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  • 2000-2004  (3)
  • 1975-1979  (16)
  • 1
    Electronic Resource
    Electronic Resource
    Pattern formation in a ts-cell-lethal mutant ofDrosophila: The range of phenotypes induced by larval heat treatments (1977)
    Springer
    Development genes and evolution 183 (1977), S. 41-59 
    Details
    ISSN: 1432-041X
    Keywords: Imaginal discs ; Pattern formation ; Cell death ; Duplication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We describe the range of phenotypes caused by cell death when larvae of the heat-sensitive cell-lethal mutant,l(1)ts726 ofDrosophila, are subjected to heat treatment at different stages of development. When the treatment extends into the pupal period, certain bristles fail to develop but the disc derivatives are otherwise normal. Earlier treatments cause the replacement of sets of leg and eye-antennal markers by mirror image duplications of neighbouring sets. The results are compared in detail with those expected under a gradient model proposed earlier to account for the phenotype. It is found that although the results for the second leg are in excellent agreement with the predictions of the model, a more elaborate hypothesis is necessary to account for the eye-antennal disc data. Abnormal head patterns fall into several distinct categories, any one of which could be explained by postulating the existence of a gradient, if other categories did not also occur. The markers affected in each case belong to overlapping sets, and each category of pattern can be induced by heat treatments administered throughout the temperature-sensitive period. The statistical distribution of the data is such that only one category of pattern would be detected in a small scale experiment. The possible implications relative to pattern formation in normal development are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00849033
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Analysis of differential gene expression supports a role for amyloid precursor protein and a protein kinase C substrate (MARCKS) in long-term memory (2003)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 17 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Previous work has identified the intermediate and medial part of the hyperstriatum ventrale (IMHV) as a region of the chick brain storing information acquired through the learning process of imprinting. We have examined in this brain region changes in expression of candidate genes involved in memory. Chicks were exposed to a rotating red box and the strength of their preference for it, a measure of learning, determined. Brain samples were removed ≈24 h after training. Candidate genes whose expressions were different in IMHV samples derived from strongly imprinted chicks relative to those from chicks showing little or no learning were identified using subtractive hybridization. The translation products of two candidate genes were investigated further in samples from the left and right IMHV and from two other brain regions not previously implicated in imprinting, the left and right posterior neostriatum. One of the proteins was the amyloid precursor protein (APP), the other was myristoylated alanine rich C kinase substrate (MARCKS). In the left IMHV the levels of the two proteins increased with the strength of learning. The effects in the right IMHV were not significantly different from those in the left. There were no effects of learning in the posterior neostriatum. This is the first study to relate changes in the amounts of MARCKS and APP proteins to the strength of learning in a brain region known to be a memory store and demonstrates that the systematic identification of protein molecules involved in memory formation is possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9568.2003.02539.x
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  • 3
    Electronic Resource
    Electronic Resource
    Towards fully parallel aerospace simulations on unstructured meshes (2001)
    Bradford : Emerald
    Engineering computations 18 (2001), S. 347-376 
    Details
    ISSN: 0264-4401
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Technology
    Notes: A general philosophy is presented in which all the modules within the computational cycle are parallelised and executed on parallel computer hardware, thereby avoiding the creation of computational bottlenecks. In particular, unstructured mesh generation with adaptation, computational fluid dynamics and computational electromagnetic solvers and the visualisation of grid and solution data are all performed in parallel. In addition, all these modules are embedded within a parallel problem solving environment. This paper will provide an overview of these developments. In particular, details of the parallel mesh generator, which has been used to generate meshes in excess of 100 million elements, will be given. A brief overview will be presented of the approach used to parallelise the solvers and how large data sets are interrogated and visualised on distributed computer platforms. Details of the parallel adaptation algorithm will be presented. These parallel component modules are linked using CORBA communication to provide an integrated parallel approach for large scale simulations. Several examples are given of the approach applied to the simulation of large aerospace calculations in the field of aerodynamics and electromagnetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/02644400110386984
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The simulation of electromagnetic scattering in piecewise homogeneous media using unstructured grids (2000)
    Springer
    Computational mechanics 25 (2000), S. 438-447 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  This paper presents a method for simulating, in the time domain, the scattering of electromagnetic waves in piecewise homogeneous media. The method employs an explicit Taylor–Galerkin approach, implemented on a general unstructured triangular grid, with the electric and magnetic fields approximated in a continuous piecewise linear fashion. All boundary and material interface conditions are weakly applied in an integral form, following a characteristic decomposition of the solution. A number of simple examples, for which exact scattering width distributions are available, are included to demonstrate the numerical performance of the proposed procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660050491
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  • 5
    Electronic Resource
    Electronic Resource
    Localization of a new neuroleptic in the pituitary gland of the rat (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 1485-1486 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: summary The14C-labelled, substituted benzamide neuroleptic Tiapride has been found to accumulate transiently in the pituitary gland of the rat following a single dose, and a prolonged retention of the drug was observed in the pars intermedia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01918823
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  • 6
    Electronic Resource
    Electronic Resource
    Pentobarbital: Presynaptic effect in the squid giant synapse (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 487-488 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In concentrations that produced synaptic blockade in the squid giant synapse, sodium pentobarbital produced a dose-related, reversible decrease of the ‘calcium spike’ of the presynaptic terminal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01922226
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    A re-examination of the fracture mechanics energy balance for elastic-perfectly plastic materials (1977)
    Springer
    International journal of fracture 13 (1977), S. 553-555 
    Details
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00034262
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  • 8
    Electronic Resource
    Electronic Resource
    The effects of overall composition and monomer sequence distribution on the infrared carbonyl stretching frequencies of ethylene-vinylacetate and styrene-vinylacetate copolymers (1979)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 17 (1979), S. 2783-2790 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The vinyl acetate centered triad fractions of some free radically prepared ethylene-vinyl acetate and styrene-vinyl acetate copolymers have been determined from the patterns of vinyl acetate methine carbon peaks in their 13C nuclear magnetic resonance (NMR) spectra. The positions and shapes of the carbonyl bands in the infrared (IR) absorption spectra of the copolymers recorded in chloroform are shown to depend on the compositions of the copolymers and on the proportions of the various vinyl acetate centered triads. Infrared absorption measurements may thus be used in part to characterize the monomer sequence distributions of these copolymers.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1979.170170915
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  • 9
    Electronic Resource
    Electronic Resource
    Linear differential equations with periodic coefficients, 2 volumes, V. A. Yakubovich and V. M. Starzhinskii, Wiley, New York, 1975. No. of pages: 839. Price: £20.60 (1976)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 10 (1976), S. 976-976 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620100430
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  • 10
    Electronic Resource
    Electronic Resource
    Advanced Engineering Mathematics, A. J. Bajpai, L. R. Mustoe and D. Walker, Wiley, London, 1977. No. of pages 578. Price £11·50, $22·00, paper £4·75, $10·00 (1977)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 11 (1977), S. 1898-1898 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620111212
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    Paper (German National Licenses)
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