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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 119 (2000), S. 0 
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The Rysto gene from Solanum stoloniferum introduced into potato cultivars (Solanum tuberosum L. ssp. tuberosum) confers resistance to potato virus A, potato virus V and potato virus Y (PVY). In addition to PVY, tobacco etch virus (TEV) and a TEV construct that encodes β-glucuronidase (TEV-GUS) were inoculated to determine the inheritance of resistance to these viruses in progenies obtained from potato cultivars containing the Rysto gene. While cultivars ‘Karlena’ and ‘Delikat’ were susceptible, ‘Bettina’ and clone 927eY were resistant to PVY, TEV and TEV-GUS, as determined by enzyme linked immunosorbent assay, biotest and GUS assay, respectively. The segregation ratios obtained from the progenies of ‘Bettina’בDelikat’ and 816eY בKarlena’ indicate that resistances to PVY and TEV are governed by one dominant gene or two genes tightly linked in coupling phase. Evidently, Rysto confers broad spectrum resistance to potyviruses. TEV resistance could be reliably detected 4 days after inoculation with the TEV-GUS construct by GUS assay. Therefore, the GUS-tagged TEV construct can be used for early selection for resistances based on the gene Rysto or closely linked genes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 115 (2001), S. 1995-1999 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: In this paper we present a new approach to calculate optical spectra, which for the first time uses a polarization dependent functional within current density functional theory (CDFT), which was proposed by Vignale and Kohn [Phys. Rev. Lett. 77, 2037 (1996)]. This polarization dependent functional includes exchange-correlation (xc) contributions in the effective macroscopic electric field. This functional is used to calculate the optical absorption spectrum of several common semiconductors. We achieved in all cases good agreement with experiment. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Pseudomonas aeruginosa infection is a serious complication in patients with cystic fibrosis and in immunocompromised individuals. Here we show that P. aeruginosa infection triggers activation of the acid sphingomyelinase and the release of ceramide in sphingolipid-rich rafts. Ceramide reorganizes ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Acne is a common skin disorder, but epidemiological data from the general population obtained by examination are scarce. Clinical experience suggests an association between smoking and acne, although confirmatory evidence from appropriate studies is lacking.Objectives To determine the prevalence and demographic factors of acne in a general population sample and to investigate the association of smoking and acne on a qualitative and quantitative level.Methods In a cross-sectional study, 896 citizens (aged 1–87 years, median 42) of the City of Hamburg were dermatologically examined. The prevalence and severity of acne were recorded and further information on demographic variables, medical history, and alcohol and cigarette consumption were obtained by a standardized interview.Results According to the clinical examination, acne was present in 26·8% overall, and was more prevalent in men (29·9%) than women (23·7%) (odds ratio, OR 1·37, 95% confidence interval, CI 1·01–1·87). Prevalence followed a significant linear trend over age with peak prevalence between 14 and 29 years (P 〈 0·001). The reported age at onset was significantly lower in women than men (P = 0·015). According to multiple logistic regression analyses acne prevalence was significantly higher in active smokers (40·8%, OR 2·04, 95% CI 1·40–2·99) as compared with non-smokers (25·2%). A significant linear relationship between acne prevalence and number of cigarettes smoked daily was obtained (trend test: P 〈 0·0001). In addition, a significant dose-dependent relationship between acne severity and daily cigarette consumption was shown by linear regression analysis (P = 0·001).Conclusions Smoking is a clinically important contributory factor to acne prevalence and severity.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 228 (1970), S. 636-639 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Certain types of clays may have played a catalytic part in the evolution of polypeptides. The active forms of ammo-acids, concentrated by adsorption on the clay particle surface, are shown to condense to form polypeptides of different but discrete ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 28 (1972), S. 301-302 
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 250 (1972), S. 142-147 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Summary The photodegradation of poly(methyl methacrylate) and polystyrene in solution is strongly influenced by the interaction polymer-solvent. The rate of degradation for poly(methyl methacrylate) in various solvents decreases in air as well as in nitrogen in the order 1,4-dioxane 〉tetrahydrofuran〉chloroform. For polystyrene another order of influence of the solvents is valid: chloroform≫1,4-dioxane〉tetrahydrofuran=0, whereby the degradation in air is faster than in nitrogen. The influence of retardation of low molecular charge-transfer complexes of maleic anhydride (acceptor) and 1,4-dioxane or tetrahydrofuran (donors) on the photodegradation of poly(methyl methacrylate) is independent on the atmosphere. The same is valid for the influence of the complex of maleic anhydride with poly(ethylene glycol) on the degradation of polystyrene in chloroform. The content of ether oxygen in donor is primary responsible for the measure of the retardation effect of the complex on the degradation of the polymer. For poly(methyl methacrylate) in chloroform with maleic anhydride as acceptor the order of the donor efficiency is as follows: poly(ethylene glycol)〉ethylene glycol monomethyl ether〉ethylene glycol=0. The electron affinity of the acceptor (related to 1,4-dioxane as donor) shares the responsibility for the complex retardation effect on the photodegradation of the polymer.
    Notes: Zusammenfassung Der Photoabbau von Polymethylmethacrylat und Polystyrol in Lösung wird stark durch die Wechsel-wirkung Polymeres-Lösungsmittel beeinflußt. Die Abbaugeschwindigkeit von Polymethylmethacrylat in verschiedenen Lösungsmitteln nimmt in Luft sowie unter Stickstoff in der Reihenfolge 1,4-Dioxan〉Tetrahydrofuran 〉Chloroform ab. Beim Polystyrol ist die Reihenfolge des Lösungsmitteleinflusses anders: Chloroform ≫1,4-Dioxan〉Tetrahydrofuran=0, wobei der Abbau unter Luft schneller als unter Stickstoff verläuft. Der retardierende Einfluß des niedermolekularen Elektronen-Donator-Acceptor-Komplexes aus Maleinsäureanhydrid (Acceptor) und 1,4-Dioxan bzw. Tetrahydrofuran (Donatoren) ist beim Photoabbau von Polymethylmethacrylat unabhängig von der Atmosphäre. Dasselbe gilt für den Einfluß des Komplexes Polyäthylenglycol-Maleinsäureanhydrid auf den Abbau von Polystyrol in Chloroform. Der Äther-Sauerstoffgehalt im Donator ist für das Maß der retardierenden Wirkung des Komplexes auf den Abbau des Polymeren primär verantwortlich. Bei Polymethylmethacrylat in Chloroform mit Malein-säureanhydrid als Acceptor ist die Reihenfolge der Donatoren-Wirksamkeit: Polyäthylenglycol〉Äthy-lenglycolmonomethyläther 〉Äthylenglycol=0. Die Elektronenaffinität der Acceptoren (bezogen auf 1,4-Dioxan als Donator) ist für die retardierende Wirkung des Komplexes auf den Photoabbau des Polymeren mitverantwortlich.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Computational mechanics 25 (2000), S. 627-634 
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The derivation of a Green's function for steady-state heat conduction in anisotropic bimaterials is presented. The Green's function is obtained through a Fourier representation to obtain both free-space, singular parts and region-dependent, regular parts. To obtain the region-dependent parts of the Green's function, the homogeneous solution is written using the virtual force method. Full details of the necessary inversion integrals are provided. The Green's function is shown to degenerate to the usual logarithmic potential for steady-state heat conduction in isotropic solids. The normal derivatives necessary for implementation of the Green's function in boundary integral equations are provided, and an example calculation of the Green's function in a quartz-copper material system is presented.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1440
    Keywords: HAA positive acute hepatitis ; Cellular immunity ; Hepatitis associated antigen ; Liver specific antigens ; Migration inhibition test ; Autoimmunity ; HAA-positive akute Hepatitis ; Celluläre Immunität ; Hepatitis assoziiertes Antigen ; Leberspezifische Antigene ; Migrations Inhibitions-Test ; Autoimmunität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die cellulären Immunreaktionen gegenüber homologen leberspezifischen Proteinen (HLP) und dem Hepatitis-assoziierten Antigen (HAA) wurden bei Patienten mit akuter HAA-positiver Hepatitis unter Verwendung des Leukocytenmigrationstestes untersucht. Die Migration war bei 30% der Patienten inhibiert, wenn HLP als Antigen verwandt wurde. Mit HAA zeigten 64% der Patienten, die später im Serum HAA-negative wurden, einen Migrationsindex unter 0,7 und 15% eine Stimulation. Die Häufigkeit der Migrationsinhibition betrug nur 22% bei den Patienten, die persistierende HAA-Antigenträger waren. Nur bei 20% der Fälle war der Test gegenüber beiden Antigenen anormal. Aus den Ergebnissen kann geschlossen werden, daß 1. eine celluläre Immunität gegenüber HAA öfter bei Patienten auftritt, die das Antigen verlieren. 2. die verzögerte Immunität gegenüber den beiden getesteten Antigenen nicht miteinander in Beziehung steht. 3. die Toleranz gegenüber homologen leberspezifischen Antigenen bei der akuten HAA-positiven Hepatitis gebrochen werden kann. Dieser Befund weist eindeutig auf den Einfluß der Virusinfektion für die Entstehung einer Autoimmunität bei Lebererkrankungen hin.
    Notes: Summary The cell-mediated immune responses towards homologous, liver-specific antigens (HLP) and hepatitis-associated antigen (HAA) were studied in patients with acute HAA-positive hepatitis using the leukocyte migration test. The migration was inhibited in 30% of the patients when HLP was used. With HAA 64% of the patients—who later became negative for HAA in their serum-exhibited migration indices below 0.7 and 15% of them a stimulation. The incidence of migration inhibition was as low as 22% in patients who were persistently positive for HAA in their serum. In 20% of the cases only was the test abnormal for both antigens. It can be concluded from our results that 1. cellular immune reactions towards HAA occur more often in patients who clear the antigen. 2. the delayed type immunity against the two antigens tested seems not to be correlated. 3. the tolerance against homologous liver specific antigens can be broken in acute HAA-positive hepatitis. This finding clearly points out the influence of viral infection for the development of autoimmunity in liver diseases.
    Type of Medium: Electronic Resource
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