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  • infants  (2)
  • Ankle joint mobility  (1)
  • Circumscribed scleroderma  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Laser-Doppler-Flux-Messungen zur Therapiekontrolle bei zirkumskripter Sklerodermie (1995)
    Springer
    Der Hautarzt 46 (1995), S. 421-424 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Laser-Doppler-Flux ; Kutane Mikrozirkulation ; Morphaea ; Zirkumskripte Sklerodermie ; Therapiekontrolle ; Key words Laser-Doppler flux ; Microcirculation of the skin ; Morphoea ; Circumscribed scleroderma ; Control of therapy results
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A 38-year-old male patient presented with circumscribed scleroderma (10×12 cm) in the left pectoral area. Hyperaemia of the skin in the area of the lilac ring (morphoea) was quantified by means of Laser-Doppler flux (LDF). At the lilac border of the morphoea LDF was increased to 420% of the reference value recorded for the unaffected skin of the contralateral side. Immediately after 13 days of antibiotic therapy (3×10 Mega penicillin G per day, i.v.) LDF normalized, though clinical changes were hardly apparent at this stage. By 6 months later, LDF was still in the normal range, and clinical signs, such as induration and hyperaemic redness, had also significantly improved. LDF measurements allow assessment of the therapeutic response to antibiotic therapy at a very early stage while the clinical situation is still unchanged.
    Notes: Zusammenfassung Wir berichten über einen 38jährigen Patienten mit zirkumskripter Sklerodermie (CS) und einem linkspektoralen Morphaea-Herd. Der Rückgang einer entzündlich gesteigerten Mehrdurchblutung im Areal des Lilac-Rings wurde durch wiederholte Messungen des Laser-Doppler-Flux (LDF) unter Therapie objektiviert. Unmittelbar vor Therapiebeginn sowie am letzten Behandlungstag und nach weiteren 6 Monaten wurde der Laser-Doppler-Flux an denselben Hautarealen im entzündlichen Randbereich, im Zentrum des Morphaea-Herdes sowie im Gesunden rechtspektoral bestimmt. Vor Antibiose fand sich im Lilac-Ring eine auf 420% – im Vergleich zum gesunden rechtspektoralen Referenzareal – gesteigerte Fluxmotion. Nach 13tägiger Therapie mit Penicillin G (3×10 Mega i.v.d) kam es zu einer Normalisierung der pathologisch erhöhten Meßwerte, während klinische Veränderungen zu diesem Zeitpunkt kaum erkennbar waren. Erst 6 Monate später – die LDF-Werte waren immer noch im Bereich der Vergleichswerte gesunder Haut – war klinisch eine deutliche Rückläufigkeit von Induration und Erythem sichtbar. Mit Laser-Doppler-Flux-Messungen kann frühzeitig, bevor klinisch eine Verbesserung diagnostiziert werden kann, das therapeutische Ansprechen nachgewiesen werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050277
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Gefäßsport zur ambulanten Therapie venöser Durchblutungsstörungen der Beine Diagnostische, therapeutische und prognostische Aspekte (1997)
    Springer
    Der Hautarzt 48 (1997), S. 384-390 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Arthrogenes Stauungssyndrom ; Chronische Veneninsuffizienz ; Gefäßsport ; Gelenkbeweglichkeit ; Ulcus cruris ; Muskelpumpe ; Key words Arthrogenic congestive syndrome ; Chronic venous insufficiency ; Physical exercise training ; Ankle joint mobility ; Calf muscle pump ; Venous ulcer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 33 patients with chronic venous incompetence (CVI) caused by primary varicoses or postthrombotic syndrome stage I–III (according to Widmer) the therapeutic benefit of 6 months of medically supervised physical exercise training was documented. During the training penud there was an improvement in subjective complains such as pain and tendency for edema in the legs. Mobility in the upper ankle joint was improved asuss as venous drainage function. Clinical benefit was achieved in the reduction of ulcer size; 7 of 10 ulcers completely healed. Medically supervised physical exercise training and optimized compression therapy are basic therapeutic approaches in conservative treatment in chronic venous insufficiency. Costs are covered by the patient’s health insurance company in Germany, as long as the exercise training is medically supervised.
    Notes: Zusammenfassung In einer klinischen Untersuchung bei 33 Patienten mit chronischer Veneninsuffizienz aufgrund primärer Varikose oder eines postthrombotischen Syndroms in den klinischen Stadien I bis III nach Widmer konnte der Therapieerfolg eines halbjährigen krankheitsspezifischen ambulanten Bewegungstrainings dokumentiert werden. Während des Trainings kam es zu einer deutlichen Besserung stauungsbedingter subjektiver Beschwerden wie Schmerzen und Ödemneigung sowie zu einer Verbesserung von Sprunggelenkbeweglichkeit und venöser Abpumpleistung. Der klinische Erfolg zeigte sich in einer kompletten Abheilung venöser Ulzera bei 7 von 10 Patienten. In Verbindung mit einer optimierten Kompressionstherapie stellt die Gefäßsporttherapie eine effiziente und kostengünstige Basistherapie bei der CVI dar. Auf der Grundlage des novellierten Deutschen Behindertensportabkommens aus dem Jahre 1994 werden die Kosten von den gesetzlichen Krankenkassen getragen, solange das Training unter qualifizierter Anleitung indiziert ist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050598
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Genetic and Developmental Influences on Infant Mouse Ultrasonic Calling. I. A Diallel Analysis of the Calls of 3-Day Olds (1997)
    Springer
    Behavior genetics 27 (1997), S. 133-143 
    Details
    ISSN: 1573-3297
    Keywords: Mice ; ultrasounds ; ultrasonic calls ; infants ; diallel cross ; individual differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Ultrasonic calls produced by young mice reliably elicit investigation and retrieval by adults. While there are large individual differences in the characteristics of these calls, little work has been done to partition that variation. We completed a 4 × 4 diallel cross and Hayman analyses on several characteristics of these cries. The major result was the detection of directional dominance toward a higher rate of calling, longer calls, and calls of lower overall frequency with a greater bandwidth. Within the context of biometrical genetic theory, we conclude that calls with such characteristics may have important fitness value. Extending this idea, we propose that within the population sampled for this study (the animals of the four inbred strains and 12 F1 hybrid groups), the calls most effectively eliciting investigation and retrieval would be calls with the average hybrid values of the diallel cross.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1025637408900
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Genetic and Developmental Influences on Infant Mouse Ultrasonic Calling. II. Developmental Patterns in the Calls of Mice 2–12 Days of Age (1998)
    Springer
    Behavior genetics 28 (1998), S. 315-325 
    Details
    ISSN: 1573-3297
    Keywords: Mice ; ultrasonic calls ; infants ; individual differences ; signatures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Infant house mice, Mus musculus, produce ultrasonic calls that reliably lead to retrieval by adult mice. While individual differences in calls have been demonstrated both among and within species, the influences of age and sex on call characteristics have not been systematically investigated in mice. This study examined the influences of age, sex, and genotype (inbred versus hybrid) on the rate, length, and frequency characteristics of the calls of 486 male and female mice from 2 to 12 days of age. Rate of calling followed a shallow inverted U-shaped function across days. Call lengths decreased and call frequency characteristics increased, in a linear manner, with age. Females emitted fewer calls, with a smaller bandwidth, at some ages than males. Hybrid pups produced more calls of greater length and a lower frequency than inbred pups. These results indicate the presence of cues that could allow adult mice to behave differentially toward pups as a function of their age and sex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021679615792
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    Paper (German National Licenses)
    Fulltext
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