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  • 2005-2009  (1)
  • 1985-1989  (13)
  • 1980-1984  (6)
  • 1
    Electronic Resource
    Electronic Resource
    AGE-RELATED CHANGES IN BLOOD PRESSURE, HEART RATE AND BAROREFLEX SENSITIVITY IN SHR (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 16 (1989), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 〈list xml:id="l1" style="custom"〉1The age-related changes in mean arterial pressure (MAP), heart rate (HR), and baroreflex sensitivity (BRS) were studied in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats from 4 to 20 weeks of age.2Intra-arterial blood pressure (BP) was continuously recorded for 24 h in conscious, freely moving rats. Twenty-four hour MAP and HR were calculated by an online computer. Baroreflex sensitivity was measured by phenylephrine infusion.3In SHR, BRS was significantly lower than in WKY as early as 4-5 weeks, at which time MAP in SHR was only slightly raised. During subsequent weeks, rapid increase in MAP occurred in SHR, in association with progressive bradycardia.4It was concluded that a reduced BRS may be detected in young prehypertensive SHR and this impairment of BRS may be central in origin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1989.tb02999.x
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of famotidine, mosapride and tandospirone for treatment of functional dyspepsia (2005)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 21 (2005), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : An effective therapeutic strategy for functional dyspepsia (FD) has not been well-established.Aim : We investigated and compared the therapeutic effects of famotidine, mosapride and tandospirone for the control of dyspeptic symptoms.Methods : Fully examined FD patients of outpatient clinics at seven different medical centres were enrolled in the study. They were randomly assigned to three groups based on the type of drug administered: famotidine, mosapride and tandospirone. The effects of treatment over 4 weeks were assessed by visual analogue scales.Results : All of the drugs showed beneficial effects, although famotidine was the most effective for symptom relief, which was significantly greater than tandospirone, while the effect of mosapride was similar to that of famotidine. No subtype of FD showed a better response to a particular type of drug.Conclusions : For the treatment of FD, famotidine demonstrated the best therapeutic effect, followed by mosapride, while that of tandospirone was significantly lower.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2005.02472.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    First Results from AMY (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 535 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb51548.x
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  • 4
    Electronic Resource
    Electronic Resource
    Complex analytic curves and maximal surfaces (1989)
    Springer
    Monatshefte für Mathematik 108 (1989), S. 255-276 
    Details
    ISSN: 1436-5081
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Maximal immersions of a surfaceM 2 inton-dimensional Lorentz space which are isometric to a fixed holomorphic mapping ofM 2 into complex Lorentz space are determined. The main tool is an adaption of Calabi's Rigidity Theorem. Such an adaption is necessary because of the existence of degenerate hyperplanes in complex Lorentz space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01501129
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  • 5
    Electronic Resource
    Electronic Resource
    Genetic polymorphism of human factor I (C3b inactivator) (1985)
    Springer
    Human genetics 〈Berlin〉 71 (1985), S. 45-48 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Genetic polymorphism of human factor I (C3b inactivator) has been described using polyacrylamide gel isoelectric focusing electrophoresis of neuraminidase-treated EDTA plasma samples followed by electrophoretic blotting technique. In 435 individuals three different common patterns were observed, and these were controlled by two common alleles at a single locus. The results of typing family material confirmed autosomal codominant Mendelian inheritance. Two common alleles were designated FI*B and FI*A, and gene frequencies were estimated to be 0.8931 and 0.1069 for FI*B and FI*A, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium. Linkage studies failed to show close linkage between factor I and the major histocompatibility complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00295667
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  • 6
    Electronic Resource
    Electronic Resource
    Genetic polymorphism of the seventh component of complement in a Japanese population (1984)
    Springer
    Human genetics 〈Berlin〉 66 (1984), S. 279-281 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Genetic polymorphism of C7 in a Japanese population has been described, using polyacrylamide gel isoelectric focusing electrophoresis followed by an electrophoretic blotting technique. Phenotypes of C7 were classified into six common patterns, and observed phenotypes were produced by autosomal codominant at a single locus with three alleles. Three common alleles, designated C7*B, C7*M and C7*A, were found, and gene frequencies calculated from 494 individuals showed C7*B=0.858, C7*M=0.096 and C7*A=0.046, respectively. It is noteworthy that both C7*M and C7*A have polymorphic frequencies in the Japanese population. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium. Results indicate that the electrophoretic blotting technique, which has high specificity and sensitivity, is applicable in the study of heterogeneity of protein antigens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00286617
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  • 7
    Electronic Resource
    Electronic Resource
    A new BF F variant by polyacrylamide gel isoelectric focusing (1987)
    Springer
    Human genetics 〈Berlin〉 77 (1987), S. 295-296 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Polyacrylamide gel isoelectric focusing followed by electroblotting with enzyme immunoassay was done for the investigation of allotypes of properdin factor B (BF) in serum from 326 Japanese subjects. A new BF F variant tentatively designated BF*Fb1 (b=basic) was detected, the isoelectric point of each band of homozygous BF Fb1 being higher than of BF FF. Family data were in accordance with transmission by mendelian inheritance. The allele frequencies calculated from 326 Japanese subjects were 0.7945, 0.1825, 0.0215, and 0.0015 for BF*S, BF*F, BF*Fb1, and BF*F075, respectively, with that of variant BF*Fb1 being a polymorphic frequency. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00284492
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  • 8
    Electronic Resource
    Electronic Resource
    MR imaging of syringobulbia with giant syrinx (1988)
    Springer
    Neuroradiology 30 (1988), S. 442-443 
    Details
    ISSN: 1432-1920
    Keywords: Syringobulbia ; MR image ; Meningioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Syringobulbia with a large syrinx was revealed by MR imaging. The syrinx extended from the medulla to vertebral level T10. We suspect that this giant syrinx may be produced by a congenital meningioma at C7, generating pulsatile flow in the original syrinx and causing a giant syrinx.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00404111
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  • 9
    Electronic Resource
    Electronic Resource
    Garcin syndrome with hypopituitarythm (1988)
    Springer
    Neuroradiology 30 (1988), S. 447-448 
    Details
    ISSN: 1432-1920
    Keywords: Garcin syndrome ; MR imaging ; Nasopharyngeal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report a Garcin syndrome due to nasopharyngeal carcinoma invading the skull base. MR Imaging of this patient shows the position of the tumour and reveals how the tumor invaded the skull and the effect of treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00404113
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  • 10
    Electronic Resource
    Electronic Resource
    Phenytoin elimination kinetics in two children with drug intoxication (1980)
    Springer
    European journal of pediatrics 135 (1980), S. 69-71 
    Details
    ISSN: 1432-1076
    Keywords: Phenytoin toxicity ; Michaelis-Menten kinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two girls aged 6 and 10 years treated with anticonvulsants developed nystagmus and ataxia. The peak plasma concentrations of phenytoin were 42.6 and 46.6 μg/ml, respectively, compatible with phenytoin toxicity. The decline in plasma phenytoin levels did not fit first order kinetics, but followed Michaelis-Menten kinetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00445896
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