=174) obtained by crossing four females (A12, Mo3, Br4, Hw1) with two males (T2, M1) and one fruiting male (M3h, subandroecious) according to a factorial mating design. The M3h fruiting male was also selfed. The sex ratio was checked in maternal families of A. kolomikta (2n=2x) and A. chinensis (2n=2x) as well as in A. deliciosa. Seedlings of both diploid species took 3–4 years to progress beyond juvenility, whereas a noticeable number of seedlings from biparental crosses of A. deliciosa involving A12 and Hw1 as seed parents were still non-flowering after seven growing seasons. Open-pollinated families of both diploid and hexaploid species as well as most families from biparental crosses showed a sex segregation ratio approaching 1∶1. Subandroecious lines with different degrees of ovary and pistil development appeared in proportions of 0–4.2%, depending on the cross, but only 6 of the 2567 male vines checked were capable of setting fruit. No case of self-fertility or apomixis was detected among 1866 bagged female vines. Selfed M3h progenies gave only female and male phenotypes in a ratio of 1 female to 3 males. No off-type vines were found among these progenies. The same disomic sex segregation ratio seems to be operating at different ploidy levels in the genus Actinidia. Since selfed fruiting males produced both female and male individuals, the male sex appears to be the heterogametic one. Such evidence indicates that a monofactorial system based on one or more linked genes or on an X/Y chromosome set must be controlling sex expression. How a monofactorial sex-determining mechanism could operate in polyploids to give a 1∶1 female: male ratio is discussed. Minor modifying gene(s) seem to be responsible for the feminization of males, and their expression appears enhanced by environmental conditions. Masculinizing gene(s) seem to be lacking in female genotypes.
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  • 15
    ISSN: 1432-1440
    Keywords: Adrenergic receptors ; Human genetics ; Restriction fragment length polymorphism ; Chromosome mapping ; Linkage ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have genetically mapped the genes encoding four human adrenergic receptors (ARs) of subtypes α1C, α2A, α2B, and β1, which are prototypic G protein coupled receptors that mediate the physiological effects of neurotransmitters, hormones, and drugs. We placed these genes onto the Cooperative Human Linkage Center (CHLC) and Genethon framework maps, within confidence intervals with greater than 1000∶1 odds. With multipoint analysis the α1C gene (locus ADRA1C) mapped to the interval between NEFL and D8S283; α2-C4, the gene encoding the α2C AR (locus ADRA2C), mapped to the interval between D4S126 and D4S62; and the α2-C10 (α2A AR)/β1 haplotype (loci ADRA2A/ ADRB1) mapped to the interval between D10S259 and D10S187. A fifth AR gene, β2, yielded significant LOD scores with markers on the long arm of chromosome 5; however, this locus (ADRB2) could not be mapped to any specific interval with odds of greater than 1000∶1. The two AR genes that are completely linked, α2-C10 and β1, were oriented on their shared 225-kb genomic fragment relative to the direction of transcription, with β1 being 5′ to α2-C10. The positioning of these genes on high-density framework maps allows them to be tested as candidates in a spectrum of diseases that might involve AR dysfunction.
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  • 16
    ISSN: 1432-1440
    Keywords: Atherosclerosis ; Hypertension ; Type 2 diabetes ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the search for new risk factors for diabetic macroangiopathy the insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme gene was studied in 237 consecutive patients (125 men and 112 women) with non-insulin-dependent diabetes. The female population showed an excess of ischemic electro-cardiographic changes or definite myocardial infarctions in the patients homozygous for the deletion [D/D; odds ratio (OR) 2.8; 95% confidence interval (CI) 1.4–5.3] and in the insertion/deletion heterozygotes (I/D; OR 1.8; CI 1.1–3.1) compared with the patients homozygous for the insertion (I/I). In the total series coronary heart disease, cerebrovascular disease, and claudication were more often observed in the patients with I/D (OR 1.5; CI 1.0–2.2) or the D/D genotype patients (OR 1.7; CI 1.1–2.6) than in those with the genotype I/I. The systolic blood pressure was lower in patients with genotype I/I (138±19 mmHg) than in those with the genotype I/D (149±22 mmHg) or D/D (150±21 mmHg; P〈0.02). The prevalence of hypertension and the median urinary albumin excretion rate also tended to be lowest in the I/I genotype patients. Multiple logistic analysis revealed that in women the angiotensin-converting enzyme D/D genotype is independently associated with coronary heart disease. Our findings suggest that variation at the angiotensin-converting enzyme gene locus is one of the factors involved in the predisposition of diabetic patients to the development of arterial disease and hypertension.
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  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 242 (1995), S. 508-511 
    ISSN: 1432-1459
    Keywords: Dystonia ; Torticollis ; Blepharospasm ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The inheritance of focal dystonias was investigated in 43 families containing 43 index cases with torticollis (n = 21), blepharospasm (n = 18) and writer's cramp (n = 4). They generated a potential population of 235 first-degree relatives, and 168 out of 179 living first-degree relatives were examined. Ten relatives with dystonia were identified in ten families. Another two parents from two of the same group of ten families were affected according to the family history. The majority of the secondary cases (six patients, five siblings, and one child) were not aware of any dystonia. The tendency for affected relatives to have the same type of dystonia as index patients was observed only for torticollis. Overall, 23% of index patients had relatives with dystonia. Segregation analysis suggested the presence of an autosomal dominant gene or genes with reduced penetrante underlying focal dystonia.
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Rheumatology international 15 (1995), S. 89-93 
    ISSN: 1437-160X
    Keywords: SLE Lupus ; BBV transformation ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Epstein-Barr-virus (EBV)-transformed lymphoblastoid B-cell lines were generated from peripheral blood lymphocytes of 55 patients with systemic lupus erythematosus (SLE) and 44 healthy relatives. All donors have previously been extensively characterized with regard to clinical, serologic, and genetic parameters. Here, peripheral blood lymphocytes and lines were characterized for cell surface antigens. Furthermore, autoantibody production and proliferation rate of the cell lines were monitored. A significant difference between patients and relatives was the lower proliferation rate of EBV-transformed cell lines of the SLE patients. All SLE cell lines are available for interested researches and can be obtained from the European Cell Bank, Salisbury, UK.
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  • 19
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 14 (1995), S. 355-364 
    ISSN: 1476-5535
    Keywords: Transformation ; Fungi ; Yeast ; Genetics ; Biotechnology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The genetic investigation of fungi has been extended substantially by DNA-mediated transformation, providing a supplement to more conventional genetic approaches based upon sexual and parasexual processes. Initial transformation studies with the yeastSaccharomyces cerevisiae provided the model for transformation systems in other fungi with regard to methodology, vector construction and selection strategies. There are, however, certain differences betweenS. cerevisiae and filamentous fungi with regard to type of genomic insertion and the availability of shuttle vectors. Single-site linked insertions are common in yeast due to the high level of homology required for recombination between vectored and genomic sequences, whereas mycelial fungi often show a high frequency of heterologous and unlinked insertions, often in the form of random and multiple-site integrations. While extrachromosomally-maintained or replicative vectors are readily available for use with yeasts, such vectors have been difficult to construct for use with filamentous fungi. The development of vectors for replicative transformation with these fungi awaits further study. It is proposed that replicative vectors may be inherently less efficient for use with mycelial fungi relative to yeasts, since the mycelium, as an extended and semicontinuous network of cells, may delimit an adequate diffusion of the vector carrying the selectable gene, thus leading to a high frequency of abortive or unstable transformants.
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical medicine and bioethics 16 (1995), S. 347-373 
    ISSN: 1573-1200
    Keywords: Genetics ; human research ; adolescence ; child ; informed consent ; decision making ; medical ethics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Philosophy
    Notes: Abstract The participation of adolescents in genetic research engenders unusual problems concerning the nature of their informed consent. In this study we analyze 70 consent documents collected from genetics investigators in the United States who conduct research with children and adolescents. We find that many consent documents do not reflect either the current or the developing ethical and legal standards for research with adolescents and that in many cases the documents are simply confusing or unclear. We make recommendations for change to reflect more adequately the changing perspective concerning the autonomous decision-making capacity of adolescents.
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  • 21
    Electronic Resource
    Electronic Resource
    Springer
    Environmental biology of fishes 43 (1995), S. 1-27 
    ISSN: 1573-5133
    Keywords: Conservation ; Extinction ; Rarity ; Biodiversity ; Breeding guilds ; Endemism ; Speciation ; Habitat degradation ; Environmental management ; Invasive fishes ; Genetics ; Ecology ; Stenotopy ; Captive propagation ; Legislation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The conservation status and factors threatening fishes worldwide are reviewed in order to introduce a series of one-page articles on ‘Threatened fishes of the world’, and to encourage the incorporation of information on threatened fishes into international conservation programmes. Information on fish extinction and threat rates are compared with those of other animal groups, and the unique characteristics of fish conservation problems are highlighted. At present 979 species of fishes are listed as threatened in the IUCN Red List and at least 36 species and three subspecies are listed as recently extinct. It is argued that these figures are probably gross underestimates and that they may mislead conservation authorities and resource users about the seriousness of the situation. Freshwater fishes may be the most threatened group of vertebrates after the Amphibia. Urgent action is required to save many narrowly endemic, stenotopic species from extinction, especially in Africa, Asia and South America. The conservation of common species that drive essential ecological processes is also important. Anthropogenic pressures, especially habitat degradation, the introduction of invasive species and pollution, on inland and coastal waters are particularly severe and many major fish communities are threatened with elimination throughout the world. The conservation of marine fishes is complicated by the fact that it is difficult to ascertain their rarity. The importance of the retention of genetic variation is highlighted, and both orthodox and innovative conservation measures are encouraged. Further research on minimum viable populations, genetics, and the factors that cause fishes to become vulnerable to extinction, is urgently required.
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  • 22
    Electronic Resource
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    Springer
    Theoretical and applied genetics 91 (1995), S. 639-646 
    ISSN: 1432-2242
    Keywords: Gene introgression ; Genetics ; Linkage ; Taxonomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The wild tetraploid (2n=28) oat species Avena magna and A. murphyi have been domesticated by having been transferred from the common oat, A sativa (2n=42), the characteristics of non-shedding spikelets glabrous and yellow lemma, and reduced awn formation. Domestication has been achieved by crossing the common oat with either of the tetraploid species and then backcrossing the pentaploid hybrids with pollen of the tetraploid wild parent. Among the BC plants obtained only a few produced some seeds. Fertile tetraploids exhibiting the domesticated syndrome have been selected for in the F2 generation. Although morphologically they were almost indistinguishable from the common oat, they were tetraploids. Wild x domesticated A. magna hybrids were vigorous and fertile. They retained their spikelets at maturity, lemma color and pubescence were intermediate between the parental lines, and awns were formed only on the lower floret of the spikelet. Each of these characteristics segregated in a 3∶1 fashion, indicating single gene control, as in the common oat. These four characteristics formed a linkage group in one F2 family and two linkage groups in the other two families. The usefulness of the domesticated tetraploids for oat research and production has been discussed. Taxonomically, the domesticated tetraploids were ranked as subspecies: A. magna ssp. domestica, and A. murphyi ssp. rigida.
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  • 23
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 74-74 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 24
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 77-94 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A two-dimensional lossy shunt TLM node is incorporated into a TLM system and adapted to model for the first time the Maxwell field equations in thin semiconductor samples. Both the characteristics of the node and the TLM system itself are fully described. By considering a parallel-plate structure containing a thin GaAs sample, driven by a voltage source, it is shown, with an example, that this TLM technique can simulate the response of non-stationary electromagnetic fields in a semiconductor to applied excitations.
    Additional Material: 16 Ill.
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  • 25
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 149-149 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 26
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 315-330 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Transmission-line laser models (TLLMs) are time-domain models suitable for the simulation of complex phenomena in semiconductor lasers. TLLMs include time-domain filters based on transmission-line stubs to model the spectral dependence of the material gain. In this paper, numerical simulations are presented which show that the accuracy of these gain models is dependent on the model's iteration timestep. Analytical formulae are derived that relate the accuracy of the filters to the timestep, filter centre frequency, and filter bandwindth. A new wideband stub filter which allows the material gain to be modelled using a larger timestep is presented. This is equivalent to a digital infinite-impulse-response filter, which is more computationally efficient than finite-impulse-response filters, and is unconditionally stable. The new gain model can improve the computational speed for simulating for multimode Fabry-Perot lasers by a factor of 10-100.
    Additional Material: 13 Ill.
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  • 27
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 383-383 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 28
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995) 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 29
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 221-232 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper describes a parallel three-dimensional finite difference time-domain (FDTD) code for electromagnetic field simulation that has been developed for the Connection Machine (CM-2). The CM-2 is briefly discussed. Then the FDTD method is reviewed using a one-dimensional example, and the extensions required for the 3-D case are outlined. The parallelization of the FDTD method is considered, and a simple analytical timing model is dervied. This model predicts the efficiency of the parallelized algorithm as a function of grain size. Some specific points relating to the implementation of the parallel FDTD algorithm in Fortrans-90 on the CM-2 are discussed. Timing data for the parallel 3-D FDTD code measured on a CM-2 is presented and compared qualitatively with the theoretical model. These results are then put into perspective for a particular computations electromagnetics problem, viz. the development of software tools for full-wave modelling of 3-D optical devices. Finally, we draw some conclusions about this work.
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  • 30
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 455-455 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 31
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 447-454 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A novel procedure for synthesizing multilayered radar absorbing materials (RAMs) is presented. The procedure uses a method for global minimization of multimodal functions of continuous variables based on simulated annealing (SA). The technique is very flexible and reliable, allowing the design of absorbing materials for any grazing or normal angles over the specified frequency bandwidth. The technique is particularly suitable for the efficient design of broadband RAMs and hence for EMC applications.
    Additional Material: 6 Ill.
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  • 32
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 187-203 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This document describes the background and motivation behind the PEPSE project. It describes separately the components which make up PEPSE, the parallel design philosophy and aspects of parallel implementation.
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  • 33
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 382-383 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 34
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 417-429 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The scattering of conducting regular polyhedrons of resonant size is studied by means of the electrical field integral equation (EFIE) and the method of moments (MoM). Two models are generated for each polyhedron, a wire grid model and a triangular patch model. Two numerical codes associated with those modelling techniques are used to obtain the radar cross section (RCS) of the polyhedrons. The calculated results are compared with the analytical results of the scattering of a perfectly conducting sphere. Practical criteria relating geometric properties of the sphere and the polyhedrons are investigated for the modelling of curved surfaces by facets in electromagnetic simulations.
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  • 35
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 431-445 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The paper presents the application of nonlinear neural optimization networks to solve the linear complementarity problem. Two different approaches are presented and investigated: one leading to linear and the second to quadratic optimization programming. The numerical results of illustrative examples are given and discussed.
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  • 36
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995) 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 37
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 3-12 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper details the use of a circuit-based EM modelling technique combined with a harmonic balance simulator used to model the radiation from the microstrip bodies comprising an active antenna circuit. The modelling approach adopted for the planar bodies in the circuit will be shown to allow the use of concurrent algorithms in order to reduce overall computational time.
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  • 38
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 13-27 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper presents an analysis of the numerical algorithms used to model microwave semiconductor devices. A comparison is made of the relative merits and features of the more popular finite difference schemes. A new generalized Scharfetter-Gummel formulation is presented which is compatible with drift diffusion and energy-transport formulations, and is suitable for implementing in two-dimensional simulations on personal computers. The treatment allows for fully degenerate semiconductors, but implementation for the nondegenerate situation is easily obtained as a special case. The convergence and stability properties of the generalized scheme are discussed. The simulation of a planar submicrometre gate length GaAs MESFET is used to illustrate the application of these algorithms.
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  • 39
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 367-379 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The behaviours of parasitic bipolar transistors are investigated by exploring the physical mechanisms of negative resistance characteristics generated in a small-sized MOSFET structure. Physical experiments and three-dimensional simulations verify the expected negative resistance characteristics. The effects of variations of device parameters such as injected substrate current levels, doping concentrations, channel widths, and physical device sizes are investigated by simulation. According to simulation results, the operation of a parasitic bipolar transistor is initiated by the injected substrate current; this explains the negative resistance characteristics occurring at low operating voltages.
    Additional Material: 13 Ill.
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  • 40
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 243-248 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Two separate exercises on a similar theme are reported. In the first, the moment-method program NEC was extensively modified in order to optimize its performance on a four-processor Cray X-MP computer. In the second exercise, the MININEC moment-method program was completely rewritten into the occam programming language so that it could be executed directly by a transputer system. The NEC exercise exploited judicious use of vectorization and alternative parallelization techniques and achieved a reduction of run times by factors of about five or more. The MININEC exercise has so far achieved only a modest reduction in run-time but it has the potential for a much greater improvement if an optimum strategy for configuring the transputer network is implemented.
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  • 41
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 277-281 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A parallel implementation of the finite difference time-domain algorithm for the analysis of planar microwave circuits is presented in this paper. For this the FDTD mesh is divided in equal-sized subspaces. Every processor of the parallel computer calculates the field in one subspace. Furthermore detailed efficiency investigations are made to predict the timing performance of the parallel FDTD simulator.
    Additional Material: 5 Ill.
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  • 42
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 293-299 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: In this paper a parallel algorithm is created for solving electromagnetic wave scattering problems. The algorithm based on the finite difference time-domain (FDTD) representation of the Maxwell's equations written in 3L Parallel Fortran for use on a transputer array.The problem simulated consists of a space (air) where a spherical dielectric scatterer is located. This space is subdivided into fine equisize meshes extending throughout the 3-D domain; the excitation wave is of sinusoidal form. Geometric decomposition is used as the principal algorithm strategy.Results are presented for the performance of the classical sequential algorithm and compared with the parallel algorithm in terms of computational speed-up.
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  • 43
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 385-398 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A typical application of numerical frequency-domain computations is the calculation of electromagnetic fields in cavities. Not only the field vectors of the desired modes, but also parameters such as the resonance frequency and, in the lossy case, the damping coefficient and the quality factor of the cavity can be obtained. This problem leads to an analytical eigenvalue equation, which can be transformed in an algebraic, complex, linear eigenvalue problem by the finite integration method.The consideration of energy losses in materials is straighforward in the analytical theory, using complex material quantities, but it is still a difficult subject area to solve a complex algebraic eigenvalue problem. Generally problems with very large, complex matrices (dimension 〉100,000) have to be solved, and no commonly applicable algorithm is known so far.This paper deals with a special variant of subspace iteration with polynomial acceleration, and some problems of the application of the complex Chebyshev polynomials are discussed. Two examples with weakly lossy cavities demonstrate the capability of the new algorithm, which is successfully applied to very large problems of up to 490, 000 real unknowns.
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  • 44
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 265-275 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Parallel algorithms for the finite difference time-domain (FDTD), the planar generalized Yee (PGY), and the finite element time-domain (FETD) methods are presented. The FDTD and the PGY algorithms are both explicit time-domain solutions of Maxwell's equations, while the PGY algorithm is based on an unstructured grid. The FETD algorithm is a semi-implicit solution of Maxwell's equations using variational principles, and thus requires a matrix inversion for every time iteration. The three parallel algorithms are based on spatial decompositions of the discrete three-dimensional problem spaces. A comparative analysis of the parallel algorithms is presented based on their memory and computational efficiency as well as their parallel efficiency.
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  • 45
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 313-313 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 46
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 381-381 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 47
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 399-416 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A non-stationary longitudinal model of a thermal two-component plasma is investigated with numerical methods based on so-called high-resolution schemes. The inhomogeneous model system is solved numerically applying a splitting method, where the homogeneous conservation laws for the electrons and ions are approximated by explicit Godunov-type schemes. Coupling of both plasma components is achieved by the electric field, which is also calculated in an explicit manner after reformulating Coulomb's law. A new numerical method is proposed for the expansion of the plasma into the vacuum. This tracking method is based on the solution of the vacuum Riemann problem and avoids the difficulties of numerical approximation introduced by the vacuum where the longitudinal plasma model is not valid. This new approach of tracking resolves sharply the plasma vacuum interface and captures this boundary very well during the temporal evolution of the model system. Two test problems show the interplay, the quality and properties of the approximation methods applied.
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  • 48
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995) 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 49
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 153-168 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: In electromagnetics, a numerical technique that finds immense application is the method of moments. This method reduces the boundary value problem containing integro-differential equations into the form AX = Y, where A is a full complex matrix, that is known and X is the unknown to be solved for the given excitation Y. In this paper, the matrix equation has been solved on various computers such as the VAX 3500, VAX 8530, Multimax 320, Alliant FX/80 and IBM 3090-600E. Two of the established methods, viz. gaussian elimination and the conjugate gradient method have been used to solve the above matrix equations. A detailed timing analysis has been done to bring out the features of various computer architectures.
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  • 50
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 233-242 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper examines the use of parallel processing techniques for the electromagnetic field analysis of multilayered microwave interconnects. These techniques are applied to a full-wave formulation using an integral equation approach in the frequency domain. In order to demonstrate the feasibility of parallelization and to assess its performance advantages, several variations of the computer code have been developed. Performance tests using domain partitioning and load balancing were conducted on a 32-processor shared-memory machine (KSR1).
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  • 51
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 249-263 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The planar generalized Yee (PGY) algorithm is an extension of the generalized Yee algorithm and the discrete surface integral (DSI) methods, which are based on explicit time-marching solutions of Maxwell's equations. Specifically, the PGY algorithm exploits the planar symmetries of printed microwave circuit devices, achieving great savings in both CPU time and memory. Since the PGY algorithm is an explicit method, it has a high degree of parallelism. To this end, a highly scalable parallel algorithm based on a spatial decomposition of the general unstructured mesh is presented. Two spatial decompositions are compared, the recursive inertia partitioning (RIP) algorithm and the Greedy algorithm. The Greedy algorithm provides optimal load balance, whereas the RIP algorithm more effectively minimizes shared boundary interface lengths. Through numerical examples, It is demostrated that the Greedy algorithm provides superior speedups. It is also demonstrated that the parallel PGY algorithm is a highly scalable algorithm.
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  • 52
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 283-291 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The finite difference time-domain (FDTD) method is a well known numerical technique that has been used to solve electromagnetic boundary value problems. However, the method requires large computational resources to solve a problem, restricting its use on sequential computers to small problems.This has led to the use of expensive supercomputers in the past to solve larger problems. In this paper we first discuss existing parallel implementations of the FDTD method. We then describe an approach to compute the FDTD equations based on distributed- memory computer architectures. Finally we evaluate a low-cost parallel implementation of the FDTD method that runs on a network of Workstations, utilizing spare network capacity.
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  • 53
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 301-312 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: In this paper, the potential use of cellular automata machines for electromagnetic field solution is investigated. Cellular automata are computational models that operate on a discrete spatial lattice, evolve in discrete time, and employ simple discrete variables. We specifically examine the lattice gas automata which use simple variables to describe particles that interact with nearest neighbours on the lattice through simple rules. They are suitable for modelling the linear wave equation in two dimensions. A benefit of the cellular automata approach is that low-cost, special-purpose digital hardware exists for their efficient evaluation. The current state-of-the-art cellular automata machine is CAM-8. Computational experiments carried out on CAM-8 are provided for problems involving plane wave interaction with perfectly conducting and dielectric media in two dimensions. The examples indicate the potential use of lattice gas automata for modelling electromagnetics and their efficient evaluation using cellular automata machines.
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  • 54
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 73-73 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 55
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995) 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 109-125 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper describes a computer program for generating finite element meshes for electron guns. Two new methods, the ‘projection’ and the ‘mesh density function’ methods, are used to generate the mesh. The new methods enable the mesh distribution to be set smothly and changed easily, and also enable the mesh distribution to be adjusted according to parameters associated with the gun configuration or by feedback from the electric field calculation. The new program, which can handle a large variety of complicated electron gun structures, has been used in conjunction with the SOGUN program which has been developed by Zhu and Munro for electron gun simulation.
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995) 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 58
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 341-356 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: A novel transmission-line model for the minority carrier transport through quasi-neutral arbitrarily doped layers is proposed. Based on detailed drift-diffusion equations, the novel TLEC includes the inductance that represents the influence of the relaxation-time term. Coupled with a object-orientated hybrid circuit simulator, the novel transmission-line model is implemented for the transient analysis of minority carrier transport. A substantial longer storage time of the minority carrier transient current at the collector end of ultra-narrow base is predicted owing to inclusion of the relaxation-time term.
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  • 59
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 151-151 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 60
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 169-185 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper describes the implementation of transmission-line matirix (TLM) method algorithms on a massively parallel computer (DECmpp 12000), the technique of distributed computing in the UNIX environment, and the combination of TLM analysis with Prony's method as well as with autoregressive moving average (ARMA) digital signal processing for electromagnetic field modelling. By combining these advanced computation techniques, typical electromagnetic field modelling of microwave structures by TLM analysis can be accelerated by a few orders of magnitude.
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  • 61
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 205-219 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: PMC-3D, a parallel three-dimensional (3-D) Monte Carlo device simulator for multicomputers is discussed. The parallel algorithm is and extension of the standard Monte Carlo device simulation model in three dimensions, that combines the stockastic Monte Carlo particle simulation method with a solution of Poisson equation for quasi-static problems, and full Maxwell's equations for microwave or electro-optic phenomena. While our implementation of the Poisson solver is based on an iterative method that uses and odd/even ordering with Chebyshev acceleration, a simple leapfrog method based upon the computational unit of Yee cell is used in a finite-difference, time-domain (FDTD) formulation to solve Maxwell's equations.The parallel algorithms were implemented on a 1024-node distributed memory nCUBE multicomputer. In this work, we present the application of PMC-3D to generate the static current-Voltage characteristics of GaAs MESFET, and to simulate photogenerated femtosecond electrical transients produced in coplanar stripline on a GaAs substrate.
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  • 62
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 51-60 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Simulators in power electronics are less developed than in other electronic fields. The main modelling methods are between the numerical simulation of semiconductor device equations that hardly simulate circuits, and equivalent circuit models that show poor accuracy. We propose the application of the bond graph techniques to model modular power semiconductor devices. Furthermore, the IGBT is a new power device which combines a bipolar transistor with a MOSFET transistor. We develop a new IGBT bond graph model. The bond graph techniques give us good primary simulation results. We present in this paper the principle and the results of this modelling method.
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  • 63
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 75-75 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 64
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 127-137 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Regular boundary integral elements are employed for the dual and complementary variational formulations of Laplace problems. The problems are defined only on the boundary as usual, but as in the manner of charge simulation method (CSM), the source terms are arranged outside the domain so that the singular integral can be avoided. The Laplace problems are analysed and the usefulness of the formulation is discussed in comparison with direct BEM. The scalar potential and electric displacement vector potential functions are used in the dual and complementary formulations, with which the upper and lower bounds of the system energy or the capacitance can also accurately be evaluated.
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  • 65
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 150-150 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 66
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 357-366 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The Transmission line modelling (TLM) technique was used to simulate the class E power amplifier. An analytical method is also used to fix the required component values to ensure the desired output performance of the amplifier. An experiment was carried out to verify the simulation result of the combined method.
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  • 67
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 1-1 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 68
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 29-49 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper describes a phase model of an induction motor based on Transmission-Line Modelling technique. Its main advantage compared to the existing TLM d-q model is the possibility of using a small part of the stator self-inductance of each pahase as a link model to connect the motor to external sources and drives. Unlike the d-q model, the phase model does not therefore require any additional components for connection purposes. The application of the phase model is demonstrated by and example representing a traction drive ciruit. Identical simulation results to those obtained from a different study based on a d-q model are derived.
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  • 69
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 61-71 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: An analogy is described between the TLM algorithm and discrete state-space control theory. The analogy is used to derive the characteristic equations corresponding to parametrized model structures. Characteristic equations corresponding to several widely used node structures are derived by this means and found to be consistent with the observed behaviour of corresponding TLM models. An example is given of the use of the analogy in teh predictive mode.
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  • 70
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 95-107 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: In this work, we show the implementation of two explicit three-dimensional finite-difference beam propagation methods (BPM) on two different parallel computers, namely a transputer array and a Connection Machine (CM). To assess the performance of using parallel computers, serial computer codes of the two methods have ben implemented and a comparison between the speed of the serial and paralledl codes has been made. Large gains in the speed of the paralled FD-BPMs has been obtained compared to the serial implementations. In addition, a comparison between the performance of the transputer array and the CM in executing the two FD-BPMs has been discussed. Finally, to assess and compare the two methods, three different rib waveguides and three different directional couplers have been analysed and the results compared with published results.
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  • 71
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 139-147 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper presents a circuit-based model of a current carrying conductor that can provide instantaneous ohmic losses under surge conditions. The model is frequency independent and can be used to calculate transient current characteristics of surges on overhead transmission lines. The theoretical current distribution under lightning surge conditions is used to demonstrate the validity of the model and the results are compared with values obtained using a finite element analysis package. There is a good correlation between the two methods with the circuit-based model having the advantages of being less cumbersome, requiring shorter computation time and being simple to implement in transient analysis packages.
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  • 72
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    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 8 (1995), S. 331-340 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: This paper presents a new method in TLM for very efficient computation of highly conducting thin shielding walls. Firstly, the impulse response of a finite conducting sheet is computed analytically via inverse Laplace transform. Subsequently, a recursive convolution integral is formulated with the analytical impulse response. This allows a very efficient and accurate calculation of the diffusion process through imperfectly conducting walls.
    Additional Material: 9 Ill.
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  • 73
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    Numerical Linear Algebra with Applications 2 (1995), S. 415-429 
    ISSN: 1070-5325
    Keywords: indefinite ; inverse ; preconditioning ; symmetric ; Toeplitz ; Trench algorithm ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: A modification is presented of the classical O(n2) algorithm of Trench for the direct solution of Toeplitz systems of equations. The Trench algorithm is stable for symmetric matrices that are positive definite, but can be unstable for the indefinite case (and for general matrices). Our modification permits extension of the algorithm to compute approximate inverses of indefinite symmetric Toeplitz matrices, for which the unmodified algorithm breaks down when principal submatrices are singular. As a preconditioner, the approximate inverse has an advantage that only matrix - vector multiplications are required for the solution of a linear system, without forward and backward solves. The approximate inverse so obtained can be sufficiently accurate, moreover, that, when it is used as a preconditioner for the applications investigated, subsequent iteration may not even be necessary. Numerical results are given for several test matrices. The perturbation to the original matrix that defines the modification is related to a perturbation in a quantity generated in the Trench algorithm; the associated stability of the Trench algorithm is discussed.
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  • 74
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    Numerical Linear Algebra with Applications 2 (1995), S. 483-485 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
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  • 75
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    Numerical Linear Algebra with Applications 2 (1995), S. 447-465 
    ISSN: 1070-5325
    Keywords: preconditioned iterative methods ; SSOR factorization ; parallelization ; connection machine ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: A class of parallelizable preconditioned iterative methods for the solution of certain finite difference or finite element linear systems of equations is presented. The methods are based on calculation of approximate inverses of the SSOR factorization. The speed of the methods may be increased by making the approximation of the inverse more accurate. The construction of the preconditioning as well as the solution of the preconditioning systems (realized by matrix-vector multiplication) can be made in parallel over the total amount of meshpoints. The methods are suitable for implementation on massively parallel computers such as connection machines. Problems with constant as well as strongly varying orthotropy are examined and the methods are compared to other parallel techniques with respect to rate of convergence, computational complexity and consumed CM200 computing time. We report a small but significant decrease in computing time compared to the (until now) most frequently used completely parallel preconditioning, the Jacobi method.
    Additional Material: 7 Ill.
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  • 76
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    Numerical Linear Algebra with Applications 2 (1995), S. 533-541 
    ISSN: 1070-5325
    Keywords: plane rotation ; shear product ; Saxpy operation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: An algorithm for pre- or post-multiplication of a matrix by a plane rotation, using only three vector saxpy operations instead of the four vector operations usually considered necessary, is described. No auxiliary storage for overwriting is required. The method is shown to be numerically stable.
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  • 77
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    Numerical Linear Algebra with Applications 2 (1995), S. 487-505 
    ISSN: 1070-5325
    Keywords: biharmonic equation ; rectangular finite elements ; preconditioning ; multilevel methods ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Recently, some new multilevel preconditioners for solving elliptic finite element discretizations by iterative methods have been proposed. They are based on appropriate splittings of the finite element spaces under consideration, and may be analyzed within the framework of additive Schwarz schemes. In this paper we discuss some multilevel methods for discretizations of the fourth-order biharmonic problem by rectangular elements and derive optimal estimates for the condition numbers of the preconditioned linear systems. For the Bogner-Fox-Schmit rectangle, the generalization of the Bramble-Pasciak-Xu method is discussed. As a byproduct, an optimal multilevel preconditioner for nonconforming discretizations by Adini elements is also derived.
    Additional Material: 3 Ill.
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  • 78
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    Numerical Linear Algebra with Applications 2 (1995), S. 87-93 
    ISSN: 1070-5325
    Keywords: QR algorithm ; zero pattern ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: The QR algorithm is a basic algorithm for computing the eigenvalues of dense matrices. For efficiency reasons it is prerequisite that the algorithm is applied only after the original matrix has been reduced to a matrix of a particular shape, most notably Hessenberg and tridiagonal, which is preserved during the iterative process. In certain circumstances a reduction to another matrix shape may be advantageous. In this paper, we identify which zero patterns of symmetric matrices are preserved under the QR algorithm.
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  • 79
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    Numerical Linear Algebra with Applications 2 (1995), S. 95-113 
    ISSN: 1070-5325
    Keywords: arrowhead matrix ; band matrix ; inverse eigenvalue problem ; givens rotations ; singular value decomposition ; updating ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Various plane rotation patterns are presented, which provide stable algorithms for reducing a b-band matrix bordered by p rows and/or columns to (b + p)-band form. These schemes generalize previously presented O(N2) reduction algorithms for matrices of order N, b = 1, and p = 1 to the reduction of more general b-band, p-bordered matrices where b ≥ 1 and p ≥ 1. Moreover, by splitting the matrix into two similarly structured submatrices and chasing nonzeros to the corners in two directions, the newly proposed patterns reduce the number of required rotations and hence the computational cost by one half compared to the other existing one-way chasing algorithms. Symmetric, as well as more general matrices, are considered. An example of the first type is the symmetric arrowhead matrix that arises in solving inverse eigenvalue problems. Examples of the second type are found in updating the singular value decomposition (SVD) and the partial SVD.
    Additional Material: 7 Ill.
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  • 80
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    Numerical Linear Algebra with Applications 2 (1995), S. 243-250 
    ISSN: 1070-5325
    Keywords: Cholesky ; norm inequality ; perturbation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: We show that a certain matrix norm ratio studied by Parlett has a supermum that is O(\documentclass{article}\pagestyle{empty}\begin{document}$\mathop \[\sqrt n \] $\end{document}) when the chosen norm is the Frobenius norm, while it is O(log n) for the 2-norm. This ratio arises in Parlett's analysis of the Cholesky decomposition of an n by n matrix.
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  • 81
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    Numerical Linear Algebra with Applications 2 (1995), S. 271-286 
    ISSN: 1070-5325
    Keywords: linear least squares ; backward perturbations ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Let A be an m × n matrix, b be an m-vector, and x̃ be a purported solution to the problem of minimizing ‖b  -  Ax‖2. We consider the following open problem: find the smallest perturbation E of A such that the vector x̃ exactly minimizes ‖b  -  (A+E)x‖2. This problem is completely solved when E is measured in the Frobenius norm. When using the spectral norm of E, upper and lower bounds are given, and the optimum is found under certain conditions.
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    Numerical Linear Algebra with Applications 2 (1995), S. 287-296 
    ISSN: 1070-5325
    Keywords: block Hessenberg matrix ; block Toeplitz matrix ; linear system ; queue ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: This paper describes a divide-and-conquer strategy for solving block Hessenberg systems. For dense matrices the method is as efficient as Gaussian elimination; however, because it works almost entirely with the original blocks, it is much more efficient for sparse matrices or matrices whose blocks can be generated on the fly. For Toeplitz matrices, the algorithm can be combined with the fast Fourier transform.
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    Numerical Linear Algebra with Applications 2 (1995), S. ii 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
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    Numerical Linear Algebra with Applications 2 (1995), S. 507-531 
    ISSN: 1070-5325
    Keywords: Cholesky decomposition ; singular values ; eigenvalues ; null spaces ; noise spaces ; URV and ULV factorizations ; QR algorithm ; LR algorithm ; Jacobi methods ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: The implicit Cholesky algorithm has been developed by several authors during the last 10 years but under different names. We identify the algorithm with a special version of Rutishauser's LR algorithm. Intermediate quantities in the transformation furnish several attractive approximations to the smallest singular value.The paper extols the advantages of using shifts with the algorithm. The nonorthogonal transformations improve accuracy.
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    Numerical Linear Algebra with Applications 2 (1995), S. 543-545 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
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  • 86
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    Numerical Linear Algebra with Applications 2 (1995), S. 115-133 
    ISSN: 1070-5325
    Keywords: Krylov subspace ; Lanczos process ; symmetric matrix ; conjugate gradients ; minimum residual ; Lehmann intervals ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Approximations to the solution of a large sparse symmetric system of equations are considered. The conjugate gradient and minimum residual approximations are studied without reference to their computation. Several different bases for the associated Krylov subspace are used, including the usual Lanczos basis. The zeros of the iteration polynomial for the minimum residual approximation (harmonic Ritz values) are characterized in several ways and, in addition, attractive convergence properties are established. The connection of these harmonic Ritz values to Lehmann's optimal intervals for eigenvalues of the original matrix appears to be new.
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    Numerical Linear Algebra with Applications 2 (1995), S. 155-171 
    ISSN: 1070-5325
    Keywords: condition number ; norm of a matrix ; matrix completion ; dilation theory ; robust regularization of descriptor systems ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: We study the problem of minimizing the norm, the norm of the inverse and the condition number with respect to the spectral norm, when a submatrix of a matrix can be chosen arbitrarily. For the norm minimization problem we give a different proof than that given by Davis/Kahan/Weinberger. This new approach can then also be used to characterize the completions that minimize the norm of the inverse. For the problem of optimizing the condition number we give a partial result.
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    Numerical Linear Algebra with Applications 2 (1995), S. 191-194 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
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    Numerical Linear Algebra with Applications 2 (1995), S. 173-190 
    ISSN: 1070-5325
    Keywords: block algorithm ; LAPACK ; level 3 BLAS ; iterative refinement ; LU factorization ; backward error analysis ; block diagonal dominance ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Many of the currently popular ‘block algorithms’ are scalar algorithms in which the operations have been grouped and reordered into matrix operations. One genuine block algorithm in practical use is block LU factorization, and this has recently been shown by Demmel and Higham to be unstable in general. It is shown here that block LU factorization is stable if A is block diagonally dominant by columns. Moreover, for a general matrix the level of instability in block LU factorization can be bounded in terms of the condition number K(A) and the growth factor for Gaussian elimination without pivoting. A consequence is that block LU factorization is stable for a matrix A that is symmetric positive definite or point diagonally dominant by rows or columns as long as A is well-conditioned.
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    Numerical Linear Algebra with Applications 2 (1995), S. 135-153 
    ISSN: 1070-5325
    Keywords: orthogonal projection ; numerical rank ; total least squares ; rank revealing QR factorization ; acute perturbation ; subspace angle ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Overdetermined linear systems often arise in applications such as signal processing and modern communication. When the overdetermined system of linear equations AX ≍ B has no solution, compatibility may be restored by an orthogonal projection method. The idea is to determine an orthogonal projection matrix P by some method M such that [à B̃] = P[A B], and ÃX = B̃ is compatible. Denote by XM the minimum norm solution to ÃX = B̃ using method M. In this paper conditions for compatibility of the lower rank approximation and subspace properties of à in relation to the nearest rank-k matrix to A are discussed. We find upper and lower bounds for the difference between the solution XM and the SVD-based total least squares (TLS) solution XSVD and also provide a perturbation result for the ordinary TLS method. These results suggest a new algorithm for computing a total least squares solution based on a rank revealing QR factorization and subspace refinement. Numerical simulations are included to illustrate the conclusions.
    Additional Material: 4 Tab.
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  • 91
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    Numerical Linear Algebra with Applications 2 (1995) 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 92
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    Numerical Linear Algebra with Applications 2 (1995), S. 195-203 
    ISSN: 1070-5325
    Keywords: Jacobi matrix ; arrow matrix ; inverse problem ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: We consider the problem of reconstructing Jacobi matrices and real symmetric arrow matrices from two eigenpairs. Algorithms for solving these inverse problems are presented. We show that there are reasonable conditions under which this reconstruction is always possible. Moreover, it is seen that in certain cases reconstruction can proceed with little or no cancellation. The algorithm is particularly elegant for the tridiagonal matrix associated with a bidiagonal singular value decomposition.
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  • 93
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    Numerical Linear Algebra with Applications 2 (1995), S. 235-241 
    ISSN: 1070-5325
    Keywords: interior-point methods ; trust regions ; conic functions ; conjugate gradients ; linear programming ; nonlinear minimization ; Karmarkar's algorithm ; centering ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: An optimization method is developed based on ellipsoidal trust regions that are defined by conic functions. It provides a powerful unifying theory from which can be derived a variety of interesting and potentially useful optimization algorithms, in particular, conjugate-gradient-like algorithms for nonlinear minimization and Karmarkar-like interior-point algorithms for linear programming.
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  • 94
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    Numerical Linear Algebra with Applications 2 (1995), S. 219-234 
    ISSN: 1070-5325
    Keywords: nonsymmetric matrices ; sparse matrices ; eigenvalue problem ; EISPACK ; LAPACK ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: With the growing demands from disciplinary and interdisciplinary fields of science and engineering for the numerical solution of the nonsymmetric eigenvalue problem, competitive new techniques have been developed for solving the problem. In this paper we examine the state of the art of the algorithmic techniques and the software scene for the problem. Some current developments are also outlined.
    Additional Material: 2 Tab.
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  • 95
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    Numerical Linear Algebra with Applications 2 (1995), S. 251-269 
    ISSN: 1070-5325
    Keywords: eigenvalues ; eigenvectors ; symmetric matrices ; Rayleigh quotient iteration ; convergence ; basins of attraction ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: The Rayleigh quotient iteration method finds an eigenvector and the corresponding eigenvalue of a symmetric matrix. This is a fundamental problem in science and engineering. Parlett and Kahan have shown, in 1968, that for almost any initial vector in the unit sphere, the Rayleigh quotient iteration method converges to some eigenvector. In this paper, the regions of the unit sphere which include all possible initial vectors converging to a specific eigenvector are studied. The generalized eigenvalue problem Ax = λBx is considered. It is shown that the regions do not change when the matrix is shifted or multiplied by a scalar. These regions are completely characterized in the three-dimensional case. It is shown that, in this case, the area of the region of convergence corresponding to the interior eigenvalue is larger than the area of those corresponding to any extreme one. This can be interpreted, with the appropriate choice of probability distribution, as: the probability of converging to an eigenvector corresponding to the interior eigenvalue is larger than the probability of converging to an eigenvector corresponding to any extreme eigenvalue. It is conjectured that the same is true for matrices of any order. Experiments in higher dimensions are presented which conform with the conjecture.
    Additional Material: 7 Ill.
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  • 96
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    Numerical Linear Algebra with Applications 2 (1995), S. 205-217 
    ISSN: 1070-5325
    Keywords: Lanczos method ; spectral Lanczos ; decompostion method ; eigenpairs ; matrix functions ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: Many researchers are now working on computing the product of a matrix function and a vector, using approximations in a Krylov subspace. We review our results on the analysis of one implementation of that approach for symmetric matrices, which we call the spectral lanczos decomposition method (SLDM).We have proved a general convergence estimate, relating SLDM error bounds to those obtained through approximation of the matrix function by a part of its Chebyshev series. Thus, we arrived at effective estimates for matrix functions arising when solving parabolic, hyperbolic and elliptic partial differential equations. We concentrate on the parabolic case, where we obtain estimates that indicate superconvergence of SLDM. For this case a combination of SLDM and splitting methods is also considered and some numerical results are presented.We implement our general estimates to obtain convergence bounds of Lanczos approximations to eigenvalues in the internal part of the spectrum. Unlike Kaniel-Saad estimates, our estimates are independent of the set of eigenvalues between the required one and the nearest spectrum bound.We consider an extension of our general estimate to the case of the simple Lanczos method (without reorthogonalization) in finite computer arithmetic which shows that for a moderate dimension of the Krylov subspace the results, proved for the exact arithmetic, are stable up to roundoff.
    Additional Material: 1 Ill.
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  • 97
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    Numerical Linear Algebra with Applications 2 (1995), S. 311-312 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 98
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    Numerical Linear Algebra with Applications 2 (1995), S. 313-315 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 99
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    Numerical Linear Algebra with Applications 2 (1995), S. 297-310 
    ISSN: 1070-5325
    Keywords: dynamical systems ; eigenvalues ; QR algorithm ; Francis shift ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Notes: For many years techniques from numerical analysis have been applied fruitfully to the study of dynamical systems. In this paper it is shown that the theory of dynamical systems may be applied to certain computational problems. In particular the question of global convergence of various QR algorithms can be reduced to the study of certain vector iterations derived from Schur forms of matrices. The technique is illustrated in determining the convergence behavior of normal Hessenberg matrices under the Francis and multishift QR iterations.
    Additional Material: 3 Ill.
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    New York, NY [u.a.] : Wiley-Blackwell
    Numerical Linear Algebra with Applications 2 (1995) 
    ISSN: 1070-5325
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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