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  • 11
    Digitale Medien
    Digitale Medien
    Anti-keratin monoclonal antibodies: production, specificities and applications (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 10 (1983), S. 0 
    Details
    ISSN: 1600-0560
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0560.1983.tb01504.x
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  • 12
    Digitale Medien
    Digitale Medien
    Monilethrix: an ultrastructural study (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    Details
    ISSN: 1600-0560
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Characlcristic moniliform hairs of monilcthrix were ultrastructurally examined. By scanning electron microscope, nodes and internodes were seen alternating on the affected hair; the nodes were normal in apparance and thickness, while the internodes were thin and showed ridges and flutes. By transmission electron microscope, the cross sections of the internodes revealed wrinkling of the hair coticular cells and a reduced number of the cortical cells. Cross sections of the cortical cells per se showed a similar size and a normal keratin pattern in both nodes and internodes, compared with those of control hairs from normal individuals. From these findings, the internodes seemed to be the pathological portions of the monilifonn hair, and such abnormal thinning of hair shaft might tie caused by a periodical dysfunction of the hair matrix, especially in the hair cortex.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0560.1984.tb00412.x
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  • 13
    Digitale Medien
    Digitale Medien
    Colloid and elastic fibre: ultrastructural study on the histogenesis of colloid milium (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 10 (1983), S. 0 
    Details
    ISSN: 1600-0560
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Tissues peripheral to well-developed papules of colloid milium were chosen for biopsy and electron microscopy examination. Evidence was presented that colloid is derived from elastic fibres through sequential degenerative changes. In the upper to middle dermis of the peripheral tissue, a number of abnormal masses in the vicinity of small colloid depositions were observed. Ultrastructurally, those abnormal masses were degenerating elastic fibres in which “electron-dense layers” of normal elastic fibre increased in amount, although their electron density diminished. Electron-light layers were gradually diminished in quantity. Degenerated elastic fibres finally became granulo-fibrillar and were indistinguishable from colloid. Many fibrils which closely resembled 10 nm tubular microfibrils of normal elastic fibre were observed in the granulo-fibrillar substance. Since one stage of the degeneration of elastic fibre which eventually leads to the formation of colloid milium was very similar to that of actinic elastosis, a direct role of sunlight in the formation of colloid milium is suggested.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0560.1983.tb01484.x
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  • 14
    Digitale Medien
    Digitale Medien
    Large melanoacanthomas: a report of five cases (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    Details
    ISSN: 1600-0560
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Five patients with mclanoacanthonia are reported. The skin lesions consisted of a single, round plaque measuring several centimeters in diameter. Histologic findings were characterized by formation within an acanthotic epidermis, of many islands of small basaloid cells and highly dendritic melanocytes. Electron microscopic examination of one lesion revealed a disturbance of melanin transfer from the highly dendritic melanocytes to the neighboring keratinoeytes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0560.1984.tb00383.x
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  • 15
    Digitale Medien
    Digitale Medien
    Different responses of the isolated canine coronary artery superfused with blood or Krebs-Henseleit solution (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 156-158 
    Details
    ISSN: 1432-1912
    Schlagwort(e): Canine coronary artery ; Superfusion media ; Nifedipine ; Ca2+-channels
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Responses of ring segments of the isolated canine coronary artery superfused with arterial blood from a donor dog were compared with responses of segments superfused with Krebs-Henseleit (K-H) solution. KCl (1–30 mg) caused contraction in a dose-dependent manner both in K-H solution- and in blood-superfused preparation. However, CaCl2 (1–100 mg) and nifedipine (0.1–30 μg) contracted and relaxed, respectively, only blood-superfused preparation but not K-H solution-superfused one. These results show that even in the same region of the coronary artery, different superfusates result in different responses to contracting or relaxing agents. This difference may be explained by the idea that Ca2+-channels are activated and endow basal tension in blood-superfused preparations, but not in K-H solution-superfused ones.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00500911
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  • 16
    Digitale Medien
    Digitale Medien
    Effect of cordycepin on the replication of western equine encephalitis virus (1976)
    Springer
    Archives of virology 52 (1976), S. 341-345 
    Details
    ISSN: 1432-8798
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Cordycepin (3′-deoxyadenosine) inhibited viral RNA synthesis in the replication of western equine encephalitis virus, thereby causing a reduction of virus production. The rate of inhibition of viral RNA synthesis was dependent on drug concentration and the period of treatment with the drug. These results suggest that the virus RNA synthesizing system is sensitive to the drug.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01315623
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  • 17
    Digitale Medien
    Digitale Medien
    Immunohistochemical demonstration of the localization of corticotropin releasing factor-containing neurons in the hypothalamus of mammals including primates (1982)
    Springer
    Anatomy and embryology 165 (1982), S. 303-313 
    Details
    ISSN: 1432-0568
    Schlagwort(e): CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Mammals
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The presence of the CRF-containing neurons in the hypothalamus was investigated in four different species (cats, dogs, pigs, and monkeys) by the peroxidase-antiperoxidase technique using specific anti-serum to CRF. In all animals examined, CRF-containing perikarya were found mainly in the paraventricular and supraoptic nuclei, and a small number of the immunoreactive cells were observed in the accessory supraoptic nucleus and the lateral hypothalamic area. The size of the CRF-containing perikarya ranged from 20–35 μm in diameter. These findings suggest that the magnocellular paraventricular and supraoptic nuclei are the center not only of the classical neurosecretory system for the production of the posterior lobe hormones, but also that of the CRF neuronal system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00305569
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  • 18
    Digitale Medien
    Digitale Medien
    Occurrence of tetrodotoxin in the starfishAstropecten latespinosus (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 1395-1396 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Astropecten latespinosus ; starfish ; tetrodotoxin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary A toxin causing paralysis was detected in the starfishAstropecten latespinosus. The toxin was purified by a method consisting of charcoal treatment and chromatography on CM-Sephadex C-25 and Bio-Rex 70. The toxin was identified as tetrodotoxin by its behavior in thin-layer chromatography and electrophoresis and its1H-NMR spectrum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01951908
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  • 19
    Digitale Medien
    Digitale Medien
    Inhibition of brain enolases by acrylamide and its related compounds in vitro, and the structure-activity relationship (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 971-972 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat brain ; Enolase ; acrylamide ; acrylamide derivatives ; neurotoxicity ; structure-activity relationship
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Acrylamide and its related compounds inhibited brain enolases in vitro independently of their neurotoxicity. The inhibitory potency was a function of the binding constants of the compounds for phenylalanine. The binding constant for tryptophan was higher in neurotoxic compounds than in non-neurotoxic ones.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01946464
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  • 20
    Digitale Medien
    Digitale Medien
    Immunohistochemical demonstration of corticotropin releasing factor containing nerve fibers in the median eminence of the rat and monkey (1982)
    Springer
    Histochemistry and cell biology 76 (1982), S. 15-19 
    Details
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary By means of the peroxidase-antiperoxidase technique, in conjunction with a specific anti-CRF serum, it was shown that a large number of immunoreactive nerve fibers were demonstrable on the capillary loops of the hypophysial portal vessels in the external layer of the median eminence of the rat and monkey, particularly in its medial part. This result confirms the radioimmunological determination of CRF immunoreactivity in the median eminence.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00493281
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