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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 177 (1987), S. 27-32 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leukocidin in F. necrophorum infections.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A new experimental technique is developed by combining a flash photolysis method with a laser-photodiode system to measure the velocity of the flow of thin liquid films. The technique is applied to the measurement of the velocity of the liquid-fuel film within the intake pipe of an internal combustion engine operated under firing condition. The results show that the velocity of the fuel film is of the order of 1/100 of the mean air velocity inside the intake pipe.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0942-0940
    Keywords: ENU-induced glioma ; vasculature ; bromodeoxyuridine ; Evans blue dye ; blood-brain barrier ; mannitol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Vascular permeability and proliferative activity of ethylnitrosourea (ENU)-induced rat brain tumours were studied by intravenous injection of Evans blue dye (EB) and by bromodeoxyuridine (BrdU) uptake examinations. Tumours induced by ENU showed various histologial types, and they were oligodendrogliomas, mixed oligo-astrocytomas, mixed oligo-ependymomas, astrocytomas, anaplastic astrocytomas, polymorphic gliomas, and ependymomas. The labelling indexes (LIs: the ratio of BrdU-labelled cells to total cells) of tumour and vascular component cells in the tumour were high in anaplastic astrocytomas, polymorphic gliomas and ependymomas, but low in oligodendrogliomas. EB stained anaplastic astrocytomas, polymorphic gliomas and ependymomas deeply, but did not penetrate oligodendrogliomas. In mixed gliomas, EB staining and the LIs of tumour cells were not uniform. After intracarotid infusion of hyperosmolar mannitol into tumour-bearing rats, tumour staining with EB and the LIs of tumour cells were not increased, whereas the penetration of EB into the normal brain was drastically increased. Therefore it is not likely that the delivery of chemotherapeutic drugs to the tumour could be increased by intracarotid infusion of hyperosmolar manitol. Our data suggest that the vascular permeability of tumour vessels is highly correlated with the high proliferative activity of tumour and its vascular cells.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0942-0940
    Keywords: Bromodeoxyuridine uptake examination ; meningioma ; proliferative activity ; recurrence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Proliferative activity of meningiomas was examined in 12 consecutive cases by administering bromodeoxyuridine (BrdU) before surgical removal and by immunohistochemical staining of the removed tumours using anti-BrdU monoclonal antibody (anti-BrdU MAb) to detect BrdU-labelled tumour cells. The 12 cases consisted of 6 with a primary tumour and 6 with a recurrent tumour. All of the tumours contained labelled cells and the labelling index (LI) was obtained in each tumour. The highest average LI was 13.6% and the second highest was 9.0% both in recurrent cases of histologically malignant meningothelial meningioma. The high LIs of both cases were thought to correspond well with the rapid recurrence of the tumour. The average LI of a case of recurrent haemangiopericytic tumour was 2.0%, and that of a case of meningioma associated with von Recklinghausen disease was 1.5%. The other 8 meningiomas showed the average LIs ranging from 0.1 to 0.9%, which were considered to be the LIs of usual benign meningiomas. The results of the BrdU uptake examination was considered to reflect well the clinical behaviour of meningiomas. The usefulness of the BrdU uptake examination in brain tumours, which can be employed in the clinical practice without any serious side-effects, is stressed.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0942-0940
    Keywords: Keywords: Trigeminal neuralgia; microvascular decompression; recurrence; Teflon felt; re-operation; sling retraction technique.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ The causes of recurrence after microvascular decompression for trigeminal neuralgia and the results of re-operations were studied in 6 cases. Eighty-two patients with trigeminal neuralgia were operated on through microvascular decompression using the technique of interposing Teflon felt between the offending artery and the pons and/or nerve. Recurrence occurred in 14 cases (17.1%) and re-operations were carried out in 6 severe cases at which time the sling retraction technique was used. At the second operation, the adhesion of the interposed Teflon felt was found at the trigeminal nerve in all cases and the adhesions were the main cause of recurrence. The Teflon felt was dissected from the nerve, and the sling of the Teflon felt adhering to the offending arteries was fixed to the tentorium in order to transpose the arteries and avoid re-adhesion. All cases resulted in an excellent relief from pain and experienced no pain for at least 2 years. The intra-operative findings of our cases indicated that the microvascular decompression using the interposing technique may result in adhesion of the prosthesis to the nerve and thus eventually lead to recurrence. Our surgical experience also suggests that such recurrent cases should be re-operated on using the sling retraction technique instead of the interposing technique, even for the first microvascular decompression procedure.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0942-0940
    Keywords: Adenosine ; ATP ; regional cerebral blood flow ; RG-C6 glioma ; intracarotid administration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied the effect of intravenous and intracarotid infusion of adenosine and adenosine triphosphate (ATP) on the regional blood flow of intracerebrally transplanted RG-C 6 tumours in rats, using the hydrogen clearance method. The intracarotid administration of adenosine or ATP selectively increased blood flow in the tumour, but did not produce any significant change either in the regional cerebral blood flow of the extratumoural ipsilateral hemisphere or in the ipsilateral hemisphere without tumour. The intracarotid administration of ATP at a dose of 10 Μg/kg/min produced the most effective increase in the tumour blood flow (+51.5± 16.8%). In contrast, both the intravenous administration of adenosine and that of ATP failed to increase tumour blood flow. These results may possibly indicate that intracarotid administration of the adenosine or ATP might contribute in selectively enhancing the delivery of anti-cancer agents to malignant brain tumours.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 47 (1988), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract This report describes a dot enzyme-linked immunosorbent assay (Dot-ELISA) for detecting circulating antigens in the sera of dogs infected with Dirofilaria immitis (D. immitis). Circulating D. immitis antigens could be detected in 24 of 25 infected dogs. The remaining animal had two immature worms. However, non-infected dogs and dogs infected with other parasites were all negative, Few cross-reactions to different parasite antigens were observed. The advantages of the Dot-ELISA include; 1) there is no need for pretreatment and dilution of sera and samples could be immediately bound to nitrocellulose paper set into microfiltration apparatus, 2) this assay could be carried out within 2 h at room temperature, 3) the resulting enzyme-reaction could be measured by both visual observation and densitometric reading.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Using an antibody raised against d-glucose dehydrogenase (EC 1.1.99.17) purified from Pseudomonas fluorescens, immuno-cross-reactivity with the enzymes from several bacterial strains and localization of the enzyme in Escherichia coli were examined. The antibody cross-reacted with glucose dehydrogenases from various Gram-negative bacteria examined. As a result, it became apparent that the enzymes from Gluconobacter, Acetobacter, Pseudomonas and Acinetobacter, which existed as holoenzymes in the membranes, had lower molecular weights than those from E. coli and Klebsiella, which were apoenzymes.Treatment with trypsin of right-side out and inside-out membrane vesicles from E. coli clearly demonstrated that d-glucose dehydrogenase was located on the outer surface of the cytoplasmic membrane of E. coli, as had been suggested for Pseudomonas.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    International journal of clothing science & technology 12 (2000), S. 205-213 
    ISSN: 0955-6222
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In order to establish an objective method of evaluating ladies' garment fabrics by connecting the mechanical properties of ladies' garment fabrics to subjective evaluation, subjective assessments were examined by judges who work at textile mills or in the textile trade. We examined a method of deriving objective equations, a total hand value (THV) equation and a total appearance value (TAV) equation. The THV equation was derived directly from the mechanical properties of the fabrics and the TAV equation was derived from three mechanical parameters which are related to the beauty of garment appearance. In the case of the THV objective equation, the accuracy of regression was high within the same groups of judges; however, in the case of the TAV objective equation, accuracy was slightly low. Because there were few subjects and that caused deviation, the accuracy of prediction was slightly low; however, the objective evaluation was adequate.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 744-746 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Receiving higher emphasis on the neutral beam (NB) off-axis current drive, the NB system is being highlighted for the steady state operation of the International Thermonuclear Experimental Reactor (ITER). To fulfill the physics requirement of heating and current drive, the NB system delivers ∼50 MW of D0 beams at 1 MeV into the ITER plasmas. The NB injector was designed so as to minimize the axial length, to avoid cost impact on the building. It was estimated by nuclear analyses that the insulation gas around the beam source would cause radiation induced conductivity, which would result in a power dissipation of 〉100 kW in the gas itself. As a result the present design utilizes vacuum insulation around the beam source. Since the vacuum pressure inside/outside the beam source ranges 10−1–10−2 Pa, both gas (glow) and vacuum arc discharges are taken into account in the design. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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