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  • 1
    facet.materialart.
    Unbekannt
    Publikationsdatum: 2022-03-14
    Beschreibung: In the recent years, a couple of quite successful large neighborhood search heuristics for mixed integer programs has been published. Up to our knowledge, all of them are improvement heuristics. We present a new start heuristic for general MIPs working in the spirit of large neighborhood search. It constructs a sub-MIP which represents the space of all feasible roundings of some fractional point - normally the optimum of the LP-relaxation of the original MIP. Thereby, one is able to determine whether a point can be rounded to a feasible solution and which is the best possible rounding. Furthermore, a slightly modified version of RENS proves to be a well-performing heuristic inside the branch-cut-and-price-framework SCIP.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 2
    Publikationsdatum: 2020-08-05
    Beschreibung: We consider polytopes associated with cardinality constrained path and cycle problems defined on a directed or undirected graph. We present integer characterizations of these polytopes by facet defining linear inequalities for which the separation problem can be solved in polynomial time. Moreover, we give further facet defining inequalities, in particular those that are specific to odd/even paths and cycles.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 3
    Publikationsdatum: 2020-08-05
    Beschreibung: Algorithmic control of elevator systems has been studied for a long time. More recently, a new paradigm for elevator control has emerged. In destination call systems, the passenger specifies not only the direction of his ride, but the destination floor. Such a destination call system is very interesting from an optimization point of view, since more information is available earlier, which should allow improved planning. However, the real-world destination call system envisioned by our industry partner requires that each destination call (i.e. passenger) is assigned to a serving elevator immediately. This early assignment restricts the potential gained from the destination information. Another aspect is that there is no way to specify the destination floor in the cabin. Therefore, the elevator has to stop on every destination floor of an assigned call, although the passenger may not have boarded the cabin, e.g. due to insufficient capacity. In this paper we introduce a new destination call control algorithm suited to this setting. Since the control algorithm for an entire elevator group has to run on embedded microprocessors, computing resources are very scarce. Since exact optimization is not feasible on such hardware, the algorithm is an insertion heuristic using a non-trivial data structure to maintain a set of tours. To assess the performance of our algorithm, we compare it to similar and more powerful algorithms by simulation. We also compare to algorithms for a conventional system and with a more idealized destination call system. This gives an indication of the relative potentials of these systems. In particular, we assess how the above real-world restrictions influence performance. The algorithm introduced has been implemented by our industry partner for real-world use.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 4
    facet.materialart.
    Unbekannt
    Publikationsdatum: 2020-08-05
    Beschreibung: This thesis is concerned with dimensioning and routing optimization problems for communication networks that employ a shortest path routing protocol such as OSPF, IS-IS, or RIP. These protocols are widely used in the Internet. With these routing protocols, all end-to-end data streams are routed along shortest paths with respect to a metric of link lengths. The network administrator can configure the routing only by modifying this metric. In this thesis we consider the unsplittable shortest path routing variant, where each communication demand must be sent unsplit through the network. This requires that all shortest paths are uniquely determined. The major difficulties in planning such networks are that the routing can be controlled only indirectly via the routing metric and that all routing paths depend on the same routing metric. This leads to rather complicated and subtle interdependencies among the paths that comprise a valid routing. In contrast to most other routing schemes, the paths for different communication demands cannot be configured independent of each other. Part I of the thesis is dedicated to the relation between path sets and routing metrics and to the combinatorial properties of those path sets that comprise a valid unsplittable shortest path routing. Besides reviewing known approaches to find a compatible metric for a given path set (or to prove that none exists) and discussing some properties of valid path sets, we show that the problem of finding a compatible metric with integer lengths as small as possible and the problem of finding a smallest possible conflict in the given path set are both NP-hard to approximate within a constant factor. In Part II of the thesis we discuss the relation between unsplittable shortest path routing and several other routing schemes and we analyze the computational complexity of three basic unsplittable shortest path routing problems. We show that the lowest congestion that can be obtained with unsplittable shortest path routing may significantly exceed that achievable with other routing paradigms and we prove several non-approximability results for unsplittable shortest path routing problems that are stronger than those for the corresponding unsplittable flow problems. In addition, we derive various polynomial time approximation algorithms for general and special cases of these problems. In Part III of the thesis we finally develop an integer linear programming approach to solve these and more realistic unsplittable shortest path routing problems to optimality. We present alternative formulations for these problems, discuss their strength and computational complexity, and show how to derive strong valid inequalities. Eventually, we describe our implementation of this solution approach and report on the numerical results obtained for real-world problems that came up in the planning the German National Research and Education Networks G-WiN and X-WiN and for several benchmark instances.
    Beschreibung: Die Arbeit befasst sich mit der Kapazitäts- und Routenplanung für Kommunikationsnetze, die ein kürzeste-Wege Routingprotokoll verwenden. Diese Art von Protokollen ist im Internet weit verbreitet. Bei diesen Routingverfahren wird für jede Verbindung im Netz ein Längenwert festgelegt, diese Längen formen die sogenannte Routingmetrik. Die Routingwege der Kommunikationsbedarfe sind dann die jeweiligen kürzesten Wege bezüglich dieser Metrik. Bei der in der Arbeit untersuchten Variante dieser Routingprotokolle wird zusätzlich verlangt, dass es je Kommunikationsbedarf genau einen eindeutigen kürzesten Weg gibt. Die Schwierigkeit bei der Planung solcher Netze besteht darin, dass sich die Routingwege einerseits nur indirekt über die Routingmetrik beeinflussen lassen, andererseits aber alle Routingwege von der gleichen Metrik abhängen. Dadurch können die Wege verschiedener Kommunikationsanforderungen nicht wie bei anderen Routingverfahren unabhängig voneinander gewählt werden. Im erstem Teil der Arbeit werden der Zusammenhang zwischen gegebenen Wegesystemen und kompatiblen Routingmetriken sowie die Beziehungen der Wege eines zulässigen eindeutige-kürzeste-Wege-Routings untereinander untersucht. Dabei wird unter Anderem gezeigt, dass es NP-schwer ist, eine kompatible Metrik mit kleinstmöglichen Routinglängen zu einem gegebenen Wegesystem zu finden. Es wird auch bewiesen, dass das Finden eines kleinstmöglichen Konfliktes in einem gegebenen Wegesystem, zu dem keine kompatible Metrik existiert, NP-schwer ist. Im zweiten Teil der Arbeit wird die Approximierbarkeit von drei grundlegenden Netz- und Routenplanungsproblemen mit eindeutige-kürzeste-Wege-Routing untersucht. Für diese Probleme werden stärkere Nichtapproximierbarkeitsresultate als für die entsprechenden Einwege-Routing Probleme bewiesen und es werden verschiedene polynomiale Approximationsverfahren für allgemeine und Spezialfälle entworfen. Ausserdem wird die Beziehung zwischen eindeutige-kürzeste-Wege-Routing und anderen Routingverfahren diskutiert. Im dritten und letzten Teil der Arbeit wird ein (gemischt-) ganzzahliger Lösungsansatz für Planungsprobleme mit eindeutige-kürzeste-Wege-Routing vorgestellt. Für die im zweiten Teil diskutierten grundlegenden Netz- und Routenplanungsprobleme werden verschiedene (gemischt-) ganzzahlige lineare Modelle vorgestellt und es wird deren Lösbarkeit und die Stärke ihrer LP Relaxierungen untersucht. Es wird auch gezeigt, wie sich starke gültig Ungleichungen aus den in diesen Modellen enthalten Substrukturen ableiten lassen. Schlielich werden am Ende der Arbeit die Software-Implementierung dieses Lösungsverfahrens für eine praxisrelevante Verallgemeinerung der Planungsprobleme sowie die damit erzielten numerischen Ergebnisse vorgestellt und diskutiert.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 5
    facet.materialart.
    Unbekannt
    Publikationsdatum: 2021-08-05
    Beschreibung: This thesis introduces the novel paradigm of constraint integer programming (CIP), which integrates constraint programming (CP) and mixed integer programming (MIP) modeling and solving techniques. It is supplemented by the software SCIP, which is a solver and framework for constraint integer programming that also features SAT solving techniques. SCIP is freely available in source code for academic and non-commercial purposes. Our constraint integer programming approach is a generalization of MIP that allows for the inclusion of arbitrary constraints, as long as they turn into linear constraints on the continuous variables after all integer variables have been fixed. The constraints, may they be linear or more complex, are treated by any combination of CP and MIP techniques: the propagation of the domains by constraint specific algorithms, the generation of a linear relaxation and its solving by LP methods, and the strengthening of the LP by cutting plane separation. The current version of SCIP comes with all of the necessary components to solve mixed integer programs. In the thesis, we cover most of these ingredients and present extensive computational results to compare different variants for the individual building blocks of a MIP solver. We focus on the algorithms and their impact on the overall performance of the solver. In addition to mixed integer programming, the thesis deals with chip design verification, which is an important topic of electronic design automation. Chip manufacturers have to make sure that the logic design of a circuit conforms to the specification of the chip. Otherwise, the chip would show an erroneous behavior that may cause failures in the device where it is employed. An important subproblem of chip design verification is the property checking problem, which is to verify whether a circuit satisfies a specified property. We show how this problem can be modeled as constraint integer program and provide a number of problem-specific algorithms that exploit the structure of the individual constraints and the circuit as a whole. Another set of extensive computational benchmarks compares our CIP approach to the current state-of-the-art SAT methodology and documents the success of our method.
    Beschreibung: Diese Arbeit stellt einen integrierten Ansatz aus Constraint Programming (CP) und Gemischt-Ganzzahliger Programmierung (Mixed Integer Programming, MIP) vor, den wir Constraint Integer Programming (CIP) nennen. Sowohl Modellierungs- als auch Lösungstechniken beider Felder fließen in den neuen integrierten Ansatz ein, um die unterschiedlichen Stärken der beiden Gebiete zu kombinieren. Als weiteren Beitrag stellen wir der wissenschaftlichen Gemeinschaft die Software SCIP zur Verfügung, die ein Framework für Constraint Integer Programming darstellt und zusätzlich Techniken des SAT-Lösens beinhaltet. SCIP ist im Source Code für akademische und nicht-kommerzielle Zwecke frei erhältlich. Unser Ansatz des Constraint Integer Programming ist eine Verallgemeinerung von MIP, die zusätzlich die Verwendung beliebiger Constraints erlaubt, solange sich diese durch lineare Bedingungen ausdrücken lassen falls alle ganzzahligen Variablen auf feste Werte eingestellt sind. Die Constraints werden von einer beliebigen Kombination aus CP- und MIP-Techniken behandelt. Dies beinhaltet insbesondere die Domain Propagation, die Relaxierung der Constraints durch lineare Ungleichungen, sowie die Verstärkung der Relaxierung durch dynamisch generierte Schnittebenen. Die derzeitige Version von SCIP enthält alle Komponenten, die für das effiziente Lösen von Gemischt-Ganzzahligen Programmen benötigt werden. Die vorliegende Arbeit liefert eine ausführliche Beschreibung dieser Komponenten und bewertet verschiedene Varianten in Hinblick auf ihren Einfluß auf das Gesamt-Lösungsverhalten anhand von aufwendigen praktischen Experimenten. Dabei wird besonders auf die algorithmischen Aspekte eingegangen. Der zweite Hauptteil der Arbeit befasst sich mit der Chip-Design-Verifikation, die ein wichtiges Thema innerhalb des Fachgebiets der Electronic Design Automation darstellt. Chip-Hersteller müssen sicherstellen, dass der logische Entwurf einer Schaltung der gegebenen Spezifikation entspricht. Andernfalls würde der Chip fehlerhaftes Verhalten aufweisen, dass zu Fehlfunktionen innerhalb des Gerätes führen kann, in dem der Chip verwendet wird. Ein wichtiges Teilproblem in diesem Feld ist das Eigenschafts-Verifikations-Problem, bei dem geprüft wird, ob der gegebene Schaltkreisentwurf eine gewünschte Eigenschaft aufweist. Wir zeigen, wie dieses Problem als Constraint Integer Program modelliert werden kann und geben eine Reihe von problemspezifischen Algorithmen an, die die Struktur der einzelnen Constraints und der Gesamtschaltung ausnutzen. Testrechnungen auf Industrie-Beispielen vergleichen unseren Ansatz mit den bisher verwendeten SAT-Techniken und belegen den Erfolg unserer Methode.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 6
    Publikationsdatum: 2016-06-09
    Beschreibung: In this paper, we investigate the interconversion processes of the major flame retardant -- 1,2,5,6,9,10-hexabromocyclododecane (HBCD) -- by the means of statistical thermodynamics based on classical force-fields. Three ideas will be presented. First, the application of classical hybrid Monte-Carlo simulations for quantum mechanical processes will be justified. Second, the problem of insufficient convergence properties of hybrid Monte-Carlo methods for the generation of low temperature canonical ensembles will be solved by an interpolation approach. Furthermore, it will be shown how free energy differences can be used for a rate matrix computation. The results of our numerical simulations will be compared to experimental results.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 7
    facet.materialart.
    Unbekannt
    Publikationsdatum: 2022-03-14
    Beschreibung: In this paper we give an overview of the heuristics which are integrated into the open source branch-cut-and-price-framework SCIP. We briefly describe the fundamental ideas of different categories of heuristics and present some computational results which demonstrate the impact of heuristics on the overall solving process of SCIP.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 8
    Publikationsdatum: 2019-01-29
    Beschreibung: Fast nonlinear programming methods following the all-at-once approach usually employ Newton's method for solving linearized Karush-Kuhn-Tucker (KKT) systems. In nonconvex problems, the Newton direction is only guaranteed to be a descent direction if the Hessian of the Lagrange function is positive definite on the nullspace of the active constraints, otherwise some modifications to Newton's method are necessary. This condition can be verified using the signs of the KKT's eigenvalues (inertia), which are usually available from direct solvers for the arising linear saddle point problems. Iterative solvers are mandatory for very large-scale problems, but in general do not provide the inertia. Here we present a preconditioner based on a multilevel incomplete $LBL^T$ factorization, from which an approximation of the inertia can be obtained. The suitability of the heuristics for application in optimization methods is verified on an interior point method applied to the CUTE and COPS test problems, on large-scale 3D PDE-constrained optimal control problems, as well as 3D PDE-constrained optimization in biomedical cancer hyperthermia treatment planning. The efficiency of the preconditioner is demonstrated on convex and nonconvex problems with $150^3$ state variables and $150^2$ control variables, both subject to bound constraints.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 9
    facet.materialart.
    Unbekannt
    Publikationsdatum: 2020-08-05
    Beschreibung: This article describes the main concepts and techniques that have been developed during the last year at ZIB to solve dimensioning and routing optimization problems for IP networks. We discuss the problem of deciding if a given path set corresponds to an unsplittable shortest path routing, the fundamental properties of such path sets, and the computational complexity of some basic network planning problems for this routing type. Then we describe an integer-linear programming approach to solve such problems in practice. This approach has been used successfully in the planning of the German national education and research network for several years.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 10
    Publikationsdatum: 2016-06-09
    Beschreibung: In this review article we discuss different techniques to solve numerically the time-dependent Schrödinger equation on unbounded domains. We present in detail the most recent approaches and describe briefly alternative ideas pointing out the relations between these works. We conclude with several numerical examples from different application areas to compare the presented techniques. We mainly focus on the one-dimensional problem but also touch upon the situation in two space dimensions and the cubic nonlinear case.
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    Sprache: Englisch
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  • 11
    Publikationsdatum: 2016-06-09
    Beschreibung: We discuss first order optimality conditions for state constrained optimal control problems. Our concern is the treatment of problems, where the solution of the state equation is not known to be continuous, as in the case of boundary control in three space dimensions or optimal control with parabolic partial differential equations. We show existence of measure valued Lagrangian multipliers, which have just enough additional regularity to be applicable to all possibly discontinuous solutions of the state equation.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 12
    Publikationsdatum: 2021-08-05
    Beschreibung: We address the property checking problem for SoC design verification at the register transfer level (RTL) by integrating techniques from integer programming, constraint programming, and SAT solving. Specialized domain propagation and preprocessing algorithms for individual RTL operations extend a general constraint integer programming framework. Conflict clauses are learned by analyzing infeasible LPs and deductions, and by employing reverse propagation. Experimental results show that our approach outperforms SAT techniques for proving the validity of properties on circuits containing arithmetics.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 13
    Publikationsdatum: 2016-06-09
    Beschreibung: An adjustment scheme for the relaxation parameter of interior point approaches to the numerical solution of pointwise state constrained elliptic optimal control problems is introduced. The method is based on error estimates of an associated finite element discretization of the relaxed problems and optimally selects the relaxation parameter in dependence on the mesh size of discretization. The finite element analysis for the relaxed problems is carried out and a numerical example is presented which confirms our analytical findings.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 14
    Publikationsdatum: 2020-08-05
    Beschreibung: In this thesis, we study multicommodity routing problems in networks, in which commodities have to be routed from source to destination nodes. Such problems model for instance the traffic flows in street networks, data flows in the Internet, or production flows in factories. In most of these applications, the quality of a flow depends on load dependent cost functions on the edges of the given network. The total cost of a flow is usually defined as the sum of the arc cost of the network. An optimal flow minimizes this cost. A main focus of this thesis is to investigate online multicommodity routing problems in networks, in which commodities have to be routed sequentially. Arcs are equipped with load dependent price functions defining routing costs, which have to be minimized. We discuss a greedy online algorithm that routes (fractionally) each commodity by minimizing a convex cost function that depends on the previously routed flow. We present a competitive analysis of this algorithm and prove upper bounds of (d+1)^(d+1) for polynomial price functions with nonnegative coefficients and maximum degree d. For networks with two nodes and parallel arcs, we show that this algorithm returns an optimal solution. Without restrictions on the price functions and network, no algorithm is competitive. We also investigate a variant in which the demands have to be routed unsplittably. In this case, it is NP-hard to compute the offline optimum. Furthermore, we study selfish routing problems (network games). In a network game, players route demand in a network with minimum cost. In this setting, we study the quality of Nash equilibria compared to the the system optimum (price of anarchy) in network games with nonatomic and atomic players and spittable flow. As a main result, we prove upper bounds on the price of anarchy for polynomial latency functions with nonnegative coefficients and maximum degree d, which improve upon the previous best ones.
    Beschreibung: Diese Arbeit befasst sich mit Mehrgüterflussproblemen, in denen Güter mit einer bestimmten Rate durch ein gegebenes Netzwerk geleitet werden müssen. Mithilfe von Mehrgüterflussproblemen können zum Beispiel Verkehrsflüsse in Strassenverkehrsnetzen oder im Internet modelliert werden. In diesen Anwendungen wird die Effizienz von Routenzuweisungen für Güter durch lastabhängige Kostenfunktionen auf den Kanten eines gegebenen Netzwerks definiert. Die Gesamtkosten eines Mehrgüterflüsses sind durch die Summe der Kosten auf den Kanten definiert. Ein optimaler Mehrgüterfluss minimiert diese Gesamtkosten. Ein wesentlicher Bestandteil dieser Arbeit ist die Untersuchung sogenannter Online Algorithmen, die Routen für bekannte Güternachfragen berechnen, ohne vollständiges Wissen über zukünftige Güternachfragen zu haben. Es konnte ein Online Algorithmus gefunden werden, dessen Gesamtkosten für polynomielle Kostenfunktionen mit endlichem Grad nicht beliebig von denen einer optimalen Lösung abweichen. Für die Berechung einer optimalen Lösung müssen alle Güternachfragen a priori vorliegen. Dieses Gütekriterium gilt unabhängig von der gewählten Netzwerktopologie oder der Eingabesequenz von Gütern. Desweiteren befasst sich diese Arbeit mit der Effizienz egoistischer Routenwahl einzelner Nutzer verglichen zu einer optimalen Routenwahl. Egoistisches Verhalten von Nutzern kann mithilfe von nichtkooperativer Spieltheorie untersucht werden. Nutzer werden als strategisch agierende Spieler betrachtet, die ihren Profit maximieren. Als Standardwerkzeug zur Analyse solcher Spiele hat sich das Konzept des Nash Gleichgewichts bewährt. Das Nash Gleichweicht beschreibt eine stabile Strategieverteilung der Spieler, in der kein Spieler einen höheren Profit erzielen kann, wenn er einseitig seine Strategie ändert. Als Hauptergebnis dieser Arbeit konnte für polynomielle Kostenfunktionen mit endlichem Grad gezeigt werden, dass die Gesamtkosten eines Nash Gleichgewichts für sogennante atomare Spieler, die einen diskreten Anteil der gesamten Güternachfrage kontrollieren, nicht beliebig von den Gesamtkosten einer optimalen Lösung abweichen. In this thesis, we study multicommodity routing problems in networks, in which commodities have to be routed from source to destination nodes. Such problems model for instance the traffic flows in street networks, data flows in the Internet, or production flows in factories. In most of these applications, the quality of a flow depends on load dependent cost functions on the edges of the given network. The total cost of a flow is usually defined as the sum of the arc cost of the network. An optimal flow minimizes this cost. A main focus of this thesis is to investigate online multicommodity routing problems in networks, in which commodities have to be routed sequentially. Arcs are equipped with load dependent price functions defining routing costs, which have to be minimized. We discuss a greedy online algorithm that routes (fractionally) each commodity by minimizing a convex cost function that depends on the previously routed flow. We present a competitive analysis of this algorithm and prove upper bounds of (d+1)^(d+1) for polynomial price functions with nonnegative coefficients and maximum degree d. For networks with two nodes and parallel arcs, we show that this algorithm returns an optimal solution. Without restrictions on the price functions and network, no algorithm is competitive. We also investigate a variant in which the demands have to be routed unsplittably. In this case, it is NP-hard to compute the offline optimum. Furthermore, we study selfish routing problems (network games). In a network game, players route demand in a network with minimum cost. In this setting, we study the quality of Nash equilibria compared to the the system optimum (price of anarchy) in network games with nonatomic and atomic players and spittable flow. As a main result, we prove upper bounds on the price of anarchy for polynomial latency functions with nonnegative coefficients and maximum degree d, which improve upon the previous best ones.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 15
    Publikationsdatum: 2020-11-16
    Beschreibung: The timetable is the essence of the service offered by any provider of public transport'' (Jonathan Tyler, CASPT 2006). Indeed, the timetable has a major impact on both operating costs and on passenger comfort. Most European agglomerations and railways use periodic timetables in which operation repeats in regular intervals. In contrast, many North and South American municipalities use trip timetables in which the vehicle trips are scheduled individually subject to frequency constraints. We compare these two strategies with respect to vehicle operation costs. It turns out that for short time horizons, periodic timetabling can be suboptimal; for sufficiently long time horizons, however, periodic timetabling can always be done in an optimal way'.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 16
    Publikationsdatum: 2020-12-15
    Beschreibung: This thesis describes the algorithm IS-OPT that integrates scheduling of vehicles and duties in public bus transit. IS-OPT is the first algorithm which solves integrated vehicle and duty scheduling problems arising in medium sized carriers such that its solutions can be used in daily operations without further adaptions. This thesis is structured as follows: The first chapter highlights mathematical models of the planning process of public transit companies and examines their potential for integrating them with other planning steps. It also introduces descriptions of the vehicle and the duty scheduling problem. Chapter 2 motivates why it can be useful to integrate vehicle and duty scheduling, explains approaches of the literature, and gives an outline of our algorithm IS-OPT. The following chapters go into the details of the most important techniques and methods of IS-OPT: In Chapter 3 we describe how we use Lagrangean relaxation in a column generation framework. Next, in Chapter 4, we describe a variant of the proximal bundle method (PBM) that is used to approximate linear programs occurring in the solution process. We introduce here a new variant of the PBM which is able to utilize inexact function evaluation and the use of epsilon-subgradients. We also show the convergence of this method under certain assumptions. Chapter 5 treats the generation of duties for the duty scheduling problem. This problem is modeled as a resourceconstraint- shortest-path-problem with non-linear side constraints and nearly linear objective function. It is solved in a two-stage approach. At first we calculate lower bounds on the reduced costs of duties using certain nodes by a new inexact label-setting algorithm. Then we use these bounds to speed up a depth-first-search algorithm that finds feasible duties. In Chapter 6 we present the primal heuristic of IS-OPT that solves the integrated problem to integrality. We introduce a new branch-and-bound based heuristic which we call rapid branching. Rapid branching uses the proximal bundle method to compute lower bounds, it introduces a heuristic node selection scheme, and it utilizes a new branching rule that fixes sets of many variables at once. The common approach to solve the problems occurring in IS-OPT is to trade inexactness of the solutions for speed of the algorithms. This enables, as we show in Chapter 7, to solve large real world integrated problems by IS-OPT. The scheduled produced by IS-OPT save up to 5% of the vehicle and duty cost of existing schedules of regional and urban public transport companies.
    Beschreibung: Diese Arbeit beschreibt den Algorithmus IS-OPT, welcher der erste Algorithmus ist, der integrierte Umlauf- und Dienstplanungsprobleme für mittelgroße Verkehrsunternehmen löst und dabei alle betrieblichen Einzelheiten berücksichtigt. Seine Lösungen können daher direkt in den täglichen Betrieb übernommen werden. Im ersten Kapitel werden mathematische Modelle für verschiedenen Probleme aus dem Planungsprozess von Nahverkehrsunternehmen beschrieben. Es werden Ansätze zur Integration der einzelnen Probleme untersucht. In diesem Kapitel werden außerdem das Umlauf- und das Dienstplanungsproblem eingeführt. Kapitel 2 motiviert, warum Integration von Umlauf- und Dienstplanung hilfreich ist oder in welchen Fällen sie sogar unabdingbar ist; es gibt einen Überblick über die vorhanden Literatur zur integrierten Umlauf- und Dienstplanung und umreißt unseren Algorithmus IS-OPT. Die weiteren Kapitel behandeln die in IS-OPT verwendeten Methoden: In Kapitel 3 beschreiben wir, wie Spaltenerzeugung für lineare Programme mit Lagrange-Relaxierung und Subgradienten-Verfahren kombiniert werden kann. In Kapitel 4 wird unsere Variante der proximalen Bündelmethode beschrieben. Diese wird benutzt um näherungsweise primale und duale Lösungen von lineare Programmen zu berechnen. Unsere Variante ist angepasst, um auch mit ungenauer Funktionsauswertung und Epsilon-Subgradienten arbeiten zu können. Wir zeigen die Konvergenz dieser Variante unter bestimmten Annahmen. Kapitel 5 behandelt das Erzeugen von Diensten für das Dienstplanungsproblem. Dieses Problem ist als ein Kürzeste-Wege-Problem mit nichtlinearen Nebenbedingungen und fast linearer Zielfunktion modelliert. Wir lösen es, indem zuerst Schranken für die reduzierten Kosten von Diensten, die bestimmte Knoten benutzen, berechnet werden. Diese Schranken werden benutzt, um in einem Tiefensuchalgorithmus den Suchbaum klein zu halten. Im Kapitel 6 präsentieren wir die neu entwickelte Heuristik "Rapid Branching", die eine ganzzahlige Lösung des integrierten Problems berechnet. Rapid Branching kann als eine spezielle Branch-and-Bound-Heuristik gesehen werden, welche die Bündelmethode benutzt. In den Knoten des Suchbaums können mehrere Variablen auf einmal fixiert werden, die mit Hilfe einer Perturbationsheuristik ausgewählt werden. In Kapitel 7 schließlich zeigen wir, daß wir mit IS-OPT auch große Probleminstanzen aus der Praxis lösen können und dabei bis zu 5% der Fahrzeug- und Dienstkosten sparen können.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 17
    Publikationsdatum: 2020-12-14
    Beschreibung: This paper reviews George Dantzig's contribution to integer programming, especially his seminal work with Fulkerson and Johnson on the traveling salesman problem
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 18
    Publikationsdatum: 2020-11-13
    Beschreibung: Abstract The cost-efficient design of survivable optical telecommunication networks is the topic of this thesis. In cooperation with network operators, we have developed suitable concepts and mathematical optimization methods to solve this comprehensive planning task in practice. Optical technology is more and more employed in modern telecommunication networks. Digital information is thereby transmitted as short light pulses through glass fibers. Moreover, the optical medium allows for simultaneous transmissions on a single fiber by use of different wavelengths. Recent optical switches enable a direct forwarding of optical channels in the network nodes without the previously required signal retransformation to electronics. Their integration creates ongoing optical connections,which are called lightpaths. We study the problem of finding cost-efficient configurations of optical networks which meet specified communication requirements. A configuration comprises the determination of all lightpaths to establish as well as the detailed allocation of all required devices and systems. We use a flexible modeling framework for a realistic representation of the networks and their composition. For different network architectures, we formulate integer linear programs which model the design task in detail. Moreover, network survivability is an important issue due to the immense bandwidths offered by optical technology. Operators therefore request for designs which perpetuate protected connections and guarantee for a defined minimum throughput in case of malfunctions. In order to achieve an effective realization of scalable protection, we present a novel survivability concept tailored to optical networks and integrate several variants into the models. Our solution approach is based on a suitable model decomposition into two subtasks which separates two individually hard subproblems and enables this way to compute cost-efficient designs with approved quality guarantee. The first subtask consists of routing the connections with corresponding dimensioning of capacities and constitutes a common core task in the area of network planning. Sophisticated methods for such problems have already been developed and are deployed by appropriate integration. The second subtask is characteristic for optical networks and seeks for a conflict-free assignment of available wavelengths to the lightpaths using a minimum number of involved wavelength converters. For this coloring-like task, we derive particular models and study methods to estimate the number of unavoidable conversions. As constructive approach, we develop heuristics and an exact branch-and-price algorithm. Finally, we carry out an extensive computational study on realistic data, provided by our industrial partners. As twofold purpose, we demonstrate the potential of our approach for computing good solutions with quality guarantee, and we exemplify its flexibility for application to network design and analysis.
    Schlagwort(e): ddc:510
    Sprache: Englisch
    Materialart: doctoralthesis , doc-type:doctoralThesis
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  • 19
    Publikationsdatum: 2019-01-29
    Beschreibung: Parabolic reaction-diffusion systems may develop sharp moving reaction fronts which pose a challenge even for adaptive finite element methods. We propose a method to transform the equation into an equivalent form that usually exhibits solutions which are easier to discretize, giving higher accuracy for a given number of degrees of freedom. The transformation is realized as an efficiently computable pointwise nonlinear scaling that is optimized for prototypical planar travelling wave solutions of the underlying reaction-diffusion equation. The gain in either performance or accuracy is demonstrated on different numerical examples.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 20
    Publikationsdatum: 2016-06-09
    Beschreibung: We propose and analyse an interior point path-following method in function space for state constrained optimal control. Our emphasis is on proving convergence in function space and on constructing a practical path-following algorithm. In particular, the introduction of a pointwise damping step leads to a very efficient method, as verified by numerical experiments.
    Schlagwort(e): ddc:510
    Sprache: Englisch
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  • 21
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 91-111 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The clam Mya differs from other pelecypods which have been investigated in this respect in having most of the reserve nutritive materials formed within the vacuolated follicle cells of the gonads instead of within the very limited amount of mesenchymatous connective tissue of the visceral mass. The profusely branching tubular gonads originate from two groups of primordial germ cells situated in the position of the future genital apertures. The germinal primordia soon become differentiated into two types of nuclei, one of which becomes associated with the large, vacuolated follicle cells, which form the principal volume of the gonadal tissue, while the other type proliferates to form the primary gonia which become widely scattered along the walls of each alveolus.There is much degeneration and cytolysis during gametogenesis in both sexes, with the accumulation of characteristic inclusions within the follicle cells. Atypical spermatogenesis followed by cytolysis occurs throughout the year but the normal method only in preparation for spawning. No evidence of protandry or change of sex was obtained; only three hermaphrodites were found in the examination of more than 1000 individuals.
    Zusätzliches Material: 23 Ill.
    Materialart: Digitale Medien
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  • 22
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 1-2 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 23
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The regeneration of muscle in larval Amblystoma punctatum is preceded by an extensive dedifferentiation of the old muscles of the limb stump. The process of muscle dedifferentiation consists in a separation of muscle nuclei, surrounded by a small amount of cytoplasm, from the injured ends of the muscle fibers. The dedifferentiation of the cut muscles of the limb stump progresses proximad as far as the origin of the muscles on the humerus and results in a complete transformation of these muscles into undifferentiated cells which appear to contribute to the formation of the regeneration blastema. Shoulder muscles, which were attached to the humerus, also undergo a partial dedifferentiation when their points of insertion on the humerus are destroyed by the degeneration of the perichondrium. These muscles never dedifferentiate, however, for more than one-fourth their original length. The process of dedifferentiation in the shoulder muscles is similar to that found in the cut muscles of the limb stump.The regeneration of the injured muscles occurs in two ways. The shoulder muscles reconstitute themselves by means of terminal and lateral sarcoplasmic buds formed near the distal regions of the muscle fibers. The muscles of the limb proper, distal to the shoulder, differentiate out of local aggregations of blastema cells. No myoblasts were observed.The regeneration blastema arose chiefly from dedifferentiated cells of muscle, nerve connective tissue sheath, perichondrium and cartilage.
    Materialart: Digitale Medien
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  • 24
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 25
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 177-218 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The original innominate bone consisted of ischiopubis only. From this developed a dorsally-directed ilium, upon which the dorsal limb muscles, originally arising from fascia, settled, and which thrust dorsalward between roots of the limb plexus, thus dividing the nerves into prozonal (dorsal and ventral) and metazonal (dorsal and ventral) groups. The primitive muscles of the tetrapod hip and thigh comprised a dorsal mass, soon divisible into sheets, innervated by both prozonal and metazonal dorsal nerves, and a similar ventral mass comparably innervated. The original two elements thus became four basic elements, and probably in early mammals or mammal-like reptiles all dually innervated muscles split into singly innervated units. With this four-group basis as the chief criterion, but considering other factors as well, it is possible to homologize the muscles of urodeles (ventral components only), lacertilians, mammals, and birds in entirely satisfactory manner, except for doubt in several instances in which specialization has secondarily obscured the precise relationships. In different mammals there is shown a tendency toward a final fusion of certain unrelated muscle units (biceps plus gluteus longus, human type of biceps, adductor magnus, and tensor fasciae femoris with gluteus maximus).
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
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  • 26
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 27
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 415-443 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: In the blastula stage the roof of the subgerminal cavity is composed of an irregular layer of cells, the nuclei of which lie in the upper or middle part of the cytoplasm.On the floor of the subgerminal cavity groups of already degenerating cells occur. They represent the vegetative pole of the blastula. Almost every cell contains glycogen, and mitotic cells show no special orientation.In the gastrula stage the cells of the area pellucida become regularly arranged as a single-layered, cylindrical epithelium with basally situated nuclei.The yolk endoderm cells are formed from the proliferating upper layer of the area opaca.The embryonic endoderm is formed at the posterior end of the area pellucida by outgrowth of single cells from a circumscribed area, the primitive plate.This plate eventually bends inward to form a typical archenteric canal, through which endoderm continues to invaginate from the epiblast.The endoderm spreads in a cranial and lateral direction until it has formed a complete layer.The epiblast cells lose their glycogen as they invaginate to form endoderm, which is free of glycogen.In the area opaca the upper layer and the yolk endoderm contain glycogen.The mitotic cells of the epiblast of the area pellucida are always orientated horizontally, but in the primitive plate and archenteric canal they are orientated vertically as well.
    Materialart: Digitale Medien
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  • 28
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 559-597 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The larval, metamorphosing and definitive aortic arches of Desmognathus fuscus, Plethodon cinereus, Eurycea bislineata, and Gyrinophilus porphyriticus, described in this paper, were investigated because it was thought possible that, if the fourth or pulmonary arch failed to develop in these lungless forms, a new factor associated with the loss of lungs might be revealed.The salient points of structure disclosed, so far as the problem involved is concerned, are: D. fuscus and P. cinereus develop fourth arches which remain functional in the larvae and adults and supply the pharynx, oesophagus, stomach and skin of the shoulder region. In some instances the fourth arch in the larvae of P. cinereus is reduced in length or entirely lacking in which cases correspondingly less of the fourth arch and more of the third arch is present in the adult. E. bislineata and undoubtedly G. porphyriticus fail to develop fourth arches and hence do not possess these in either the larval or adult states.It is concluded, therefore, that the failure of the fourth arch to develop has evidently not been a factor involved in the advent of lunglessness in plethodontid salamanders. Also, the fact that E. bislineata never develops a fourth arch, yet is able to transform, furnishes additional evidence against Figge's view that Necturus fails to metamorphose because the ventral portion of the fourth arch is absent.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
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  • 29
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 30
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 75-86 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This study is based on serial sections of the occipital and otic regions of a therocephalian from the Tapinocephalus zone. The occipital region as preserved consists of the basioccipitals and exoccipitals. The basioccipital is long and slender and is separated from the more anterior basisphenoid by an unossified zone. The exoccipitals are large and contain a part of the jugular foramen and two foramina for cranial nerve XII.The otic bones are fused together to form a periotic. The most striking feature of the inner ear is the medioventral position of the vestibule. Passing back into the periotic from the vestibule is a deep recessus scala tympani. This recess opens anteriorly into a ventral fenestra in the vestibule, the fenestra rotunda. These structures are similar to those of Dimetrodon and the gorgonopsian.The anterior part of the periotic is projected ventrally to form a basicranial process. This probably arose by intramembranous ossification. The unossified zone between the basioccipital and basisphenoid may represent a persistent basicranial fenestra.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
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  • 31
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 63-73 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A study has been made of the growth of the eye anlage, and of the increase in number of the elements of the dioptric system of larvae of Drosophila melanogaster.In newly hatched larvae the eye rudiment grows fast, but slows down later and becomes nearly stationary during the second half of larval life. The increase in number of elements in the eye disc parallels the growth of the whole anlage and reaches a maximum about 70 hours after hatching. The imaginal disc cells increase in number but not in size, in contrast to other larval cells which increase in size but not in number.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
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  • 32
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 87-117 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The form of the vertebral column is definitely related to its function as a supporting rod, a base for attachment of body and limb muscles, and a protection of the spinal cord and nerves. Primitively composed of a series of simple undifferentiated blocks, it progressively becomes complicated through development of articular processes giving added strength and greater mobility. Simultaneously, the centrum and the neural arch become adapted to withstand tension and compression stresses which vary with the movements possible in different regions of the column. These movements are partially determined by the plane of the zygapophyses and the nature of the intercentral articulation, together with the action of the axial muscles and ligaments.In fish and primitive tetrapods the axial musculature serves as the chief locomotor organ and consists of a series of myomeres extending with little interruption from the head to the tail. In tetrapods the locomotor function is taken over by the limbs and the axial muscles become progressively differentiated into long flexors and extensors of the column and gradually lose their external segmentation.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
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  • 33
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Adult salamanders of Ambystoma tigrinum show a high degree of sexual dimorphism. The normal growth of the urogenital ducts system in relation to the development of the gonads is traced from the sexually indifferent period preceding metamorphosis to sexual maturity at 1 year. Differentiation and growth of secondary sex characters is correlated with spermatogenesis in the male and with growth of ovocytes in the female.Testicular hormone manifests its initial appearance in male differentiation of the wolffian and urinary collecting ducts following metamorphosis. Growth of ovocytes and oviducts begins before metamorphosis and may be assumed to indicate the initial appearance of the ovarian hormone. Females retain the larval arrangement of wolffian and urinary ducts. The oviducts of the male regress during the period of rapid male differentiation. This suggests the possibility of antagonistic activity of the male hormones in Ambystoma.
    Zusätzliches Material: 16 Ill.
    Materialart: Digitale Medien
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  • 34
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 143-161 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A batch of fifty newts was subjected to complete food deprivation for a period of 4 months. During the experiment twenty-two individuals died and twenty-eight were killed at intervals. From the end of the second month the erythrocytes began to show in increasingly greater numbers a progressive alteration in the nucleo-cytoplasmic ratio. The nucleus of these atypical erythrocytes gradually enlarged and ultimately occupied the entire cytosome. Meanwhile the nuclear reticulum became extremely fine and closely meshed, eventually appearing practically homogeneous and relatively chromophobic. The end result was complete dissolution. The leukocytes became greatly reduced in number, the eosinophils disappearing completely. The neutrophils and basophils were agranular in the blood smears. The erythrocyte transformations represent late results of a chain of factors: cytoplasmic hypotonicity, nuclear endosmosis, attenuation and fenestration of nuclear membrane. The subcapsular lymphogranulocytopoietic tissue of the liver had almost completely disappeared. The spleen was greatly reduced in size; it was essentially lymphoid in character and erythrocytopoietic activity had ceased practically completely. Complete restoration of normal conditions in blood, liver and spleen was effected by the end of 2 weeks by feeding with earthworms. The regenerating blood showed many naked nuclei of disintegrating atypical erythrocytes, many immature erythrocytes in mitosis, increased number of small lymphocytes (lymphoid hemoblasts), large but variable numbers of microcytes, many giant thrombocytes and normal granulocytes.
    Materialart: Digitale Medien
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  • 35
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Colloidal carbon injected into the coelom of the larval lamprey, Ammocoetes, is taken up directly by the pronephric tubules. Due to the absence of nephrostomes the mesonephric tubules do not function in a similar way. The tubules of neither show any intracellular deposition of carbon. The reticular elements which support both these kidneys exhibit pronounced phagocytic and hemocytopoietic activity. Carbon in either a free or included form reaches all the other organs both as a result of direct invasion or secondary distribution by the vascular system. The liver is the only organ whose vascular endothelium exhibits cytopoietic properties. To the diffuse spleen as a site of blood cell formation thus should be added the reticular tissue of the pronephros and mesonephros and the vascular endothelium of the liver. Playing a minor role in a similar way are the intestinal mucosa exclusive of that in the typhlosole and the spongy tissue dorsal to the neural tube.
    Materialart: Digitale Medien
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  • 36
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 37
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 181-205 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: In an earlier paper (Slifer, '37) experiments were reported which showed that in Melanoplus differentialis eggs the hatching enzyme, which destroys the white cuticle, is secreted by the pleuropodia (appendages of the first abdominal segment of the embryo) during the last few days of incubation. In the present report the development and differentiation of the pleuropodia, together with the cytological changes which occur in them before, during and after they become functional, have been followed. The time at which the secretion granules are discharged from the pleuropodial cells was found to be closely correlated with the time at which the tough, white cuticle begins to disintegrate. The cytological evidence, then, supports the author's earlier conclusion, based upon experimental work, that the pleuropodia secrete the hatching enzyme.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 38
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 207-217 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Comparison of intramembral and trunk/limb proportions in the roadrunner (Geococcyx) and two related genera of cuckoos (Coccyzus and Crotophaga), together with a consideration of their habits of locomotion, lead to the following two generalizations: (1) The incipient cursorial leg of more primitive, arboreal birds, with the metatarsus shorter than the femur, is not an efficient mechanism for bipedal terrestrial locomotion. The direct adaptation to the cursorial habit in terrestrial birds lies in the further elongation of the whole leg, the distal segments undergoing a relatively greater elongation than the femur; the greatest degree of elongation is shown by the most distal segment. (2) When the development of terrestrial, cursorial habits in birds leads to diminished use, or discuse, of the wings as organs of locomotion, the wing skeleton becomes reduced in length; each segment of the wing is reduced, but the degree of reduction is greatest in the more distal segments. It is probable that reduction appears first in the most distal segment and later successively in each segment proceeding proximally therefrom.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
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  • 39
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 219-227 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The median cord arises as a hypodermal invagination along the midline from stomodeum to end of tenth abdominal ganglion. It separates from the hypoderm, but does not differentiate into any tissue; apparently it degenerates.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
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  • 40
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 289-299 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: There are 19 chromosomes in diploid cells of male Paratylotropidia brunneri; of these, four are V-shaped multiples. There are twenty chromosomes in diploid cells of females; of these, four are V-shaped multiples. If the two arms of each multiple are counted as separate chromosomes, we have the usual number of chromosomes for the Acrididae, i.e., twenty-three in male and twenty-four in female.There are nine chromosomes in the first spermatocyte divisions: seven tetrads, one octad and a decad. The latter is made up of the accessory chromosome associated with an octad.One of the V-shaped multiples in the male is limited to that sex. The homologue of one of the dyads of which it is composed is a free dyad, the homologue of the other forms a V-shaped multiple with the accessory chromosome. The V-shaped multiple limited to the male shows differential heteropycosis in the prophases of the first spermatocyte. There is evidence that its homologous parts are isolated from each other as far as crossingover is concerned.A study of the first maturation division of the heterogametic sex is essential for the identification of the sex chromosome.
    Materialart: Digitale Medien
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  • 41
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 229-261 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Although thoracic diverticula of the aorta ending dorsally in pulsatile organs were discovered by Brocher as early as 1917 no detailed account of their structure was published. The condition of these structures in the adult was not investigated and their development through larval instars was not followed. Brocher's later papers announced the discovery of similar organs in the orders Orthoptera, Coleoptera and Lepidoptera. In 1931 E. Meyer described in some detail pulsatile organs in the Ephemerida. In general these accounts are either superficial or of doubtful interpretation.The present paper deals with the Odonata and stresses the Anisoptera. Anax junius has been studied as the type both anatomically and histologically in all stages of larva and imago except the first four instars. Other types have been compared with Anax, and some of the other orders mentioned have been checked for presence and nature of these organs.Aortic diverticula and pulsatile organs occur in all Odonata both larval and adult. These are derived from the same origins and their histology is that of the membranes involved in aortic and body walls. Through inference from morphology and from physiological examination it appears that pulsatile organs (1) supplement heart action, perhaps substituting for it during emergence. (2) assist in the functioning of the ostia and ostial glands, and (3) may even be important in production and distribution of hormones.
    Materialart: Digitale Medien
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  • 42
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The germinal epithelium was studied in an effort to determine its role in postpubertal ovogenesis. Active and inactive areas of epithelium were observed regardless of the oestrous periods. The active areas, exemplified by numerous mitoses and a frequent stratification of the epithelium, are foci for egg cell production.Egg cells are produced from the germinal epithelium by: activation, migration and transformation of single germinal epithelial cells; migration and differentiation of nests of cells; ingrowths of cords of cells.Young ova in the cortex of the ovary are at first surrounded by a single layer of flattened follicular cells of germinal epithelial origin. In the subsequent development of the follicle stratified layers make their appearance. The zona pellucida appears as a well-defined structure coincident with the stratification of the follicular layers.The follicular cavity develops as a split between the follicular cells at one side of the follicle. In the mature follicle the cavity is broad and contains liquor folliculi. The theca interna and externa are not distinguishable until the follicle is highly cellular.
    Materialart: Digitale Medien
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  • 43
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The spermatogenetic cycle of the testis of the musk turtle is limited to the summer months of the year, and closely parallels that of the anuran Amphibia. Spermatozoa are present in the testis from September to May, and breeding may occur in either fall or spring. A pronounced increase in the size of the epididymis and a corresponding decrease in the size of the testis occurs at the end of the cycle (September).During the months of March, April and May, all spermatozoa are eliminated from the seminal tubules, and the germinal epithelium is built up in preparation for spermatogenesis. Spermatogonial divisions occur in small numbers in May, and the division tempo increases during June. Primary spermatocytes and maturation divisions appear after the middle of June, and continue through July and August. Spermiogenesis begins in late July, is in full progress in August, and is practically completed by October. Laboratory specimens usually show an active spermatogenesis in winter, but it is not probable that a second spermatogenetic cycle occurs in specimens under normal hibernating conditions.No seasonal changes are observed in the interstitial cells of the testis, and no seasonally variable secondary sex characters are known for turtles. Special studies of the problem are being conducted.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 44
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 345-361 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This species represents a typical example of protandric consecutive sexuality, the male phase becoming functional at a very early age, when the body has reached a length of only 3 to 7 mm. Those males which become functional earliest usually seek the association of older individuals in the female phase; others, maturing later, are more likely to remain solitary. Mated males have accentuated masculine characteristics and retain the male phase longer than solitary individuals or those that are isolated experimentally. Unfavorable environmental conditions postpone or prevent functional sexuality and terminate the male phase promptly without inaugurating the female phase. The influence of the female in accentuating the sexuality of the male is thought to be due to stimuli received by the latter through sense organs in tentacles and penis and mediated by the nervous system through hormonal secretions. Termination of the male phase and transition to the functional female are comparable to metamorphosis from the immature to the mature condition in other animals and, like metamorphosis, the primary (male) sexual phase can be abbreviated or prolonged experimentally, but the sequence cannot be reversed.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
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  • 45
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Data concerning the seasonal distribution of twenty-two species of nudibranchs are recorded for a period of 9 months. The occurrence of copulation and of egg laying for these animals in the laboratory aquaria is recorded for the same period. These data indicate that the seasonal distribution of certain species is well marked, and that there is in many cases a definite breeding season.The characteristics of the egg ribbons of these nudibranchs are described, and figured by means of photographs. These egg ribbons approach the mathematical form of a spiral of Archimedes. In every case observed, the ribbon was deposited in a counter-clockwise direction, viewed dorsally.The relationship between these observations and earlier work on the life histories of the nudibranchs is discussed.
    Zusätzliches Material: 5 Tab.
    Materialart: Digitale Medien
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  • 46
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Salivary gland nuclei in Chironomus regularly show large, conspicuous nucleoli. In Sciara no true nucleoli have been found, but sometimes certain particular chromosome regions expand greatly, forming ‘puffs’ or ‘bulbs,’ somewhat nucleolus-like in nature. Detailed study has been made of the chromosome structure in the affected regions in both genera.In the nucleolar regions of Chironomus the banded structure of the chromosome is distinctly modified. In the case of the large nucleolus the chromosome breaks up into a heavy network in which solid discs are replaced by interconnected chromatic spheres and granules, extending out somewhat into the clear nucleolar substance. In the case of the smaller nucleolus, Balbiani's ring, the banded structure is less disturbed. A chromatic network, resembling a system of rootlets, runs out from the chromatic bands into the clear nucleolar substance.In Sciara ocellaris the ‘puff’ regions are at times normally banded, but at other times in the condition described as ‘puffed.’ The same is true of the ‘bulb’ regions. The relation between nucleoli, puffs and bulbs is discussed. Also that between ‘heterochromatin’ and ‘euchromatin.’ Evidence seems to indicate that the latter are merely extremes in a continuous range involving different relative amounts of chromatic and achromatic materials. The ‘puff’ regions appear to be structurally similar to the chromocenter in Drosophila.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 47
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 48
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 397-419 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The summary of this paper is as follows:1From an examination of 108 ovaries from eighty-nine individuals it was apparent that, in the cat a certain but variable amount of degeneration of primary follicles occurs in all life epochs.2The primary oocytes undergo the degeneration, while the follicle cells remain for an undetermined time.3The most profound instances of such degeneration were encountered in kittens of 6 to 9 weeks, accompanying or follwing the resolution of the egg cords into primary follicles and the establishment of the cortical or marginal zone. A sporadic degeneration of young oocytes occurs at earlier periods.4No evidence was seen of a new formation of egg cells from the residual follicle cells after the degeneration of the oocytes. The degenerations of the 6 to 9 weeks epoch are not believed to be of universal occurrence.5No adequate evidence was encountered of a new formation of egg cells from the surface epithelium, either before or after sexual maturity.6No evidence linking the degeneration of primary follicles with the estrous cycle was seen.7The stock of primary follicles established in the first few weeks after birth is believed to be adequate for the growth of graafian.
    Materialart: Digitale Medien
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  • 49
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 421-439 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The maturation of the germ cells of the two hermaphroditic species, Curtisia foremanii (Girard) and Bdelloura candida (Girard) has supplied the material for this chromosome study.Both species of flatworms are believed by the author to possess a diploid number of twelve chromosomes and a haploid number of six, although Curtisia foremanii has previously been reported as having a smaller and variable number of chromosomes.A tendency of the chromatids comprising individual chromosomes to separate from one another at certain times was noted in both species. This action results in giving the appearance of a larger number of chromosomes than the germ cells actually possess. A further source of apparent increase in chromosome number in the Curtisia oocytes, after treatment with the usual Allen's B3 and B15 and Heidenhain's iron haematoxylin, is the presence of some deeply staining, non-chromatin material.No significant differences in number, form and behavior of chromosomes of male and female complexes were noted, with the possible exception of the tendency of the chromatids to separate from one another, to be greater in the female than in male germ cells.
    Zusätzliches Material: 11 Ill.
    Materialart: Digitale Medien
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  • 50
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 441-475 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Four cases of gynandry in American spiders present the following morphologic deviations: The specimen belonging to Neoantistea agilis (Keyserling) externally is a bilateral gynandromorph with distortion of the single male palp, with half of the epigynum nearly normal; internally both testes and ovaries are present. The Drassodes neglectus (Keyserling) is not a completely developed bilateral gynandromorph. One side has a normal male palp, a larger chelicera and longer legs than the other, the epigynum is complete and normal; internally only degenerate ovaries are present. The Linyphiid, near Bathyphantes, is three-quarters female, the only male organ being an imperfectly developed male palp. Ovaries are well developed but immature, whereas the epigynum is complete. In the Pardosa sternalis (Thorell) the anterior part of the body is male, as indicated by the swollen palps and the length of the legs; the epigynum is completely developed, but internal reproductive organs are missing except for a very much aborted ovary. The bisexuality in all cases has caused degeneration or abnormalities in the reproductive structures.Included is a tabulation of all recorded instances of gynandry in spiders, arranged according to the type of abnormality. The term ‘leg-index’ is introduced to express ratio between length of the leg and length of cephalothorax.
    Zusätzliches Material: 13 Ill.
    Materialart: Digitale Medien
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  • 51
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Centrifuging the eggs of Rana pipiens in the early gastrula stage prevents the formation of the hypophysis in some of the tadpoles. The absence of the melanophorotropic hormone normally secreted by the hypophysis seems to be responsible for the contraction of the pigment cells. In addition, there are actually fewer pigment cells present in both the dermal and epidermal layers of the light tadpoles than there are in the controls. The paleness, therefore, of the tadpoles seems to be due to both a contraction of the pigment cells present and to an actual reduction in their number. The failure of the hypophysis to develop was brought about by centrifuging at an earlier stage in development of the embryo than in previous extirpation studies. The effects produced by centrifuging that are responsible for the failure of the hypophysis to develop are unknown. However, it is suggested that interference in some way with the presumptive hypophysis-forming tissue has resulted in an inactivation of its inductive potencies.
    Materialart: Digitale Medien
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  • 52
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 491-529 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This paper is based on evidence obtained from sectioned skull of Galesaurus planiceps, Owen. Width-length index of skull is 67.7; height-width index 47.6. Dental formula is: \documentclass{article}\pagestyle{empty}\begin{document}$ \frac{{{\rm I\; 3\; or\; 4}}}{{{\rm I\; ?}}} $\end{document}, \documentclass{article}\pagestyle{empty}\begin{document}$ \frac{{{\rm C\; 1}}}{{{\rm C\; 1}}} $\end{document}, \documentclass{article}\pagestyle{empty}\begin{document}$ \frac{{{\rm PC\; 7}}}{{{\rm PC\; 9}}} $\end{document}. Length of prevomer is 24.0 mm., that of skull 62.0 mm. Maxilla contains cavity which appears to be equivalen of sinus maxillaris of mammals. Ear structure shows large internal auditory meatus. There is no evidence that horizontal and posterior semicircular canals pass through bone. Fenestra ovalis is large. Parasphenoid, basisphenoid, and basioccipital are fused. Parasphenoid consists of short body and a medial anterior process. Sella turcica lacks floor, probably due to erosion. Detached bone may be sphenethmoid. Dentary contains two canals, probably vascular. Comparisons with related forms lead to following conclusions: (1) Specimen is of young animal. (2) Dental succession of postcanines, distichical replacement of postcanines, long prevomer, short parasphenoid, incomplete osseous incasement of semicircular canals, and other characteristics label Galesaurus as primitive cynodont. (3) Reduction of parasphenoid and development of prevomer support Broom's view that Ictidosaurus is not a cynodont. (4) Prevomer as nasal septum; fusion of parasphenoid, basisphenoid, and basioccipital; large lacrimal, splenial, and articular; and other characteristics indicate that Galesaurus is off line leading to mammals. (5) In certain respects cynodonts are more mammal-like than gorgonopsians.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
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  • 53
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 63 (1938), S. 531-587 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The development of the cranial musculature of Amblystoma punctatum is described in detail, for both larva and adult. In addition, a brief account of the innervation of each muscle is given. The study of normal development is supplemented by extirpation experiments performed on embryos in early stages of development. These extirpations include the mesodermal head segments, mesoderm of mandibular, hyoid, second branchial, third branchial arches, and somites 1, 2 and 3. The eye muscles are found to develop from the mesodermal head segments in precisely the same manner as in other classes of vertebrates; head segmentation of Amphibia, though less accentuated, is shown to be homologous with that of other classes. The remaining extirpation experiments corroborate, in general, the finding from normal development studies. An attempt is made to summarize in tabular form the prospective fate of the prechordal plate and parachordal mesoderm, the two earliest divisions of the head mesoderm, with regard to their complete muscle derivatives.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
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  • 54
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938) 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
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  • 55
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 3-15 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Comparisons have been made of the weights of the suprarenals of 525 mature female dogs in dioestrus, oestrus, pregnancy and lactation. Tables and graphs show that there was a slight increase in the size of the suprarenals during oestrus. There was hypertrophy of both the cortex and the medulla in the oestrous dogs. Only slight increase was shown in the weights of the glands of pregnant animals when the net body weight was considered and no increase when the total body weight was used in the study. There was no hypertrophy of the glands of lactating animals.There was only a slight variation in the seasonal occurrence of oestrus. From 34 to 37% of the total numbers of mature females examined in the seasons were found to be in oestrus. From 13 to 16% of the total numbers were found to be pregnant.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
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  • 56
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Nucleoli in the germ cells of certain Orthoptera, Hemiptera and the crayfish have been studied. In Ceuthophilus (camel cricket) these bodies are found to be definitely connected with chromatin threads and are believed to be products of chromatin.The large structure in the ova of Nemobius (cricket) is interpreted as a nucleolus because of its very irregular behavior and apparent complete disappearance.It is found that some of the nucleoli of Gelastocoris (toad bug) arise within the chromatin threads.Observations on Cambarus (crayfish) fail to show nucleolar extrusion, a phenomenon which has formerly been reported for this form.The unique behavior and fate of the nucleolar material in Pselliopus (true bug) is described. In this species the nucleolar material is added to and becomes part of the general oxychromatin network of the nucleus.This study fully supports the opinion that nucleoli have a chromatin origin.
    Materialart: Digitale Medien
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  • 57
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A new limb skeleton will form in regenerating limbs of the larval Amblystoma in which the humerus had been completely removed. The cartilage of the new limb skeleton develops out of a blastema in which there are no cells of cartilage origin. This regeneration blastema is a composite structure made up of cells derived from a dedifferentiation of the injured tissues of the limb. The tissues which have been observed as contributing to the regeneration blastema are: muscles, especially the muscles of the shoulder; connective tissue of the sheath of the brachial nerve plexus; muscle connective tissue; and, to a certain extent, subcutaneous connective tissue. The new cartilage of the limb skeleton develops out of this composite blastema by means of a differentiation of cells in the central axis of the blastema.The amount of cartilage regenerated appears to depend on the mass of the blastema. When the blastema does not extend fully into the glenoid cavity of the scapula, the head of the developing humerus is deficient in size and structure. However, a complete limb skeleton is regenerated when the blastema does extend fully into the glenoid cavity.Since the new cartilage of the regenerated limb has no genetic continuity with the old limb skeleton, it would appear that the limb field exerts some kind of histogenetic determining action.
    Materialart: Digitale Medien
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  • 58
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 263-297 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Artemia salina, a very widely distributed species in North America, Europe and Asia, breeds freely and rapidly under laboratory conditions, living in all salinities from fresh water to almost saturated brine. Its soft exoskeleton permits of easy sectioning.The morphology and embryology of the segmentally arranged excretory glands - the antennal, mandibular and maxillary glands, are described. The antennal gland, consisting of extracellular end sac and intracellular excretory duct, is located in the second antenna and opens to the exterior on the lateroposterior face of the protopodite. It attains its maximum development by the sixth instar, degenerating by the tenth. The vestigial mandibular gland consists only of an end sac surrounding a schizocoele, and a rudimentary duct. The large maxillary gland in the adult consists of an end sac, an excretory duct of three circular coils, and a terminal duct opening to the exterior. The maxillary gland develops from a mass of mesenchyme cells in the maxillary segment of the nauplius, becoming fully differentiated by the sixth instar.The vestigial second maxilla has two bristles. It serves only as a terminus for the maxillary gland. A pair of small ganglia are accepted as internal evidence for the presence of a maxillular segment.The presence of three pair of schizocoeles in three consecutive segments is interpreted as evidence of homology with the Annelid coelome, with the possibility of further homologizing the excretory ducts with the segmental nephridia.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
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  • 59
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 503-521 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: In early embryonic stages of Passalus there are, in addition to the brain and suboesophageal ganglion, three thoracic and ten abdominal ganglia; one ganglion to each body segment. Before hatching the tenth, ninth and eighth abdominal ganglia coalesce. During the three larval instars the terminal ganglion remains in the sixth abdominal segment and only minor changes occur. By the end of the third day of pupal life the adult form of the nervous system is practically assumed. All abdominal ganglia are fused into a single, solid, elongated ganglionic mass. Connectives have disappeared between meso- and meta-thoracic and between metathoracic and abdominal ganglia; and with exception of the brain, sub-oesophageal and prothoracic ganglia, the entire ventral chain has come to lie in the mesothorax. The peripheral nerves still arise from the ganglia and ganglionic mass in their same relative positions and still supply the same segments in which they were originally located.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 60
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 599-607 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Analysis of measurements of the trunk region of the vertebral column and of the various segments of the wing and leg skeleton in sixty-four specimens (thirty-four males, thirty females) of Fulica americana shows that: The males average about 7% larger (longer) than females in all parts of the skeleton; the difference is uniform throughout the body. The coefficient of variability ranges from about 3.00 (humerus, et al.) to about 5.00 (hind toe). The correlation between lengths of parts is very high between different segments of the wing skeleton, or of the leg; it is somewhat less between homologous segments of the wing and leg; and it is still less between limbs and trunk. This decreasing order of correlation indicates an increasing order of independence of variability. The wing proportions in Fulica are those characteristic of the type of flight called flatterflug. The proportions of the leg are those of a bird moderately adapted for cursorial locomotion; the very long toes characterize a swimming bird.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 61
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Cyto-centrosomes containing centrioles but lacking asters originate de novo in great number throughout the ooplasm of Habrobracon eggs during the formation of the first maturation metaphase. These cyto-centrosomes apparently arise from accessory nuclei which are formed from granules extruded by the germinal vesicle. The accessory nuclei react negatively to the Feulgen nucleal test.Asters similar to those present in artificially parthenogenetic eggs appear around many of the cyto-centrosomes, thus forming cytasters. These are manifest only after the female pronucleus establishes an association with a cyto-centrosome, which thus becomes the nuclear centrosome.In the parthenogenetic egg the centriole of the nuclear centrosome is continuous from one cell generation to the next, whereas the centrioles of the cyto-centrosomes which are unassociated with nuclear material are not perpetuated and disappear during early cleavage.Concerning the origin of the first cleavage centrioles in fertilized eggs, evidence shows that in some ova it is entirely maternal, that is, from two cyto-centrosomes, one associated with the female pronucleus and occupying one pole of the first mitotic spindle, and the other associated with the male pronucleus and located at the opposite pole; while in other ova it is maternal-paternal; from two centrosomes, one the sperm centrosome which occupies one pole of the first cleavage spindle, and the other a cyto-centrosome associated with the female pronucleus and situated at the opposite pole.
    Materialart: Digitale Medien
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  • 62
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 243-261 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Collections of Campeloma rufum were made at all seasons of the year from the Salt Fork River at Homer Park, Illinois, for gross anatomical and histological studies. No males nor male reproductive cells were found, all individuals showing definite female structures. The gonad, found on the columellar surface of the digestive gland, shows ovarian cells. A U-shaped tube from the albumen gland to the uterus receives the oviduct near its proximal end. This duct leads into a glandular pocket, the shell gland, which in turn empties into the sac-like uterus. The uterus terminates near the edge of the mantle in a muscular vaginal tube. The previously undescribed kidney, a glandular, pyramidal organ, lies posterior and to the left of the upper end of the mantle cavity. The kidney possesses two orifices opening into the pericardium and ureter respectively. The ureter opens between the vagina and the anus. Intra-uterine young were observed during all seasons of the year varying progressively from small veliger to fully formed young. A later paper on oogenesis, will attempt to substantiate parthenogentic reproduction for C. rufum.
    Materialart: Digitale Medien
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  • 63
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A detailed study of Wright's polydactylous monster (produced by a semi-dominant lethal gene) indicates that it belongs to a general type found also in rare human cases. The diagnostic characteristics are: clubbed feet and approximately double the usual number of digits, embryonic posture, microphthalmia and enlargement of the diencephalon, and missing tibia and telescoped sternum; all organ systems in the body except the genital and circulatory are grossly abnormal. The defects appear to be produced by an arrest of morphogenesis and an alteration of relative growth rates. It is indicated that a controlling center of digit formation exists on the lateral (postaxial) side of the foot, that skeletal and dermal structures are controlled by it, but that muscles are differentiated according to the area of the limb in which they lie. The gene itself is not atavistic, although its effects in the heterozygote have that appearance.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
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  • 64
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 393-413 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The microscopical examination of the first haploid salamander to live through metamorphosis shows that the transformation to a terrestrial vertebrate was normal and practically completed at the time of its death. All the organs and structures that develop shortly before and during metamorphosis and are typical for the adult salamander, e.g., the integument, the pharyngeal derivatives, and various glands of special function, are present.The nuclei in all organs and tissues of the haploid animal are smaller than normal. This is indirect evidence of the uniformly haploid condition of the animal. The majority of the organs are smaller than in the control but contain a larger number of cells. In some glands, the reduced cell size has been completely compensated by the increase in cell number.
    Materialart: Digitale Medien
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  • 65
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 375-391 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: A study is made of the pancreatic islands in Rana clamitans, R. catesbiana, R. sylvatica and Hyla versicolor during various stages of development. The islands, which were first seen in the 8-mm. R. clamitans larvae, originate from the endodermal cells of the primitive pancreatic anlagen. Following early larval development in all of the species, new islands differentiate from the cells of the pancreatic ductules. During metamorphosis, much of the acinous tissue degenerates, but the islands persist. They become aggregated and the definitive islands are formed from the primary islands before the mature adult stage is reached.With the azure-eosin technique, two types of island cells were distinguishable before, or at the time of metamorphosis, in all of the anurans studied. They are designated as the red and blue types. The blue cells are considered the primitive or embryonic type, and may transform into the red type; or the red type may originate independently.
    Materialart: Digitale Medien
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  • 66
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 523-557 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Ovaries of bats, Myotis lucifugus lucifugus and M. grisescens, have been studied in all phases, except gestation, of the annual reproductive cycle. Oocytes arise in the germinal epithelium and grow with an orderly differentiation of the storage products of metabolism - chondriosomes, fat drops, and yolk vesicles. The evidence indicates that the zona pellucida is derived from the oocyte. Squamous cells of the primary follicle become cuboidal and then columnar as follicular growth begins (unilaminar secondary stage). The secondary follicle becomes multilaminar and in a very few cases gives rise to a tertiary follicle by antrum formation. Most growing follicles undergo retrogression by one of two methods. Degeneration of type I is common in multilaminar follicles and begins in the granulosa which is almost completely obliterated before the oocyte is affected. Spindles occur in some of these oocytes and fragmentation is common; phagocytes eliminate the contents of the zona. In type II, which is rare and has been found only in unilaminar secondary follicles, the oocyte degenerates, leaving an uninjured granulosa. Medullary cords are common embryonic vestiges in these ovaries; epithelial nodules are less frequent. Interstitial cells are very numerous in newborn bats, arise throughout life from the hypertrophied thecae internae of retrogressing follicles of type I, are phagocytized and, also, undergo hyaline degeneration, are hypertrophied in late pregnancy, and continue so during lactation.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
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  • 67
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Separation of the mantle from the visceral mass on the right side in deeply cupped species of oyster provides a shorter channel for egress of water from the right demibranchs. Correlated with this change is reduction in size of the right epibranchial chamber beneath the adductor together with backward displacement of the adductor itself. This water passage, designated the promyal chamber, develops during the first week after attachment of the oyster larva. The greatest displacement of the adductor and the largest promyal chamber occur in O. frons. The mantle border shows three reduplications of which the innermost, the pallial curtain, controls the amount and the place of entrance and egress of water. The importance of pallial curtains and promyal chamber to survival in turbid waters is discussed; oysters with the promyal chamber have invaded the river mouths, the flat oysters without this chamber have remained in the clear waters of high salinity near the sea. The bearing of these factors on the disappearance of fossil oysters is considered. It is proposed to relate to the genus Ostrea all flat, larviparous oysters which lack the promyal chamber and to raise the subgenus Gryphaea to generic rank to include all deeply cupped oviparous oysters with the promyal chamber. Anatomical and histological features of the pallium and branchial chambers are considered in detail.
    Zusätzliches Material: 21 Ill.
    Materialart: Digitale Medien
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  • 68
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 141-175 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: This paper is based on information derived from a sectioned skull of Cynariops robustus Broom, a prepared skull of Cynariops longiceps Olson, prepared and sectioned specimens of Captorhinus, Dimetrodon and various cynodonts, and the literature dealing with these forms.In the otic region, it is shown that the internal auditory meatus, the fallopian aqueduct and the semicircular canals change but little in the series from Captorhinus to the cynodonts. Certain structures, the fenestra ovalis, which becomes progressively smaller, the vestibule, which lies progressively more ventral to the floor of the brain case, the recessus lagenacochlea, which increases in size, and the prootic, which enlarges, show progressive change. The fenestra rotundum is discussed at length. It is absent in Captorhinus, just back of the fenestra ovalis in the Gorgonopsia and Dimetrodon, and confluent with the foramen jugularis in the Cynodontia.The length and relationships of the parasphenoid in the Gorgonopsia are offered as evidence supporting the theory of the homology of the reptilian parasphenoid and the mammalian vomer.The sphenethmoid complex in Cynariops is divided into two elements, a basal member, the presphenoid, and a dorsal member, identified as the orbitosphenoid but possibly incorporating a portion of ossified mesethmoid as well.The comparative studies point out certain basic trends of evolution in the Synapsida, and indicate the level of evolutionary development of the groups studied.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
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  • 69
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 323-349 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: In the Anablepidae, a family of viviparous Cyprinodont fishes, the mature eggs are fertilized in the ovarian follicles. The embryos are retained in the modified ovarian follicles until birth and are born when about 44 mm. in length. The embryos develop expanded yolk sacs which reach a maximal diameter of about 10. mm. The vitelline veins on the surface of the yolk sac develop rows of bead-like swellings, yolk sac bulbs, which serve to facilitate absorption of materials from the fluid of the follicle cavity. There is an extensive system of follicular villi upon the internal lining of the follicular capsule, the apparent function of which is to increase the vascular surface of the internal lining of the follicular capsule and to facilitate the interchange of materials between the blood of parent and fluid of the follicular cavity. The follicular villi and the yolk sac bulbs develop at the same time. These two adaptations for viviparity are apparently unique in this family of fishes.
    Materialart: Digitale Medien
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  • 70
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: Viviparity in the teleost fishes is most highly developed in the family Embiotocidae. In Cymatogaster aggregatus, a member of this family, the males are sexually mature at birth. Females born in June and July are inseminated soon after birth and carry the spermatozoa in the ovarian cavity until December when eggs are fertilized. Embryos are retained in the ovarian cavity till the following spring when they are born.The cells of the epithelium lining the ovarian cavity develop internal fluid reservoirs which reach their maximal stage in early gestation when there is an extensive sloughing of epithelial cells. The epithelium returns to its original condition in late gestation and later the cells undergo multiplication. The stroma becomes swollen and contains a large amount of fluid during early gestation and shrinks as the embryos become larger. Many of the eggs, failing to reach maturity at the time of fertilization, degenerate. Degeneration also takes place in numerous smaller ovocytes during gestation but some of them survive to grow during the next season.The cyclical changes in the ovarian tissue of Cymatogaster aggregatus are parallel to those which occur in the ovaries of the Goodeidae and the Jenynsiidae, two other families in which viviparity has been highly developed.
    Materialart: Digitale Medien
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  • 71
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal of Morphology 62 (1938), S. 445-501 
    ISSN: 0362-2525
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Medizin
    Notizen: The first mesoderm cells, and therefore the primitive streak, originate from the epiblast in an axial zone of the third quarter of the area pellucida.The primitive streak grows by epiblastic proliferation only, without any forward movement of the epiblast.Presumptive mesoderm cells invaginate during the existence of the streak.The endoderm plays no part in forming the mesoderm and head process.The epiblast cells lose their glycogen when invaginating through the primitive streak or node, to form the mesoderm or head process, both of which are free of glycogen.When invaginating, the epiblast cells show an increase of lipoids (probably sterols) which decrease as they become mesoderm cells, but are retained in the head process. The higher lipoid content is correlated (1) with the organizing effect of the primitive streak, node and head process; (2) with the behavior of Nile blue marks, which when reaching the streak, node or head process are retained and no longer follow the movements of the individual cells.The shortening of the primitive streak is effected by the approximation of the epiblast from either side, which begins at the cranial end of the streak and spreads caudally. There is no backward migration of the cells of the primitive node.The arrangement of the presumptive embryonic material in the epiblast at the end of the blastula stage is described.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
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  • 72
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 62 (1938) 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 73
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 62 (1938) 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 74
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
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  • 75
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 62 (1938), S. 497-506 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
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  • 76
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 70 (1938), S. 331-349 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 7 Tab.
    Materialart: Digitale Medien
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  • 77
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 70 (1938), S. 371-387 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 18 Ill.
    Materialart: Digitale Medien
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  • 78
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 243-247 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 79
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 265-276 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
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  • 80
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 313-318 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 81
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 349-361 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
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  • 82
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 83
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 27-32 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
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  • 84
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 85
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 1-45 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 86
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 125-131 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
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  • 87
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 131-136 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 88
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 181-193 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 89
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 249-263 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 90
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938) 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 91
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 4 Tab.
    Materialart: Digitale Medien
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  • 92
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 313-331 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 11 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 93
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 387-394 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 94
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 71 (1938), S. 503-508 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 95
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 72 (1938), S. 491-501 
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 1 Tab.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 96
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 63 (1938) 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 97
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 63 (1938), S. 101-159 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 4 Tab.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 98
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 63 (1938), S. 161-219 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 28 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 99
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 63 (1938), S. 273-295 
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 100
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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