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  • 1
    Digitale Medien
    Digitale Medien
    Heavy doping effects in the diffusion of group IV and V impurities in silicon (1993)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 73 (1993), S. 691-698 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Studies of the diffusion of Ge, Sn, As, and Sb in Si at high donor concentrations provided by phosphorous doping have been performed. It is found that for donor concentrations, CD below ∼2×1020 cm−3, the diffusivity depends linearly on CD; for doping concentrations above ∼2×1020 cm−3, however, the diffusivity increases dramatically with increasing donor concentrations. This behavior has been successfully modeled within the vacancy–percolation model, and it is concluded that collective phenomena play a significant role at high donor concentrations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.353324
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  • 2
    Digitale Medien
    Digitale Medien
    Diffusion of ion-implanted Sn and Sb in heavily doped n-type silicon (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 755-757 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: The diffusion of ion-implanted Sn and Sb in silicon single crystals during rapid thermal annealing at 1000 and 1050 °C has been studied as a function of P donor concentration. For extrinsic/intrinsic carrier concentration ratios (n/ni )≥20, almost identical, extremely large diffusion coefficients are found for both impurities. The diffusion coefficients exhibit approximately an (n/ni )4 dependence. The onset of this dependence is accompanied by the appearance of a new defect-complex type containing Sb or Sn, respectively.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.99823
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  • 3
    Digitale Medien
    Digitale Medien
    Properties of sputtered superconducting films of Bi2Sr2CaCu2Ox made by low-temperature in situ growth (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 2135-2137 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Superconducting films of Bi2Sr2CaCu2Ox have been fabricated on single-crystal MgO substrates by a low-temperature in situ process. Using a substrate temperature Ts≈645 °C, metallic films with a superconducting onset of 90–100 K and an extrapolated Tc0=56 K have been obtained. X-ray diffraction shows the films to be c-axis oriented. Electron microscopy reveals that the films are not significantly smoother than films which were post-annealed at 865 °C, and that some segregation into nonsuperconducting phases had occurred. The exact mechanism by which crystallization and superconductivity occurs at such low temperatures is not yet known, but it can be speculated that the surface atoms are less constrained and thus have a smaller energy barrier to overcome in forming a crystal structure.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.102347
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  • 4
    Digitale Medien
    Digitale Medien
    CuZn-Superoxide Dismutase, Extracellular Superoxide Dismutase, and Glutathione Peroxidase in Blood from Individuals Homozygous for Asp90Ala CuZn-Superoxide Dismutase Mutation (1998)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 70 (1998), S. 0 
    Details
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract: The Asp90Ala CuZn-superoxide dismutase mutation is associated with amyotrophic lateral sclerosis (ALS) in both homo- and heterozygous form. We analyzed antioxidant enzymes in blood from 44 individuals homozygous and 114 individuals heterozygous for the Asp90Ala mutation as well as 66 blood relatives carrying the wild-type allele only. Erythrocyte CuZn-superoxide dismutase activity was reduced by 9% in the homozygous individuals, confirming previous findings on a smaller cohort. The specific activity of Asp90Ala mutant CuZn-superoxide dismutase in erythrocytes was equal to that of isolated mutant enzyme and slightly higher than that of isolated wild-type enzyme. There was no evidence for the presence of inactive mutant molecules in erythrocytes, and the lower activity is due to the occurrence of fewer active molecules. There were no significant differences between the groups in plasma extracellular superoxide dismutase content, and the erythrocyte glutathione peroxidase activities were virtually identical. Also, there were no differences in these parameters between homozygous individuals with or without ALS. There was no evidence for any association with ALS of a polymorphic extracellular superoxide dismutase mutation, Arg213Gly. The absence of response of the blood antioxidant enzymes to the Asp90Ala CuZn-superoxide dismutase mutation does not support the theory that the ALS-linked CuZn-superoxide dismutase mutations cause disease by increased oxidant stress.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1471-4159.1998.70020715.x
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  • 5
    Digitale Medien
    Digitale Medien
    Globalization and Food Security (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 69 (2004), S. 0 
    Details
    ISSN: 1750-3841
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2621.2004.tb17833.x
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  • 6
    Digitale Medien
    Digitale Medien
    Occurrence of Aspergillus umbrosus Antibodies in Danish Farmers (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 41 (1986), S. 0 
    Details
    ISSN: 1398-9995
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Antibodies to Aspergillus umbrosus were investigated in 181 Danish farmers, 137 farmers spouses and a control group of 104 male blood donors with no relation to farming. By enzyme-linked immunosorbent assay (ELISA) higher levels of IgG antibodies were found in farmers than in their spouses and in non-farming controls (P 〈 0.0001). By double immunodiffusion precipitating antibodies occurred in 11 farmers, in none of farmers' spouses and in one control subject. Farmers and farmers' spouses who were non-smokers had higher IgG antibody levels than smokers in the same groups (P 〈 0.04). Farmers more than 30 years of age had higher IgG antibody levels than younger farmers (P 〈 0.04). Farmers rearing cattle tended to have higher IgG antibody levels than farmers without cattle. No correlation between antibody levels and respiratory symptoms or lung function parameters (FEV1 or FVC) could be demonstrated.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1398-9995.1986.tb00285.x
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  • 7
    Digitale Medien
    Digitale Medien
    Crossed Immunoelectrophoretic Analysis of Precipitins to Candida albicans in Deep Candida Infection (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 4 (1975), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: By means of crossed immunoelectrophoresis with intermediate gel the precipitins to C. albicans in sera from 18 patients with deep Candida infection were compared with the findings in a control material consisting of sera from 169 'normal' controls (mainly healthy blood donors), 25 patients with oral candidiasis, 14 patients with vaginal candidiasis, and 6 persons without candidiasis giving false positive reactions by the double diffusion method. Up to 20 different precipitins were found in individual sera, and precipitins were demonstrated in all sera except in 6 'normal' controls. Of 692 precipitins 682 (98%) were identified and titrated in terms of the 78-component reference system described earlier for C. albicans. No free Candida antigens were found, but would have been detected by the method. The best criterion for discrimination between sera from patients and controls was the precipitin score, which accounts for number of precipitins and for titres. A precipitin score of more than 6 1/2 had a diagnostic sensitivity of 88.9% and a specificity of 99.5%. Eleven precipitin specificities were found solely in the patients' sera, but the highest sensitivity for a single precipitin was 33%. Until more evidence has accumulated in favour of a monospecific immunoassay it is therefore rational to use a complex antigen extract for further evaluations of diagnostic Candida serology and a short cut to standardization would be the introduction of the method used in the present study.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1975.tb03830.x
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  • 8
    Digitale Medien
    Digitale Medien
    Identification of Immunodominant Antigens during Infection with Mycobacterium tuberculosis (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 36 (1992), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: T lymphocytes isolated from mice infected with Mycobacterium tuberculosis respond vigorously to proteins secreted by the bacilli and these antigens may be of importance in the generation of protective immunity against the disease. In this study, short-term culture filtrate (ST-CF), which constitutes a complex mixture of secreted proteins, was fractionated by a modified preparative SDS-PAGE technique. The ability of each fraction to be recognized by T cells isolated from infected mice was evaluated by quantifying proliferation and IFN-γ production in cell cultures. Two molecular mass regions 4–11 and 26–35 kDa were found to possess marked stimulatory properties. Four potent single antigens were mapped within the stimulatory regions. These purified antigens stimulated T cells isolated from mice at the height of a tuberculous infection to produce large amounts of IFN-γ, Two of these stimulatory antigens belonged to lhe antigen 85 complex.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1992.tb03144.x
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  • 9
    Digitale Medien
    Digitale Medien
    Ultralow power low noise ultrahigh frequency magnetic resonance spectrometer (1992)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 63 (1992), S. 157-162 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: We describe a simple marginal oscillator that operates at ultralow power dissipation (≥20 μW at 750 MHz) for use in ultrasensitive low noise magnetic resonance detection at very low temperatures. We have operated the circuit down to 0.6 K with the sample maintained below 20 mK and in magnetic fields up to 4.0 T. The samples are maintained at mK temperatures by physically separating the sample from the rf coil.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1142980
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  • 10
    Digitale Medien
    Digitale Medien
    T-Cell Receptor Downregulation by Ceramide-Induced Caspase Activation and Cleavage of the ζ Chain (2001)
    Oxford, UK : Blackwell Science Ltd
    Scandinavian journal of immunology 53 (2001), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Regulation of T-cell receptor (TCR) cell surface expression levels is probably an important mechanism by which T-cell responsiveness is controlled. Previously, two distinct pathways for TCR downregulation have been described. One is dependent on protein kinase C (PKC) and the leucine-based receptor-sorting motif (l-based motif) of the CD3γ chain but independent of tyrosine kinases, whereas the other is dependent on the tyrosine kinase activation but independent of the PKC and the CD3γl-based motif. In this study, we describe a new pathway for TCR downregulation distinct from both the PKC/CD3γl-based motif-dependent and the tyrosine kinase-dependent pathways. This pathway is dependent on ceramide-induced activation of caspases and correlate with caspase-mediated cleavage of the ζ chain. Thus, a 10–15% downregulation of the TCR was induced following the treatment of the T cells with ceramide for 4 h. A close correlation between TCR downregulation, caspase activation, and cleavage of the ζ chain was found. Furthermore, the caspase inhibitors abolished the cleavage of the ζ chain and TCR downregulation in parallel with the inhibition of the caspase activity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-3083.2001.00852.x
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