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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 40 (1962), S. 921-928 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 285-287 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 47 (1969), S. 552-556 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1440
    Keywords: Fraktur ; Spongiosadichte ; Computertomographie (CT) ; Fracture ; Trabecular bone ; Computed tomography (CT)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Computed tomography of the human radius is performed using a special purpose scanning device which incorporates a radionuclide (125I) as radiation source. Parameters describing the trabecular bone and the compact bone are determined at a distal and a diaphyseal measuring site respectively. Using this measurement technique changes in bone mineralization in the radius were studied in a group of 23 children following immobilization of an upper limb for fracture healing. An immobilization period of between three to six weeks resulted in a reduction of the relevant parameter value of up to 44% (mean 16%) in the distal part of the radius, whereas no significant change could be seen in the diaphyseal part of the same bone. Rapid remineralization of trabecular bone is indicated by the increase of the corresponding parameter value at a rate of up to several percent per week. However, in some of the patients studied complete normalization was not attained during the first six months following cast removal.
    Notes: Zusammenfassung Durch die Anwendung eines Spezialscanners mit125I als Strahlenquelle wird der menschliche Radius computertomographisch analysiert. Parameter für Spongiosa und Compacta können an einem metaphysären und diaphysären Meßort separat bestimmt werden. Mit dieser Technik wurden Änderungen der Knochenmineralisation nach Immobilisation wegen einer Fraktur an der oberen Extremität bei 23 Kindern bestimmt. Eine Immobilisationsperiode von 3–6 Wochen führte zu einer Abnahme der Spongiosadichte bis zu 44% (Mittelwert 16%) im distalen Radius, während keine signifikanten Änderungen an der Compacta der Diaphyse festzustellen waren. Eine rasche Remineralisation der Spongiosa konnte beobachtet werden, jedoch war diese bei einigen Patienten 6 Monate nach Gipsentfernung noch nicht vollständig.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 40 (1962), S. 657-660 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1076
    Keywords: Key words Schwartz-Jampel syndrome Osteochondrodysplasia ; Myotonia ; Short stature Genetic linkage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Schwartz-Jampel syndrome (SJS; chondrodystrophic myotonia; McK 255800) is a recessively inherited condition defined by myotonia, short stature, and bone dysplasia. Genetic linkage between SJS and chromosomal region 1q36-34 has been observed in several families, but the gene has not yet been identified. We studied the clinical and radiological features in 81 patients from the literature and 5 own patients trying to identify distinct subgroups. In addition, we tested genetic linkage to the SJS locus on chromosome 1 in one family with two affected sibs. We found that a group of patients have mild skeletal changes which may be secondary consequences of myotonia, while another group of patients appear to have primary bone dysplasia with myotonia. Within this latter group, there are differences in age of manifestation, clinical course and pattern of bone changes. We tentatively isolate three different types of SJS: type 1A, usually recognized in childhood, with moderate bone dysplasia, corresponding to the original descriptions of Schwartz, Jampel and Aberfeld; type 1B, similar to type 1A but recognizable at birth, with more pronounced bone dysplasia resembling Kniest dysplasia; and type 2, manifest at birth, with increased mortality and bone dysplasia resembling Pyle disease. Genetic analysis of the family with two sibs affected by SJS type␣2 showed evidence against linkage to chromosome 1p36-34. Conclusions SJS is clinically and radiologically heterogeneous. The causes of heterogeneity are not known yet but are likely to include both different mutations at the SJS locus on chromosome 1 and the presence of a second SJS locus. A tentative clinico-radiological classification can be useful for the characterization of patients and the development of genotype-phenotype correlations.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 147 (1988), S. 544-546 
    ISSN: 1432-1076
    Keywords: Serpentine elongated fibula ; Polycystic kidneys
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 5-year-old girl is reported with small stature, unusual facial appearance, polycystickidneys and elongated curved fibulae as the most impressive radiographic finding. From the close similarity with another girl described recently and discrepancies between these two patients and others with Melnick-Needles syndrome it is assumed that they may present a separate hitherto unreported entity or syndrome.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 326 (1970), S. 165-185 
    ISSN: 1435-2451
    Keywords: Subacute osteomyelitis ; Location of osteomyelitis ; X-rays ; Differential diagnosis of osteolytic processes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die charakteristischen Eigenschaften der plasmacellulären Osteomyelitis werden auf Grund eines Beobachtungsgutes von 25 Fällen des Pathologischen Institutes der Universität Zürich der Jahre 1961 bis 1965 herausgestellt. 1. Die plasmacelluläre Osteomyelitis ist eine primär chronische hämatogene Osteomyelitis mit schleichendem klinischen Verlauf, die wir als besonderen Reaktionstypus neben Brodie-Absceß und chronisch sklerosierende Osteomyelitis Garré. stellen. 2. Das vorwiegend aus Plasmazellen bestehende entzündliche Exsudat gibt der Krankheit ihren Namen. Im histologischen Schnitt können schematisch drei Zonen unterschieden werden a) Kernzone: dich plasmacellulär infiltriertes Granulationsgewebe im Zentrum des Entzündungsherdes. b) Zwischenzone: faserreiches Narbengewebe um die Kernzone. c) Mantelzone: ödematös durchtränktes Fasermark, das ebenfalls Plasmazellinfiltrate aufweist. 3. Haupterkrankungsalter sind das Kindes- und frühe Erwachsenenalter. Das männliche Geschlecht erkrankt in allen Altersklassen häufiger. 4. Die Lokalisationen der plasmacellulären Osteomyelitis entsprechen denen der akuten hämatogenen Osteomyelitis. Bevorzugt sind die Metaphysen der langen Röhrenknochen. 5. Das Röntgenbild der plasmacellulären Osteomyelitis in den langen Röhrenknochen zeigt eine Osteolyse, die von einer reaktiven Randsklerose umschlossen wird. In den kurzen Knochen ist der Befund nicht typisch. 6. Die Diagnose der plasmacellulären Osteomyelitis kann nur durch die Biopsie gestellt werden. 7. Erreger der plasmacellulären Osteomyelitis ist vorwiegend Staphylococcus aureus. 8. Therapie der Wahl ist die Auskratzung des Entzündungsherdes. Die Prognose ist gut.
    Notes: Summary The characteristic properties of plasma-cellular osteomyelitis, as based on the findings from material of 25 such cases gathered at the Institute of Pathology of the University of Zurich from 1961 to 1965, are presented. 1. Plasma-cellular osteomyelitis is a primary, chronic, haematogenous osteomyelitis demonstrating an insiduous clinical picture. We see this entity as a specific reaction — response such as is seen with the Brodie abscess and the sclerosing osteomyelitis of Garré. 2. The name, plasma-cellular osteomyelitis, is derived from the microscopic picture as revealed in a slide study whereby three zones are distinguishable, to wit: a) Central Zone: Granulation tissue in the center of the inflammatory focus densely infiltrated with plasma cells. b) Intermediate Zone: A fiber-rich scar tissue around the central zone. c) Peripheral Zone: Fibrous bone marrow oedematously imbibed with a proteinrich fluid. 3. Morbidity is most frequent amongst children and young adults. The male is more frequently affected, this, despite the age bracket. 4. The localisations of plasma-cellular osteomyelitis correspond to those of the acute haematogenous form: sites of preference being the metaphyses of the long bones. 5. The X-ray picture of the disease, as evidence in the long bones, shows central osteolytis, which is free from sequesters, evidencing a peripheral sclerosis. 6. Diagnosis of plasma-cellular osteomyelitis can be ascertained only through biopsy. 7. Staphylococcus aureus is the predominant infecting agent. 8. Curettage of the focus of infection presents the therapy of choice. The prognosis is good.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Der Orthopäde 26 (1997), S. 59-66 
    ISSN: 1433-0431
    Keywords: Schlüsselwörter Hüftluxation ; Kernspintomographie ; Computertomographie ; Reposition ; Normalwerte ; Key words Hip dysplasia ; Magnetic resonance imaging ; Computed tomography ; Reduction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Magnetic resonance imaging (MRI) and computed tomography (CT) are useful techniques for the objective documentation of the relation between the femoral head and the acetabulum after closed or open reduction of a developmental dislocation of the hip joint. Before the ossification nucleus of the femoral head is sufficiently developed, MRI is preferred. For the evaluation of reduction from the 2nd year on, MRI and CT are equivalent. However, in older children MRI may also be indicated for the evaluation of cartilaginous structures or the diagnosis of femoral head necrosis. CT in older patients may also be useful for 30 analysis of bony structures, e. g. for planning complex osteotomies.
    Notes: Zusammenfassung Kernspintomogramm (MRI) und Computertomogramm (CT) sind geeignete Methoden zur objektiven Erfassung der Zentrierung nach offener oder geschlossener Reposition einer Hüftgelenkluxation und können in besonderen Situationen die Arthrographie ersetzen. Bis zur ausreichenden Ossifikation der Hüftkopfkerne, d. h. im 1. Lebensjahr, ist dem MRI der Vorzug zu geben. Vom 2. Lebensjahr an ist für die Beurteilung des Repositionsergebnisses das CT gleichwertig. Beim älteren Kind kann das MRI aber auch indiziert sein für die Beurteilung der knorpeligen Hüftstrukturen oder zur Diagnose einer Femurkopfnekrose. In höherem Alter können durch eine aufwendige CT-Untersuchung die knöchernen Verhältnisse auch dreidimensional dargestellt werden, z. B. zur Planung komplexer Korrekturosteotomien.
    Type of Medium: Electronic Resource
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