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  • 1
    Electronic Resource
    Electronic Resource
    Soluble L -selectin plasma concentrations in infants undergoing heart surgery: no association with capillary leak syndrome or need for respiratory support (1998)
    Springer
    Intensive care medicine 24 (1998), S. 1093-1098 
    Details
    ISSN: 1432-1238
    Keywords: Key words Infant ; Congenital heart disease ; ARDS ; Capillary leak ; Soluble l-selectin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: In critical care patients at risk of developing the acute respiratory distress syndrome (ARDS), low soluble l-selectin (sCD62L) plasma concentrations have been shown to be associated with progression to ARDS and prolonged subsequent mechanical ventilation. This study aimed to determine the usefulness of sCD62L plasma concentrations to identify infants undergoing cardiovascular surgery who are at risk for postoperative pulmonary dysfunction and capillary leaks. Design: Serial measurements of sCD62L plasma concentrations in a cohort of infants with congenital heart disease before, during, and after surgery for 4 consecutive days. Setting and patients: Infants aged 3–337 days undergoing cardiovascular surgery with (N = 27) or without (N = 12) cardiopulmonary bypass in a tertiary care center. Results: sCD62L concentrations before surgery showed a strong correlation with the infant's age (r = 0.77, p 〈 0.001). During surgery, sCD62L levels dropped from 9.0 ± 0.7 to 5.6 ± 0.4 nmol/l (mean ± SEM; p 〈 0.001). The minimum sCD62L concentration during and after surgery did not differ between infants operated upon with or without cardiopulmonary bypass (p 〉 0.1) or in infants who did (N = 10) or did not (N = 29) develop capillary leak syndrome. Whereas capillary leak syndrome was associated with prolonged mechanical ventilation (p 〈 0.01), there was no relationship between sCD62L concentrations at baseline or at any time thereafter and number of hours on the ventilator (p 〉 0.1). Conclusion: sCD62L concentrations before or after surgery are not apt to identify infants at increased risk of prolonged mechanical ventilation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050722
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  • 2
    Electronic Resource
    Electronic Resource
    Acute hemodynamic effects of post cardiotomy peritoneal dialysis in neonates and infants (2000)
    Springer
    Intensive care medicine 26 (2000), S. 101-104 
    Details
    ISSN: 1432-1238
    Keywords: Key words Peritoneal dialysis ; Acute renal failure ; Congenital heart disease ; Cardiac output measurements ; Open chest
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Evaluation of the acute hemodynamic changes during peritoneal dialysis in patients with low cardiac output syndrome and acute renal failure after open heart surgery.¶Patients: Three newborns and three infants after corrective surgery of congenital heart disease with post cardiotomy dialysis. Five of these had an open thorax during dialysis.¶Methods: Cardiac output measurements using the thermodilution technique on two consecutive days at four different times during the peritoneal dialysis cycle.¶Results: We did not find a deterioration of the cardiac index or systemic vascular resistance measured over two cycles in each of the six patients. Pulmonary artery pressure rose slightly after instillation of the dialysate solution in all patients. Changes in central venous pressure and left atrial pressure were not clinically meaningful. In all patients fluid removal by peritoneal dialysis was effective. All five surviving patients recovered renal function.¶Conclusions: Peritoneal dialysis can be performed in newborns and infants following cardiac surgery without causing acute hemodynamic imbalances. An open chest may have a significant impact on hemodynamic stability during peritoneal dialysis by blunting any possible negative alterations of increased intraabdominal pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050020
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Acute ventilatory restriction in children after weaning off inhaled nitric oxide: relation to rebound pulmonary hypertension (1999)
    Springer
    Intensive care medicine 25 (1999), S. 76-80 
    Details
    ISSN: 1432-1238
    Keywords: Key words Nitric oxide ; Rebound ; Pulmonary hypertension ; Dynamic respiratory system compliance ; Interaction ; Congenital heart disease compliance ; Interaction ; Congenital heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To assess the interaction between pulmonary hemodynamics and respiratory mechanics during acute pulmonary hypertension. Patients: Ventilated and paralysed children treated with inhaled nitric oxide because of post-operative pulmonary hypertension. Interventions: Weaning of inhaled nitric oxide. Measurements: Air flow and airway pressure, calculation of dynamic respiratory system compliance and respiratory system resistance for each breath by multiple linear regression. Results: In four patients, increases in pulmonary arterial pressure from 26.1 to 56.7 mmg (p 〈 0.001) during weaning off nitric oxide were associated with decreases in tidal volume (from 9.7 → 8.2 ml/kg, p 〈 0.01) and reductions in dynamic respiratory system compliance (from 0.52 → 0.34 cmH20/ml/kg, p 〈 0.001), while respiratory system resistance was unchanged. Conclusions: Impaired ventilation during acute pulmonary hypertension is predominantly related to a reduction in respiratory system compliance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050790
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Fehlerhafter Abgang der rechten Koronararterie aus der A. pulmonalis bei einem asymptomatischen Schulkind (1997)
    Springer
    Monatsschrift Kinderheilkunde 145 (1997), S. 226-229 
    Details
    ISSN: 1433-0474
    Keywords: Schlüsselwörter Anomaler Abgang der rechten Koronararterie ; Bland-White-Garland-Syndrom ; Angeborene Herzfehler ; Key words Anomalous origin of the right coronary artery ; Bland-White-Garland-Syndrome ; Congenital heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Anomalous origin of the right coronary artery from the pulmonary trunk is rare, however, it is of considerable clinical significance. Discussion: We report of the findings in an asymptomatic child with anomalous origin of the right coronary artery from the pulmonary trunk and shortly review this entity.
    Notes: Zusammenfassung Der fehlerhafte Abgang der rechten Koronararterie aus der Pulmonalarterie ist selten, jedoch von erheblicher klinischer Relevanz. Diskussion: Wir berichten über die Befunde eines asymptomatischen Schulkinds mit diesem Krankheitsbild und geben einen Überblick über diese Fehlbildung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001120050118
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    Paper (German National Licenses)
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