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  • 2015-2019  (10)
  • 2017  (3)
  • 2016  (7)
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  • 2015-2019  (10)
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  • 1
    Publication Date: 2020-08-05
    Description: The problem of allocating operating rooms (OR) to surgical cases is a challenging task, involving both combinatorial aspects and uncertainty handling. In this article, we formulate this problem as a job shop scheduling problem, in which the job durations follow a lognormal distribution. We propose to use a cutting-plane approach to solve a robust version of this optimization problem. To this end, we develop an algorithm based on fixed-point iterations to solve the subproblems that identify worst-case scenarios and generate cut inequalities. The procedure is illustrated with numerical experiments based on real data from a major hospital in Berlin.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 2
    Publication Date: 2020-08-05
    Description: We propose an algorithm to approximate the distribution of the completion time (makespan) and the tardiness costs of a project, when durations are lognormally distributed. This problem arises naturally for the optimization of surgery scheduling, where it is very common to assume lognormal procedure times. We present an analogous of Clark's formulas to compute the moments of the maximum of a set of lognormal variables. Then, we use moment matching formulas to approximate the earliest starting time of each activity of the project by a shifted lognormal variable. This approach can be seen as a lognormal variant of a state-of-the-art method used for the statistical static timing analysis (SSTA) of digital circuits. We carried out numerical experiments with instances based on real data from the application to surgery scheduling. We obtained very promising results, especially for the approximation of the mean overtime in operating rooms, for which our algorithm yields results of a similar quality to Monte-Carlo simulations requiring an amount of computing time several orders of magnitude larger.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 3
    Publication Date: 2021-01-22
    Description: We study an extension of the shortest path network interdiction problem and present a novel real-world application in this area. We consider the problem of determining optimal locations for toll control stations on the arcs of a transportation network. We handle the fact that drivers can avoid control stations on parallel secondary roads. The problem is formulated as a mixed integer program and solved using Benders decomposition. We present experimental results for the application of our models to German motorways.
    Language: English
    Type: conferenceobject , doc-type:conferenceObject
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  • 4
    Publication Date: 2020-08-05
    Description: We present the problem of planning mobile tours of inspectors on German motorways to enforce the payment of the toll for heavy good trucks. This is a special type of vehicle routing problem with the objective to conduct as good inspections as possible on the complete network. In addition, we developed a personalized crew rostering model, to schedule the crews of the tours. The planning of daily tours and the rostering are combined in a novel integrated approach and formulated as a complex and large scale Integer Program. The main focus of this paper extends our previous publications on how different requirements for the rostering can be modeled in detail. The second focus is on a bi-criteria analysis of the planning problem to find the balance between the control quality and the roster acceptance. Finally, computational results on real-world instances show the practicability of our method and how different input parameters influence the problem complexity.
    Language: English
    Type: article , doc-type:article
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  • 5
    Publication Date: 2020-08-05
    Description: The problem of allocating operating rooms (OR) to surgical cases is a challenging task, involving both combinatorial aspects and uncertainty handling. We formulate this problem as a parallel machines scheduling problem, in which job durations follow a lognormal distribution, and a fixed assignment of jobs to machines must be computed. We propose a cutting-plane approach to solve the robust counterpart of this optimization problem. To this end, we develop an algorithm based on fixed-point iterations that identifies worst-case scenarios and generates cut inequalities. The main result of this article uses Hilbert's projective geometry to prove the convergence of this procedure under mild conditions. We also propose two exact solution methods for a similar problem, but with a polyhedral uncertainty set, for which only approximation approaches were known. Our model can be extended to balance the load over several planning periods in a rolling horizon. We present extensive numerical experiments for instances based on real data from a major hospital in Berlin. In particular, we find that: (i) our approach performs well compared to a previous model that ignored the distribution of case durations; (ii) compared to an alternative stochastic programming approach, robust optimization yields solutions that are more robust against uncertainty, at a small price in terms of average cost; (iii) the \emph{longest expected processing time first} (LEPT) heuristic performs well and efficiently protects against extreme scenarios, but only if a good prediction model for the durations is available. Finally, we draw a number of managerial implications from these observations.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
    Format: application/pdf
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  • 6
    Publication Date: 2021-01-19
    Description: We propose (Mixed Integer) Second Order Cone Programming formulations to find approximate and exact $D-$optimal designs for $2^k$ factorial experiments for Generalized Linear Models (GLMs). Locally optimal designs are addressed with Second Order Cone Programming (SOCP) and Mixed Integer Second Order Cone Programming (MISOCP) formulations. The formulations are extended for scenarios of parametric uncertainty employing the Bayesian framework for \emph{log det} $D-$optimality criterion. A quasi Monte-Carlo sampling procedure based on the Hammersley sequence is used for integrating the optimality criterion in the parametric region. The problems are solved in \texttt{GAMS} environment using \texttt{CPLEX} solver. We demonstrate the application of the algorithm with the logistic, probit and complementary log-log models and consider full and fractional factorial designs.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 7
    Publication Date: 2020-08-05
    Description: Let G be a directed acyclic graph with n arcs, a source s and a sink t. We introduce the cone K of flow matrices, which is a polyhedral cone generated by the matrices $\vec{1}_P\vec{1}_P^T\in\RR^{n\times n}$, where $\vec{1}_P\in\RR^n$ is the incidence vector of the (s,t)-path P. We show that several hard flow (or path) optimization problems, that cannot be solved by using the standard arc-representation of a flow, reduce to a linear optimization problem over $\mathcal{K}$. This cone is intractable: we prove that the membership problem associated to $\mathcal{K}$ is NP-complete. However, the affine hull of this cone admits a nice description, and we give an algorithm which computes in polynomial-time the decomposition of a matrix $X\in \operatorname{span} \mathcal{K}$ as a linear combination of some $\vec{1}_P\vec{1}_P^T$'s. Then, we provide two convergent approximation hierarchies, one of them based on a completely positive representation of~K. We illustrate this approach by computing bounds for the quadratic shortest path problem, as well as a maximum flow problem with pairwise arc-capacities.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 8
    Publication Date: 2020-08-05
    Description: An algorithm based on a delayed constraint generation method for solving semi-infinite programs for constructing minimax optimal designs for nonlinear models is proposed. The outer optimization level of the minimax optimization problem is solved using a semidefinite programming based approach that requires the design space be discretized. A nonlinear programming solver is then used to solve the inner program to determine the combination of the parameters that yields the worst-case value of the design criterion. The proposed algorithm is applied to find minimax optimal designs for the logistic model, the flexible 4-parameter Hill homoscedastic model and the general nth order consecutive reaction model, and shows that it (i) produces designs that compare well with minimax $D-$optimal designs obtained from semi-infinite programming method in the literature; (ii) can be applied to semidefinite representable optimality criteria, that include the common A-, E-,G-, I- and D-optimality criteria; (iii) can tackle design problems with arbitrary linear constraints on the weights; and (iv) is fast and relatively easy to use.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 9
    Publication Date: 2022-07-19
    Description: Statistical methods to design computer experiments usually rely on a Gaussian process (GP) surrogate model, and typically aim at selecting design points (combinations of algorithmic and model parameters) that minimize the average prediction variance, or maximize the prediction accuracy for the hyperparameters of the GP surrogate. In many applications, experiments have a tunable precision, in the sense that one software parameter controls the tradeoff between accuracy and computing time (e.g., mesh size in FEM simulations or number of Monte-Carlo samples). We formulate the problem of allocating a budget of computing time over a finite set of candidate points for the goals mentioned above. This is a continuous optimization problem, which is moreover convex whenever the tradeoff function accuracy vs. computing time is concave. On the other hand, using non-concave weight functions can help to identify sparse designs. In addition, using sparse kernel approximations drastically reduce the cost per iteration of the multiplicative weights updates that can be used to solve this problem.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 10
    Publication Date: 2022-07-19
    Language: English
    Type: conferenceobject , doc-type:conferenceObject
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