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  • 2000-2004
  • 1970-1974  (13)
  • 1972  (7)
  • 1971  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1971)
    Springer
    Journal of molecular medicine 49 (1971), S. 1301-1304 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01733089
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Zur Bestimmung der Methionin-Synthetase in menschlichen Geweben und ihrer biologischen Bedeutung (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 985-985 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Methionin-Synthetase ist ein Schlüsselenzym in der Synthese von Nucleoproteiden. Ein einfaches Verfahren für die routinemäßige Bestimmung wurde in unseren Arbeitskreisen entwickelt. Die Kontrolle dieses Enzyms läßt wichtige Ergebnisse, besonders für die Diagnose und Therapie bösartiger Erkrankungen, erwarten.
    Notes: Summary Methionin synthetase is a key enzyme in nucleoprotein synthesis. A simple method for its routine estimation was developed. Sequential determinations may become an important parameter in cell metabolism, especially in relation to diagnostics and therapy of neoplastic diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01486991
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Demonstration of adenosin 3′,5′-monophosphate dependent protein-phosphokinase in human platelets (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 1114-1115 
    Details
    ISSN: 1432-1440
    Keywords: Platelets ; Cyclic AMP ; Protein-phosphokinases ; Blutplättchen (Mensch) ; c-AMP ; Protein-Phosphokinase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In menschlichen Blutplättchen wurde eine Enzymreaktion gefunden, die die Eigenschaften typischer Proteinkinasen anderer Zellen und Gewebe zeigt: Phosphorylation basischer Proteine (Histon) in Serin- und Threoninresten, Magnesiumabhängigkeit und Stimulation durch Adenosin 3′,5′-monophosphat. Dieses Enzym könnte ein wichtiges Bindeglied zwischen der intracellulären c-AMP-Konzentration und der Plättchen-Funktion darstellen.
    Notes: Summary An enzyme reaction in human platelets is demonstrated which possesses the properties of protein-phosphokinases isolated from other cells: phosphorylation of basic proteins in phosphoserine and -threonine linkages, magnesium dependency and stimulation by adenosine 3′,5′-monophosphate. It is suggested that this enzyme might be responsible for the expression of the cAMP effects on the platelets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01486857
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Verhandlungen ärztlicher Gesellschaften (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 889-892 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01488949
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Das Proteinmuster der Ductus thoracicus-Lymphe von Normalpersonen und Patienten mit Lebercirrhose (1972)
    Springer
    Journal of molecular medicine 50 (1972), S. 86-91 
    Details
    ISSN: 1432-1440
    Keywords: Lymph ; Proteins ; Immunoglobulins ; Isoenzymes ; Peptides ; Lymphe ; Proteine ; Immunglobuline ; Isoenzyme ; Peptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Proteine aus Ductus thoracicus-Lymphe von 7 Patienten mit Lebercirrhose wurden mit Blutseren derselben Patienten sowie mit Lymph- und Blutseren von Normalpersonen nach Konzentration, elektrophoretischem Verhalten im Polyacrylamidgel, immunologischen Eigenschaften und Enzymgehalt verglichen. Auffallend war in den Lymphseren ein relativ geringer IgM-Gehalt, ein teilweise erhöhter IgA-Gehalt, eine hohe Albuminkonzentration, ein lebertypisches LDH-Isoenzymmuster, in 2 Lymphseren das Vorkommen eines lebereigenen Proteins und in einigen pathologischen Lymphseren das Auftreten eines Glykopeptids in hoher Konzentration.
    Notes: Summary The proteins of the thoracic duct lymph and blood serum from seven patients with liver cirrhosis and from normal persons were characterized by protein determination, electrophoresis on polyacrylamid gel, as well as by immunological and enzymatic methods. Differences between lymph and blood sera were observed. The lymph sera showed a low IgM content, a partially elevated IgA content, high albumin concentration, and altered LDH-isoenzyme pattern. In some lymph sera high concentrations of soluble protein from the liver and a glycopeptide were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01484815
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  • 6
    Electronic Resource
    Electronic Resource
    Isolation of the lymphoagglutinating fractions of phytohaemagglutinin (PHA) from phaseolus vulgaris and characterization of their biological properties (1971)
    Springer
    Journal of molecular medicine 49 (1971), S. 286-288 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung PHA-P wurde durch Ionenaustausch-chromatographie, Absorption der Fraktionen an Schweine-erythrocyten und isoelektrische Focussierung fraktioniert. Es fanden sich 2 aktive Fraktionen. Beide Fraktionen hatton lymphagglutinierende, mitogene und Cytoaggression induzierende Aktivität. Trotz verschiedener isoelektrischer Punkte waren die biologischen Eigenschaften der beiden Fraktionen qualitativ gleich. Es war nicht möglich, einzelne der an Lymphocyten auslösbaren Reaktionen verschiedenen Fraktionen zuzuordnen. In unserer Präparation stand die biologische Aktivität quantitativ in Relation zum Proteingehalt der Fraktionen. Auch war die biologische Wirkung an Protein geknüpft. Allerdings fehlen bisher Versuche, die biologische Aktivität vom Protein zu trennen. Wir sind aufgrund anderer Versuche davon überzeugt, daß die Bindungsstellen des aktiven Moleküls mehr durch Kohlenhydrate als durch Proteine repräsentiert werden.
    Notes: Summary Phytohaemagglutinin (PHA-P) was separated by ion exchange chromatography, absorption procedures, and isoelectric focusing. Two active fractions were obtained. One of them was homogenous by physico-chemical characterization. Both fractions showed lymphoagglutinating, mitogenic, and cytoaggression-inducing activity. In spite of varying isoelectric points, the biological properties were qualitatively identical. It was not possible to associate single properties to different fractions. In our preparation, the biological activity was related to protein and to the protein content of the fractions. From other experimental data, we think that the binding sites of the active molecule are represented by carbohydrates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01485435
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  • 7
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    Making Sense out of the Terminology of the New Social Studie s (1972)
    Philadelphia : Periodicals Archive Online (PAO)
    Social studies. 63:4 (1972:Apr.) 147 
    Details
    ISSN: 0037-7996
    Topics: History
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3111-1972-063-04-000002
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  • 8
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1971)
    Springer
    Annals of hematology 22 (1971), S. 351-355 
    Details
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01632024
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1971)
    Springer
    Annals of hematology 23 (1971), S. 42-46 
    Details
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01815134
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Dynamic pressure-flow curves in the autoregulating kidney vasculature of conscious dogs (1972)
    Springer
    Pflügers Archiv 335 (1972), S. 29-45 
    Details
    ISSN: 1432-2013
    Keywords: Blood Flow Velocity ; Renal Artery ; Blood Pressure ; Vessel Distensibility ; Autoregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In three healthy conscious dogs blood pressure was measured in the abdominal aorta with an implanted miniature transducer. Flow velocity in the left renal artery was recorded by an electromagnetic flowmeter. An appropriate distance between the transducer sites compensated the time-lag introduced by the flowmeter system and allowed records with a negligable foot to foot phase shift between the flow- and the pressure pulse. Pressure-flow curves (I.-P. curves) were obtained recording flow versus pressure beat by beat on an oscilloscope. Electrical stimulation of the right cervical vagus nerve produced I.-P.-curves, which decayed in less than 3 sec down to a blood pressure of 25 mm Hg (dynamic I.-P.-curve). Static I.-P.-curves were recorded by reducing blood pressure within 1 to 2 min to the same pressure level. The following results were obtained: A unique dynamic I.-P.-curve, which follows the power functionI=a·P n exists for each level of arterial mean pressure i.e. “myogenic” vascular tone. An increase of arterial mean pressure (i.e. “myogenic” vascular tone) decreases the exponentn and increases the coefficienta of the power function. The static I. P.-curve, which runs parallel to the pressure axis above 90 mm Hg is actually composed of a family of different dynamic I.-P.-curves. The kidney resistance vessels are rather distensible. The pressure-dependent increase of “myogenic” vascular tone, which developes at perfusion pressures above 55 mm Hg, decreases the vessel distensibility. A change of mean perfusion pressure causes the kidney resistance vessels to shift from one to another dynamic I.-P.-curve without altering mean blood flow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00586933
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