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  • 1
    Electronic Resource
    Electronic Resource
    Low thermal expansion polymide buried ridge waveguide AlGaAs/GaAs single-quantum-well laser diode (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 63 (1988), S. 964-966 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A novel ridge waveguide laser diode has been developed in which the ridge is buried in a newly developed polyimide with a low thermal expansion coefficient close to that of AlGaAs which reduces the thermal stress to the junction and simplifies the wafer processing. A planar configuration, which is suitable for optoelectronic integration and an episide down mount for high-power operation, has been achieved by an etch-back process. Under cw operation, a low threshold current of 15 mA at 25 °C, a characteristic temperature T0 of 145 K, and maximum power output higher than 30 mW/facet have been obtained in a molecular-beam-epitaxial-grown graded-index separate confinement heterostructure single-quantum-well laser emitting at 780 nm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.340042
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  • 2
    Electronic Resource
    Electronic Resource
    Multilevel construction of seeded-laterally epitaxial silicon films on insulator (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 62 (1987), S. 126-130 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new seed structure, partially thickened silicon films on insulator (PTS), is proposed for multilevel seeded-laterally epitaxial silicon films on insulator (SOI). Two-level seeded-laterally epitaxial silicon films on thick SiO2 (2.5 μm) were successfully fabricated, using the PTS structure in conjunction with the electron-beam technique. The SOI surface flatness after recrystallization was also improved by the PTS. Through computer simulation of the electron-beam recrystallization process, it is determined that the PTS structure enhances the lateral heat conduction within the SOI. This is important in smoothly melting the seed and field SOI regions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.339171
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  • 3
    Electronic Resource
    Electronic Resource
    Highly controllable pseudoline electron-beam recrystallization of silicon on insulator (1986)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 59 (1986), S. 2971-2976 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new electron-beam annealing technique, an amplitude modulated pseudoline electron beam, has been proposed for recrystallization of large-area silicon layers on insulating materials (SOI). The technique utilizes an amplitude modulated sinusoidal wave for high-frequency beam oscillation. Through computer simulation of the temperature distribution for the sample surface, precise control of the position probability density profile of the line beam proved to be essential in realizing wide and uniform annealing. An optimum oscillation waveform was determined from the simulation. A large-area SOI, 4 mm (D'Alembertian), was successfully recrystallized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.336911
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  • 4
    Electronic Resource
    Electronic Resource
    A rapid detection of circulating antigens of Dirofilaria immitis in dogs by a dot enzyme-linked immunosorbent assay (1988)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 47 (1988), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract This report describes a dot enzyme-linked immunosorbent assay (Dot-ELISA) for detecting circulating antigens in the sera of dogs infected with Dirofilaria immitis (D. immitis). Circulating D. immitis antigens could be detected in 24 of 25 infected dogs. The remaining animal had two immature worms. However, non-infected dogs and dogs infected with other parasites were all negative, Few cross-reactions to different parasite antigens were observed. The advantages of the Dot-ELISA include; 1) there is no need for pretreatment and dilution of sera and samples could be immediately bound to nitrocellulose paper set into microfiltration apparatus, 2) this assay could be carried out within 2 h at room temperature, 3) the resulting enzyme-reaction could be measured by both visual observation and densitometric reading.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1988.tb02367.x
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  • 5
    Electronic Resource
    Electronic Resource
    Immunological evidence for two types of PQQ-dependent d-glucose dehydrogenase in bacterial membranes and the location of the enzyme in Escherichia coli (1986)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 37 (1986), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Using an antibody raised against d-glucose dehydrogenase (EC 1.1.99.17) purified from Pseudomonas fluorescens, immuno-cross-reactivity with the enzymes from several bacterial strains and localization of the enzyme in Escherichia coli were examined. The antibody cross-reacted with glucose dehydrogenases from various Gram-negative bacteria examined. As a result, it became apparent that the enzymes from Gluconobacter, Acetobacter, Pseudomonas and Acinetobacter, which existed as holoenzymes in the membranes, had lower molecular weights than those from E. coli and Klebsiella, which were apoenzymes.Treatment with trypsin of right-side out and inside-out membrane vesicles from E. coli clearly demonstrated that d-glucose dehydrogenase was located on the outer surface of the cytoplasmic membrane of E. coli, as had been suggested for Pseudomonas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1986.tb01782.x
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  • 6
    Electronic Resource
    Electronic Resource
    Induction of cartilage and bone by dentin demineralized in citric acid (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 21 (1986), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The capacity of a roll of dentin demineralized by either 0.6N HCl, pH 1 for 3 minutes or 3 hours, or by 3M (9N) citric acid, pH 1, for 3 minutes, to induce cartilage and bone when implanted in muscle, was investigated. Serial sections of specimens were examined 7, 10, 14. 17, and 21 days after implantation, and randomly selected sections analyzed histomorphometrically. Cartilage was induced on the internal aspect of the citric acid-demineralized dentin roll, but significantly less than that induced after demineralization with HCl. The quantity of bone deposited subsequently did not significantly exceed the amount of cartilage that preceded it in relation to any of the preparations used. The results suggest that citric acid-demineralized dentin induces chondrogenesis and osteogenesis when implanted in muscle, but does so less effectively than does HCl-demineralized dentin, and only within the confines of a microenvironment. It is therefore unlikely that citric acid demineralization of root surface results in induction of cementum by this mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1986.tb01456.x
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  • 7
    Electronic Resource
    Electronic Resource
    Kimura's disease and its relation to angiolymphoid hyperplasia with eosinophilia: report of three cases and review of the literature (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 15 (1986), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Kimura's disease, eosinophilic granuloma of soft tissues, is a chronic inflammatory condition and appears as subcutaneous tumor-like nodules in the head and neck regions. Histopathologically, it is characterized by the presence of lymphoid follicles, marked infiltration of eosinophils, fibrosis and vascular proliferation. This disease occurring in the orofacial region is relatively rare, only 14 cases having been previously reported. We describe 3 additional cases of Kimura's disease and discuss these in relation to angiolymphoid hyperplasia with eosinophilia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1986.tb00593.x
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of low level radiation upon the hematopoietic stem cell: Implications for leukemogenesis (1987)
    Springer
    Radiation and environmental biophysics 26 (1987), S. 103-114 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary These studies have addressed firstly the effect of single small doses of x-rays upon murine hematopoietic stem cells to obtain a better estimate of theD q . It is small, of the order of 20 rad. Secondly, a dose fractionation schedule that does not kill or perturb the kinetics of hemopoietic cell proliferation was sought in order to investigate the leukemogenic potential of low level radiation upon an unperturbed hemopoietic system. Doses used by others in past radiation leukemogenesis studies clearly perturb hemopoiesis and kill a detectable fraction of stem cells. The studies reported herein show that 1.25 rad every day decrease the CFU-S content of bone marrow by the time 80 rads are accumulated. Higher daily doses as used in published studies on radiation leukemogenesis produce greater effects. Studies on the effect of 0.5, 1.0, 2.0, and 3.0 rad 3 times per week are under way. Two rad 3 times per week produced a modest decrease in CFU-S content of bone marrow after an accumulation of 68 rad. With 3.0 rad 3 times per week an accumulation of 102 rad produced a significant decrease in CFU-S content of bone marrow. Dose fractionation at 0.5 and 1.0 rad 3 times per week has not produced a CFU-S depression after accumulation of 17 and 34 rad. Radiation leukemogenesis studies published to date have utilized single doses and chronic exposure schedules that probably have significantly perturbed the kinetics of hematopoietic stem cells. Whether radiation will produce leukemia in animal models with dose schedules that do not perturb kinetics of hematopoietic stem cells remains to be seen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01211405
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  • 9
    Electronic Resource
    Electronic Resource
    Cytotoxic effects of a leukocidin from Fusobacterium necrophorum on bovine hepatic cells (1987)
    Springer
    Medical microbiology and immunology 177 (1987), S. 27-32 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leukocidin in F. necrophorum infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190308
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  • 10
    Electronic Resource
    Electronic Resource
    Proliferative activity of meningiomas as evaluated by bromodeoxyuridine uptake examination (1986)
    Springer
    Acta neurochirurgica 81 (1986), S. 135-141 
    Details
    ISSN: 0942-0940
    Keywords: Bromodeoxyuridine uptake examination ; meningioma ; proliferative activity ; recurrence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Proliferative activity of meningiomas was examined in 12 consecutive cases by administering bromodeoxyuridine (BrdU) before surgical removal and by immunohistochemical staining of the removed tumours using anti-BrdU monoclonal antibody (anti-BrdU MAb) to detect BrdU-labelled tumour cells. The 12 cases consisted of 6 with a primary tumour and 6 with a recurrent tumour. All of the tumours contained labelled cells and the labelling index (LI) was obtained in each tumour. The highest average LI was 13.6% and the second highest was 9.0% both in recurrent cases of histologically malignant meningothelial meningioma. The high LIs of both cases were thought to correspond well with the rapid recurrence of the tumour. The average LI of a case of recurrent haemangiopericytic tumour was 2.0%, and that of a case of meningioma associated with von Recklinghausen disease was 1.5%. The other 8 meningiomas showed the average LIs ranging from 0.1 to 0.9%, which were considered to be the LIs of usual benign meningiomas. The results of the BrdU uptake examination was considered to reflect well the clinical behaviour of meningiomas. The usefulness of the BrdU uptake examination in brain tumours, which can be employed in the clinical practice without any serious side-effects, is stressed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401236
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