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  • Electronic Resource  (15)
  • 2000-2004  (5)
  • 1980-1984  (10)
  • 1
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The surface structure of altered elastic libers and elastotic material in solar elastosis has been described using a scanning electron microscope. There were 3 different areas in the dermis, depending on the degree of changes in elastic fibers: areas of (1) normal-looking fibers, (2) thick, cylindrical fibers, and (3) a large mass of markedly changed fibers. They were mainly located in the deep, middle, and upper dermis, respectively. The normal-looking fibers were the same as the normal elastic fiber. The thick, cylindrical fibers showed various findings ranging from relatively normal to heavily damaged surface. The large mass was composed of a cord-like element and a fine net-like one. There was a transition between the thick, cylindrical fibers and the large mass. It is suggested that the thick, cylindrical fiber is an early event and the mass is more damaged, as one of the elaslolic changes in solar elastosis. It is also suggested thai the thick, cylindrical fiber corresponds to the fibrous form ami the mass to the amorphous form of the elastotic material.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 103 (1981), S. 3652-3653 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Enhanced expression of decay-accelerating factor and CD59/homologous restriction factor 20 in intestinal metaplasia, gastric adenomas and intestinal-type gastric carcinomas but not in diffuse-type carcinomas Aims: Variable expression of the complement regulatory proteins, decay-accelerating factor, CD59/homologous restriction factor 20 (HRF20) and membrane cofactor protein has been shown in human gastrointestinal malignancies, but their expression in gastric cancer has not been fully described. Thus, we immunohistochemically defined the distribution of these proteins in human normal gastric mucosa, intestinal metaplasia, adenomas and gastric cancers. Methods and results: Gastric tissues were obtained by endoscopic biopsy or surgical resection and stained with mouse monoclonal antibodies to decay-accelerating factor, CD59/HRF20, and membrane cofactor protein. In the normal gastric mucosa, membrane cofactor protein was diffusely stained on the basolateral surface of epithelial cells, whereas the expression of decay-accelerating factor and CD59/HRF20 was inconspicuous. In intestinal metaplasia, adenoma and intestinal-type gastric carcinoma cells, decay-accelerating factor and HRF20 were intensely stained on the apical surface; membrane cofactor protein retained its location on the basolateral surface. In diffuse-type gastric carcinomas, the expression of decay-accelerating factor, CD59/HRF20 was lost, but membrane cofactor protein was present on the tumour cell surface. Conclusions: These findings suggest that membrane cofactor protein plays a primary role in the regulation of complement activation in normal and neoplastic gastric cells and that the expression pattern of the complement regulatory proteins is closely related to gastric carcinoma development.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 151 (2004), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Recently, the novel antimicrobial peptide named dermcidin (DCD) was reported in human eccrine sweat glands.Objectives  We investigated the expression of DCD in a variety of cutaneous tumours in order to assess the usefulness of the monoclonal antibody (G-81), which recognizes a fragment of DCD.Patients/methods  We studied the immunoreactivity of the G-81 antibody on 197 cutaneous tumours.Results  A total of 13 of 26 cutaneous mixed tumours showed substantial immunoreactivity. In contrast all the following cases were completely unreactive: (i) epithelial tumours (seborrhoeic keratosis, squamous cell carcinoma, Bowen's disease, actinic keratosis, genital Paget's disease); (ii) follicular tumours (basal cell carcinoma, trichilemmoma, trichoepithelioma, trichoblastoma, keratoacanthoma, proliferating trichilemmal tumour, pilomatricoma); (iii) melanocytic tumours (malignant melanoma, naevus cell naevus, Spitz naevus, blue naevus); (iv) neural tumours (schwannoma, neurofibroma, Merkel cell neoplasm); (v) mesenchymal tumours (soft fibroma, dermatofibroma, dermatofibrosarcoma protuberans, vascular leiomyoma, leiomyosarcoma, lipoma, juvenile xanthogranuloma, angiomyoma); and (vi) other sweat gland tumours (poroid neoplasms, syringoma, cylindroma, clear cell hidradenoma, spiradenoma, syringoid eccrine carcinoma, mucinous carcinoma, apocrine cystadenoma, syringocystadenoma papilliferum, apocrine adenocarcinoma). Twenty-six cutaneous mixed tumours were considered from histopathological findings to be the apocrine type, but 13 of 26 mixed tumours contained some DCD-immunopositive cells that possibly differentiate into eccrine secretory glands.Conclusions  We found the expression of DCD in tubular structures of 50% of cutaneous mixed tumours with apocrine differentiation. These results suggest that a number of cutaneous mixed tumours show both eccrine and apocrine differentiation in the same neoplasm.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 106 (1982), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case of secondary localized cutaneous amyloidosis in solar elastosis was studied by light and electron microscopy. Amyloid deposition was restricted to areas with elastotic changes, and in some areas both changes were intermingled with each other. The amyloid was permanganate-sensitive, and proved to be protein AA. Ultrastructurally it was composed of fine tubular filaments. It is suggested that the amyloid deposition in this case was related to sunlight damage of the skin.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Optical and quantum electronics 16 (1984), S. 9-18 
    ISSN: 1572-817X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract The speckle pattern observed at the output end of a multimode fibre is closely related to the modal noise. In this paper, the average contrast of the speckle pattern is studied as a function of the radial position in the output end plane for three kinds of misalignment of the incident beam, i.e. defocusing, axial misalignment and angular misalignment. It is found that a variation of the speckle contrast is very sensitive to all kinds of misalignment of the incident beam and that its varying form strongly depends on the kind of misalignment of the incident beam. The speckle contrast at the centre of the output end plane is also examined as a function of the magnitude of misalignment. It is found that the contrast increases from a minimum value in the correct alignment to a certain saturated value with an increase of misalignment.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Optical and quantum electronics 16 (1984), S. 197-205 
    ISSN: 1572-817X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract The intensity variation of a speckle pattern on the exit end face of graded-index multimode fibres with a misaligned fibre-to-fibre joint is experimentally studied from its first-order statistics of the average contrast and the probability density function for two different kinds of longitudinal and axial misalignments. It is found that the speckle contrast varies as a function of the radial position with a peak which shifts towards the periphery of the speckle pattern with an increase of the joint loss. A varying form of the speckle contrast also depends on the type of misalignment. The probability density function of the speckle intensity variation is also found to vary as a function of the radial position but to scarcely vary as a function of the joint loss.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 64 (1981), S. 207-211 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Fluorescent microscopy has been used to separate autotrophic from heterotrophic microorganisms in environmental studies. We report on an improvement on this method for measuring standing stock of phytoplankton. Our method employs a membrane filter and can measure numbers of living phytoplankton including fragile flagellates and size of phytoplankton cells. This method was successfully used in Tokyo Bay and Kuroshio regions.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 261-263 (Apr. 2004), p. 1067-1072 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Evaluation method of nano-scale internal cracks by ultrasonic atomic force microscopy (UAFM) is proposed based on two approaches. The first one is a linear vibration analysis of the contact stiffness calculated from a finite element method analysis of a model including a subsurface gap. The second one is a nonlinear vibration analysis of a stiffening or softening spring representing the opening-and-closing behavior of the gap. These methods were verified by obtaining the resonance frequency mapping, the load dependence of the resonance frequency and the resonance spectra in UAFM on a subsurface gap in highly oriented pyrolytic graphite. As a result, it was proved that the proposed method is useful for evaluating the opening-and-closing behavior of the gap. Although the present study is focused on a nano-scale gap, this method is applicable to larger scale cracks using a larger tip and more stiff support than those used in AFM
    Type of Medium: Electronic Resource
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