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  • 1
    Electronic Resource
    Electronic Resource
    The energy component analyzer and spectrum analysis of end-loss ions in a tandem mirror (1991)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 62 (1991), S. 899-905 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Features of the electrostatic energy analyzer of a cylindrical type are described with the aim of measuring the end-loss ions in the tandem mirror GAMMA 10. The analyzer provides us with information about ion density distributions in a loss-cone region of velocity space as well as plug potential in the tandem mirror. Application of the analyzer to the tandem mirror experiments and the energy spectrum analysis are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1142027
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  • 2
    Electronic Resource
    Electronic Resource
    Electron-Beam Epitaxy and Superdiffusion in Alloy Semiconductors by Electron-Beam Irradiation (1991)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 38-41 (Jan. 1991), p. 1193-1198 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/05/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.38-41.1193.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemistry of leukotriene C4 in experimental cerebral vasospasm (1991)
    Springer
    Acta neuropathologica 81 (1991), S. 401-407 
    Details
    ISSN: 1432-0533
    Keywords: Leukotriene C4 ; Basilar artery ; Neutrophils ; Macrophages ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experimental cerebral vasospasm was produced in a “two-hemorrhage” canine model and examined by immunohistochemistry for leukotriene C4 (LTC4). The immunostain for LTC4 showed a strong positivity in intima and adventitia and a scattered reaction in media of normal basilar artery. The immunoreactivity after subarachnoid hemorrhage (SAH) was little changed in intima and media. Inflammatory cells which were characterized histochemically as neutrophils and macrophages, were shown to infiltrate from the adventitia of basilar artery to the periphery of blood clot after SAH and were markedly immunoreactive for LTC4. Also the neutrophils increased in number with the lapse of time after SAH. Thus, it would be reasonable to conclude that the LTC4 responsible for the development of vasospasm would most likely be produced from the infiltrating neutrophils and macrophages. In addition, neurons in hypothalamus, median eminence, and pons, as well as ependymal and arachnoid cells were immunoreactive for LTC4 both in the control and after SAH, whereas astrocytes and oligodendrocytes were not immunoreactive for LTC4 in either case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293461
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  • 4
    Electronic Resource
    Electronic Resource
    Low-dose aclarubicin in blastic transformation of essential thrombocythemia (1991)
    Springer
    Annals of hematology 62 (1991), S. 194-195 
    Details
    ISSN: 1432-0584
    Keywords: Low-dose aclarubicin ; Essential thrombocythemia ; Blastic transformation ; Myelofibrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We attempted treatment with low-dose aclarubicin (ACR), a new anthracycline, in a 66-year-old man with blastic transformation of essential thrombocythemia (ET). Two courses of ACR (20 mg/day x 7 days) were given intravenously. He showed a good response to this therapy without severe side effects. He has since maintained a state of prolonged remission. These observations indicate that low-dose ACR may be beneficial for management of the blastic transformation of ET.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01703149
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  • 5
    Electronic Resource
    Electronic Resource
    Production of islet cell antibodies from Epstein-Barr virus-transformed peripheral blood lymphocytes in Type 1 (insulin-dependent) diabetic patients (1991)
    Springer
    Diabetologia 34 (1991), S. 511-514 
    Details
    ISSN: 1432-0428
    Keywords: Islet cell antibodies ; Type 1 (insulin-dependent) diabetes ; Epstein-Barr virus ; peripheral blood lymphocytes ; transformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Islet cell antibodies are usually detected in the sera of almost all Type 1 (insulin-dependent) diabetic patients within several months after onset of the disease. The antibodies then disappear quite early during the course of the disease. The present study was undertaken to detect islet cell antibody-producing clones in peripheral blood lymphocytes of Type 1 diabetic patients whose islet cell antibodies could not be detected in sera. Epstein-Barr virus-transformed lymphocytes were employed to enhance the production of antibodies and to detect the clones from peripheral blood lymphocytes. Peripheral blood lymphocytes were obtained from 40 islet cell antibody-negative Type 1 diabetic patients, 10 antibody-positive Type 1 diabetic patients, 30 Type 2 (non-insulin-dependent) diabetic patients and 40 normal control subjects. Epstein-Barr virus-transformed lymphocytes were cultured for 4 weeks and the culture supernatants were used for assay of islet cell antibodies. Islet cell antibody assays were performed by immunohistochemical methods using peroxidase-labelled protein A for IgG antibodies, peroxidase-labelled anti-human IgM antibodies for IgM antibodies and fresh frozen human pancreatic tissue. IgG-islet cell antibodies were detected in 26 islet cell antibody-negative patients (65%), eight antibody-positive patients (80%) and one Type 2 diabetic patient (3%) in the culture supernatants. Islet cell antibodies in the supernatants could not be detected in any of the control subjects. IgM-islet cell antibodies could not be detected in any of the patients or control subjects. These findings indicate that islet cell antibody-producing clones exist in peripheral blood lymphocytes from Type 1 diabetic patients whose islet cell antibodies cannot be detected in their sera and IgG-islet cell antibodies might be a specific characteristic of Type 1 diabetes. The detection of islet cell antibodies from Epstein-Barr virus-transformed lymphocytes may be useful in examining the role of autoimmune mechanisms in the development of disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00403288
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  • 6
    Electronic Resource
    Electronic Resource
    Involvement of cytoplasmic pH in the production of ethylene, a potent inducer of sexual development inDictyostelium mucoroides (1991)
    Springer
    Protoplasma 160 (1991), S. 72-76 
    Details
    ISSN: 1615-6102
    Keywords: Dictyostelium mucoroides ; Cellular slime mold ; Cytoplasmic pH ; Ethylene ; Cyclic AMP ; Sexual development ; Macrocyst ; Sorocarp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Dictyostelium mucoroides-7 (Dm 7) and a mutant MF 1 derived from it exhibit two developmental pathways: sorocarp formation occurs during the asexual process, and macrocyst formation during the sexual cycle. The two developmental pathways are mainly regulated by two chemical substances: 3′,5′-cyclic adenosine monophosphate (cAMP) and ethylene. Recently, we have demonstrated that cytoplasmic pH (pHi) has a critical role for the choice of developmental pathways, higher pHi being favourable to macrocyst formation. Thereupon, attention was riveted to the relation of pHi to biosynthesis of cAMP and ethylene. Effect of pHi on the production and release of ethylene, a potent inducer of macrocyst formation, was examined, using the two facing culture method. The result showed that lowered pHi inhibits ethylene production, thus resulting in a failure of cells to form macrocysts. The accumulation of cAMP, an inhibitor of macrocyst formation, was found to vary depending on extracellular pH (pHo), but diethylstilbestrol (DES) that is a proton pump inhibitor and also an inhibitor of macrocyst formation had no significant effect on the accumulation. Taken together these results indicate that higher pHi may induce macrocyst formation through enhancement of ethylene production rather than inhibition of cAMP synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01539958
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  • 7
    Electronic Resource
    Electronic Resource
    Time-resolved X-ray diffraction studies on stretch-activated insect flight muscle (1991)
    Springer
    Journal of muscle research and cell motility 12 (1991), S. 208-215 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The specific feature of stretch activation of the indirect flight muscle of the tropical waterbugLethocerus was used to correlate mechanical and structural aspects of muscle contraction. The time courses of the changes in intensities of the strongest equatorial reflections, the (10) and (20) and of the first meridional reflection at 14.5 nm−1 were monitored using synchrotron radiation as a high intensity X-ray source. The ratio of the intensities of the equatorial reflections, (I20/I10), which reflects the mass distribution within the filament lattice array, increases by about 10% relative to the Ca2+-activated level when a rapid stretch is imposed, compared with a 200% change seen when fibres change from the relaxed to the rigor state, while the spacing of the lattice planes decreases by about 1%. The intensity of the first meridional reflection at 14.5 nm−1 decreases by about 35% during stretch activation with a slightly faster time course than the delayed tension increase. The results suggest that the average structure of cycling crossbridges is different from that present in the rigor state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01774040
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  • 8
    Electronic Resource
    Electronic Resource
    Separation of water-ethanol by pervaporation through polyion complex composite membranePaper presented at 3rd International Conference on Pervaporation Processes in the Chemical Industry, September 1922, Nancy, France. (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 42 (1991), S. 3229-3239 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: For the purpose of separating alcohol-water mixtures by the use of the pervaporation technique, new composite membranes composed of polyion complexes (PIC) as a separating layer were developed. The polyion complex structure, consisting of polyacrylic acid (PAA) and polycation, provided excellent permeation rate and selectivity. Among the polycations, ionenes, which have quaternary ammonium groups in the backbone chain, were effective in giving membranes of higher permselectivities. High selectivity of PIC membranes was observed at high ethanol concentration regions in the feed mixture. For the azeotropic mixture of water/ethanol (95 wt % EtOH) at 60°C, the PAA-based PIC membrane had the following separation properties: separation factor ∼ 3,500 and permeation rate ∼ 1.6 kg/m2 h.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1991.070421216
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