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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 67 (1989), S. 304-307 
    ISSN: 1432-1440
    Keywords: Hyperthyroidism ; Follicular thyroid carcinoma ; Radioiodine scan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A well differentiated carcinoma of the thyroid is usually less productive with respect to thyroid hormones than normal thyroid tissue. Very rarely, it happens though that a metastatic follicular carcinoma of the thyroid produces hyperthyroidism as the following example illustrates. In our patient with follicular thyroid carcinoma the radioiodine scan demonstrated an increased uptake of123I in the right thyroid lobe but also in a lung metastasis, even before thyroidectomy. In contrast, the iodine uptake of the left — normal — thyroid lobe was suppressed. Following thyroidectomy the levels of the thyroid hormones were normal and only dropped into the hypothyroid range after the beginning of the therapy with radioiodine. Hence we conclude that the metastases of a thyroid carcinoma can attain the hormone secretion of a normal thyroid gland and take up more radioiodine than normal thyroid tissue.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Psychiatry Research 29 (1989), S. 331-333 
    ISSN: 0165-1781
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. To evaluate the role of endoscopic retrograde cholangiography (ERC) before laparoscopic cholecystectomy, we compared the frequency of concomitant common bile duct stones, their clinical outcome, and the frequency of bile duct injury between a group of 128 patients with routine preoperative ERC (group A) and 1010 patients with selective ERC (group B). Overall, 48 patients (4.2%) had duct stones, but the predictive signs were absent in six of them (12.5%). The stones were demonstrated by ERC and removed by sphincterotomy in all 11 patients in group A. Of 37 patients in group B, 22 were diagnosed by selective ERC and underwent endoscopic removal. Of four patients whose stones were found by operative cholangiography, one had immediate open surgery, another passed a stone spontaneously, and the other two underwent postoperative sphincterotomy, which failed in one. The stones were not recognized until pain recurred in the remaining 11 patients. Sphincterotomy was successful in nine patients but failed in the other two. Thus postoperative sphincterotomy failed in 3 of 13 patients (23%), necessitating open surgery. Forty-two patients overall (3.7%) had aberrant biliary tract anatomy, which did not lead to bile duct injury in any of the patients. Morbidity of routine ERC (3.1%) was lower than that of selective ERC (7.4%) ( p 〈 0.05). It should be noted that a certain proportion of duct stones may be missed by selective ERC, necessitating laparotomy when sphincterotomy fails. The routine use of preoperative ERC may be justified at institutions where the expertise is available, at least until laparoscopic lithotomy becomes easy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 339 (1975), S. 321-326 
    ISSN: 1435-2451
    Keywords: Bone carcinoma ; scintigraphy ; Radiopharmaceutical agents ; Boneseeting ; Primäre Knochentumoren ; Szintigraphie ; osteotrope Radiopharmaka
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit Einführung kurzlebiger osteotroper Radionuklide hat die Knochenszintigraphie wesentlich an Bedeutung gewonnen. Da anhand von Speichererhöhung im Szintigramm keine differential-diagnostischen Aussagen gemacht werden können, ist das Hauptanwendungsgebiet die Suche nach Knochenmetastasen. Unter überlegter Indikationsstellung kann jedoch auch bei primären Knochentumoren die Szintigraphie sowohl die Diagnostik ergänzen als auch die Therapieplanung positiv beeinflussen. Anhand von klinischen Beispielen werden die Anwendungsbereiche der Skeletszintigraphie aufgezeigt.
    Notes: Summary Bone scintigraphy has improved greatly since the introduction of bone-seeing short-lived radionuclides. The main field of interest is the search for metastases into bone. The uncharacteristic accumulation of radiopharmaceutical agents in different bone lesions makes specific diagnostic evaluations unlikely. With careful selection of cases, however, scintigraphy can also be used in primary bone tumors as a supplementary means of diagnosis as well as having a positive effect on treatment. Clinical examples are presented to demonstrate the range of application of bone scintigraphy.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 74 (1970), S. 349-354 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit kurzer Zeit steht für nuclearmedizinische Untersuchungen ein neues Detektorsystem, die Positronenkamera, zur Verfügung. Um dieses Kamerasystem einsetzen zu können, ist es notwendig, bei den Untersuchungen Radiopharmaka zu benutzen, die mit Positronenstrahlern markiert sind. Für die Hirnseintigraphie erschien uns der [Al18F6]3−-Komplex, dessen Pharmakokinetik wir in früheren Arbeiten eingehend untersucht haben, auf Grund seiner schnellen Gewebeclearance und seines dem [99TcmO4]1−-Komplex ähnlichen Verhaltens bezüglich der Bluthirnschrankenfunktion für die Hirntumordiagnostik geeignet zu sein. Erste vergleichende Untersuchungen bei Patienten mit Hirntumoren zeigten, daß diese Tumoren mit dem 18F-Komplex ähnlich gut nachgewiesen werden können wie mit 99Tcm-Pertechnetat. Damit sind die Voraussetzungen für eine Tomoscintigraphie des Gehirns mit der Positronenkamera gegeben.
    Notes: Summary A new detector system, the positron camera, has been recently introduced into Nuclear Medicine. For this camera system it is necessary to use in the examinations radiopharmaceutica, which are labelled with positron emitters. The [Al18F6]3−-complex, which we have examined in previous studies, seemed to be suitable for brain scintigraphy because it is cleared quickly from tissues and because its effect on the blood-brain-barrier is similar to that of the [99TcmO4]1−-complex. First comparative investigations with brain tumour patients showed that brain tumours can be detected as well with the 18F-complex as with the 99Tcm-complex. By using the 18F-compound with the positron camera tomoscintigraphy of the brain can be performed.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 35 (1957), S. 110-119 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. In einem klinischen Krankengut von 3750 Diabetikern fanden wir in etwa 2,5% eine Retinopathia proliferans (R.p.), bei weiblichen Patienten häufiger als bei männlichen. 2. Die R.p. manifestiert sich in der Regel frühestens um das 18.–20. Lebensjahr. Sie wird um so häufiger getroffen und verläuft um so maligner, je früher der Diabetes und dann eine einfache Retinopathie manifest wurde. 3. Die R.p. wird gewöhnlich erst nach 10jähriger Diabetesdauer gefunden. 4. Zwischen Iridopathia diabetica und R.p. bestehen enge Beziehungen. 5. Die R.p. ist mit einer Nephropathie vergesellschaftet, deren Verlauf die Lebensdauer des Kranken bestimmt. Daher werden die Endstadien der R.p. meist nicht erlebt oder nur kurze Zeit überlebt.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 6 (1978), S. 233-234 
    ISSN: 1432-1998
    Keywords: Wilms' tumour ; Bone metastasis ; Bone scanning ; Cold lesions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Isolated mandibular metastasis in Wilms' tumour resulted in cold lesion on a bone scan.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 8 (1979), S. 254-256 
    ISSN: 1432-1998
    Keywords: Chronic myelogenous leukemia ; Bone lesions ; Blastic crisis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Report of a 13-year-old boy who developed osteolytic lesions in the chronic phase of myelogenous leukemia. Five months later a blastic crisis followed.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 73 (1972), S. 25-32 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Unter Darstellung der Diagnostik und der röntgenologischen Differentialdiagnostik wird auf die Besonderheiten in Therapie und Prognose bei am Becken oder in langen Röhrenknochen lokalisierten Chondromen eingegangen. Wie die Beobachtungen zeigen, kann bei diesen semimalignen Geschwülsten ausschließlich durch eine frühzeitige Radikaloperation eine günstige Prognose erzielt werden.
    Notes: Summary The prognosis of chondroma in pelvic or long tubular bones is different from that of other locations and these tumors therefore call for specific therapeutic measurements. It has been shown that only early radical surgical treatment will ensure a favorable prognosis in these semimalignant tumors. Some general diagnostic and X-ray differential diagnostic aspects are discussed as well.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Hallervorden-Spatz-Krankheit ; Parkinsonsyndrom ; MRT ; 123J-β-CIT ; 123J-IBZM ; Keywords Hallervorden-Spatz Disease ; Parkinson's syndrome ; MRI ; 123I-β-CIT ; 123I-IBZM
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Hallervorden-Spatz disease (HSD), a rare extrapyramidal motor illness, is usually only confirmed after death. In vivo diagnosis has relied hitherto on the combination of typical magnetic resonance imaging (MRI) findings (the “eye of the tiger” sign) and heterogeneous clinical symptoms of movement disorder which have been regarded as almost pathognomonic. We report on the diagnostic contribution of 123J-β-CIT single photon emission computed tomography (SPECT) and 123J-IBZM SPECT in akinetic-rigid Parkinson's syndrome occurring in a case of HSD. In contrast to Parkinson's disease and multisystem atrophies, the results of both tests were normal. This constellation of findings shows that the degeneration lies primarily outside the nigrostriatal system, supporting arguments for the nosologic distinction of HSD from other extrapyramidal illnesses.
    Notes: Zusammenfassung Die Diagnose der Hallervorden-Spatz-Krankheit (HSD), einer seltenen extrapyramidal-motorischen Erkrankung, konnte gewöhnlich erst postmortal gesichert werden. Bislang galt der typische MRT-Befund mit dem “Tigerauge-Zeichen” in Kombination mit der heterogen klinischen Symptomatik von Bewegungsstörungen als nahezu pathognomonisch und diente zur Diagnosestellung zu Lebzeiten. In der vorliegenden Kasuistik soll der diagnostische Beitrag von 123J-β-CIT und 123J-IBZM-SPECT bei einem akinetisch-rigiden Parkinsonsyndrom im Rahmen einer HSD dargestellt werden. Für beide Untersuchungen wurden im Gegensatz zum M. Parkinson und Multisystematrophien Normalbefunde gefunden. Diese Befundkonstellation zeigt einerseits, dass die Degeneration primär außerhalb des nigrostriatalen Systems liegt, und andererseits unterstützt sie die Diskussion der nosologischen Abgrenzung der HSD von anderen extrapyramidalen Erkrankungen.
    Type of Medium: Electronic Resource
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