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  • 1985-1989
  • 1980-1984  (195)
  • 1984  (195)
  • Chemical Engineering  (106)
  • Engineering  (62)
  • Rat  (27)
  • Magnetic resonance imaging
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 170 (1984), S. 79-85 
    ISSN: 1432-0568
    Keywords: Perineuronal net ; Astrocytes ; Fastigial nucleus ; Cerebellum ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The morphological study of the rat fastigial nucleus with the Golgi-Rio Hortega method showed the presence of glial perineuronal nets surrounding the large neurons, but not the small ones. This perineuronal net appeared as a mesh of tenuous glial processes which covers the neuronal perikarya and proximal dendrites. The small alveolate compartments in this mesh seem to correspond to the holes for the synaptic boutons. Our results also indicate that the perineuronal net is derived from interneuronal protoplasmic and velate astrocytes. Using camera lucida drawings of this perineuronal net we have made a quantitative estimation of the size and density of synaptic boutons on these large neurons. The average numerical density of synaptic boutons was about 19 per 100 μm2 of the neuronal surface, the mean area of the synaptic holes being 2.5 μm2. Furthermore, the quantitative data evidence that about 52.5% of the neuronal surface is presumably occupied by synaptic boutons whereas the remaining 47.5% is covered by the glial processes of the perineuronal net. Semithin sections prepared from thick Golgi sections were used for the cytological study of the neurons surrounded by this glial pericellular network. The possible functional significance of the perineuronal net in the regulation of synaptic transmission in the fastigial cerebellar nucleus is briefly discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 20 (1984), S. 1952-1952 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 30 (1984), S. 50-55 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Intermediate phases and reactions occurring on decomposing diammonium hydrogen phosphate, ammonium para molybdate, sodium tungstate dihydrate and ammonium meta vanadate were established by thermal analysis and X-ray examination.These salts promote fabric degradation at low temperatures but are effective at high temperatures. Diammonium hydrogen phosphate produced maximum amount of gases, absorbed the highest amount of heat and gave the highest fire retardation above 350°C.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 24 (1984), S. 287-290 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Inverse gas chromatography (IGC) has been used to investigate thermodynamic miscibility of a molten poly(ethylene oxide) (PEO)/poly(methyl methacrylate) (PMMA) blend. Toluene, benzene, and chloroform have been employed as probes in pure and mixed stationary phases of these polymers. Experimental measurements have been taken over a narrow range of temperatures because of the high PMMA glass transition temperature as well as the degradation of the PEO. The interaction parameter χ23 determined at 150°C is slightly negative and dependent on the interacting probe, as has been also noted in previous chromatographic studies on polymer-polymer miscibility. The last section is devoted to a model calculation, using Flory's equation of state theory. Different χ23-concentration curves have been simulated, with the interaction energy parameter X23 as an adjustable parameter.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 24 (1984), S. 936-940 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Barium complexes were embedded in plasticized poly(vinyl chloride) (PVC) membranes. Effects of these metallic complexes were followed as a function temperature and strain rate. It was found that both the elastic modulus and yield stress decrease with barium content. This behavior is attributed to a lack of uniform structure and the existence of irregularities and voids in the bulk membranes. Another factor which may reduce the tensile strength is te internal and interfacial residual stresses developed at the metal-matrix interface. These internal stresses and the structural nonuniformity influence the electrical conduction mechanism and performance of the PVC matrix ion-selective electrodes during aging. Also, it was observed that the yield stress of these membranes has a strain rate and temperature dependence.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 24 (1984), S. 608-611 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A commercial polyarylate (PAr), a copolyester of Bisphenol-A with 50 percent terephthalate-50 percent isophthalate, has been characterized by means of a combination of gel permeation chromatography and viscometry. It has been studied as first component of a series of polymer blends. The presence of either one glass transition temperature (Tg) or two has been used as a criterion to determine the miscibility of each blend. In some cases, the possible incidence of transesterification reactions has been considered.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2072
    Keywords: (+)-Amphetamine ; Self-administration ; Dopaminergic neurons ; Acquisition ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of 6-OHDA lesions of the dopaminergic mesocorticolimbic cell bodies on intravenous (+)-amphetamine self-administration in the rat was assessed. An acquisition paradigm was used in which the rat had to discriminate between an active and an inactive lever. Each press on the active lever delivered 7.5 μg/kg (+)-amphetamine. The lesioned animals acquired this discrimination faster and hence self-administered a larger amount of drug. Thus dysfunction of dopaminergic neurons can induce an enhanced vulnerability to drugs which may be abused by humans.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-2072
    Keywords: Haloperidol ; Sulpiride ; Striatum ; Supersensitivity ; Dopamine receptors ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Administration of haloperidol (1.4–1.6 mg/kg/day) for up to 12 months or sulpiride (102–109 mg/kg/day) for between 6 and 12 months increased the frequency of purposeless chewing jaw movements in rats. N,n-propylnorapomorphine (NPA) (0.25–2.0 mg/kg SC) did not induce hypoactivity in haloperidol-treated rats at any time; sulpiride treatment for 9 and 12 months caused a reduction in the ability of NPA to induce hypoactivity. Haloperidol, but not sulpiride, treatment enduringly inhibited low dose apomorphine effects (0.125 mg/kg SC). After 12 months, sterotypy induced by high doses of apomorphine (0.5–1.0 mg/kg) was exaggerated in haloperidol-, but not sulpiride-treated rats. Bmax for specific striatal 3H-spiperone binding was increased by haloperidol, but not sulpiride, treatment throughout the study. Bmax for 3H-NPA binding was elevated only after 12 months of both haloperidol and sulpiride treatment. Bmax for 3H-piflutixol binding was not alfered by chronic haloperidol or sulpiride treatment. Striatal dopamine-stimulated adenylate cyclase activity was inhibited for the 1st month of haloperidol treatment, thereafter returning to control levels; dopamine stimulation was increased after 12 months of sulpiride treatment. Striatal acetylcholine content was increased after 3 and 12 months of treatment with haloperidol, but was not affected by sulpiride. Chronic administration of sulpiride does not induce identical changes in striatal dopamine function to those caused by haloperidol.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2072
    Keywords: Δ 1-Tetrahydrocannabinol (Δ 1-THC) ; Cannabidiol (CBD) ; Social behavior ; Social interactions ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A low and a high dose of Δ 1-Tetrahydrocannabinol (Δ 1-THC) and of cannabidiol (CBD) were IP injected in rats that had been isolated for 7 days. Forty-five minutes after injection, the rats were tested for social interactions with non-isolated, untreated test partners in dyadic encounters under standardized conditions. Different aspects of social behavior were analyzed. The high dose of Δ 1-THC (10 mg/kg) prevented nearly all social interactions. The low dose of Δ 1-THC (1 mg/kg) exerted selective and specific effects on social interactions. Social contact behavior, including crawl over/mounting, and social grooming, and aggressive behavior, including fighting, kicking, and biting, were markedly decreased, whereas social exploratory behavior (exploration of the partner and anogeniaal investigation) and the behavioral item, approach/follow, were hardly affected by Δ 1-THC treatment. Both doses of CBD (2 and 20 mg/kg) failed to change the various aspects of social interaction. It is postulated that the effects of Δ 1-THC on close and intimate contact behavior of rats may contribute to the understanding of marihuana taking in humans.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0738
    Keywords: 203Hg ; DMPS ; Age ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effectiveness of DMPS (sodium 2,3-dimercaptopropane-1-sulfonate) in reducing inorganic mercury retention was studied in 2-, 6-, and 28-week-old albino rats. 203Hg was administered IP. The chelating agent DMPS was administered by IP injection at a dose of 250 μmol/kg body weight three times, 1 day after 203Hg administration and at 24 h intervals thereafter. The whole body retention determined 1, 2, 3, and 6 days after 203Hg administration showed that DMPS decreased the body retention of mercury in all age groups, being about twice as effective in adult compared to suckling rats. The reduced effectiveness was due to the reduced efficacy of DMPS in reducing kidney retention in young animals. In other organs the effectiveness of DMPS was not age dependent. These and previous results obtained with different chelating agents and other metals indicate that age might be an important factor in chelation therapy in general.
    Type of Medium: Electronic Resource
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