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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 85 (1976), S. 279-287 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einer interklinischen Studie werden 126 Fälle von kindlichen Osteosarkomen analysiert. Es findet sich eine zunehmende Häufigkeit bis zum 15. Lebensjahr bei geringem Überwiegen des männlichen Geschlechtes. Das kindliche Osteosarkom bevorzugt den distalen Femur, die proximale Tibia und den proximalen Humerus. Die Behandlung wurde — bedingt durch die verschiedenen Kooperationszentren — uneinheitlich durchgeführt. Überlebende finden sich in allen Altersgruppen. Multiple Metastasen — meist in den Lungen, aber auch im Skelet — treten gehäuft innerhalb des 1. Jahres und fast immer innerhalb der ersten 2 1/2 Jahre nach Diagnosestellung auf. Zur Prognosebeurteilung genügt daher die 21/2-Jahres-Grenze. Die anscheinend besseren Ergebnisse nach frühzeitiger Amputation lassen diese Methode beim kindlichen Osteosarkom empfehlenswert erscheinen. Mit der alleinigen Strahlentherapie konnten keine Heilungen erzielt werden. Zusätzlich zur frühzeitigen Radikalbehandlung läßt die intensive prophylaktische Chemotherapie bessere Resultate erwarten.
    Notes: Summary 126 osteosarcoma under the age of 15 years are followed up in an interclinical study. There is a steady increase of tumor incidence towards the 15th year with a slight male preponderance. The main sites of the tumor are the distal femur followed by the proximal tibia and humerus. Evidence of multiple metastases is most often present in the lungs, less often in the skeleton. Nearly always metastases became evident within 2 1/2 years after diagnosis (98%). Therefore the 2 1/2-year disease—free survival rate seems to be sufficient for prognostic evaluation. The over all 2 1/2-year survival rate was 17,5%. Though the different methods of treatment are not statistically valid, the best results can be expected after early amputation. By radiotherapy alone no cure has been achieved. Survivals were seen at any age and at any site of long bones (distal femur, proximal tibia, humerus, femur, distal radius). Prognosis of osteosarcoma in the childhood is similar to that of the adult group.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 339 (1975), S. 679-679 
    ISSN: 1435-2451
    Keywords: Metastasis, verebral ; Paraplegia ; Stabilization, surgical ; Wirbelsäulenmetastasen ; Querschnittsgefahr ; Wirbelverblockung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Als Alternative zu der nur unbefriedigenden dorsalen Laminektomie bei Wirbelkörpermetastasen und drohendem Querschnitt bietet sich die Wirbelkörperausräumung vom ventrolateralen Zugang mit Verblockung durch Knochenzement und Seitenplatte an. Indikation: drohender Querschnitt, therapieresistenze Schmerzen, Wirbelsäuleninstabilität. Material und Resultate: bei allen 27 Fällen bestand sofort Schmerzfreiheit, die durchschnittliche Zeit der Gehfähigkeit bei den 21 komplikationslosen Fällen: 11,4 Monate. Beste Ergebnisse bei Thyreoidea-Mammacarcinomen und Myelomen.
    Notes: Summary Dorsal laminectomy has unsatisfactory results in many cases of metastases to vertebral bodies and threatened paraplegia. The method with ventrolateral approach, partial dissection of the vertebral body, and stabilization by means of bone cement on a plate presents an alternative form of treatment. Indications are threatened paraplegia, pain, and instability of the vertebral column. In a series of 27 patients, freedom from pain was experienced immediately in all cases; in the 21 cases with no complications the average period of walking ability was 11.4 months. The best results were obtained in patients with carcinoma of the thyroid or the breast and in those with myeloma.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Social development 8 (1999), S. 0 
    ISSN: 1467-9507
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: Although a multitude of factors may be involved in the development of children’s violent behavior, the actual aggressive act is preceded by a decision-making process that serves as the proximal control mechanism. The primary goal of this longitudinal study was to understand the nature of this proximal control mechanism involved in children’s aggressive acts by focusing on two aspects of social cognitions: social information processing and stored knowledge (i.e., internal knowledge structures that are the latent memories of past events). It was hypothesized that: (1) children with hostile knowledge structures will display more biased patterns of aggressive social information processing than children whose knowledge structures are less hostile and negative; (2) children who display hostile knowledge structures will behave in chronically aggressive ways; and (3) the development of hostile knowledge structures and hostile patterns of social information processing contribute to the stability of aggressive behavior and thus partially mediate the relation between early and later aggressive behavior. 585 boys and girls (19% African-American) were followed from kindergarten through eighth grade. Results from this investigation support the hypotheses and are discussed in terms of the significance of the inclusion of knowledge structures in our theories of the mental processes involved in children’s violent behaviour.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 53 (1998), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 759 (1995), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: The all-sky survey of Sc galaxies with estimated redshift–independent distances presented by Haynes et al. (1993) is used to map the peculiar velocity field in the local universe. After suitable correction for Malmquist and selection biases, the resulting peculiar velocities are used to estimate the mass density in the local universe using the POTENT method (Dekel 1994). The resulting density field is compared with the distribution of galaxies.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1520-6041
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 100 (1978), S. 4119-4124 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 34 (1995), S. 6231-6232 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Physiologia plantarum 102 (1998), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In ectomycorrhizae auxins are proposed to attenuate elicitor-induced defence reactions in the host plant. To examine this hypothesis we compared the elicitor-induced accumulation of peroxidase isoforms between suspension-cultured spruce (Picea abies[L.] Karst.) cells incubated in media with and without auxins. In spruce cells changes in ionically and covalently wall-bound as well as symplasmic peroxidase (EC 1.11.1.7) activities were observed when elicitors from the following fungal species were applied: (1) Hebeloma crustuliniforme, an ectomycorrhizal partner of spruce; (2) Suillus variegatus, an ectomycorrhizal fungus incompatible with spruce; (3) Heterobasidion annosum, a spruce pathogen. Activity staining after SDS-PAGE and western blotting showed an accumulation of an ionically wall-bound 38-kDa peroxidase isoform. In addition, two covalently wall-bound isoforms (34 and 53 kDa) that could be released from spruce cell walls by cellulase and pectinase treatment were also induced by elicitors from these fungi. Moreover, in cells cultured without auxins all the elicitors triggered a rapid and transient accumulation of ionically wall-bound peroxidases, which reached a maximum activity 48 h after elicitor application. This early and transient peroxidase accumulation was diminished and delayed in cells cultured in the presence of auxins. In contrast, activity of peroxidases released into the culture medium of spruce cells or into the medium of protoplasts was suppressed by the elicitors of Hebeloma crustuliniforme. However, this suppression was attenuated by the action of auxins. It is suggested that under natural conditions, in infected spruce roots, the elicitors of the compatible fungus cause both suppression of the peroxidase (which is secreted to the free space of the roots), and induction of wall-bound and symplasmic peroxidases. On the other hand, auxins synthesized by the fungus could weaken these different elicitor-mediated effects.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 32 (1939), S. 169-175 
    ISSN: 1437-1596
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Type of Medium: Electronic Resource
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