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  • 1
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 186 (1992), S. 1362-1367 
    ISSN: 0006-291X
    Schlagwort(e): [abr] BMP; bone morphogenetic protein ; [abr] BSA; bovine serum albumin ; [abr] CIA; collageninduced arthritis ; [abr] CII; type II collagen ; [abr] HBF; heterotopic bone formation ; [abr] IL-1; interleukin-1 ; [abr] PBS; phosphate-buffered saline ; [abr] RA; rheumatoid arthritis
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 186 (1992), S. 1362-1367 
    ISSN: 0006-291X
    Schlagwort(e): [abr] BMP; bone morphogenetic protein ; [abr] BSA; bovine serum albumin ; [abr] CIA; collageninduced arthritis ; [abr] CII; type II collagen ; [abr] HBF; heterotopic bone formation ; [abr] IL-1; interleukin-1 ; [abr] PBS; phosphate-buffered saline ; [abr] RA; rheumatoid arthritis
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    ISSN: 1432-0568
    Schlagwort(e): Key words Frontal cortex ; Visual cortex ; Primate ; BDNF ; NT4/5
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Distribution and morphological changes of cells containing the signal transducing neurotrophin receptor, full-length Trk B (fl-Trk B), were investigated in the prefrontal cortex (area FD) and the primary visual cortex (area OC) of the macaque monkey between embryonic day 140 and the adult stage. In area FD at the adult stage, fl-Trk B immunoreactivity was mainly observed in the pyramidal cells in layers II/III, V and VI. Small numbers of granule cells in layer IV were immunopositive. Bipolar and multipolar cells in layer II were rarely immunoreactive. At embryonic day 140, the number of fl-Trk B immunoreactive pyramidal cell was high, and gradually decreased until the adult stage. In layer IV, the number of fl-Trk B-ir cells was also high at embryonic day 140, and decreased remarkably from postnatal day 7 to the adult stage. On the other hand, in area OC at the adult stage, cells in layers II/III, IV, V and VI were fl-Trk B immunopositive. From embryonic day 140 until adulthood, the cells in layer IVc were fl-Trk B immunoreactive. The strongest fl-Trk B immunoreactivity in areas FD and OC occurred at postnatal month 6, coinciding with the time of the synapse overproduction. These findings suggest that ligands of fl-Trk B, such as BDNF and NT4/5 may be involved in the development and maintenance of the monkey cerebral cortices.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 74 (1989), S. 249-255 
    ISSN: 1432-1106
    Schlagwort(e): Cholecystokinin-8 ; Glutamic acid de-carboxylase ; Cerebral cortex ; Primate ; Ontogeny
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Concentration of cholecystokinin-8 and the activity of glutamic acid decarboxylase were determined in the various cerebral cortical subdivisions of Japanese monkey (Macaca fuscata fuscata) at three different ages (embryonic 4 months, full-term and adult). The CCK-8 immunoreactive material extracted with 90% methanol from the cerebral cortex of the adult and foetal monkey were shown to be identical with synthetic cholecystokinin-8 by the criterion of co-elution on gel filtration chromatography (Sephadex G-50). The peptide concentration increased dramatically by about 30–80 fold (in terms of protein) and 17–28 fold (in terms of wet weight) between embryonic 4-month-old and full-term monkeys, while the level decreased 1/6–1/16 (protein) and 1/4–1/10 (wet weight) between full-term and adult monkeys. In adults, the highest levels of the peptide was observed in the association cortex, orbital prefrontal cortex and posterior parietal cortex. Glutamic acid decarboxylase activity, on the other hand, gradually increased about 4–10 fold (protein) between embryonic 4-month-old and adult animals and there was little variation in the increase rate among the cerebral subdivisions. In contrast to cholecystokinin-8, no reduction in the enzyme activity occurred between full-term and adult animals. The high level of cholecystokinin-8 in the embryonic period suggests that the peptide may participate in the regulation of the development of primate cerebral cortex.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 31 (1993), S. 1-11 
    ISSN: 0887-624X
    Schlagwort(e): chemical amplification ; photoresist ; poly(p-hydroxystyrene) ; photocrosslinking ; carbocationic ; radiation-sensitive ; crosslinker ; triarylsulfonium salt ; thin-film chemistry ; UV ; E-beam ; x-ray ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: New resist systems based on acid-catalyzed, electrophilic aromatic substitution are described. These new resists show high sensitivity to deep UV and E-beam radiation with values approaching 2 mJ/cm2 and 2 μC/cm2, respectively. The resists are based on a three component system consisting of poly(4-hydroxystyrene), a polyfunctional, low molecular weight, latent electrophile, and a photoactive onium salt used as an acid generator. Irradiation of the resist film produces a latent image of acid dispersed in the matrix. During the postbaking step the photo-generated acid reacts with the latent polyfunctional electrophile and releases a reactive carbocationic intermediate with concomitant liberation of acetic acid. The carbocationic intermediate then reacts with neighboring phenolic moieties in a crosslinking reaction. The substitution reaction liberates a proton, making the process catalytic in nature, thus incorporating the concept of chemical amplification. These highly sensitive materials can be used as nonswelling negative multipurpose resists that function in deep-UV, x-ray or E-beam modes. © 1993 John Wiley & Sons, Inc.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 44 (1992), S. 127-134 
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: A new carbon fiber was prepared from the lignin (steam-exploded lignin), which was isolated from steam-exploded birch wood (Betula platyphylla). The lignin was modified to melt thermally on hydrogenolysis. The chloroform soluble and carbon disulfide insoluble fraction (HL) of the reaction products was heated at 300-350°C for 30 min, giving a molten viscous material (HHL). The HHL had a softening point of 110°C and melted at over 145°C to form viscous liquid. When HHL was subjected to a spinning test, according to a conventional fusion spinning method at a speed over 100 m/min, a fine filament could be continuously formed through a pinhole (diameter: 0.3 mm). After the filaments were heated in air at 1-2°C/min up to 210°C, by which time the filament was converted to have an infusible property, the filaments were carbonized by heating from a room temperature to 1000°C at a heating rate of 5°C/min in a stream of nitrogen. The typical properties of the lignin based carbon fiber were as follows: Fiber diameter = 7.6 ± 2.7μ Elongation = 1.63 ± 0.29% Tensile strength = 660 ± 230 MPa; Modulus of elasticity = 40.7 ± 6.3 GPa. The chemical structure of the precursor was remarkably changed from that of the original lignin, indicating the elimination of aliphatic functional groups implied originally in the starting material.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 48 (1993), S. 1485-1491 
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: A lignin-pitch for carbon fiber was prepared in a high yield from exploded lignin on phenolysis followed by heat treatment under a vacuum. The lignin-pitch had an excellent spinnability in the melt state to form a fine filament. The green fibers were easily made infusible when heated in air at a relatively high heating rate (15-60°C/h). The lignin-based carbon fiber was produced in 43.7% of yield based on a starting material. The tensile strength was more than 400 MPa, indicating that the lignin-based carbon fiber is classified into a general purpose grade. © 1993 John Wiley & Sons, Inc.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 27 (1993), S. 729-734 
    ISSN: 0021-9304
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin , Technik allgemein
    Notizen: Zirconia has received special attention, mainly because of its high strength and toughness. However, there is some controversy about the time-dependent deterioration of its mechanical properties. To examine the change in mechanical properties of zirconia ceramics in vivo and in vitro, tetragonal zirconia polycrystal pieces were introduced into the medullary cavity of the tibia in Japanese rabbits and animals were sacrificed after 2, 4 and 6 weeks and 6, 12, and 30 mo, respectively. Alumina ceramic and hydroxyapatite (HAP) pieces were used as controls to investigate the differences in biocompatibility. Zirconia showed a bending strength of over 1000 MPa initially, and little time-dependent change in strength was found in both in vivo environments. x-Ray analysis showed little change in the transformation rate, i.e., less than 5 mol % in vivo and in vitro over a period of 3 years. To estimate time-dependent changes in zirconia over a longer period, zirconia pieces were placed in 95°C saline solution for over 3 years and their mechanical properties examined at chosen intervals. No serious decrease of bending strength was found over the 3-year period under these conditions. It is concluded that zirconia can be used clinically because it retains a bending strength of over 700 MPa under any experimental conditions for over 3 years. © 1993 John Wiley & Sons, Inc.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    ISSN: 0142-2421
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Physik
    Notizen: Compositions and elemental distributions of anodic films formed on aluminium in aqueous borate electrolytes have been investigated by Rutherford backscattering spectroscopy (RBS) and associated nuclear reaction methods, together with controlled crystallization of film sections in the transmission electron microscope (TEM). Films were found to consist principally of Al2O3; the outer regions of the films were contaminated with boron and, for all cases studied, the inner regions were boron-free. In the absence of film dissolution the contaminated region represented approximately 40% of the film thickness, and this proportion did not vary significantly with changes in current density of film formation. The outer region contained about 1.5 wt% boron, probably as B2O3, and the densities of the inner and outer regions were similar to an accuracy of about 10%.
    Zusätzliches Material: 10 Ill.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 14 (1989), S. 619-622 
    ISSN: 0142-2421
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Physik
    Notizen: The incorporation and amphoteric behavior of Si impurities in Si-doped (100) oriented molecular beam epitaxial (MBE) GaAs layers grown under different As4/Ga flux ratios but with a fixed Si flux have been studied using Hall effect measurements, photothermal ionization spectroscopy and photoluminescence. The Si donor concentration increases substantially with increasing As4/Ga flux ratio, while the Si acceptor concentration remains less than ∼ 1013 cm-3, regardless of the variation of As4/Ga flux ratio. The observed increase of carrier concentration with increasing V/III ratio is not due to a change of site preference of Si impurities from Ga to As sublattice sites as previously supposed, but is due to the increase in incorporation of Si donor. This result can be explained by the kinetic effects associated with surface reaction processes involved in Si impurity incorporation. From these results it is clear that the sticking coefficient of Si is less than unity, and varies with the growth conditions.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
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