Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    TWO FORMS OF ALANINE AMINOTRANSFERASE IN RAT BRAIN DURING ONTOGENY (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 32 (1979), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Alanine aminotransferase activity in subcellular fractions of rat brains was investigated during ontogenic development. The activity rose from the prenatal period until adulthood, the highest increase being observed during the period of morphological metabolic and functional maturation of the brain. The rise of the total activity was due predominantly to a rise in the activity of the cytosblic enzyme; the activity of the mitochondrial enzyme did not change markedly during ontogeny. CI-ions and elevated temperature (55°C) inhibited the activity only of the mitochondrial enzyme. Raised temperature stimulated the activity of the cytosolic enzyme while CI-ions did not influence its activity. Our results indicate that 2 alanine aminotransferase isoenzlmes are already present in the rat brain in the prenatal period. It is assumed that the cytosolic enzyme is involved in the regulation of tissue glycol)sis and alanine formation, while the mitochondrial enzyme plays a role in the amino nitrogen transport between mitochondria and cytosol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1979.tb11098.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Über den Einfluß der weiblichen Sexualhormone auf die Capillarpermeabilitat des Auges und der Endometriumgefäße (1953)
    Springer
    Archives of gynecology and obstetrics 184 (1953), S. 86-102 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Untersuchungen über die Beeinflussung der Capillarpermeabilität der Augen- und Endometriumgefäße durch die weiblichen Sexual-hormone ergaben: 1. Unter physiologischen Bedingungen besteht kein Einfluß auf die Augengefäße. 2. Hohe Dosen von Follikelhormon führen zu einer Permeabilitätssteigerung der Augengefäße, höchste Dosen von Follikelhormon und Gelbkörperhormon zu einer Permeabilitätsherabsetzung. 3. Nach Follikel- und Gelbkörperhormon kommt es am Endometrium, das in die Augenvorderkammer von Kaninchen implantiert wurde, zu einer ausgeprägten Permeabilitätserhöhung seiner Gefäße. Follikelhormon und Progesteron potenzieren sich dabei in ihrer Wirkung. 4. Die Wirkungen des Progesterons klingen schneller ab als die des Follikelhormons. Theoretische und klinische Folgerungen, die sich aus den Versuchen ergaben, wurden diskutiert. Außerdem wurde ein Beitrag zur Klärung des sog. „blushing-blunching-phenomen“, von Endometriumtransplantaten in der Augenvorderkammer geleistet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00976119
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Licht- und elektronenmikroskopische sowie cytometrische Untersuchungen an peripheren Nerven beim Morbus Tangier (1979)
    Springer
    Acta neuropathologica 45 (1979), S. 53-59 
    Details
    ISSN: 1432-0533
    Keywords: Tangier disease ; Peripheral nerve ; Electron microscopy ; Cytometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A sural nerve biopsy was performed in a 55-year-old male patient with Tangier disease (familiallipoprotein deficiency). Light-microscopy showed an increase in the endoneural connective tissue and a loss of nerve fibers indicating a chronic peripheral neuropathy. Electron-microscopy revealed an accumulation of lipid droplets within Schwann cells of myelinated and unmyelinated nerve fibers. When compared with age-matched controls the myelinated fiber density was reduced with a relative preponderance of small myelinated fibers. In addition, distributional cytometric studies of nerve vibers in relation to the perineurium and endoneurial capillaries showed: Contrary to 4.6–7.5 μm thick nerve fibers, which accumulated in the center of the nerve fascicle, small (0.5–4.5 μm) and large (7.6–10.0 μm) fibers lay nearby the perineurium. The measured increase in small myelinated nerve fibers around endoneurial capillaries may be explained as a sign of regeneration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691805
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The corpus luteum periodicum in the bitch (1975)
    Springer
    Histochemistry and cell biology 45 (1975), S. 191-201 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The corpus luteum periodicum (c.l.p.) of the bitch was studied using enzyme histochemistry, clinical and biochemical methods. Assessment of variations of the serum progesterone level during different stages of the ovarian cycle and the study of enzymatic activity of the luteal tissue furnished informations on vitality and biosynthetic capacity of luteinizing cells: The period of functional activity of the c.l.p. nearly ceased about day 60 of the cycle (proestrus included) in the animals examined. In the light microscope the neo-synthesis of progesterone in the c.l.-tissue can be made visible by histochemical demonstration of the activity of Delta5-3 beta-hydroxysteroiddehydrogenase (3 beta-HSD) only up to a progesterone level exceeding 6.7 ng/ml plasma. The data obtained contribute to our baseline knowledge of the mechanism involved in the etiology of pseudopregnancylike conditions in the bitch.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00507694
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Alanine formation and alanine aminotransferase activity in the nerve tissue with proliferating macroglia (1976)
    Springer
    Acta neuropathologica 34 (1976), S. 149-155 
    Details
    ISSN: 1432-0533
    Keywords: Alanine ; Alanine aminotransferase activity ; Proliferating macroglia ; Cerebral tissue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the nerve tissue with proliferating macroglia cells were observed a lowered oxygen consumption, an increased aerobic glycolysis and alanine formation and a higher alanine aminotransferase and glutamate dehydrogenase activity than in the control tissue in the homogenates and in the cell sap fraction. The substrate saturation curves, apparent Km and pH optimum values in the tissue with proliferating macroglia and in the control did not differ from one another. The authors assume that a higher alanine amino-transferase activity in the tissue with macroglia proliferation can reflect either a higher synthesis of the enzyme in the altered tissue, or a predominance of glial elements in the altered tissue possessing a higher alanine aminotransferase activity than the nerve cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00684665
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Experimentelle Vitalfärbung des Augenhintergrundes (1954)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 155 (1954), S. 115-166 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00682185
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    The problem of partial endoreduplication (1978)
    Springer
    Human genetics 〈Berlin〉 45 (1978), S. 51-62 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Partial endoreduplication (PE) as defined by Lejeune et al. (1966) has only been found in a few instances. Similar configurations, also called PEs, seem to originate from a different process. A series of 12 PEs is presented in this paper, discovered in metaphases from healthy individuals, and in patients with or without chromosome-breakage syndrome and after treatment with chromosome-breaking agents. Interpretations of the microscopic appearance of each configuration led to the conclusion that there are three different modes of origin for such rare events, one being true partial endoreduplication, the second a partial pseudoendoreduplication, and the third a homologous triradial chromatid translocation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00277573
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Diätetische und medikamentöse Behandlung des Hochdrucks (1954)
    Springer
    Basic research in cardiology 21 (1954), S. 11-40 
    Details
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02122055
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Zur Wirkung des Dicumarols auf die PermeabilitÄt der Capillaren (1951)
    Springer
    Clinical and experimental medicine 118 (1951), S. 131-135 
    Details
    ISSN: 1591-9528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Besprechung und Zusammenfassung Auch wenn berücksichtigt wird, da\ relativ hohe Dicumaroldosen verabreicht wurden und der Capillareffekt nicht in jedem Falle nachzuweisen war, lassen unsere Beobachtungen den Schlu\ zu, da\ schon nach einmaliger Dicumarolgabe wÄhrend einer relativ begrenzten Zeitspanne eine CapillarschÄdigung resultierenkann. Dieser Zeitraum liegt jedenfalls vor der klinisch wirksamen Prothrombinsenkung und deckt sich vor allem, wie wir dies schon früher betonten, keinesfalls mit der Phase niedrigster Prothrombinwerte. Ohne hier nÄher auf die Konsequenzen, die sich daraus für die Dicumaroltherapie bzw. -Prophylaxe ergeben, (z. B. 18, 20) einzugehen, ist jedoch darauf hinzuweisen, da\ eine CapillarschÄdigung als Ursache für eine Blutung nach Dicumarol nur dann ausgeschaltet werden darf, wenn die entsprechende Untersuchung, auf deren negativen Ausfall sich die Ablehnung des causalen Zusammenhanges gründet, in dem Zeitraum, in dem nach dem Gesagten mit einer CapillarschÄdigung zu rechnen ist, durchgeführt wurde.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02049365
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Untersuchung der Capillarpermeablität nach Anwendung von Curare und synthetischen Muskelrelaxantien (1953)
    Springer
    Clinical and experimental medicine 121 (1953), S. 202-208 
    Details
    ISSN: 1591-9528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung An Kaninchen wurde laufend der Austritt einer i.v. injizierten 10%igen Na-Fluoreszeinlösung in das Kammerwasser mit Hilfe einer modifizierten Gullstandschen Spaltlampe als Test der Capillarpermeabilität kontrolliert. Nach i.v. Gabe von Curare, Flaxedil und Curaroid war die Capillardurchlässigkeit gesteigert, am ausgeprägtesten durch Curare, am wenigsten durch Curaroid. Wir erklärten diese Tatsache durch das auch von anderer Seite mitgeteilte Freiwerden von Histamin. Die permeabilitätserhöhende Wirkung des Histamins ist allgemein anerkannt und konnte von anderen Autoren auch durch eine gesteigerte Fluoreszeinausscheidung in das Kammerwasser nachgewiesen werden, was uns selbst allerdings bei i.v. Gaben bis zu 1 mg/kg bei Kaninchen nicht gelang. Ein indirekter Beweis für unsere Annahme der Histaminmobilisation durch Curare war jedoch die überwiegende Normalisierung des durch die Muskelrelaxantien erhöhten Farbstoffaustritts nach Prämedikation von Antistin. In der klinischen Praxis verwenden wir deshalb seit über 2 Jahren Antihistaminika zur Prophylaxe des Operationsschocks, der Ödembildung und des Bronchospasmus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02048249
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...