ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The isolation, characterisation and chemical investigation of the cardiac glycosides of the dried leaves of Isoplexis isabelliana (WEBB) MASF. are described. 7 glucosides B, D, E, J (monoside), K, M, and 1 (monoside) could be obtained in homogenous form, 3 others were mixtures (“A” = A1 + A2, “C” = C1 + C2, and “G” = G + K). The substances B (gluco-evatromonoside), D (cheiroside A), E (digitoxigenin-glucosido-6-deoxyglucoside), J (digitoxigenin glucoside), and M (digitalinum verum) could be identified with known substances. The new glycosides are derived from 3 genins: digitoxigenin, uzarigenin, and xysmalogenin, which are directly bound to one of the following sugars: 6-deoxyglucose, 2-O-acetyl-6-deoxy-D-glucose, 2,6-dideoxy-D-arabinohexose (= D-canarose), and 2,6-dideoxy-D-ribohexose (= D-digitoxose), terminated by a glucose unit. -Canarobiose, a new crystalline disaccharide of D-glucose and D-canarose, has also been obtained. -Apart from these cardiac glycosides 3 C21-steroids have been isolated (in addition to the 2 known genins γ-digiprogenin and purpnigenin), and their structures elucidated. The presence of 2 sapogenins has been detected.
Zusätzliches Material:
4 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19670500516
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