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  • 1
    ISSN: 1520-6041
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Diabetes mellitus (type I) ; Retinopathy ; Erythrocyte aggregation ; Deformability of erythrocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In vitro measurements were carried out to study the aggregation of erythrocytes in 33 children and young adolescents, three older adolescents, and 38 adults with type I diabetes. The aggregate formation of erythrocytes in stasis was increased in adult patients with both “good” and “poor” metabolic control when compared to control values. The aggregation of red cells in all children and the younger adolescents, both those under good and poor metabolic control, did not statistically differ from those of controls. Each of the three older adolescents showed an increased aggregate formation of their erythrocytes compared to controls. All adult patients under poor metabolic control exhibited various stages of diabetic retinopathy as shown by fluorescence angiography. Only one child under poor metabolic control showed an early stage of retinopathy (stage I according to Malone). The three older adolescents showed an increased aggregate formation of their erythrocytes. These patients exhibited also stage I of retinopathy. We suggest that the increased aggregation of erythrocytes of both adult and older adolescent patients may be one of the reasons for the development of diabetic retinopathy. Moreover, the normal erythrocyte aggregation of the diabetic children and younger adolescents could help to explain the rare occurrence of microangiopathies in childhood diabetes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 44 (1936), S. 441-447 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es werden die Eiweißkörper des intaktenJensen-Sarkomgewebes und die der nekrotisierten Gewebsanteile einer Analyse bezüglich ihres Hexonbasengehaltes unterworfen, und dabei ergibt sich, daß merkwürdigerweise Tumor und Nekrose keine Unterschiede aufweisen, währenddem aus früheren Untersuchungen des Instituts hervorgeht, daß der Puringehalt in den nekrotisierten Gewebsteilen stark vermindert ist.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 47 (1938), S. 198-207 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Es wurden die Eiweißkörper des intakten Sarkomgewebes und der Nekrose einer Analyse bezüglich des Tryptophangehaltes unterworfen, wobei sich in Übereinstimmung mit unseren früheren Befunden in bezug auf den Hexonbasengehalt, eine vollkommene Gleichheit des Tryptophangehaltes zwischen Tumor und Nekrose ergab. Der Tryptophangehalt der Organe der Sarkomratte ist ebenfalls gleich groß wie bei normalen Ratten. 2. Eine Überprüfung der proteolytischen Leistung der Leber der Ratte während der Entwicklung des Tumors zeigte in Übereinstimmung mit anderen Autoren eine starke Zunahme der Kathepsinaktivität.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 47 (1938), S. 191-197 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Es wird dasJensen-Sarkom und sein nekrotisierter Anteil auf den Gehalt an Glykogen untersucht und gezeigt, daß dieser Stoff nur in minimalen Spuren vorkommt. 2. Sowohl das Sarkomgewebe als auch das Nekrosegewebe enthalten überraschenderweise eine stark wirksame Amylase.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1076
    Keywords: Dextrans ; Preterm and term newborns ; Biological half-life ; Excretion of dextran 40 and 60 ; Side effects ; Shock therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Administration of low and high molecular weight dextrans in the initial phase of shock is no longer controversial. The special conditions in newborns, however, have been insufficiently considered in planning therapy. This investigation aimed at determining the biological half-lives of dextran 40 (Rheomacrodex®) and dextran 60 (Macrodex®) in this age group. The half-life of dextran 40 was found to be 60 min and that of dextran 60 3 h. Preterm babies and newborns excrete up to 25% less dextran 40 and 60 in 24 h than infants and adults. Normal adult values for excretion are only reached towards the end of the first year of life.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 144 (1985), S. 270-272 
    ISSN: 1432-1076
    Keywords: Renal vascular malformation ; Arteriovenous fistula ; Arterial hypertension ; Polyuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report on a 9-year-old boy with a congenital renal arteriovenous fistula of the aneurysmal type, a form previously not observed in childhood. The clinical picture was unusual with severe arterial hypertension, excessive polyuria and decreased levels of serum sodium and chloride as main signs. Clinical and biochemical findings normalised after nephrectomy of the kidney involved.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1076
    Keywords: Chronic hepatitis B in children ; Hepatitis B-virus ; DNA ; Cellular cytotoxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cell-mediated immune reactions play the most important role in the pathogenesis of chronic viral and auto-immune hepatitis. Cellular cytotoxicity (CC) of peripheral blood lymphocytes against autologous hepatocytes isolated from liver biopsies was studied in 29 children with different types of hepatitis B surface antigen (HBsAg)-positive hepatitis. Children with chronic hepatitis B showed higher cytotoxicity than control patients. However, a correlation of cytotoxicity to serum amino-transferases, HBeAg-/Anti-HBe-status, and hepatitis B virus DNA in serum could not be found. Children with a higher percentage of hepatitis B core antigen (HBcAg) expression in their liver tissue presented lower CC values, and vice versa. This supports the hypothesis that virus elimination occurs via T-cell attack against HBcAg expressing hepatocytes. Furthermore, children with a longer duration of chronic hepatitis B had considerably higher cytotoxicity values. Possibly, CC plays a role in perpetuating liver damage after infection with hepatitis B virus.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0942-0940
    Keywords: Dural substitute ; vicryl (polyglactin 910) ; poly-p-dioxanone (PDS) ; cerebrospinal fluid (CSF) leaks ; posterior fossa surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Treatment of postoperative dural CSF leaks following posterior fossa surgery remains a difficult and often perplexing problem. Their management includes either non-operative management or surgical re-exploration. In order to avoid CSF leaks we developed a simple but effective method using a well-cut sheet of a vicryl-poly-p-dioxanone mesh (Ethisorb®) covering the whole defect of the craniectomy. This paper presents our technique of dural closure, experiences with and advantages of the vicryl mesh in comparison with conventional procedures using muscle patches in combination with fibrin sealant or fibrin glue alone. Attention is focused upon the frequency of postoperative complications, in particular infection rate and CSF leaks. Furthermore, histomorphological observations after implantation of a vicryl mesh are demonstrated. In conclusion, due to its specific qualities we consider the vicryl mesh as a suitable dural substitute with potential advantages over currently used material.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 524-525 (Sept. 2006), p. 13-18 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A rigorous strategy for (X-ray) diffraction stress measurements at fixedpenetration/information depths is described. Thereby errors caused by lack of penetration-depthcontrol in traditional (X-ray) diffraction (sin2ψ) measurements are annulled. The ranges ofaccessible penetration/information depths and experimental aspects are briefly discussed. The powerof the method is illustrated by the analysis of an only small stress gradient in a sputter-depositednickel layer
    Type of Medium: Electronic Resource
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