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  • 1995-1999  (5)
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  • 1996  (5)
  • 1991  (6)
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  • 1995-1999  (5)
  • 1990-1994  (6)
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  • 1
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Wall conditioning in the Tokamak Fusion Test Reactor (TFTR) [K. M. McGuire et al., Phys. Plasmas 2, 2176 (1995)] by injection of lithium pellets into the plasma has resulted in large improvements in deuterium–tritium fusion power production (up to 10.7 MW), the Lawson triple product (up to 1021 m−3 s keV), and energy confinement time (up to 330 ms). The maximum plasma current for access to high-performance supershots has been increased from 1.9 to 2.7 MA, leading to stable operation at plasma stored energy values greater than 5 MJ. The amount of lithium on the limiter and the effectiveness of its action are maximized through (1) distributing the Li over the limiter surface by injection of four Li pellets into Ohmic plasmas of increasing major and minor radius, and (2) injection of four Li pellets into the Ohmic phase of supershot discharges before neutral-beam heating is begun. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 62 (1991), S. 982-985 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Small alignment errors of right-angle linkage monochromators typical to many x-ray absorption fine structure beamlines can cause significant errors in the energy calibrations. A 1° misalignment produces errors greater than 1 keV over the hard x-ray operating range of a typical monochromator. The energy error caused by such misalignments is analyzed and its mathematical form given. The error can be corrected by inverting the expression and the amount of misalignment determined by accurate energy measurements at a few points. The accuracy of the corrections is tested. The effects of this error on x-ray absorption fine structure data and their interpretation are also discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effect of isotope on confinement in high-recycling, L-mode plasmas is studied on the Tokamak Fusion Test Reactor (TFTR) [see D. M. Meade, J. Fusion Energy 7, 107 (1988)] by comparing hydrogen and deuterium plasmas with the same magnetic field and similar electron densities and heating power, with both Ohmic and deuterium-neutral-beam heating. Following a long operational period in deuterium, nominally hydrogen plasmas were created through hydrogen glow discharge and hydrogen gas puffing in Ohmic plasmas, which saturated the exposed limiter surface with hydrogen and raised the H/(H+D) ratio from 10±3% to 65±5%. Ohmic deuterium discharges obtained higher stored energy and lower loop voltage than hydrogen discharges with similar limiter conditions. Neutral-beam power scans were conducted in L-mode plasmas at minor radii of 50 and 80 cm, with plasma currents of 0.7 and 1.4 MA. To minimize transport differences from the beam deposition profile and beam heating, deuterium neutral beams were used to heat the plasmas of both isotopes. Total stored energy increased approximately 20% from nominally hydrogen plasmas to deuterium plasmas during auxiliary heating. Of this increase about half can be attributed to purely classical differences in the energy content of unthermalized beam ions. Kinetic measurements indicate a consistent but small increase in central electron temperature and total stored electron energy in deuterium relative to hydrogen plasmas, but no change in total ion stored energy. No significant differences in particle transport, momentum transport, and sawtooth behavior are observed. Overall, only a small improvement (∼10%) in global energy confinement time of the thermal plasma is seen between operation in hydrogen and deuterium. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Recent operation of the Tokamak Fusion Test Reactor (TFTR) [Plasma Phys. Controlled Nucl. Fusion Research 1, 51 (1986)] has produced plasma equilibria with values of Λ≡βp eq+li/2 as large as 7, εβp dia≡2μ0ε〈p⊥〉/〈〈Bp〉〉2 as large as 1.6, and Troyon normalized diamagnetic beta [Plasma Phys. Controlled Fusion 26, 209 (1984); Phys. Lett. 110A, 29 (1985)], βNdia≡108〈βt⊥〉aB0/Ip as large as 4.7. When εβp dia(approximately-greater-than)1.25, a separatrix entered the vacuum chamber, producing a naturally diverted discharge that was sustained for many energy confinement times, τE. The largest values of εβp and plasma stored energy were obtained when the plasma current was ramped down prior to neutral beam injection. The measured peak ion and electron temperatures were as large as 24 and 8.5 keV, respectively. Plasma stored energy in excess of 2.5 MJ and τE greater than 130 msec were obtained. Confinement times of greater than 3 times that expected from L-mode predictions have been achieved. The fusion power gain QDD reached a value of 1.3×10−3 in a discharge with Ip=1 MA and εβp dia=0.85. A large, sustained negative loop voltage during the steady-state portion of the discharge indicates that a substantial noninductive component of Ip exists in these plasmas. Transport code analysis indicates that the bootstrap current constitutes up to 65% of Ip. Magnetohydrodynamic (MHD) ballooning stability analysis shows that, while these plasmas are near, or at the βp limit, the pressure gradient in the plasma core is in the first region of stability to high-n modes.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In the Tokamak Fusion Test Reactor (TFTR) [Plasma Phys. Controlled Fusion 26, 11 (1984)], the highest neutron source strength Sn and D–D fusion power gain QDD are realized in the neutral-beam-fueled and heated "supershot'' regime that occurs after extensive wall conditioning to minimize recycling. For the best supershots, Sn increases approximately as P1.8b. The highest-Q shots are characterized by high Te (up to 12 keV), Ti (up to 34 keV), and stored energy (up to 4.7 MJ), highly peaked density profiles, broad Te profiles, and lower Zeff. Replacement of critical areas of the graphite limiter tiles with carbon-fiber composite tiles and improved alignment with the plasma have mitigated the "carbon bloom.'' Wall conditioning by lithium pellet injection prior to the beam pulse reduces carbon influx and particle recycling. Empirically, QDD increases with decreasing pre-injection carbon radiation, and increases strongly with density peakedness [ne(0)/〈ne〉] during the beam pulse. To date, the best fusion results are Sn=5×1016 n/sec, QDD=1.85×10−3, and neutron yield=4.0×1016 n/pulse, obtained at Ip=1.6–1.9 MA and beam energy Eb=95–103 keV, with nearly balanced co- and counter-injected beam power. Computer simulations of supershot plasmas show that typically 50%–60% of Sn arises from beam–target reactions, with the remainder divided between beam–beam and thermonuclear reactions, the thermonuclear fraction increasing with Pb. The simulations predict that QDT=0.3–0.4 would be obtained for the best present plasma conditions, if half the deuterium neutral beams were to be replaced by tritium beams. Somewhat higher values are calculated if D beams are injected into a predominantly tritium target plasma. The projected central beta of fusion alphas is 0.4%–0.6%, a level sufficient for the study of alpha-induced collective effects.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Steady-state and perturbative transport analysis are complementary techniques for the study of transport in tokamaks. These techniques are applied to the investigation of auxiliary-heated L-mode and supershot plasmas in the tokamak fusion test reactor (TFTR) [R. J. Hawryluk et al., Plasma Physics and Controlled Nuclear Fusion Research, Proceedings of the 11th International Conference, Kyoto, 1986 (IAEA, Vienna, 1987), Vol. 1, p. 51.]. In the L mode, both steady-state and perturbative transport measurements reveal a strong temperature dependence that is consistent with electrostatic microinstability theory and the degradation of confinement with neutral beam power. Steady-state analysis of the ion heat and momentum balance in supershots indicates a reduction and a significant weakening of the power-law dependence on the transport in the center of the discharge.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A variety of experiments have been performed on the TFTR tokamak [Wilson et al., Plasma Physics and Controlled Nuclear Fusion Research 1988 (IAEA, Vienna, 1989), Vol. 1, p. 691] utilizing ion cyclotron range of frequencies (ICRF) heating. Of special interest has been the insight into plasma performance gained by utilizing a different heating scheme other than the usual neutral beam injection (NBI). Utilizing ICRF heating allows control over the power deposition profile independent of the plasma fueling profile. In addition, by varying the minority concentration the power split between ion and electron heating can be varied. Confinement has been examined in high recycling gas fueled discharges, low recycling supershot plasmas, and peaked density pellet fueled discharges. Global confinement is found not to be affected by the method or localization of plasma heating, but the calculated local diffusivities vary with the power deposition profile to yield similar global values. In addition, sawtooth stabilization observed with ICRF heating has been investigated and found to occur in qualitative agreement with theory. ICRF sawtooth stabilized discharges exhibit peaked temperature and density profiles and have a safety factor q that appears to fall well below unity on axis.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Single injections of recombinant cytokines/chemokines into tissue have provided insights into their possible roles during the inflammatory response. Adenoviral technology may allow us to mimic the in vivo situation more closely, with protein generated in a continuous but transient fashion. Replication-deficient human type 5 adenovirus containing a rat macrophage inflammatory protein-2 (MIP-2) gene insertion and cytomegalovirus promoter was injected into the mouse brain to investigate the inflammatory response to continuous overproduction of MIP-2. Adenovirus with a LacZ gene insertion expressing β-galactosidase was used as a control. At doses of 104 to 107 plaque-forming units, a minimal inflammatory response was detected to the LacZ virus, with leukocyte recruitment that was restricted to the injection site. A dose of 107 plaque-forming units of both the LacZ and the MIP-2 vector produced extensive transgene product expression that persisted for at least 7 days. Astrocytes, recognized by their morphology, were the predominant cell type expressing MIP-2 and β-galactosidase. A dose of 107 plaque-forming units of MIP-2 vector caused dramatic polymorphonuclear leukocyte (PMN) recruitment to the brain parenchyma after 2 days. PMN recruitment was still observed after 4 and 7 days, but had become more localized to the injection site and was associated with numerous foam-like macrophages. At both 2 and 7 days the blood-brain barrier was breached in the region of leukocyte recruitment. Despite the extent of leukocyte recruitment there were no overt signs of neuronal degeneration or demyelination. Our findings demonstrate that continuous production of MIP-2 in the CNS results in persistent PMN recruitment to the brain parenchyma with no evidence of tachyphylaxis. The lack of PMN recruitment to the brain parenchyma following CNS injury may be a result of deficient production of PMN chemoattractants.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 49 (1996), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Larval sea bass Dicentrarchus labrax of 27 days old were reared on Artemia enriched with Super Selco©, Tuna Orbital Oil or Yeast. The first diet is commonly used in mariculture for larval rearing, the second diet was designed to deliver an optimal docosahexaenoic acid (22: 6n-3) to eicosapentaenoic acid (20: 5n-3) ratio, and the third diet was deficient in docosahexaenoic acid (22: 6n-3). The eyes of these larvae were analysed after 28 days and the molecular species of the three main phospholipid classes, phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylserine (PS) determined. Eyes from larvae fed Artemia enriched with yeast showed large decreases in molecular species containing 22: 6n-3 compared to those supplemented with tuna orbital oil, most notably in 16: 0/22: 6n-3 PC which fell from 10.6 to 0.4%, in 22: 6n-3/22: 6n-3 and 18: 1/22: 6n-3 PE which fell from 29.6 to 0.3% and from 10.8 to 1.1% respectively, and in 22: 6n-3/22: 6n-3 PS which fell from 34.3 to 1.7%. Molecular species containing all other fatty acids, and especially 20: 5n-3, were elevated in eyes from the yeast-supplemented fish. In larvae fed Artemia enriched with Super Selco, amounts of eye 22: 6n-3/22: 6n-3 phospholipid were slightly lower in all three phospholipid classes compared to eyes from the tuna orbital oil-supplemented larvae. There was also a trend of decreased saturated fatty acid/22: 6n-3 and monounsaturated fatty acid/22: 6n-3 molecular species in all classes from the Super Selco-supplemented fish, the deficits being made up with molecular species containing 20: 5n-3 and 22: 5n-3. These results are discussed in relation to larval viability with particular respect to visual function.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1437-160X
    Keywords: Keratan sulphate ; Proteoglycans ; Osteoarthritis ; Chronic pyrophosphate arthropathy ; Acute pyrophosphate arthropathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to evaluate the effect of calcium pyrophosphate dihydrate (CPPD) deposition on articular cartilage catabolism, the proteoglycans released into normal synovial fluid were compared with those in synovial fluid obtained from patients with osteoarthritis (OA), chronic pyrophosphate arthropathy (CPA) and acute pyrophosphate arthropathy (APA). Keratan sulphate (KS) was measured by the modified 1,9-dimethylmethylene blue (DMB) assay in synovial fluids treated with chondroitin ABC lyase. This enzyme was found to eliminate all of the sulphated glycosaminoglycans in synovial fluid except KS. In OA, CPA and APA the concentrations of KS were found to be significantly higher than in normal synovial fluid (NSF) (P〈0.01). Similar KS concentrations were observed in CPA and APA. In CPA they were significantly higher than in OA (P〈0.02). The size distribution of proteoglycan fragments varied between different patients with the same disease, but only minor differences were observed in patients with OA and CPA who were matched for age, sex and disease severity. Furthermore, the size distribution of proteoglycan fragments in the acute and chronic phases of pyrophosphate arthritis was similar. Thus although in pyrophosphate arthritis the rate at which proteoglycans are released from the cartilage may be greater than in OA or normal joints, the fundamental processes governing the release of these macromolecules may be the same.
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