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  • 1
    ISSN: 1432-2242
    Keywords: RFLP ; Potato ; Tomato ; Genetic maps
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary An RFLP linkage map of the potato is presented which comprises 304 loci derived from 230 DNA probes and one morphological marker (tuber skin color). The self-incompatibility locus of potato was mapped to chromosome I, which is homoeologous to tomato chromosome I. By mapping chromosome-specific tomato RFLP markers in potato and, vice versa, potato markers in tomato, the different potato and tomato RFLP maps were aligned to each other and the similarity of the potato and tomato genome was confirmed. The numbers given to the 12 potato chromosomes are now in accordance with the established tomato nomenclature. Comparisons between potato RFLP maps derived from different genetic backgrounds revealed conservation of marker order but differences in chromosome and total map length. In particular, significant reduction of map length was observed in interspecific compared to intraspecific crosses. The distribution of regions with distorted segregation ratios in the genome was analyzed for four potato parents. The most prominent distortion of recombination was found to be caused by the self-incompatibility locus.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 119-121 (Jan. 1993), p. 117-124 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 4 (1994), S. 371-376 
    ISSN: 1432-1084
    Keywords: Contrast media ; Gastrointestinal tract ; Infants ; Iotrolan ; Radiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over the past 5 years we have used the new dimeric, non-ionic, water-soluble contrast agent iotrolan (Isovist-300) in 370 studies of the paediatric gastrointestinal tract. Iotrolan is by far the best accepted and tolerated contrast agent for young children. Because of its iso-osmolality it can be used without dilution. No ill effects were reported in cases of aspiration or perforation. In all studies very high contrast images were obtained and the required diagnostic information was provided. The only disadvantage of iotrolan is its present high price. However, in view of the small volumes required in children (10 ml is sufficient in 59% and 20 ml sufficient in 92% of investigations) this should not be a major obstacle to its use. Iotrolan promotes a much greater readiness among paediatricians and paediatric surgeons to have gastrointestinal studies performed on very small and very sick babies.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 20 (1990), S. 353-354 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Report of a pediatric case with pulmonary arteriovenous fistula (PAVF) in hereditary hemorrhagic teleangiectasia (HHT), primary suspected by ultrasound. There is a characteristic sonographic feature of the complex type of PAVF revealing septations in contrast of the simple type. The diagnosis was established by angiography.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Canavan disease (CD) is a rare leukodystrophy which is lethal in infancy or early childhood. The underlying biochemical abnormality in CD is a hereditary deficiency ofN-aspartoacylase transmitted in an autosomal recessive fashion. We report on the ultrasound (US), CT, and MRI findings of three unrelated boys with biochemically confirmed CD. At 6 and 9 months of age, two CD patients with rapid neurological deterioration showed markedly enhanced acoustic attenuation of the white matter with the exception of the corpus callosum, giving the appearance of a reversed pattern of echogenicity of cortical gray and subcortical white matter. While gyri and sulci had an almost normal US appearance, the periventricular gray matter featured prominently with increased echogenicity. In contrast another CD patient with a more protracted course had ventricular enlargement when examined by US at 5 and 9 months but no alteration in white matter echogenicity. MRI showed impaired myelinization in all three patients with Canavan disease.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 238 (2000), S. 53-58 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  · Objective: Lea symbols can be used for measuring visual acuity in childhood. Therefore, these symbols might be useful for early detection of amblyopia. We evaluated whether the visual acuity determined with Lea symbols (LS) corresponds to the visual acuity determined with the Landolt-C (LC). · Patients and methods: In 55 strabismic amblyopic volunteers aged 5–59 years, the monocular visual acuity of both eyes was determined using LC and LS. For comparison, the right eye of 20 healthy volunteers was examined. Single optotypes (LC, LS) were used in 55 amblyopes and crowded optotypes (LC17.2, LC2.6, CLS) in 40 amblyopes. The luminance of the test charts was 180–200 cd/m2, with a contrast 〉85%. The refraction of the subjects was corrected beforehand. · Results: In the 40 amblyopic eyes tested under each condition, LS exceeded CLS and LC by about 1 line (dB), LC17.2 by 2 lines and LC2.6 by 3 lines (mean values ± SD: LS 0.62±1.8 dB, CLS 0.46±1.7 dB, LC 0.5±2.0 dB, LC17.2 0.41±2.3 dB, LC2.6 0.29±2.3 dB). The non-amblyopic fellow eyes and healthy eyes showed smaller differences (fellow eyes LS 1.32±1.1 dB, CLS 1.17±1.1 dB, LC 1.15±0.9 dB, LC17.2 1.05±0.9 dB, LC2.6 0.93±1.1 dB; healthy eyes LS 1.74±0.9 dB, CLS 1.58±0.8 dB, LC 1.48±0.6 dB, LC17.2 1.41±0.7 dB, LC2.6 1.32±1.1 dB). In the amblyopic eyes, the reduction of LC was more distinct than the reduction of LS. Fifty-two amblyopes had an amblyopia 〉1 dB of LC, LC17.2 and LC2.6, while 50 had an interocular acuity difference 〉1 dB CLS. · Conclusions: Using Lea symbols, a recognition acuity can be determined and amblyopia can reliably be detected. Due to their design, the Lea symbols are particularly suitable and recommendable for application in young children. However a slight systematic difference between LS and LC has to be considered.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1435-1463
    Keywords: 3,4-Dihydroxyphenylserine ; blood pressure ; orthostatic hypotension ; autonomic failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Treatment with L-threo-3,4-dihydroxyphenylserine (L-threo-dops), a synthetic precursor of norepinephrine, significantly increased upright blood pressure in patients with multiple system atrophy but had no effect on the upright blood pressure of patients with pure autonomic failure. These results suggest that the site of action of L-threo-dops is central and that its pressor effect requires intact peripheral sympathetic neurons.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The cross sections of neutrino and antineutrino quasielastic reactions $$vn \to \mu ^ - p,\bar vp \to \mu ^ + n,\bar vp \to \mu ^ + \Lambda$$ were studied in the neutrino energy range between 3 and 30 GeV. In comparison withV-A theory axial mass parameters ofM A =(1.06±0.05±0.14) GeV/c2 from neutrino andM A =(0.71±0.10±0.20) GeV/c2 from antineutrino data were found. The total cross-section for the hyperon production process can be described byM A =1.0 GeV/c2.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Der Ophthalmologe 97 (2000), S. 629-632 
    ISSN: 1433-0423
    Keywords: Schlüsselwörter Videookulographie ; Dreidimensionale Positionsbestimmung ; Gegenrollung ; Interokuläre Differenzbildung ; Irisüberlagerung ; Keywords Object squint measurement ; Iris overlay procedure ; Interocular difference ; Three-dimensional video-oculography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Background. It has long been a goal to develop a means to measure squint angles in three dimensions simultaneously. A three-dimensional binocular method is naturally needed especially with surgical procedures that affect three dimensions of ocular motility. Methods. Special modifications of a videographic method provide simultaneous online data on the three-dimensional position of the eyes. The interocular difference is equal to the amount of squint, depending on the direction of gaze, head-tilt/direction of gravity, and convergence. Results. The method introduced provides three-dimensional and binocular documentation of ocular movements. This could lead to improve pre- and postsurgical examination, especially of rotational disturbances, and it could also offer an objective means for comparing the results of various surgical procedures.
    Notes: Zusammenfassung Hintergrund. Die dreidimensionale Videookulographie wird für den strabologischen Bereich modifiziert und als binokulare Methode vorgestellt. Methode/Ergebnisse. Durch die Videoanalyse eines Pupullenbildes kann die horizontale und vertikale Position des Auges bestimmt werden. Rotatorische Bewegungen um die Blicklinie werden mit einem speziellen Überlagerungsverfahren von Irismerkmalen gemessen. Neue Prozessoren ermöglichen eine alternierende Positionsbestimmung mit 25 Hz und ebenso schneller Berechnung der interokulären Positionsdifferenz. Das Bezugssystem in Form einer Art Taucherbrille mit Videokameras ist an den Kopf des Probanden gebunden. Semitransparente Spiegel erlauben u. a. 9 Blickpositionen analog zur Tangententafel. Die freie Beweglichkeit des Kopfes dient zur Messung von Innenohreinflüssen bei okulärer Gegenrollung. Schlussfolgerung. Die vorgestellte Methode ermöglicht die objektive, simultane Untersuchung beider Augen in 3 Dimensionen in Echtzeit und mit Angabe der Schielwinkel in den 3 Dimensionen.
    Type of Medium: Electronic Resource
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