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  • 1
    ISSN: 0165-1781
    Keywords: Affective disorder ; circadian rhythm ; growth hormone releasing hormone ; melancholia ; polysomnography ; sleep
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0165-1781
    Keywords: EEG mapping in Alzheimer's disease ; Geriatric psychiatry ; aging ; gender effects
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Transkranielle Magnetstimulation ; Elektrokrampftherapie ; Depression ; Therapie ; Key words Transcranial magnetic stimulation ; Electro convulsive therapy ; Depression ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Transcranial magnetic stimulation (TMS) has been used since a decade to investigate the central motor system in the neurological routine diagnostic. From this experience TMS has prooved to be a save and well tolerated procedure. In the past few years several studies investigated TMS to electrically stimulate deeper brain regions to find antidepressive effects in analogy to electro convulsive therapy (ECT). This could be of great advantage as TMS is well tolerated and does not require general anesthesia. There have been some case reports and also some controlled clinical studies on TMS as a therapeutic tool. The results of these studies have been promising. Many questions regarding technical and clinical aspects remain to be answered. In the future however TMS could be a valuable addition in the treatment of depression.
    Notes: Zusammenfassung Die transkranielle Magnetstimulation (TMS) ist ein Verfahren, das seit nunmehr einer Dekade in der neurologischen Diagnostik zur Untersuchung der motorischen Bahnsysteme routinemäßig eingesetzt wird. Aus dieser Zeit ist die TMS bezüglich der Sicherheit in der Anwendung am Menschen gut untersucht und hat sich als sicher und nebenwirkungsfrei erwiesen. Seit wenigen Jahren wird die Möglichkeit untersucht, mittels der TMS nichtinvasiv tiefere Hirnregionen elektrisch zu stimulieren und so, in Analogie zur Elektrokrampftherapie, eine antidepressive Wirkung zu erzielen. Dies hätte große Vorteile, da dieses Verfahren schonend und ohne Narkose angewendet werden kann. Mehrere Einzelfallanwendungen, aber auch schon mehrere klinisch kontrollierte Studien lassen z. Z. die begründete Hoffnung zu, daß dieses Verfahren zu einer Erweiterung des Spektrums antidepressiver Behandlungsverfahren führen könnte.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of trauma 24 (1998), S. 253-257 
    ISSN: 1615-3146
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of trauma 25 (1999), S. 87-89 
    ISSN: 1615-3146
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 246 (1996), S. 197-202 
    ISSN: 1433-8491
    Keywords: QEEG ; Tourette's syndrome ; Cortical activation ; Motor dysfunction ; Cognitive dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gilles de la Tourette's syndrome (TS) is a neurobehavioral disorder of childhood onset that is characterized by motor and vocal tics and associated behavioral disturbances including obsessive-compulsive symptoms. We performed 30 channel quantitative electroencephalograms (EEGs) on 13 Tourette patients and 26 controls and studied both resting and manumotor/music perception activation conditions. Resting EEGs did not show any differences between patients and controls, as known from the literature. However, during simple and complex hand movements, as well as music perception tasks, there were subtle differences predominantly in alpha frequency. They suggested reduced brain activation during motor tasks in frontal and central regions, and on music perception in temporal and parietal regions, respectively. These findings may add evidence to the functional neuroanatomy of Tourette syndrome, affecting more areas than disturbed motor circuits.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1433-8491
    Keywords: Motor training programs ; Motor dysfunction in psychosis-additional treatment in psychosis-motor brain dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Parts I–III of this series used psychometric assessment of motor performance in psychiatric patients and indicated a “psychotic-motor syndrome” (PMS) in schizophrenic and affective psychoses, which was not found in “neurotic”/reactive or healthy persons. Part IV yielded signs of concomitant brain dysfunction in these patients, demonstrated by EEG mapping as well as other (SPECT/PET) neuroimaging methods. Apart from this “basic science” interest into the pathophysiology of endogenous psychoses we engaged in the development of motor training programs using the PMS as “target” syndrome. We hypothesized, that motor training would not only improve disturbed motor behaviour, but ameliorate other symptoms of psychopathology also. These assumptions were supported in the first two independent studies involvingn=45 andn=31 ICD-9 mono-and/or bipolar endogenous depressed patients, respectively (the studies on schizophrenic patients being reported finally as part VI of this series, along with the final version of our modified motor test battery). Examples of the motor training programs are provided in this paper, although the final version of the complete programs will be published separately for space reasons and for better availability for routine clinical use.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 69 (1998), S. 909-912 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Amnesie ; Dissoziative Störung ; Diffusionsimaging ; SPECT ; Key words Amnesia ; Dissociative disorder ; Diffusion MRI ; SPECT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The differential diagnosis of psychogenic vs. organic amnestic syndromes may cause difficulty in certain cases. Here, we report a case of psychogenic amnesia which occurred after alcohol intoxication and mild head trauma. The initial memory deficit was very severe consisting of near-complete retrograde amnesia and anterograde amnesia covering 12 hours. The deficits resolved within a 4-week period of time. Brain CT and MRI scans revealed two circumscribed lesions of the right temporal lobe which were interpreted as old posttraumatic lesions. To ascertain the diagnosis, diffusion-weighted MR imaging (DWI) and brain perfusion SPECT were performed. The basal temporal lobes neither showed focal changes of perfusion, nor enhanced signal intensity on DWI as has been recently reported in patients with transient global amnesia. Later, the dissociative nature of the disorder could be confirmed by the exploration of recent psychological conflicts and the delayed type of recovery. We regard diffusion-weighted MRI as a powerful means to differentiate acute amnestic syndromes.
    Notes: Zusammenfassung Die Differenzierung zwischen psychogener und organisch bedingter Amnesie kann im Einzelfall schwierig sein. Hier wird ein Fall von dissoziativer Amnesie mitgeteilt, der im Anschluß an eine Alkoholintoxikation und ein leichtes Kopftrauma auftrat. Das amnestische Syndrom war initial so schwer, daß eine fast komplette retrograde Amnesie und eine anterograde Amnesie von etwa 12 h nachweisbar war. Die Gedächtnisverluste bildeten sich nur zögernd über insgesamt 4 Wochen zurück. Bildgebend fanden sich in der CT und MRT 2 ältere fokale, vermutlich posttraumatische Läsionen im rechten Temporallapppen ohne Nachweis frischer Traumafolgen. Um die Diagnose zu sichern, führten wir die diffusionsgewichtete MR-Bildgebung und Hirnperfusions-SPECT durch. Wir konnten in den basalen Temporallappen weder eine Perfusionsstörung noch Signalveränderungen im Diffusionsbild nachweisen, wie dies bei Patienten mit transitorisch globaler Amnesie beobachtet wurde. Der protrahierte Verlauf sowie die Exploration erheblicher psychischer Konflikte bestätigten später die Diagnose einer dissoziativen Störung. Das diffusionsgewichtete MR-Imaging ist somit ein wertvolles Instrument, um in der Akutphase amnestische Syndrome differentialdiagnostisch einzuordnen.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 47 (1988), S. 199-203 
    ISSN: 1432-0630
    Keywords: 81.15 Gh ; 52.90+z ; 68.55+b
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The adhesion of copper to PTFE has been studied with regard to the influence of a pretreatment in discharges of reactive gases, such as O2 and CF4/O2, and a subsequent deposition of thin metallic interlayers of Pd, Pt, Au, and Cu by PECVD methods. Adhesion forces could be enhanced by about the factor of 10 compared with merely pretreated surfaces up to 5 N/mm, which, as scanning electron micrographs prove, corresponds to the tensile strength of the bulk material. SIMS spectra of the back surface of a peeled copper stripe show the typical signals of PTFE. The thermal stability of the layers was established by dipping the samples into a tin bath of 540 K. The enhanced adhesion is not only due to the changes in surface morphology by etching. It can be attributed to chemical effects, i. e. chemical bonds between substrate atoms and the interlayer, and physical effects, caused by implantation of metal ions into the upper surface layers accompanied by a probable electron transfer from PTFE to metal.
    Type of Medium: Electronic Resource
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