ISSN:
0935-6304
Keywords:
Capillary SFC
;
Solid phase extraction
;
Quantitative analysis
;
Salt-water
;
Surfactants
;
Span surfactants
;
Sorbitan esters
;
Hydrophilic-lipophilic balance (HLB)
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A rapid, simple and quantitative approach to the separation and identification of sorbitan ester surfactants has been developed using capillary supercritical fluid chromatography (SFC). The sorbitan ester surfactants were well separated into five groups: starting materials and mono-, di-, tri-, and tetraesters, with each group consisting of a number of peaks representing different isomers. High purity glycerides of fatty acids were employed to estimate the relative response factors of sorbitan esters, and reliable group-wise integration served for quantitation of the distribution of sorbitan fatty acid esters. A very important parameter, hydrophilic-lipophilic balance (HLB), which describes the hydrophilic and hydrophobic characteristics of surfactants, could be correlated with the distribution of the sorbitan esters. A combination of solid-phase extraction (SPE) and SFC was used to separate, concentrate, and analyze Span-20 from salt-water samples. In comparison with the HPLC method, capillary SFC broadens the scope of the technique to encompass high molecular weight sorbitan polyesters while maintaining high separation efficiency.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240170208
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