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  • Hepatic lipase  (2)
  • Isolierte Fettzellen  (2)
  • Acute leukemia  (1)
  • Adherence  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Successful treatment of recurrent hepatic Candida infection with fluconazole after chemotherapy for acute leukemia: a case report (1992)
    Springer
    Journal of molecular medicine 70 (1992), S. 55-58 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Hepatic candidiasis ; Fluconazole ; Chemotherapy ; Acute leukemia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Hepatic candidiasis represents an increasingly difficult problem in immunocompromised patients. It has been recognized as a variant of disseminated candidiasis after a period of neutropenia. Establishment of diagnosis is difficult since liver biopsy as well as culture may be negative, in spite of the presence of fungus. Hepatic lesions are generally not detectable by ultrasound examination or computed tomography until the neutrophil count has returned to normal. The aim of this case report is to describe the problems related to the diagnosis and treatment of hepatic candidiasis following chemotherapy for acute leukemia. The report also provides further evidence that fluconazole, a new broad-spectrum antifungal drug, can be safely and effectively used for the long-term treatment of deep-seated hepatic candidiasis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00422941
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  • 2
    Digitale Medien
    Digitale Medien
    Lipoproteins, HDL-apolipoproteins, activities of hepatic lipase and lecithin-cholesterol acyltransferase in the plasma of patients with post-alcoholic end-stage liver cirrhosis (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 929-931 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Liver cirrhosis ; Lipoproteins ; LCAT ; Hepatic lipase
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary 12 patients with unequivocal post-alcoholic end-stage liver cirrhosis were compared with 12 healthy controls with regard to the plasma concentrations of lipids, lipoproteins (by rate zonal ultra-centrifugation) and apolipoproteins of high-density-lipoproteins (HDL) (by disc electrophoresis), as well as to the activities of lecithin-cholesterol acyltransferase (LCAT) in plasma and of hepatic lipase (HL) in post-heparin plasma. The cirrhotic group showed the following differences (all significant at thep〈0.01 level) from the control group: Total cholesterol, HDL-cholesterol, very-low-density-lipoproteins (VLDL), HDL, and HL were decreased. Intermediate-density-lipoproteins (IDL) were not detectable in the cirrhotic group. Low-density-lipoproteins (LDL) did not differ significantly from controls. However, LDL from cirrhotic patients contained more triglycerides but less esterified and free cholesterol (allp〈0.01). The percentage apolipoprotein composition of HDL did not differ significantly between controls and cirrhotics. Surprisingly, LCAT acivity in plasma as well as the ratios between esterified and free cholesterol in plasma, LDL, and HDL were nearly identical in both groups. It seems likely that LCAT activity decreases only in the states of acute or subacute liver injury or of biliary obstruction. Severe chronic liver damage as in our cases of end-stage liver cirrhosis without any signs of acute liver injury exhibits apparently no defect in cholesterol esterification.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01537534
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  • 3
    Digitale Medien
    Digitale Medien
    Stimulating effect of intermediate-density lipoproteins (IDL) from hyperlipemic plasma on hepatic lipase (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 530-533 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Hepatic lipase ; Lipoproteins ; Hyperlipemia ; Intermediate-density lipoproteins (IDL)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The main lipoprotein density classes, namely very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), high-density lipoproteins2 (HDL2) and HDL3 were investigated with respect to their influence on hepatic lipase (HTGL) activity in vitro. Lipoproteins from pooled normal plasma (NP) and from pooled hyperlipemic plasma (HP) were prepared by means of sequential ultracentrifugation. Hepatic lipase was determined radioenzymatically after preincubation with protamine sulfate. It could be demonstrated that IDL from HP were able to stimulate HTGL activity by approximately 100% above the baseline value. HDL3 from both NP and HP revealed an inhibiting effect on HTGL activity. VLDL, LDL, and HDL2 exhibited no significant effect on HTGL activity. It is speculated that HTGL could possibly represent a second pathophysiological pathway for the catabolism of IDL in hyperlipemia but this presumption is supported by only a few investigations in vivo.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01713062
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  • 4
    Digitale Medien
    Digitale Medien
    Priming of normal human neutrophils by tachykinins: tuftsin-like inhibition of in vitro chemotaxis stimulated by formylpeptide or interleukin-8
    Amsterdam : Elsevier
    Regulatory Peptides 36 (1991), S. 359-368 
    Details
    ISSN: 0167-0115
    Schlagwort(e): Adherence ; Inflammation ; Neuroimmunomodulation ; Phagocyte ; Sensory neuropeptide
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-0115(91)90069-S
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  • 5
    Digitale Medien
    Digitale Medien
    Effect of general and local anaesthesia on basal and noradrenaline-stimulated lipolysis in isolated human subcutaneous fat cells (1974)
    Springer
    Research in experimental medicine 163 (1974), S. 335-339 
    Details
    ISSN: 1433-8580
    Schlagwort(e): General anaesthesia ; Isolated fat cells ; Lipolysis ; Local anaesthesia ; Procain hydrochloride ; Allgemeinnarkose ; Isolierte Fettzellen ; Lipolyse ; Lokalanaesthesie ; Procainhydrochlorid
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung In isolierten menschlichen Fettzellen des abdominellen Subcutanfettgewebes wurde der Effekt einer Allgemeinnarkose im Vergleich zur Lokalanaesthesie auf die basale und Noradrenalin-induzierte Lipolyse untersucht. Es konnte gezeigt werden, daß Procainhydrochloridin vitro stark antilipolytisch wirksam war. Präinkubation des Fettgewebes mit Procainhydrochlorid hatte keinen Einfluß auf die lipolytische Aktivität in den isolierten Fettzellen. Zwischen Allgemeinnarkose und Lokalanaesthesie bestand hinsichtlich ihres Einflusses auf die Lipolyse in isolierten Fettzellen kein signifikanter Unterschied.
    Notizen: Summary In isolated human fat cells of the subcutaneous abdominal region the effect of general anaesthesia as compared to local anaesthesia on basal and noradrenaline-stimulated lipolysis has been investigated. It could be shown that procain hydrochloride exerted a marked antilipolytic action when addedin vitro. Preincubation of the whole adipose tissue with procain hydrochloride prior to the isolation procedure did not alter the lipolytic activity in the fat cells. There was no significant difference in lipolysis between fat cells obtained from patients under general anaesthesia and cells from individuals under local anaesthesia with procain hydrochloride.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01851520
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  • 6
    Digitale Medien
    Digitale Medien
    Basale und Noradrenalin-(NA-)induzierte Lipolyse in isolierten Fettzellen des Menschen bei isocalorischer und hypocalorischer Diät (1973)
    Springer
    Journal of molecular medicine 51 (1973), S. 735-737 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Isolated fat cells ; lipolysis ; starvation ; noradrenalin ; Isolierte Fettzellen ; Lipolyse ; Hunger ; Noradrenalin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung An isolierten Fettzellen des abdominellen Subcutanfettgewebes übergewichtiger Patienten unter isocalorischer und hypocalorischer Diät wurde die basale Lipolyse und deren Stimulierbarkeit durch Noradrenalin untersucht. Es konnte gezeigt werden, daß unter hypocalorischen Ernährungsbedingungen die basale Lipolyse auf das 4,5fache der Norm erhöht ist, und zum Unterschied von der Lipolyse unter isocalorischer Kost durch Noradrenalin nicht mehr signifikant gesteigert werden kann. Es ist anzunehmen, daß es im Hunger zu einer maximalen Aktivität der hormonsensitiven Lipase kommt, die durch maximale Dosen von Noradrenalin nicht mehr weiter stimuliert werden kann.
    Notizen: Summary In isolated human fat cells of the subcutaneous abdominal region the effect of noradrenalin on lipolysis was tested under isocaloric and hypealoric diet. It could be demonstrated that with hypocaloric diet, the basal lipolysis increased 4,5-fold and could not be further stimulated by maximal doses of noradrenalin. It is suggested that starvation results in a maximal activity of the hormone-sensitive lipase, which it is impossible to further increase by noradrenalin.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01468366
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